EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dihydropyridine receptor alpha 2 subunitCACNA2D1Q9UIU02
Dihydropyrimidinase-like 20Q86U752
DIP2C protein (Fragment)DIP2CQ86XV32
Dipeptidase (EC 3.4.13.19)DPEP1Q6I9V12
Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]CTSC CPPIQ53G932
Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl peptidase III)DPP3 hCG_2016942G3V1802
Dipeptidyl peptidase 3 (Fragment)DPP3E9PNX52
Dipeptidyl peptidase 4DPP4F8WBB62
Dipeptidyl peptidase 4DPP4F8WE172
Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8)DPP8 DPRP1 MSTP097 MSTP135 MSTP141Q6V1X12
Disabled homolog 1DAB1O755532
Disco-interacting protein 2 homolog A (DIP2 homolog A)DIP2A C21orf106 DIP2 KIAA0184E7EMA52
Disco-interacting protein 2 homolog B (DIP2 homolog B)DIP2B KIAA1463Q6B0112
Disintegrin and metalloproteinase domain-containing protein 10ADAM10B5MC712
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)ADAM10 KUZ MADMQ926502
Disks large homolog 1DLG1A0A0C4DFT32
Disks large homolog 1 (Fragment)DLG1C9IYP12
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)DLG1A5YKK72
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)DLG1E7EWL72
DKFZP586J0619 proteinDKFZP586J0619 tcag7.531A4D2122
DmX-like protein 1DMXL1F5H2692
DNA (cytosine-5)-methyltransferase 1 (Fragment)DNMT1K7ENW72
DNA cross-link repair 1A protein (SNM1 homolog A) (hSNM1) (hSNM1A)DCLRE1A KIAA0086 SNM1 SNM1AQ6PJP82
DNA damage-binding protein 1 (Fragment)DDB1F5GWI02
DNA dC->dU-editing enzyme APOBEC-3A (A3A) (EC 3.5.4.-) (Phorbolin-1)APOBEC3AP319412
DNA dC->dU-editing enzyme APOBEC-3D (A3D) (EC 3.5.4.-)APOBEC3DQ96AK32
DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (APOBEC-related cytidine deaminase) (APOBEC-related protein) (ARCD) (APOBEC-related protein 9) (ARP-9) (CEM-15) (CEM15) (Deoxycytidine deaminase) (A3G)APOBEC3G MDS019Q9HC162
DNA helicase INO80 (hINO80) (EC 3.6.4.12) (INO80 complex subunit A) (Putative DNA helicase INO80 complex homolog 1)INO80 INO80A INOC1 KIAA1259Q9ULG12
DNA polymerase delta subunit 3 (DNA polymerase delta subunit C) (DNA polymerase delta subunit p66) (DNA polymerase delta subunit p68)POLD3 KIAA0039Q150542
DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)POLE4Q9NR332
DNA polymerase nu (EC 2.7.7.7)POLNQ7Z5Q52
DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)POLG MDP1 POLG1 POLGAP540982
DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)POLQ POLHO754172
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)XPC XPCCQ018312
DNA repair protein complementing XP-G cells (EC 3.1.-.-) (DNA excision repair protein ERCC-5) (Xeroderma pigmentosum group G-complementing protein)ERCC5 ERCM2 XPG XPGCP287152
DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)REV1 REV1LQ9UBZ92
DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)XRCC3O435422
DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]DNA2 DNA2L KIAA0083P515302
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)MCM2 BM28 CCNL1 CDCL1 KIAA0030Q969W72
DNA topoisomerase 2 (EC 5.99.1.3) (Fragment)TOP2BE9PCY52
DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.99.1.2)TOP1MTQ969P62
DNA topoisomerase II, beta isozyme variant (Fragment)0Q59H802
DNA transposase THAP9 (EC 2.7.7.-) (THAP domain-containing protein 9) (hTh9)THAP9Q9H5L62
DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2)RFX7 RFXDC2Q2KHR22
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)PRKDC HYRC HYRC1Q133272
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Fragment)POLR2EA0A087WVN52
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)POLR2HC9JBJ62
DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein homolog)KIN BTCD KIN17O608702
DnaJ (Hsp40) homolog, subfamily C, member 3 (cDNA FLJ77657, highly similar to Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 3 (DNAJC3), mRNA) (cDNA, FLJ93304, Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 3 (DNAJC3),mRNA)DNAJC3 hCG_28703A8KA822
