EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ovarian cancer G-protein coupled receptor 1 (OGR-1) (G-protein coupled receptor 68) (GPR12A) (Sphingosylphosphorylcholine receptor)GPR68 OGR1Q157432
Oviduct-specific glycoprotein (Estrogen-dependent oviduct protein) (Mucin-9) (Oviductal glycoprotein) (Oviductin)OVGP1 MUC9 OGPQ128892
Oxidoreductase HTATIP2HTATIP2E9PI872
Oxidoreductase NAD-binding domain-containing protein 1OXNAD1U3KQU82
Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-)OXNAD1Q96HP42
Oxygen-regulated protein 1 (Retinitis pigmentosa 1 protein) (Retinitis pigmentosa RP1 protein)RP1 ORP1P567152
Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6)OSBPL6 ORP6Q9BZF32
Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7)OSBPL7 ORP7Q9BZF22
P antigen family member 5 (PAGE-5) (Cancer/testis antigen 16.1) (CT16.1) (G antigen family E member 1) (Prostate-associated gene 5 protein)PAGE5 GAGEE1Q96GU12
p-glycoprotein 1 (Fragment)ABCB1Q6TBL42
P2Y purinoceptor 11 (P2Y11)P2RY11Q96G912
P2Y purinoceptor 8 (P2Y8)P2RY8Q86VZ12
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)SIN3B KIAA0700O751822
Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375)ZDHHC5 KIAA1748 ZNF375Q9H9232
Pancreas transcription factor 1 subunit alpha (Class A basic helix-loop-helix protein 29) (bHLHa29) (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA-binding subunit of transcription factor PTF1) (PTF1-p48)PTF1A BHLHA29 PTF1P48Q7RTS32
Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)AMY2AB9EJG12
Pannexin-1PANX1 MRS1 UNQ2529/PRO6028O759682
Pannexin-3PANX3Q96QZ02
Paralemmin-2PALM2Q8IXS62
Paraneoplastic antigen-like protein 6APNMA6A PNMA6CP0CW242
Paraspeckle component 1 (Paraspeckle protein 1)PSPC1 PSP1Q8WXE82
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)PTH1R PTHR PTHR1Q034312
PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)PASK KIAA0135Q96RG22
Paternally-expressed gene 3 protein (Zinc finger and SCAN domain-containing protein 24)PEG3 KIAA0287 ZSCAN24Q9GZU22
PaxillinPXNF5GZ782
Paxillin (Fragment)PXNF8W0G02
PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP)PARPBP C12orf48 PARIQ9NWS12
PDZ domain-containing protein GIPC1 (Fragment)GIPC1K7EM112
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)GIPC1 C19orf3 GIPC RGS19IP1Q9BTC92
PDZ domain-containing protein GIPC3GIPC3 C19orf64Q8TF642
Pentatricopeptide repeat-containing protein 2, mitochondrialPTCD2Q8WV602
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)PTX3 TNFAIP5 TSG14Q38M822
Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase)PDF PDF1AQ9HBH12
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (Fragment)PIN1K7EN452
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)0B4DM822
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)0A8K2Q62
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Fragment)PPIHH0YEL52
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Fragment)PPIEE9PKY52
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]PPIA CYPAQ3KQW32
Peptidyl-prolyl cis-trans isomerase A-like 4C (PPIase A-like 4C) (EC 5.2.1.8)PPIAL4CA0A0B4J2A22
Peptidyl-prolyl cis-trans isomerase A-like 4G (PPIase A-like 4G) (EC 5.2.1.8) (Peptidylprolyl cis-trans isomerase A-like 4)PPIAL4GP0DN372
Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)PPIB CYPBA8K5342
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)FKBP3 FKBP25Q143172
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]FKBP4 FKBP52Q9UCV72
Peptidylprolyl isomerase (EC 5.2.1.8)0B7Z6M02
Peptidylprolyl isomerase (EC 5.2.1.8)0B7Z8G22
Perilipin-1 (Lipid droplet-associated protein)PLIN1 PERI PLINO602402
Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17)PLIN3 M6PRBP1 TIP47Q9UP922
Period circadian protein homolog 3 (hPER3) (Cell growth-inhibiting gene 13 protein) (Circadian clock protein PERIOD 3)PER3 GIG13P566452
Peripheral-type benzodiazepine receptor (Fragment)PBRO760682
