EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Leucine-rich repeat-containing protein 47LRRC47 KIAA1185Q9ULN52
Leucine-rich repeat-containing protein 56LRRC56Q8IYG62
Leucine-rich repeat-containing protein 57LRRC57Q8N1T62
Leucine-rich repeat-containing protein 7LRRC7F8WE452
Leucine-rich repeat-containing protein 71LRRC71 C1orf92Q8N4P62
Leukemia-associated protein 7 (Deleted in lymphocytic leukemia 7)DLEU7 LEU7Q6UYE12
Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1)SERPINB1 ELANH2 MNEI PI2Q9UDF82
Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85 antigen-like family member H) (Immunoglobulin-like transcript 1) (ILT-1) (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (CD antigen CD85h)LILRA2 ILT1 LIR7Q8N1492
Leukocyte immunoglobulin-like receptor subfamily A member 3 (CD85 antigen-like family member E) (Immunoglobulin-like transcript 6) (ILT-6) (Leukocyte immunoglobulin-like receptor 4) (LIR-4) (Monocyte inhibitory receptor HM43/HM31) (CD antigen CD85e)LILRA3 ILT6 LIR4Q8N6C82
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)LTK TYK1P293762
Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)LTA4H LTA4Q9UCT72
Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2)LCOR C10orf12 KIAA1795 MLR2Q96JN02
Ligase III, DNA, ATP-dependent (Fragment)LIG3C4B7Q32
LIM and senescent cell antigen-like-containing domain protein 1 (Fragment)LIMS1A0A0M3HER12
LIM domain and actin-binding protein 1LIMA1F8VS072
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)LIMK2P536712
LIM domain only protein 7LMO7E9PMS62
LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein)LDB3 KIAA0613 ZASPO751122
LIM/homeobox protein Lhx5 (LIM homeobox protein 5)LHX5Q9H2C12
Limbic system-associated membrane protein (Fragment)LSAMPH3BLU22
LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]0O003702
Lipase0A8K2H62
Lipase member H (Fragment)LIPHH7C2X12
Lipase member H (Mutant lipase H)LIPHA2IBA62
Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta)LIPI LPDL PRED5Q6XZB02
Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) (hLDAH)LDAH C2orf43Q9H6V92
Lipolysis-stimulated lipoprotein receptorLSR LISCHE9PHD42
Lipolysis-stimulated lipoprotein receptorLSR LISCHQ9UQL32
Lipopolysaccharide-responsive and beige-like anchor protein (Fragment)LRBAH0YAC62
Liprin-alpha-3PPFIA3R4GN362
Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon)LONP2 LONPQ86WA82
Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)LONP1K7EJE82
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)ACADLP283302
LONP1 protein (Fragment)LONP1A4VCH62
Low affinity immunoglobulin gamma Fc region receptor II-c (IgG Fc receptor II-c) (CDw32) (Fc-gamma RII-c) (Fc-gamma-RIIc) (FcRII-c) (CD antigen CD32)FCGR2C CD32 FCG2 IGFR2P319952
Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3) (Solute carrier family 5 member 4)SLC5A4 SAAT1 SGLT2Q9NY912
Low molecular weight phosphotyrosine protein phosphataseACP1F2Z2Q92
Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1)ACP1B5MCC72
Low-density lipoprotein receptor-related protein 11 (LRP-11)LRP11Q86VZ42
LRP2-binding protein (Megalin-binding protein) (MegBP)LRP2BP KIAA1325Q9P2M12
LSR protein (Fragment)LSRQ9BWS22
LUC7-like (S. cerevisiae) (LUC7-like (S. cerevisiae), isoform CRA_f) (Putative RNA-binding protein Luc7-like 1)LUC7L hCG_22425 LA16c-OS12.1-007A8MYV22
Lupus La protein (Fragment)SSBE7ERC42
Ly-6/neurotoxin-like protein 1 (Secreted Ly-6/uPAR domain-containing protein 2) (Secreted Ly-6/uPAR-related protein 2) (SLURP-2)LYNX1 SLURP2Q9BZG92
Lymphocyte activation gene 3 protein (LAG-3) (Protein FDC) (CD antigen CD223)LAG3 FDCQ7Z6432
Lymphocyte antigen 6H (Ly-6H)LY6HO947722
Lymphoid specific helicase variant9HELLSQ6I7N82
Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein]LRMP JAW1Q129122
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)KDM2A CXXC8 FBL7 FBXL11 JHDM1A KIAA1004Q9Y2K72
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)PHF2 CENP-35 KIAA0662O751512
LysM and putative peptidoglycan-binding domain-containing protein 3LYSMD3Q7Z3D42
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)LPAR1 EDG2 LPA1B4DK362
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)LPAR1 EDG2 LPA1P783512
Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lyso-PA acyltransferase) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2)MBOAT2 OACT2Q6ZWT72
Lysophospholipid acyltransferase 7 (Fragment)MBOAT7A9C4B82
Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase)LIPAQ53H212
Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP)PRCP PCPB5BU342
Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)SCARB2 CD36L2 LIMP2 LIMPIIQ53Y632
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)LAMP1B4DWL32
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)LAMP1Q9BRD22
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)LAMP2Q9UD932
Lysozyme g-like protein 2 (EC 3.2.1.-)LYG2 LYGHQ86SG72
Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)LOXL2Q9BW702
M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)CDC25CP303072
MACF1 protein (Fragment)MACF1Q96IQ12
Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2)MARCO SCARA2Q9UEW32
Macrophage-capping protein (Actin regulatory protein CAP-G)CAPG AFCP MCPQ53SA72
Macrophage-capping protein (Fragment)CAPGE7ENU92
Macrophage-stimulating protein receptorMST1RA0A087WZG22
MAGUK p55 subfamily member 5MPP5Q7Z6312
MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1)MPP6 VAM1A4D1572
Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4)MFSD4A MFSD4 UNQ3064/PRO9894Q8N4682
Major histocompatibility complex, class I, EHLA-EQ2L6I52
Major vault protein (Fragment)MVPH3BNF62
Major vault protein (MVP) (Lung resistance-related protein)MVP LRPQ9BQT12
Malate dehydrogenase, cytoplasmicMDH1B9A0412
Malate dehydrogenase, cytoplasmicMDH1B8ZZ512
Maleylacetoacetate isomeraseGSTZ1G3V3B92
MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)MDGA1 MAMDC3Q8NFP42
MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1)MDGA2 MAMDC1 UNQ8188/PRO23197Q7Z5532
MAN2A1 proteinMAN2A1Q49A692
Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha)GMPPAQ9NWC32
MAP1B protein (Fragment)MAP1BQ6PJD32
MAPRE1 protein (Fragment)MAPRE1A2VCR02
MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS)MARCKSL1 MLP MRPQ6NXS52
Mastermind-like protein 1 (Mam-1)MAML1 KIAA0200Q925852
Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45)MEPEQ9NQ762
Matrix metalloproteinase 1 (Fragment)0Q9UHK52
Matrix metalloproteinase 15 (Membrane-inserted)0Q7KZY02
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)MMP14Q6GSF32
Matrix metalloproteinase-28 (MMP-28) (EC 3.4.24.-) (Epilysin)MMP28 MMP25 UNQ1893/PRO4339Q9H2392
Matrix remodeling-associated protein 8 (Limitrin)MXRA8B3KTR62
MAX gene-associated protein (MAX dimerization protein 5)MGA KIAA0518 MAD5Q8IWI92
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)MED20 TRFPB4DE082
MEF2D/DAZAP1 fusion protein (Fragment)DAZAP1Q5IRM72
Meiosis-specific nuclear structural protein 1MNS1Q8NEH62
Mel transforming oncogene variant (Fragment)0Q59EP42
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)MC1R MSHRQ66K382
Melanoma antigen family D, 2, isoform CRA_d (Melanoma-associated antigen D2)MAGED2 hCG_18665Q5H9072
Melanoma-associated antigen B1 (Cancer/testis antigen 3.1) (CT3.1) (DSS-AHC critical interval MAGE superfamily 10) (DAM10) (MAGE-B1 antigen) (MAGE-XP antigen)MAGEB1 MAGEL1 MAGEXPP433662
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