EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein CASC1 (Cancer susceptibility candidate gene 1 protein) (Lung adenoma susceptibility 1-like protein) (Protein phosphatase 1 regulatory subunit 54)CASC1 LAS1 PPP1R54Q6TDU72
Protein CASPCUX1 CUTL1Q139482
Protein CC2D2BCC2D2B C10orf130 C10orf131A6NCD42
Protein CDV3 homolog (Fragment)CDV3H0Y8K32
Protein cornichon homolog 4CNIH4A6NLH62
Protein DBF4 homolog B (Activator of S phase kinase-like protein 1) (ASK-like protein 1) (Chiffon homolog B) (Dbf4-related factor 1)DBF4B ASKL1 DRF1Q8NFT62
Protein DENND6A (DENN domain-containing protein 6A)DENND6A FAM116AQ8IWF62
Protein diaphanous homolog 1DIAPH1H9KV282
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)P4HB ERBA2L PDI PDIA1 PO4DBQ152052
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)PDIA3 ERP57 ERP60 GRP58Q8IYF82
Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)PDIA6 ERP5 P5 TXNDC7B5MCQ52
Protein disulfide-isomerase-like protein of the testisPDILTQ8N8072
Protein DJ-1 (DJ-1) (Oncogene DJ1) (Parkinson disease protein 7) (Parkinsonism-associated deglycase) (Protein deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.124)PARK7O148052
Protein downstream neighbor of Son (B17)DONSON C21orf60Q9NYP32
Protein EFR3 homolog A (Protein EFR3-like)EFR3A KIAA0143Q2VPK22
Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1)LMAN1 ERGIC53 F5F8DQ128952
Protein eva-1 homolog AEVA1AB8ZZF52
Protein eva-1 homolog C (Protein FAM176C) (SUE21)EVA1C C21orf63 C21orf64 FAM176C PRED34 UNQ2504/PRO5993P586582
Protein FAM104AFAM104AQ969W32
Protein FAM117A (C/EBP-induced protein)FAM117AQ9C0732
Protein FAM118BFAM118B FLJ21103 hCG_1811519G3V1792
Protein FAM124BFAM124BQ9H5Z62
Protein FAM126BFAM126BQ8IXS82
Protein FAM131BFAM131B KIAA0773A6NDW32
Protein FAM131CFAM131C C1orf117Q96AQ92
Protein FAM135BFAM135B C8orfK32Q49AJ02
Protein FAM13AFAM13A FAM13A1 KIAA0914O949882
Protein FAM149AFAM149A MST119A5PLN72
Protein FAM160B2 (Retinoic acid-induced protein 16)FAM160B2 RAI16 FP13191Q86V872
Protein FAM161AFAM161AQ3B8202
Protein FAM161BFAM161B C14orf44Q96MY72
Protein FAM162AFAM162AF8W7Q42
Protein FAM172AFAM172A C5orf21Q8WUF82
Protein FAM184AFAM184AA0A087X2A72
Protein FAM184BFAM184B KIAA1276Q9ULE42
Protein FAM193A (Protein IT14)FAM193A C4orf8 RES4-22P783122
Protein FAM193B (Fragment)FAM193BD6RAX92
Protein FAM198B (Expressed in nerve and epithelium during development)FAM198B C4orf18 ENED AD021 UNQ2512/PRO6001Q6UWH42
Protein FAM19A5 (Chemokine-like protein TAFA-5)FAM19A5 TAFA5 UNQ5208/PRO34524Q7Z5A72
Protein FAM220A (STAT3-interacting protein as a repressor)FAM220A C7orf70 SIPARQ7Z4H92
Protein FAM234BFAM234B KIAA1467A2RU672
Protein FAM26FFAM26F C6orf187Q5R3K32
Protein FAM3C (Fragment)FAM3CC9JP352
Protein FAM3C (Interleukin-like EMT inducer)FAM3C ILEI GS3786A8K3R72
Protein FAM65CFAM65C C20orf175Q96MK22
Protein FAM71DFAM71DG3V4K82
Protein FAM71F1 (Protein FAM137A) (Testis development protein NYD-SP18)FAM71F1 FAM137AQ96KD32
Protein FAM78BFAM78BQ5VT402
Protein FAM83D (Spindle protein CHICA)FAM83D C20orf129Q9H4H82
Protein FAM8A1 (Autosomal highly conserved protein)FAM8A1 AHCPQ9UBU62
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)RPGRIP1L FTM KIAA1005 NPHP8Q68CZ12
Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)FEM1B F1AA KIAA0396Q9UK732
Protein fem-1 homolog C (FEM1c) (FEM1-gamma)FEM1C KIAA1785Q96JP02
Protein GPR108 (Lung seven transmembrane receptor 2)GPR108 LUSTR2Q9NPR92
Protein HEATR9 (HEAT repeat-containing protein 9)HEATR9 C17orf66A2RTY32
Protein HGH1 homologHGH1 C8orf30A C8orf30B FAM203A FAM203BP0CB432
Protein Hook homolog 2 (Fragment)HOOK2K7EJA72
Protein IWS1 homolog (Fragment)IWS1B8ZZB62
Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16)JADE3 KIAA0215 PHF16Q926132
Protein Jumonji (Jumonji/ARID domain-containing protein 2)JARID2 JMJQ928332
