EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Prefoldin subunit 5 (Fragment)PFDN5H3BPF62
Pregnancy-specific beta-1-glycoprotein 8 (PS-beta-G-8) (PSBG-8) (Pregnancy-specific glycoprotein 8)PSG8Q9UQ742
PRELI domain-containing protein 2PRELID2Q8N9452
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]PSEN1 AD3 PS1 PSNL1Q157192
PRKR-interacting protein 1PRKRIP1Q9H8752
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]NRG1 GGF HGL HRGA NDF SMDFQ022972
Pro-neuregulin-2, membrane-bound isoform (Pro-NRG2) [Cleaved into: Neuregulin-2 (NRG-2) (Divergent of neuregulin-1) (DON-1) (Neural- and thymus-derived activator for ERBB kinases) (NTAK)]NRG2 NTAKO145112
PRO19750Q9UHS82
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120)NOP2 NOL1 NSUN1Q3KQS42
Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)RARS2 RARSLQ5T1602
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72)DDX17B1AHM02
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)DDX5 G17P1 HELR HLR1B5BU212
Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35)DHX35 C20orf15 DDX35Q9H5Z12
Probable cationic amino acid transporter (Solute carrier family 7 member 14)SLC7A14 KIAA1613Q8TBB62
Probable E3 ubiquitin-protein ligase HERC6 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 6) (HECT-type E3 ubiquitin transferase HERC6)HERC6Q8IVU32
Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)MKRN3 D15S9 RNF63 ZNF127Q130642
Probable E3 ubiquitin-protein ligase TRIML1 (EC 2.3.2.27) (RING finger protein 209) (RING-type E3 ubiquitin transferase TRIML1) (Tripartite motif family-like protein 1)TRIML1 RNF209Q8N9V22
Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10)GPR149 PGR10Q86SP62
Probable G-protein coupled receptor 52GPR52Q9Y2T52
Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)ZDHHC14Q8IZN32
Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4) (P4-ATPase flippase complex alpha subunit ATP8B4)ATP8B4 KIAA1939Q8TF622
Probable phospholipid-transporting ATPase VB (EC 3.6.3.1) (ATPase class V type 10B) (P4-ATPase flippase complex alpha subunit ATP10B)ATP10B ATPVB KIAA0715O948232
Probable serine carboxypeptidase CPVL (Fragment)CPVLH7C2182
Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2)TTLL2 C6orf104Q9BWV72
Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein)UTP11 UTP11L CGI-94 HDCMB12PQ9Y3A22
Procollagen C-endopeptidase enhancerPCOLCE tcag7.602A4D2D22
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I variant (Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I, isoform CRA_a) (Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I, isoform CRA_b) (Fragment)P4HA1 hCG_19276Q5VSQ62
Profilaggrin (Fragment)FLGQ152062
Profilin0B4DNH12
Programmed cell death 6 variant (Fragment)0Q53FC32
Programmed cell death 6-interacting proteinPDCD6IPF8WBR82
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)PDCD6IP AIP1 ALIX KIAA1375Q9BX862
Programmed cell death ligand 20A4GW212
Programmed cell death protein 10 (Fragment)PDCD10C9J5C32
Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8)PDCD2 RP8 ZMYND7Q163422
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)PDCD6 ALG2Q5TZS02
Programmed cell death protein 7 (ES18) (hES18)PDCD7Q8N8D12
Proliferating cell nuclear antigenPCNAQ6FI352
Proline-, glutamic acid- and leucine-rich protein 1 (Fragment)PELP1I3L1P42
Proline-rich protein 15-like protein (Protein ATAD4)PRR15L ATAD4Q9BU682
Proline-rich protein 27PRR27 C4orf40Q6MZM92
Proline-rich protein 31PRR31 C9orf141Q5SQ132
Proline-rich protein 36PRR36Q9H6K52
Proline-rich transmembrane protein 3PRRT3 UNQ5823/PRO19642Q5FWE32
Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP)PSTPIP1 CD2BP1O435862
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)P4HA1 P4HAQ150832
Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)PREP PEPQ8N6D42
ProperdinCFPE9PAQ12
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9)PCSK9 NARC1 PSEC0052C0JYY92
Prosalusin (Torsin family 2 member A) (Torsin-2A) [Cleaved into: Salusin-alpha; Salusin-beta]TOR2A HEMBA1005096 PSEC0218Q8N2E62
Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)]PSAP GLBA SAP1P785382
Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)PTGDR2 CRTH2 DL1R GPR44Q9Y5Y42
Prostaglandin E synthase 2 (Prostaglandin E synthase 2, isoform CRA_c)PTGES2 hCG_1785478A6NHH02
Prostaglandin E synthase 3 (cDNA FLJ59832, moderately similar to Prostaglandin E synthase 3 (EC 5.3.99.3))PTGES3B4DDC62
Prostaglandin E synthase 3 (Cytosolic), isoform CRA_c (cDNA FLJ40895 fis, clone UTERU2002294, highly similar to Prostaglandin E synthase 3 (EC 5.3.99.3))PTGES3 hCG_2016483B3KUY22
Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315)PTGFRN CD9P1 EWIF FPRP KIAA1436Q5VVU92
Prostaglandin reductase 2PTGR2G3V2R92
Prostaglandin reductase 3 (PRG-3) (EC 1.3.1.48) (Zinc-binding alcohol dehydrogenase domain-containing protein 2)ZADH2 PTGR3Q8N4Q02
Prostaglandin-H2 D-isomerase (Fragment)PTGDSQ5SQ112
Prostate stem cell antigenPSCAH0YAA62
Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]ACPPQ5FBY02
Protachykinin-1 (PPT) [Cleaved into: Substance P; Neurokinin A (NKA) (Neuromedin L) (Substance K); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide]TAC1 NKA NKNA TAC2P203662
Protease serine 2 preproprotein (Trypsin-2)PRSS2A6XMV92
Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa) (hPAP21)PRADC1 C2orf7 PAP21 UNQ833/PRO1760Q9BSG02
Proteasomal ubiquitin receptor ADRM1ADRM1A0A087WX592
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13, isoform CRA_d (cDNA FLJ53046, highly similar to 26S proteasome non-ATPase regulatory subunit 13)PSMD13 hCG_37689B4DJ662
Proteasome 26S non-ATPase subunit 13 isoform 1 variant (Fragment)0Q53GN62
Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha)PSME1 IFI5111A6NJG92
Proteasome activator complex subunit 2PSME2A0A087X1Z32
Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)PSME3Q9BQD92
Proteasome endopeptidase complex (EC 3.4.25.1)DKFZp686D09174 PSMA2 hCG_19883Q6MZI62
Proteasome endopeptidase complex (EC 3.4.25.1) (Fragment)PSMA4H0YKS02
Proteasome subunit alpha type (EC 3.4.25.1)PSMA2 hCG_19883A0A024RA522
Proteasome subunit alpha type (EC 3.4.25.1) (Fragment)PSMA4H0YMA12
Proteasome subunit alpha type-4 (EC 3.4.25.1) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)PSMA4 HC9 PSC9Q567Q52
Proteasome subunit alpha type-5 (EC 3.4.25.1) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)PSMA5B2R8F62
Proteasome subunit alpha type-6PSMA6G3V2S72
Proteasome subunit alpha type-6 (EC 3.4.25.1) (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)PSMA6 PROS27B4DXJ92
Proteasome subunit alpha type-6 (EC 3.4.25.1) (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)PSMA6 PROS27B2R7J92
Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit RC6-1) (Proteasome subunit XAPC7)PSMA7 HSPCB2R5152
Proteasome subunit beta type-11 (EC 3.4.25.1) (Proteasome subunit beta-5t)PSMB11A5LHX32
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)PSMB5 LMPX MB1 XE9PAV22
Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)PSMB9 LMP2 PSMB6i RING12Q5JNW42
Protein AAR2 homologAAR2A2A2Q92
Protein ABHD16AABHD16AF2Z3G62
Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8)ABHD8Q96I132
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)MLLT3 AF9 YEATS3P425682
Protein angel homolog 1ANGEL1 KIAA0759Q9UNK92
Protein arginine methyltransferase 1 isoform 4HRMT1L2Q5U8W92
Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4)PRMT1 HMT2 HRMT1L2 IR1B4G5E9B62
Protein arginine N-methyltransferase 1 (Fragment)PRMT1H0YDE42
Protein arginine N-methyltransferase 1 (Fragment)PRMT1E9PNR92
Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]PRMT5 HRMT1L5 IBP72 JBP1 SKB1Q9UKH12
Protein arginine N-methyltransferase 5 (Fragment)PRMT5H0YJX62
Protein arginine N-methyltransferase 5 (Fragment)PRMT5G3V2L62
Protein arginine N-methyltransferase 5 (Fragment)PRMT5H0YJD32
Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6)PRMT6 HRMT1L6Q96LA82
Protein ARMCX6ARMCX6Q7L4S72
Protein BEX1 (Brain-expressed X-linked protein 1)BEX1Q9HBH72
Protein broad-minded (TBC1 domain family member 32)TBC1D32 BROMI C6orf170 C6orf171Q96NH32
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