EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)IPO7 RANBP7B2R7862
Inactive dual specificity phosphatase 27DUSP27Q5VZP52
Inactive gamma-glutamyltranspeptidase 2GGT2B5MCK82
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)PTK7 CCK4Q8NFA72
Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54)USP54 C10orf29Q70EL12
Inhibin beta B chain (Activin beta-B chain)INHBBQ53T312
INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4)INO80B HMGA1L4 PAPA1 ZNHIT4Q9C0862
Inorganic pyrophosphatasePPA1Q5SQT62
Inorganic pyrophosphatase 2, mitochondrial (Fragment)PPA2H0Y9D82
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)IMPDH1 IMPDHC9J3812
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (Fragment)PPIP5K1H0Y3Y52
Inositol monophosphatase 1 (Fragment)IMPA1E5RG132
Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1)IMPA1 IMPAB4DLN32
Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Kidney-specific protein 32) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase)MIOX ALDRL6 KSP32 RSORQ9UGB72
Inositol-1-monophosphatase (EC 3.1.3.25) (Fragment)IMPA1H0YBL12
Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)ITPKC IP3KCQ96DU72
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)IGF2BP3 IMP3 KOC1 VICKZ3Q63HM02
Insulin-like growth factor type 2 receptor (Insulin-like growth factor type II receptor) (Fragment)IGF2R igf2RA0N9R62
Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)IGFBP4 IBP4A0N9W22
Insulin-like growth factor-binding protein 6 (IBP-6) (IGF-binding protein 6) (IGFBP-6)IGFBP6 IBP6Q144922
Insulinoma-associated protein 2 (Zinc finger protein IA-6)INSM2 IA6 Nbla106Q96T922
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]ITM2B BRI BRI2Q5W0A32
Integral membrane protein 2C (Fragment)ITM2CF5H4I52
Integral membrane protein DGCR2/IDDDGCR2 IDD KIAA0163P981532
Integrator complex subunit 8 (Int8) (Protein kaonashi-1)INTS8 C8orf52Q75QN22
Integrin alpha 2 (Fragment)ITGA2Q71V332
Integrin alpha-3 (Fragment)ITGA3H0YA492
Integrin alpha-3 (Fragment)ITGA3K7EMU32
Integrin alpha-5 (Fragment)ITGA5H0YIV72
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]ITGA6Q9UN032
Integrin alpha-7ITGA7J3KNV42
Integrin alpha-7 (Fragment)ITGA7H0YJ982
Integrin alpha-9 (Fragment)ITGA9H7C2L12
Integrin alpha-V (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]ITGAV MSK8 VNRAQ53SK42
Integrin alpha-V (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]ITGAV MSK8 VNRAE7EWZ62
Integrin beta (Fragment)ITGB4J3QQL22
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)ITGB1 FNRB MDF2 MSK12Q146222
Inter-alpha (Globulin) inhibitor H2, isoform CRA_aITIH2 hCG_25115D3DRR62
Inter-alpha-trypsin inhibitor heavy chain H3ITIH3A0A087WW432
Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]ITIH4 IHRP ITIHL1 PK120 PRO1851E9PGN52
Inter-alpha-trypsin inhibitor heavy chain H5ITIH5C9J2H12
Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)IPCEF1 KIAA0403Q8WWN92
Interferon alpha-21 (IFN-alpha-21) (Interferon alpha-F) (LeIF F)IFNA21P015682
Interferon regulatory factor 5 (IRF-5)IRF5Q135682
Interferon, gamma-inducible protein 16, isoform CRA_a (Interferon, gamma-inducible protein 16, isoform CRA_b)IFI16 hCG_1995098D3DUZ32
Interferon-induced GTP-binding protein Mx1 (Fragment)MX1H9KVD02
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)IFIT5 ISG58 RI58B4DDV12
Interferon-induced transmembrane protein 5 (Bone-restricted interferon-induced transmembrane protein-like protein) (BRIL) (Dispanin subfamily A member 1) (DSPA1)IFITM5A6NNB32
Interferon-inducible protein AIM2 (Absent in melanoma 2)AIM2O148622
Interferon-related developmental regulator 2 (Fragment)IFRD2H7C2Z42
Interleukin 6 signal transducer (Gp130, oncostatin M receptor)IL6STQ17RA02
Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa)ILF2 NF45 PRO3063Q9BWD42
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)IL12RB1 IL12R IL12RBP427012
Interleukin-18IL18B0YJ282
Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma)IL18 IGIF IL1F4Q6WWJ72
Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (CD218 antigen-like family member A) (CDw218a) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (CD antigen CD218a)IL18R1 IL1RRPQ134782
Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25)IL2RAP015892
Interleukin-25 (IL-25) (Interleukin-17E) (IL-17E)IL25 IL17E UNQ3120/PRO10272Q9H2932
Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)IL27RA CRL1 TCCR WSX1 UNQ296/PRO336Q6UWB12
Interleukin-33 (IL-33) (Interleukin-1 family member 11) (IL-1F11) (Nuclear factor from high endothelial venules) (NF-HEV) [Cleaved into: Interleukin-33 (95-270); Interleukin-33 (99-270); Interleukin-33 (109-270)]IL33 C9orf26 IL1F11 NFHEVO957602
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126)IL6RP088872
Intermediate conductance calcium-activated potassium channel protein 4 (Small conductance calcium activated potassium channel type 4 transcript variant 2)KCNN4D1MQ082
Intermediate filament family orphan 1 (Tumor antigen HOM-TES-103)IFFO1 IFFOQ0D2I52
Interphotoreceptor matrix proteoglycan 2 (Interphotoreceptor matrix proteoglycan of 200 kDa) (IPM 200) (Sialoprotein associated with cones and rods proteoglycan) (Spacrcan)IMPG2 IPM200Q9BZV32
Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10)IFT88 TG737 TTC10Q130992
IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)IQCB1 KIAA0036 NPHP5 OK/SW-cl.85Q150512
IQ domain-containing protein CIQCCQ4KMZ12
IQ domain-containing protein GIQCGC9JKX82
IQ motif containing GTPase activating protein 3IQGAP3A2RRC92
Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)ISCA1 HBLD2 GK004Q9BUE62
Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)0Q135842
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)IDH1 PICDQ7Z3V02
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3AH0YMY52
Isoleucine--tRNA ligase, cytoplasmicIARSA0A0A0MSX92
IST1 homolog (Fragment)IST1F5GXM32
IST1 homolog (Fragment)IST1J3KR232
Isthmin-2 (Thrombospondin and AMOP domain-containing isthmin-like protein 1) (Thrombospondin type-1 domain-containing protein 3)ISM2 TAIL1 THSD3 PSEC0137Q6H9L72
ITGA4 proteinITGA4Q68EM92
JAK1 protein (Fragment)JAK1Q6P6692
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)JAKMIP1 GABABRBP JAMIP1 MARLIN1Q96N162
Janus kinase and microtubule-interacting protein 3 (Neuroendocrine long coiled-coil protein 2)JAKMIP3 C10orf14 C10orf39 JAMIP3 NECC2Q5VZ662
JNK1/MAPK8-associated membrane protein (JKAMP) (JNK1-associated membrane protein) (JAMP) (Medulloblastoma antigen MU-MB-50.4)JKAMP C14orf100 JAMP CDA06 HSPC213 HSPC327Q9P0552
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)JUP CTNNG DP3Q150932
Junction plakoglobin (Fragment)JUPC9J8262
Junction-mediating and -regulatory proteinJMYQ8N9B52
Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1)JAML AMICA1 UNQ722/PRO1387Q86YT92
Junctional protein associated with coronary artery disease (JCAD)KIAA1462 JCADQ9P2662
K-glypicanGPC4Q86SV62
Kallikrein 3, (Prostate specific antigen), isoform CRA_k (Prostate-specific antigen) (Prostate-specific antigen variant 1) (Prostate-specific antigen variant 2)KLK3 hCG_22929Q8WTQ82
Kallikrein 3, (Prostate specific antigen), isoform CRA_m (Kallikrein A2) (Prostate specific antigen) (cDNA, FLJ93384, Homo sapiens kallikrein 3, (prostate specific antigen) (KLK3),transcript variant 1, mRNA)KLK3 KLNA2 hCG_22929Q546G32
Kaptin (Actin-associated protein 2E4)KPTNQ9Y6642
KAT8 regulatory NSL complex subunit 1 (MLL1/MLL complex subunit KANSL1) (MSL1 homolog 1) (hMSL1v1) (NSL complex protein NSL1) (Non-specific lethal 1 homolog)KANSL1 CENP-36 KIAA1267 MSL1V1 NSL1Q7Z3B32
KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog)KANSL2 C12orf41 NSL2Q9H9L42
Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 3.6.4.3) (p60 katanin-like 1)KATNAL1Q9BW622
Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein)KLHDC3 PEASQ9BQ902
Kelch domain-containing protein 4KLHDC4Q8TBB52
Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1)KBTBD2 BKLHD1 KIAA1489 CGI-73Q8IY472
Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP)KBTBD8 KIAA1842 TAKRPQ8NFY92
Kelch-like protein 14 (Protein interactor of Torsin-1A) (Printor) (Protein interactor of torsinA)KLHL14 KIAA1384Q9P2G32
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)KLHL20 KLEIPQ9Y2M52
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