Protein KIAA2022KIAA2022Q5QGS02
Protein kinase C and casein kinase substrate in neurons protein 1PACSIN1F6U2362
Protein kinase C and casein kinase substrate in neurons protein 3 (Fragment)PACSIN3H0YDM62
Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35) (Transmembrane BAX inhibitor motif-containing protein 2)FAIM2 KIAA0950 LFG LFG2 NMP35 TMBIM2Q9BWQ82
Protein lifeguard 3 (Fragment)TMBIM1C9JAP52
Protein LMBR1L (Limb region 1 protein homolog-like) (Lipocalin-1-interacting membrane receptor) (Lipocalin-interacting membrane receptor)LMBR1L KIAA1174 LIMR UNQ458/PRO783Q6UX012
Protein mago nashi homologMAGOH MAGOHAB1ARP82
Protein MEMO1 (C21orf19-like protein) (Hepatitis C virus NS5A-transactivated protein 7) (HCV NS5A-transactivated protein 7) (Mediator of ErbB2-driven cell motility 1) (Mediator of cell motility 1) (Memo-1)MEMO1 C2orf4 MEMO NS5ATP7 CGI-27B4DLS02
Protein MEMO1 (C21orf19-like protein) (Hepatitis C virus NS5A-transactivated protein 7) (HCV NS5A-transactivated protein 7) (Mediator of ErbB2-driven cell motility 1) (Mediator of cell motility 1) (Memo-1)MEMO1 C2orf4 MEMO NS5ATP7 CGI-27Q5R2V82
Protein MIS12 homologMIS12Q9H0812
Protein MTO1 homolog, mitochondrialMTO1 CGI-02Q9Y2Z22
Protein naked cuticle homolog 2 (Naked-2) (hNkd2)NKD2Q969F22
Protein NDRG2 (Fragment)NDRG2G3V5H82
Protein NLRC5 (Fragment)NLRC5F5H2742
Protein NRDE2 homologNRDE2 C14orf102Q9H7Z32
Protein NYNRIN (NYN domain and retroviral integrase catalytic domain-containing protein) (Protein cousin of GIN1)NYNRIN CGIN1 KIAA1305Q9P2P12
Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196)POMK SGK196Q9H5K32
Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2)POMT2Q9UKY42
Protein O-mannosyl-transferase 2 (Fragment)POMT2H0YJJ42
Protein orai-2 (CAP-binding protein complex-interacting protein 2) (Transmembrane protein 142B)ORAI2 C7orf19 CBCIP2 TMEM142B PP1729Q96SN72
Protein PBDC1PBDC1A6NDF32
Protein PET117 homolog, mitochondrialPET117 UNQ607/PRO1194Q6UWS52
Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)PPP1R15A GADD34O758072
Protein phosphatase 1 regulatory subunit 26PPP1R26 KIAA0649Q5T8A72
Protein phosphatase 1 regulatory subunit 29 (Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2) (Leucine-rich repeat and fibronectin type-III domain-containing protein 6) (Leucine-rich repeat-containing protein 62)ELFN2 KIAA1904 LRRC62 PPP1R29Q5R3F82
Protein phosphatase 1 regulatory subunit 7PPP1R7B5MBZ82
Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA)PPM1E CAMKN KIAA1072 POPX1Q8WY542
Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform (Testicular secretory protein Li 1) (cDNA FLJ78455, highly similar to Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA) (cDNA, FLJ96799, Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA)PPP2R1A hCG_19686A8K7B72
Protein PIMREG (CALM-interactor expressed in thymus and spleen) (PICALM interacting mitotic regulator) (Regulator of chromosome segregation protein 1)PIMREG CATS FAM64A RCS1Q9BSJ62
Protein PRRC2CPRRC2CE7EPN92
Protein PTHB1 (Bardet-Biedl syndrome 9 protein) (Parathyroid hormone-responsive B1 gene protein)BBS9 PTHB1Q3SYG42
Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa)RCC2 KIAA1470 TD60Q9NPV82
Protein RedIKD6RAH12
Protein S100 (S100 calcium-binding protein)S100A1 hCG_15470Q5T7Y62
Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed]S100A11 MLN70 S100CQ5VTK02
Protein S100-A13 (S100 calcium-binding protein A13)S100A13Q52PI92
Protein S100-A7-like 2 (S100 calcium-binding protein A7-like 2)S100A7L2 S100A7BQ5SY682
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTULQ96C692
Protein SETSETA0A0C4DFV92
Protein shisa-5 (Putative NF-kappa-B-activating protein 120) (Scotin)SHISA5 SCOTIN PSEC0133Q8N1142
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