EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170)RNF170Q96K192
E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43)RNF43Q68DV72
E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22)TRIM22 RNF94 STAF50Q8IYM92
E3 ubiquitin-protein ligase TRIM36 (EC 2.3.2.27) (RING finger protein 98) (RING-type E3 ubiquitin transferase TRIM36) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)TRIM36 RBCC728 RNF98Q9NQ862
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)TRIM37 KIAA0898 MUL POB1O949722
E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (RING-type E3 ubiquitin transferase TRIM38) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet)TRIM38 RNF15 RORETO006352
E3 ubiquitin-protein ligase TRIM41 (EC 2.3.2.27) (RING finger-interacting protein with C kinase) (RINCK) (RING-type E3 ubiquitin transferase TRIM41) (Tripartite motif-containing protein 41)TRIM41 RINCKQ8WV442
E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69)TRIM69 RNF36 HSD-34 HSD34Q86WT62
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)TRIP12 KIAA0045 ULFQ14CA32
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)TTC3 DCRR1 RNF105 TPRDP538042
E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)UBR4 KIAA0462 KIAA1307 RBAF600 ZUBR1Q5T4S92
E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283 protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1)ZNRF1 NIN283Q8ND252
Echinoderm microtubule associated protein like 3, isoform CRA_e (Echinoderm microtubule-associated protein-like 3)EML3 hCG_20389B7WPE22
Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1)EML1 EMAP1 EMAPL EMAPL1O004232
Ecotropic viral integration site 2BEVI2BQ9BRW12
Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]ENOX2 COVA1Q162062
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]EDA ED1 EDA2Q928382
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Membrane component chromosome 6 surface marker 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)]ENPP1 M6S1 NPPS PC1 PDNP1Q9UP612
EF-hand calcium-binding domain-containing protein 4A (Calcium release-activated calcium channel regulator 2B) (CRAC channel regulator 2B) (Calcium release-activated channel regulator 2B)CRACR2B EFCAB4AQ8N4Y22
EF-hand calcium-binding domain-containing protein 5 (Fragment)EFCAB5H0Y8432
EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP)EFCAB6 DJBP KIAA1672Q5THR32
EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1)EDIL3 DEL1O438552
EH domain-binding protein 1-like protein 1 (Fragment)EHBP1L1E9PIH62
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)EHD1 PAST PAST1 CDABP0131O146112
eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)GCN1 GCN1L1 KIAA0219Q8N5I52
eIF3L proteinEIF3LQ7Z5X32
Electron transfer flavoprotein subunit alpha, mitochondrialETFAH0YK492
Electron transfer flavoprotein subunit beta (Beta-ETF)ETFB FP585A8K7662
Elongation factor 1-alpha 1EEF1A1A0A087WVQ92
Elongation factor 1-betaEEF1B2F2Z2G22
Elongation factor 1-betaEEF1B2F8WF652
Elongation factor 1-beta (EF-1-beta)EEF1B2 EEF1B EF1BA8K7952
Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)EEF1D EF1DQ969J12
Elongation factor 1-delta (Fragment)EEF1DH0YE722
Elongation factor 1-delta (Fragment)EEF1DE9PL712
Elongation factor 2 (EF-2)EEF2 EF2Q58J862
Elongator complex protein 1IKBKAPF5H2T02
Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein (ES cell-specific 5hmC-binding protein) (Putative peptidase SRAPD1) (EC 3.4.-.-) (SRAP domain-containing protein 1)HMCES C3orf37 DC12 SRAPD1Q96FZ22
Endogenous retrovirus group K member 7 Pol protein (HERV-K(III) Pol protein) (HERV-K102 Pol protein) (HERV-K_1q22 provirus ancestral Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN)]ERVK-7P631352
Endogenous retrovirus group K3 member 1 (HCG2043597, isoform CRA_b) (LOC113386 protein)ERVK3-1 hCG_2043597Q96A102
Endoglin (Osler-Rendu-Weber syndrome 1) (Endoglin (Osler-Rendu-Weber syndrome 1), isoform CRA_b)ENG hCG_18549Q5T9B92
Endonuclease/exonuclease/phosphatase family domain-containing protein 1EEPD1 KIAA1706Q9C0F72
Endoplasmic reticulum resident protein 29HEL-S-107 ERP29 hCG_40139V9HW712
Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075Q6UW142
