EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
BPI fold-containing family B member 1 (Fragment)BPIFB1A2A2R02
BPI fold-containing family B member 4 (Ligand-binding protein RY2G5) (Long palate, lung and nasal epithelium carcinoma-associated protein 4)BPIFB4 C20orf186 LPLUNC4P598272
Brain-derived neurotrophic factor (BDNF) (Abrineurin)BDNFP235602
Brain-specific angiogenesis inhibitor 1BAI1O145142
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L0M42
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L1C82
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L5262
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 (BAI1-associated protein 2-like protein 2) (Planar intestinal- and kidney-specific BAR domain protein) (Pinkbar)BAIAP2L2 UNQ9336/PRO34007Q6UXY12
Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)BCAR3 NSP2 SH2D3B UNQ271/PRO308O758152
Breast cancer metastasis-suppressor 1BRMS1Q9HCU92
Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40)BRMS1LQ5PSV42
Breast carcinoma amplified sequence 1, isoform CRA_c (Breast carcinoma-amplified sequence 1)BCAS1 hCG_37358G3XAF72
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 variant (Fragment)0Q59FY52
Bromodomain adjacent to zinc finger domain protein 2ABAZ2AF8VU392
Bromodomain and PHD finger-containing protein 3BRPF3 KIAA1286Q9ULD42
Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)BRDTQ58F212
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)BRD8 SMAP SMAP2Q9H0E92
BSD domain-containing protein 1BSDC1 UNQ2494/PRO5781Q9NW682
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (Fragment)KCTD13I3L3K42
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)BTBD1 C15orf1 NS5ATP8Q9H0C52
BTB/POZ domain-containing protein 17 (Galectin-3-binding protein-like)BTBD17A6NE022
BTB/POZ domain-containing protein KCTD8KCTD8Q6ZWB62
Burkitt's lymphoma translocation t(2;8) encoding kappa light chain,. Chromosome 8q+ break point (Fragment)0A0N2N32
Butyrophilin subfamily 1 member A1 (BT)BTN1A1 BTNQ134102
Butyrophilin subfamily 3 member A2 (Fragment)BTN3A2E9PRR12
Butyrophilin-like protein 3 (Butyrophilin-like receptor)BTNL3 BTNLR COLF4100 UNQ744/PRO1472Q6UXE82
BXDC2 protein (Fragment)BXDC2A0JLQ52
BZW1 protein variant (Fragment)0Q53FN72
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]MTHFD1 MTHFC MTHFDQ86VC92
C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)CCR2 CMKBR2P415972
C-C chemokine receptor type 7 (C-C CKR-7) (CC-CKR-7) (CCR-7) (BLR2) (CDw197) (Epstein-Barr virus-induced G-protein coupled receptor 1) (EBI1) (EBV-induced G-protein coupled receptor 1) (MIP-3 beta receptor) (CD antigen CD197)CCR7 CMKBR7 EBI1 EVI1P322482
C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)]CCL22 MDC SCYA22 A-152E5.1O006262
C-C motif chemokine 24 (CK-beta-6) (Eosinophil chemotactic protein 2) (Eotaxin-2) (Myeloid progenitor inhibitory factor 2) (MPIF-2) (Small-inducible cytokine A24)CCL24 MPIF2 SCYA24O001752
C-Jun-amino-terminal kinase-interacting protein 4SPAG9A0A087X2D82
C-reactive proteinCRPQ5VVP72
C-terminal-binding protein 1 (Fragment)CTBP1D6RAX22
C-type lectin domain family 11 member ACLEC11AM0R0812
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor)CLEC4A CLECSF6 DCIR LLIR HDCGC13PQ9UMR72
C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299)CLEC4M CD209L CD209L1 CD299Q9H2X32
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1)CLEC7A BGR CLECSF12 DECTIN1 UNQ539/PRO1082Q9BXN22
C-X-C motif chemokine (Fragment)0D3JV422
C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)]CXCL10 INP10 SCYB10P027782
C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]CXCL2 GRO2 GROB MIP2A SCYB2P198752
C2 domain-containing protein 3C2CD3Q4AC942
C9orf126 protein (Protein SCAI)C9orf126 SCAIQ3SXZ02
Cactin (Renal carcinoma antigen NY-REN-24)CACTIN C19orf29Q8WUQ72
CAD protein (Fragment)CADH7C2E42
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]CDH1 CDHE UVOQ9UII82
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]CDH1 CDHE UVOQ161942
Cadherin-10 (T2-cadherin)CDH10Q9Y6N82
