EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CFIm25) (CPSF 25 kDa subunit) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Pre-mRNA cleavage factor Im 25 kDa subunit)NUDT21 CFIM25 CPSF25 CPSF5Q6NE842
Cleavage and polyadenylation-specificity factor subunit 7 (Fragment)CPSF7F5H0472
Clone CDABP0042 mRNA sequence0Q9H4N92
Clone MM1 product (Fragment)MM1Q162932
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)]CLU APOJ CLI KUB1 AAG4Q5HYC12
CMP-sialic acid transporter (CMP-SA-Tr) (CMP-Sia-Tr) (Solute carrier family 35 member A1)SLC35A1P783822
CMRF35-like molecule 1 (CLM-1) (CD300 antigen-like family member F) (Immune receptor expressed on myeloid cells 1) (IREM-1) (Immunoglobulin superfamily member 13) (IgSF13) (NK inhibitory receptor) (CD antigen CD300f)CD300LF CD300F CLM1 IGSF13 IREM1 NKIR UNQ3105/PRO10111Q8TDQ12
Coagulation factor IX (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]F9Q5FBE12
Coagulation factor VF5A0A0A0MRJ72
Coagulation factor VIIF7F5H8B02
Coatomer protein complex, subunit zeta 1 variant (Fragment)0Q53FU32
Coatomer subunit beta (Beta-coat protein) (Beta-COP)COPB1 COPB MSTP026Q9NTK22
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)COPB2B4DZI82
Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)ARCN1 COPDB4E1X22
Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)COPEA6NKA32
Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)COPZ1 COPZ CGI-120 HSPC181Q549N62
Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)COPZ1 COPZ CGI-120 HSPC181F8VS172
COBW domain-containing protein 3 (Cobalamin synthase W domain-containing protein 3)CBWD3Q5JTY52
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)CFL1 CFLB3KUQ12
Cofilin-2 (Cofilin, muscle isoform)CFL2G3V5P42
Coiled-coil and C2 domain-containing protein 1B (Fragment)CC2D1BH0Y5172
Coiled-coil and C2 domain-containing protein 1B (Fragment)CC2D1BH7C1U32
Coiled-coil and C2 domain-containing protein 2ACC2D2A KIAA1345Q9P2K12
Coiled-coil domain-containing protein 105CCDC105Q8IYK22
Coiled-coil domain-containing protein 110 (Cancer/testis antigen 52) (CT52) (Cancer/testis antigen KM-HN-1)CCDC110 KMHN1Q8TBZ02
Coiled-coil domain-containing protein 121CCDC121Q6ZUS52
Coiled-coil domain-containing protein 127CCDC127Q96BQ52
Coiled-coil domain-containing protein 129CCDC129Q6ZRS42
Coiled-coil domain-containing protein 137CCDC137 cPERP-BQ6PK042
Coiled-coil domain-containing protein 142CCDC142 PSEC0243Q17RM42
Coiled-coil domain-containing protein 146CCDC146 KIAA1505Q8IYE02
Coiled-coil domain-containing protein 15CCDC15Q0P6D62
Coiled-coil domain-containing protein 151CCDC151A5D8V72
Coiled-coil domain-containing protein 153CCDC153Q494R42
Coiled-coil domain-containing protein 159CCDC159P0C7I62
Coiled-coil domain-containing protein 169CCDC169 C13orf38A6NNP52
Coiled-coil domain-containing protein 173CCDC173 C2orf77Q0VFZ62
Coiled-coil domain-containing protein 27CCDC27Q2M2432
Coiled-coil domain-containing protein 39CCDC39Q9UFE42
Coiled-coil domain-containing protein 40CCDC40 KIAA1640Q4G0X92
Coiled-coil domain-containing protein 60CCDC60Q8IWA62
Coiled-coil domain-containing protein 63CCDC63Q8NA472
Coiled-coil domain-containing protein 8CCDC8Q9H0W52
Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A)CCDC85B DIPAQ158342
Coiled-coil domain-containing protein 90B, mitochondrialCCDC90B CUA003 MDS011 MDS025Q9GZT62
Coiled-coil domain-containing protein 97CCDC97Q96F632
Cold agglutinin FS-2 L-chain (Fragment)0A2NB462