Endoplasmic reticulum-Golgi intermediate compartment protein 2ERGIC2 ERV41 PTX1 CDA14Q53GY22
Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2)LACTB2 CGI-83Q9Y3922
Endothelial protein C receptor (Activated protein C receptor) (APC receptor) (Endothelial cell protein C receptor) (CD antigen CD201)PROCR EPCRQ142182
Endothelin-2 (ET-2) (Preproendothelin-2) (PPET2)EDN2P208002
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]NEDD9 CASL CASS2Q145112
Enhancer of polycomb homolog 1EPC1Q9H2F52
Envoplakin (Fragment)EVPLK7EQ872
Envoplakin-like proteinEVPLLA8MZ362
EPB41 protein (Protein 4.1)EPB41Q4VB862
EPB41L2 proteinEPB41L2I6L9B12
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)EPHA2 ECKQ8N3Z22
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)EPHB4 HTK MYK1 TYRO11B5A9702
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]EFNA1 EPLG1 LERK1 TNFAIP4P208272
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)EGFR ERBB ERBB1 HER1Q9H2C92
Epidermal growth factor receptor kinase substrate 8-like protein 1EPS8L1K7EKX92
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)EGFL8 C6orf8 NG3 UNQ8752/PRO29920Q999442
Epididymal-specific lipocalin-12LCN12Q6JVE52
Epididymis luminal protein 189 (Putative uncharacterized protein DKFZp686J1372) (Tropomyosin alpha-3 chain)DKFZp686J1372 HEL-189 TPM3Q5VU592
EpiplakinEPPK1A0A087X1U62
Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1Q9UCD02
Epithelial membrane protein 3 (Fragment)EMP3M0QZ662
Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B)ESRP2 RBM35B PP7059Q9H6T02
Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase)EPHX1 EPHX EPOXB2R8N02
EPS8-like 1, isoform CRA_d (Epidermal growth factor receptor kinase substrate 8-like protein 1)EPS8L1 hCG_20264K7EN832
Epsilon-sarcoglycanSGCEE9PEH62
Epsin-3 (Fragment)EPN3D6RBR62
Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)SLC29A1 ENT1B3KQY52
ER membrane protein complex subunit 6 (Transmembrane protein 93)EMC6 TMEM93Q9BV812
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)ERBIN ERBB2IP KIAA1225 LAP2Q1RMD02
ERC protein 2 (Fragment)ERC2H7C4G92
ERGIC and golgi 3 (Fragment)ERGIC3 RP3-477O4.12-015Q5JWS12
ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein) (Endoplasmic reticulum oxidoreductase alpha) (Oxidoreductin-1-L-alpha)ERO1A ERO1L UNQ434/PRO865A8MYW12
Erythroferrone (Complement C1q tumor necrosis factor-related protein 15) (Myonectin)ERFE C1QTNF15 CTRP15 FAM132BQ4G0M12
Ester hydrolase C11orf54C11orf54A0A087WT992
Ester hydrolase C11orf54 (Fragment)C11orf54E9PQS12
Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Protein Ke6) (Ke-6) (Really interesting new gene 2 protein) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239)HSD17B8 FABGL HKE6 RING2 SDR30C1Q925062
Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)PCYT2F5H8B12
Ethylmalonyl-CoA decarboxylase (Fragment)ECHDC1H0Y5L22
Eukaryotic initiation factor 4A-IEIF4A1J3QQP02
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)EIF4A1 DDX2A EIF4AB2R6L82
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3QS692
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3KTB52
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3QLN62
Eukaryotic initiation factor 4A-II (Fragment)EIF4A2E7EMV82
Eukaryotic initiation factor 4A-II (Fragment)EIF4A2J3KSN72
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]EIF4A3 DDX48 KIAA0111Q6IBQ22
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1)ETF1 ERF1 RF1 SUP45L1Q96CG12
Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)EEF1E1 AIMP3 P18Q5THS22
Eukaryotic translation initiation factor 1EIF1K7EM182
Eukaryotic translation initiation factor 2 betaEIF2S2B5BU012
Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta)EIF2S2 EIF2BQ9UJE42
Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF-2-gamma X) (eIF-2gX)EIF2S3 EIF2GB5BTZ42
Eukaryotic translation initiation factor 2 subunit 3 (Fragment)EIF2S3H7BZU12
Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDaEIF2B2Q9BPX42
Eukaryotic translation initiation factor 3 subunit A (Fragment)EIF3AQ6P1R02
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (eIF-3-eta)EIF3B EIF3S9B4DV792
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