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)DNAJA2 CPR3 HIRIP4O147112
DnaJ homolog subfamily A member 4DNAJA4F5H1702
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)DNAJB1 DNAJ1 HDJ1 HSPF1B4DX522
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080Q542Y92
DnaJ homolog subfamily B member 2 (Fragment)DNAJB2C9JRD22
DnaJ homolog subfamily B member 6 (HHDJ1) (Heat shock protein J2) (HSJ-2) (MRJ) (MSJ-1)DNAJB6 HSJ2 MRJ MSJ1Q6FIC82
DnaJ homolog subfamily C member 7DNAJC7K7EPP72
DnaJ homolog subfamily C member 9 (HDJC9) (DnaJ protein SB73)DNAJC9B2RMW62
DNAJB1 proteinDNAJB1Q6FI512
Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62)DOK1Q997042
Docking protein 6 (Downstream of tyrosine kinase 6)DOK6 DOK5LQ6PKX42
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (Oligosaccharyl transferase 48 kDa subunit)DDOSTA0A0C4DGS12
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1RPN1F8WF322
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Fragment)0Q53EP42
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2)RPN2Q96E212
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Fragment)RPN2F2Z3K52
Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)ADARB1 ADAR2 DRADA2 RED1P785632
Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2) (dsRNA adenosine deaminase B2)ADARB2 ADAR3 RED2Q9NS392
Doublecortin domain-containing protein 1 (Fragment)DCDC1H7C2982
DPCR1 (Diffuse panbronchiolitis critical region protein 1)DPCR1E9PEI62
DPY30 domain-containing protein 2DYDC2Q96IM92
Dual specificity phosphatase DUPD1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase 27)DUPD1 DUSP27Q68J442
Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)DUSP10 MKP5Q9Y6W62
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)DYRK1A DYRK MNB MNBHQ136272
Dynactin subunit 1DCTN1E7EX902
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)DCTN1G5E9H42
Dynactin subunit 2 (Fragment)DCTN2H0YI982
Dynactin subunit 3DCTN3X6RA562
Dynactin subunit 3 (Fragment)DCTN3X6RCK52
Dynamin-1-like protein (Fragment)DNM1LF8VZ522
Dynamin-2 (EC 3.6.5.5)DNM2 DYN2Q9UPH42
Dynein light chain roadblock-type 1DYNLRB1B1AKR62
Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog)DRC7 C16orf50 CCDC135Q8IY822
Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)DYSF FER1L1B1PZ702
DystoninDSTF6QMI72
DystoninDSTE9PHM62
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)DST BP230 BP240 BPAG1 DMH DT KIAA0728Q5TBT22
Dystonin (Fragment)DSTE7ETB92
Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]DAG1Q969J92
E3 ubiquitin-protein ligase Arkadia (EC 2.3.2.27) (RING finger protein 111) (hRNF111) (RING-type E3 ubiquitin transferase Arkadia)RNF111Q6ZNA42
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)STUB1 CHIP PP1131Q9HBT12
E3 ubiquitin-protein ligase CHIP (Fragment)STUB1H3BS862
E3 ubiquitin-protein ligase Hakai (EC 2.3.2.27) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (RING finger protein 188) (RING-type E3 ubiquitin transferase Hakai) (c-Cbl-like protein 1)CBLL1 HAKAI RNF188Q75N032
E3 ubiquitin-protein ligase HECTD1 (Fragment)HECTD1H0YJP02
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)ITCHQ9H4512
E3 ubiquitin-protein ligase MARCH2 (EC 2.3.2.27) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172) (RING-type E3 ubiquitin transferase MARCH2)MARCH2 RNF172 HSPC240Q9P0N82
E3 ubiquitin-protein ligase NEDD4 (Fragment)NEDD4H0Y8X62
E3 ubiquitin-protein ligase NEDD4-likeNEDD4LK7EKL12
E3 ubiquitin-protein ligase Praja-2 (Praja2) (EC 2.3.2.27) (RING finger protein 131) (RING-type E3 ubiquitin transferase Praja-2)PJA2 KIAA0438 RNF131O431642
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)RNF114 ZNF228 ZNF313B4DWY52
E3 ubiquitin-protein ligase RNF169 (EC 2.3.2.27) (RING finger protein 169) (RING-type E3 ubiquitin transferase RNF169)RNF169 KIAA1991Q8NCN42
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