Cadherin-18 (Cadherin-14)CDH18 CDH14Q136342
Cadherin-22 (Pituitary and brain cadherin) (PB-cadherin)CDH22 C20orf25Q9UJ992
Cadherin-related family member 1 (Photoreceptor cadherin) (prCAD) (Protocadherin-21)CDHR1 KIAA1775 PCDH21 PRCADQ96JP92
Calcipressin-1 (Adapt78) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Regulator of calcineurin 1)RCAN1 ADAPT78 CSP1 DSC1 DSCR1P538052
Calcitonin gene-related peptide 2 (Beta-type CGRP) (Beta-CGRP) (Calcitonin gene-related peptide II) (CGRP-II)CALCB CALC2P100922
Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28)CIB1 CIB KIP PRKDCIPO006932
Calcium load-activated calcium channel (Transmembrane and coiled-coil domains 1, isoform CRA_b)TMCO1 hCG_1766418J9JIE62
Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4)MICU1 CALC CBARA1Q9BPX62
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)CALCOCO2 NDP52Q6IBN92
Calcium-dependent secretion activator 2CADPS2A0A087X1P32
Calcium-dependent secretion activator 2CADPS2F8W8P52
Calcium-responsive transcription factor (Fragment)CARFC9JT992
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Cam-PDE 1A) (EC 3.1.4.17) (61 kDa Cam-PDE) (hCam-1)PDE1AP547502
Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, isoform CRA_e (Calcium/calmodulin-dependent protein kinase type II subunit delta)CAMK2D hCG_22679D6R9382
Calcium/calmodulin-dependent protein kinase II gamma isoform 6 variant (Fragment)0Q59FI62
Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase I beta) (CaM kinase IB) (CaM-KI beta) (CaMKI-beta) (Pregnancy up-regulated non-ubiquitously-expressed CaM kinase)PNCKQ6P2M82
Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein)CACYBP S100A6BP SIP PNAS-107B2ZWH22
Calcyphosin (Calcyphosine, isoform CRA_b)CAPS hCG_23051K7EL212
CALM3 protein0Q9BRL52
Calmodulin-1CALM1 CALM CAM CAM1Q613792
Calmodulin-1CALM1E7ETZ02
Calnexin (Fragment)CANXD6RFL12
Calpain small subunit 1CAPNS1K7EKD82
Calpain small subunit 1CAPNS1K7EMQ12
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)CAPNS1 CAPN4 CAPNSQ96EW02
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)CAPN1 CANPL1 PIG30Q2TTR02
Calpain-1 catalytic subunit (Fragment)CAPN1E9PLX02
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)CAPN2 CANPL2Q8WU262
Calpain-5CAPN5E7EV012
Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) (Protein CG36)CAPN9 NCL4O148152
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)CALR CRTCQ6IAT42
Calreticulin (Fragment)CALRK7EJB92
Calreticulin-3 (Calreticulin-2) (Calsperin)CALR3 CRT2Q96L122
Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)]CLSTN1 CS1 KIAA0911Q5SR522
cAMP-dependent protein kinase type I-alpha regulatory subunit (Fragment)PRKAR1AK7EM132
cAMP-regulated phosphoprotein 19ARPP19H3BMD82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)PDE4A DPDE2P278152
Cancer/testis antigen 55 (Tumor antigen BJ-HCC-20)CT55 CXorf48Q8WUE52
Cancer/testis antigen family 45 member A2 (Cancer/testis antigen 45-2) (Cancer/testis antigen 45A2)CT45A2 CT45-2Q5DJT82
CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59)CLIP3 CLIPR59Q96DZ52
CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)CLIP4 RSNL2Q8N3C72
Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105Q9BV092
Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)CHST15 BRAG GALNAC4S6ST KIAA0598Q7LFX52
Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2)CHST4Q8NCG52
Carbohydrate sulfotransferase 6 (EC 2.8.2.-) (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5)CHST6Q9GZX32
Carbonic anhydrase 1 (Fragment)CA1E5RHP72
Carbonic anhydrase 1 (Fragment)CA1E5RJI82
Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase)CA6Q5FBW32
Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase)CA6Q5FC002
Carbonyl reductase family member 4 (EC 1.-.-.-) (3-ketoacyl-[acyl-carrier-protein] reductase beta subunit) (KAR beta subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Quinone reductase CBR4) (Short chain dehydrogenase/reductase family 45C member 1)CBR4 SDR45C1Q8N4T82
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