Peripherin-2 (Retinal degeneration slow protein) (Tetraspanin-22) (Tspan-22)PRPH2 PRPH RDS TSPAN22P239422
Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1)PXDNL VPO2A1KZ922
Peroxiredoxin 3 isoform a (Fragment)0A4UCS52
Peroxiredoxin-1 (EC 1.11.1.15) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2)PRDX1 PAGA PAGB TDPX2P357032
Peroxiredoxin-1 (Fragment)PRDX1A0A0A0MSI02
Peroxiredoxin-2 (EC 1.11.1.15) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1)PRDX2 NKEFB TDPX1A8K0C02
Peroxiredoxin-4 (EC 1.11.1.15) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372)PRDX4Q6FHT32
Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) (Thioredoxin reductase)PRDX5 ACR1 SBBI10Q9UKX42
Peroxisomal biogenesis factor 19PEX19E9PS712
Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7)NUDT7P0C0242
Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha)PEX11A PEX11O751922
Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]HSD17B4 EDH17B4 SDR8C1F5HE572
Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1)PEX6 PXAAA1Q136082
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)PPARG NR1C3P372312
PFKM protein (Phosphofructokinase) (EC 2.7.1.11)PFKMQ7KYX92
PGRMC1 protein (Progesterone receptor membrane component 1) (Progesterone receptor membrane component 1, isoform CRA_a) (cDNA, FLJ94602, Homo sapiens progesterone receptor membrane component 1 (PGRMC1),mRNA)PGRMC1 hCG_23188Q6IB112
PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein)PSD4 EFA6B TICQ8NDX12
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)PHLPP2 KIAA0931 PHLPPLQ6ZVD82
PHD and RING finger domain-containing protein 1PHRF1F8WEF52
PHD finger protein 13 (Survival time-associated PHD finger protein in ovarian cancer 1) (SPOC1)PHF13Q86YI82
PHD finger protein 14PHF14 KIAA0783O948802
PHD finger protein 19 (Polycomb-like protein 3) (hPCL3)PHF19 PCL3Q5T6S32
PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP)PHF20 C20orf104 GLEA2 HCA58 NZF TZPQ9BVI02
Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)FARSB FARSLB FRSB HSPC173Q4ZFX12
Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)FARS2 FARS1 HSPC320O953632
Phosducin-like protein (PHLP)PDCL PHLOP1 PhLP1Q133712
Phosphatidylcholine translocator ABCB4 (Fragment)ABCB4E7EQI12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Fragment)PIK3CBH0Y8712
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)PIP4K2A PIP5K2 PIP5K2AQ5VUX32
Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)PTPRQQ9UMZ32
Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]PISDQ9UG562
Phosphodiesterase (EC 3.1.4.-)PDE5A hCG_38154G5E9C52
Phosphoglucomutase 1 (EC 5.4.2.2) (Fragment)PGM1Q9H1D22
Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)PGK1 PGKA MIG10 OK/SW-cl.110Q5J7W12
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4) (Fragment)PGAM1 HEL-S-35 hCG_2015269 hCG_25778Q6FHU22
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4) (Fragment)0Q53G352
Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1)PIK3AP1 BCAPQ6ZUJ82
Phosphoinositide phospholipase C (EC 3.1.4.11) (Fragment)PLCB1H0YCJ22
Phospholemman (FXYD domain-containing ion transport regulator 1)FXYD1 PLMO001682
Phospholipase A-2-activating protein (Fragment)PLAAH0YBW42
Phospholipase D4 (PLD 4) (EC 3.1.4.4) (Choline phosphatase 4) (Phosphatidylcholine-hydrolyzing phospholipase D4)PLD4 C14orf175 UNQ2488/PRO5775Q96BZ42
Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1)DDHD1 KIAA1705Q8NEL92
Phospholipid scramblasehCG_1987383D3DTP72
Phospholipid scramblase (Fragment)PLSCR1H7C5I52
Phospholipid scramblase (Fragment)PLSCR3I3L1612
Phospholipid scramblase (Fragment)PLSCR3I3NI292
Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b)PLSCR1B4DTE82
Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b)PLSCR1B2R8H82
Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3)PLSCR3Q567U02
Phospholipid transfer protein (Lipid transfer protein II)PLTPA8K0062
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