EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Astrotactin-2 (Fragment)ASTN2H0Y3A82
Ataxin-1 (Spinocerebellar ataxia type 1 protein)ATXN1 ATX1 SCA1P542532
Atlastin-3 (EC 3.6.5.-)ATL3Q9UFL12
ATP synthase F(0) complex subunit C1, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P1) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C1) (ATPase protein 9) (ATPase subunit c)ATP5G1P054962
ATP synthase mitochondrial F1 complex assembly factor 1 (ATP11 homolog)ATPAF1 ATP11Q5TC122
ATP synthase mitochondrial F1 complex assembly factor 2 (ATP12 homolog)ATPAF2 ATP12 LP3663Q8N5M12
ATP synthase peripheral stalk subunit OSCP (Fragment)ATP5POH7C0682
ATP synthase subunit alpha, mitochondrialATP5A1 ATP5A ATP5AL2 ATPMQ53XX62
ATP synthase subunit alpha, mitochondrialATP5A1 ATP5A ATP5AL2 ATPMA8K0922
ATP synthase subunit alpha, mitochondrialATP5F1AK7ESA02
ATP synthase subunit alpha, mitochondrial (Fragment)ATP5F1AK7EQH42
ATP synthase subunit beta, mitochondrial (EC 3.6.3.14)ATP5B ATPMB ATPSBQ142832
ATP synthase subunit beta, mitochondrial (Fragment)ATP5F1BH0YI372
ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit)ATP5C1 ATP5C ATP5CL1Q6I9V22
ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)ATP5JQ6NZ592
ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12)ABCA12 ABC12Q86UK02
ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5)ABCB5Q2M3G02
ATP-binding cassette sub-family B member 8, mitochondrialABCB8C9JYI32
ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR)ABCD2 ALD1 ALDL1 ALDR ALDRPQ9UBJ22
ATP-binding cassette sub-family E member 1 (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I)ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40Q138642
ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)ABCF1 ABC50Q69YP62
ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)ABCG2 ABCP BCRP BCRP1 MXRQ4W5I32
ATP-binding cassette sub-family G member 5 (Sterolin-1)ABCG5Q9H2222
ATP-citrate synthase (Fragment)ACLYK7ESG82
ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase)PFKLQ96A642
ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (CHL1-related protein 1) (hCHLR1) (DEAD/H-box protein 11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2)DDX11 CHL1 CHLR1 KRG2Q96FC92
ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein)PIF1 C15orf20Q9H6112
ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II)DHX9 DDX9 LKP NDH2Q5VY622
ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A)DDX19A DDX19LB2RPL02
ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49)DDX39A DDX39Q9H5W02
ATP-dependent RNA helicase DDX3XDDX3XA0A0D9SFB32
ATP-dependent RNA helicase DHX8DHX8K7EQH72
ATP-dependent RNA helicase DQX1 (EC 3.6.4.12) (DEAQ box polypeptide 1)DQX1Q8TE962
ATP2B1 protein (Fragment)ATP2B1Q58F242
ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (Thorase)ATAD1 FNP001Q8NBU52
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H, isoform CRA_c (V-type proton ATPase subunit H)ATP6V1H hCG_27354G3V1262
Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1)ACKR3 CMKOR1 CXCR7 GPR159 RDC1P251062
Autism susceptibility gene 2 proteinAUTS2 KIAA0442Q8WXX72
Autophagy protein 5ATG5 DKFZp686F0183Q7Z3H32
Autophagy-related protein 101ATG101 C12orf44 PP894Q9BSB42
B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)CD79B B29 IGBP402592
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)BCL9O005122
B-cell CLL/lymphoma 9-like protein (B-cell lymphoma 9-like protein) (BCL9-like protein) (Protein BCL9-2)BCL9L DLNB11Q86UU02
B-cell receptor-associated protein 31 variant (Fragment)0Q53HT62
B-cell scaffold protein with ankyrin repeatsBANK1Q8NDB22
B2 microglobulin (HLA class I histocompatibility antigen, alpha chain G)HLA-G HLA-G2.2Q316112
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)BIRC2 API1 MIHB RNF48Q134902
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)BAG2Q08AS92
BAH and coiled-coil domain-containing protein 1BAHCC1F8WBW82
Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G)EPB41L2Q68DV22
Band 4.1-like protein 3EPB41L3A0A0A0MRA82