Cold inducible RNA binding protein (Cold inducible RNA binding protein, isoform CRA_a) (Testicular tissue protein Li 39)CIRBP hCG_21575Q53XX52
Cold shock domain-containing protein E1CSDE1E9PLT02
Collagen alpha-1(I) chain (Alpha-1 type I collagen)COL1A1Q8N4732
Collagen alpha-1(VI) chainCOL6A1Q9BSA82
Collagen alpha-1(XII) chainCOL12A1 COL12A1LQ5VYK12
Collagen alpha-1(XVI) chainCOL16A1A6NCT72
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin]COL18A1A8MVI42
Collagen alpha-1(XXIII) chainCOL23A1Q86Y222
Collagen alpha-2(IV) chain [Cleaved into: Canstatin]COL4A2Q66K232
Collagen alpha-2(VI) chainCOL6A2Q139102
Collagen alpha-2(VI) chain (Fragment)COL6A2C9JH442
Collagen alpha-2(VI) chain (Fragment)COL6A2H7C0M52
Collagen alpha-3(VI) chain (Fragment)COL6A3I3L3922
Collagen alpha-4(IV) chainCOL4A4P534202
Collagen triple helix repeat-containing protein 1 (Protein NMTC1)CTHRC1 UNQ762/PRO1550Q8IX632
Collagen type V alpha 1COL5A1B2ZZ862
Collagen, type XVIII, alpha 1, isoform CRA_bCOL18A1 hCG_1647196D3DSM52
COMM domain-containing protein 3 (Fragment)COMMD3H0Y4W02
Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13)C1QL3 CTRP13Q5VWW12
Complement C1s subcomponentC1SA0A087X2322
Complement C4-AC4AA0A0G2JPR02
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]C4A CO4 CPAMD2Q5JNX22
Complement component receptor 1-like protein (Complement C4b-binding protein CR-1-like protein)CR1LQ2VPA42
Complement factor B (Fragment)CFBC9JRT32
Complement factor D preproprotein0A6XNE22
Complement factor H-related protein 2CFHR2V9GYE72
Complement factor ICFID6R9Z82
Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1)NDUFAF1 CIA30 CGI-65Q9Y3752
Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)CTGF CCN2 HCS24 IGFBP8Q9UDL62
Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR 1) (CNK homolog protein 1) (CNK1) (hCNK1) (Connector enhancer of KSR-like)CNKSR1 CNK1Q969H42
Constitutive coactivator of PPAR-gamma-like protein 2 (Protein FAM120C) (Tumor antigen BJ-HCC-21)FAM120C CXorf17Q9NX052
Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein)CNTN3 KIAA1496 PANGQ9P2322
Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1)COPRS C17orf79 COPR5Q9NQ922
COP9 signalosome complex subunit 1 (Fragment)GPS1J3QQX02
COP9 signalosome complex subunit 1 (Fragment)GPS1J3QS882
COP9 signalosome complex subunit 3 (Fragment)COPS3K7ELN62
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)COPS3 CSN3B2R6832
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)COPS3 CSN3B4DY812
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)COPS4 CSN4Q9NW312
COP9 signalosome complex subunit 7bCOPS7BJ3KQ342
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)COPS8 CSN8Q53QS92
Copine-8 (Copine VIII)CPNE8Q86VY22
Copine-8 (Copine VIII)CPNE8Q2TB412
Copper homeostasis protein cutC homologCUTC CGI-32Q9NTM92
Coronin0B4DMH32
CoroninCORO1BA0A087WW532
Coronin-1B (Coronin-2)CORO1BB2RD452
Coronin-1C (Coronin-3) (hCRNN4)CORO1C CRN2 CRNN4A7MAP02
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)CORO2B KIAA0925Q9UQ032
Cortactin (Fragment)EMS1Q76MU02
Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 2) (11-DH2) (11-beta-HSD2) (11-beta-hydroxysteroid dehydrogenase type II) (11-HSD type II) (11-beta-HSD type II) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (11-beta-HSD) (Short chain dehydrogenase/reductase family 9C member 3)HSD11B2 HSD11K SDR9C3P803652
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)CRHR1 CRFR CRFR1 CRHRP349982
COX assembly mitochondrial protein 2 homologCMC2 C16orf61 DC13Q9NRP22
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