Bardet-Biedl syndrome 1 proteinBBS1E9PQK22
Bardet-Biedl syndrome 12 proteinBBS12 C4orf24Q6ZW612
Bardet-Biedl syndrome 4 proteinBBS4Q96RK42
Basic helix-loop-helix domain-containing protein USF3 (Upstream transcription factor 3)USF3 KIAA2018Q68DE32
Basic helix-loop-helix transcription factor scleraxis (Class A basic helix-loop-helix protein 41) (bHLHa41) (Class A basic helix-loop-helix protein 48) (bHLHa48)SCX BHLHA41 BHLHA48 SCXA SCXBQ7RTU72
Basic leucine zipper and W2 domain-containing protein 1 (Fragment)BZW1C9IZ802
Basic leucine zipper and W2 domain-containing protein 2BZW2 HSPC028 MSTP017Q96JW52
Basic salivary proline-rich protein 1 (Salivary proline-rich protein) [Cleaved into: Proline-rich peptide II-2; Basic peptide IB-6; Peptide P-H]PRB1P042802
Basic salivary proline-rich protein 2 (Salivary proline-rich protein) (Con1 glycoprotein) [Cleaved into: Basic proline-rich peptide IB-1; Basic proline-rich peptide P-E (IB-9); Basic proline-rich peptide IB-7; Basic proline-rich peptide IB-8c (Basic peptide P-F); Basic proline-rich peptide IB-4]PRB2P028122
Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147)BSG UNQ6505/PRO21383A6NJW12
BDP-1 protein (Fragment)0O755442
BEN domain-containing protein 3BEND3 KIAA1553Q5T5X72
BEN domain-containing protein 5BEND5 C1orf165Q7L4P62
BEN domain-containing protein 6BEND6 C6orf65Q5SZJ82
Beta actin variant (Fragment)0Q53G992
Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1)BCO1 BCDO BCDO1 BCMO1Q9HAY62
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (EC 2.4.1.102) (Core 2-branching enzyme 3) (Core2-GlcNAc-transferase 3) (C2GnT3)GCNT4Q9P1092
Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)RFNGQ9Y6442
Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N-acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T)B4GALNT1 GALGT SIAT2Q009732
Beta-2-glycoprotein 1 (Fragment)APOHJ3KS172
Beta-2-microglobulinB2MF5H6I02
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]B2M CDABP0092 HDCMA22PQ9UD482
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)SNTB2 D16S2531E SNT2B2 SNTLQ9BY092
Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor)ADRB3 ADRB3R B3ARP139452
Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf-4)CTNNBIP1 ICATQ9NSA32
Beta-defensin 114 (Beta-defensin 14) (DEFB-14) (Defensin, beta 114)DEFB114 DEFB14Q30KQ62
Beta-galactosidaseGLB1E7EQ292
Beta-galactosidase (EC 3.2.1.23)0B7Z6Q52
Beta-galactosidase (Fragment)GLB1C9J5392
Beta-galactoside alpha-2,6-sialyltransferase 2 (Alpha 2,6-ST 2) (EC 2.4.99.1) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2) (ST6Gal II) (ST6GalII) (hST6Gal II) (Sialyltransferase 2)ST6GAL2 KIAA1877 SIAT2Q96JF02
Beta-globin (Fragment)HBBQ86VF02
Beta-hexosaminidase (EC 3.2.1.52)HEXAH3BP202
Beta-hexosaminidase (EC 3.2.1.52)HEXAH3BS102
Beta-hexosaminidase (EC 3.2.1.52)0B4DVA72
Beta-hexosaminidase subunit alpha (Fragment)HEXAH3BU852
Bid (Fragment)0B1PL872
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6JMJD6K7EJU92
Bifunctional purine biosynthesis protein PURH (Fragment)ATICC9JLK02
Bifunctional purine biosynthesis protein PURH [Cleaved into: Bifunctional purine biosynthesis protein PURH, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]ATIC PURH OK/SW-cl.86Q53S282
Bile salt-activated lipaseCELX6R8682
Bleomycin hydrolase (Fragment)BLMHK7ES022
BLOC-1-related complex subunit 6 (Lysosome-dispersing protein) (Lyspersin)BORCS6 C17orf59Q96GS42
BLOC-1-related complex subunit 8 (MEF2B neighbor)BORCS8 MEF2BNBQ96FH02
Bloom syndrome proteinBLMH0YNU52
BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2)BMPER KIAA1965Q8N8U92
BolA-like protein 1 (hBolA)BOLA1 CGI-143Q9Y3E22
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)BMP2 BMP2AP126432
Bone morphogenetic protein 8A (BMP-8A)BMP8AQ7Z5Y62
BPI fold-containing family A member 2 (Parotid secretory protein) (PSP) (Short palate, lung and nasal epithelium carcinoma-associated protein 2)BPIFA2 C20orf70 SPLUNC2 UNQ510/PRO1025Q96DR52
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