EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein shisa-7 (Protein shisa-6-like)SHISA7A6NL882
Protein shisa-like-2BSHISAL2B FAM159BA6NKW62
Protein SLX4IP (SLX4-interacting protein)SLX4IP C20orf94Q5VYV72
Protein SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5)SMG5 EST1B KIAA1089Q9UPR32
Protein SOGA1 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]SOGA1 C20orf117 KIAA0889 SOGAO949642
Protein spinster homolog 2SPNS2Q8IVW82
Protein SSX2 (Cancer/testis antigen 5.2) (CT5.2) (Synovial sarcoma, X breakpoint 2) (Tumor antigen HOM-MEL-40)SSX2 SSX2A; SSX2BQ163852
Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)SS18 SSXT SYTQ155322
Protein stum homologSTUM C1orf95Q69YW22
Protein TFG (TRK-fused gene protein)TFGG5E9V12
Protein TMED8TMED8 FAM15B L10Q6PL242
Protein TMEPAI (Prostate transmembrane protein androgen induced 1) (Solid tumor-associated 1 protein) (Transmembrane prostate androgen-induced protein)PMEPA1 STAG1 TMEPAIQ969W92
Protein translocation complex beta variant (Fragment)0Q53FA52
Protein transport protein Sec23A (Fragment)SEC23AG3V4V12
Protein transport protein Sec61 subunit alpha isoform 1 (cDNA FLJ59739, highly similar to Protein transport protein Sec61 subunit alpha isoform 1)SEC61A1B4DR612
Protein tweety homolog (Fragment)TTYH3H7C3T62
Protein tweety homolog 1 (hTTY1)TTYH1Q9H3132
Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)PTP4A2 PRL2 PTPCAAX2 BM-008Q152612
Protein tyrosine phosphatase, receptor type, C, isoform CRA_d (Receptor-type tyrosine-protein phosphatase C)PTPRC hCG_1811178A0A0A0MT222
Protein very KIND (v-KIND) (Cerebral protein 9) (KIND domain-containing protein 1) (Kinase non-catalytic C-lobe domain-containing protein 1) (Ras-GEF domain-containing family member 2)KNDC1 C10orf23 KIAA1768 RASGEF2 VKIND hucep-9Q76NI12
Protein Wnt (Fragment)WNT5BF5H7Q62
Protein Wnt-10b (Protein Wnt-12)WNT10B WNT12O007442
Protein Wnt-7aWNT7AO007552
Protein Wnt-9a (Protein Wnt-14)WNT9A WNT14O149042
Protein XRP2RP2Q9NU672
Protein YIF1AYIF1AE9PS112
Protein YIF1A (Fragment)YIF1AE9PIZ02
Protein YIF1BYIF1BK7EPQ72
Protein YIPF4 (Fragment)YIPF4H7C0D52
Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1)ZGRF1 C4orf21Q6ZU112
Protein-glutamate O-methyltransferaseARMT1F5GZY12
Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase H) (TGase H) (Transglutaminase-2) (TGase-2)TGM2Q9UH352
Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77)PCMT1H7BY582
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2PCMTD2 C20orf36Q9NV792
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase)PCMT1Q9NP032
Proteoglycan 3 (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH)PRG3 MBPH UNQ486/PRO1002Q9Y2Y82
Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)PLP2 A4Q32MM82
Proto-oncogene c-RelRELQ048642
Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein]MCF2 DBLP109112
Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Proto-oncogene c-Mos)MOSP005402
Proto-oncogene Wnt-1 (Proto-oncogene Int-1 homolog)WNT1 INT1P046282
Protocadherin 9 (Protocadherin-9)PCDH9 hCG_2026614Q5VT822
Protocadherin beta-2 (PCDH-beta-2)PCDHB2Q9Y5E72
Protocadherin gamma-A1 (PCDH-gamma-A1)PCDHGA1Q9Y5H42
Protocadherin gamma-A12 (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3)PCDHGA12 CDH21 FIB3 KIAA0588 UNQ371/PRO707O603302
Protocadherin gamma-C4 (PCDH-gamma-C4)PCDHGC4Q9Y5F72
Protocadherin-9PCDH9Q9HC562
Proton-coupled amino acid transporter 2SLC36A2E5RJJ52
PrP amyloid (Fragment)PRNPQ164092
Pseudokinase FAM20A (Putative uncharacterized protein FP2747)FP2747 FAM20AQ71MG52
PSMD1 protein (Fragment)PSMD1Q05CW62
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)PNP NPQ151602
Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S)NPEPPS PSAQ9UEM22
Putative 40S ribosomal protein S26-like 1RPS26P11 RPS26L1Q5JNZ52
Putative ankyrin repeat domain-containing protein 31ANKRD31Q8N7Z52
Putative BMP-2-inducible kinase-like proteinBMP2KLQ5H9B92
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial (Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9)CHCHD2P9 C9orf49 CHCHD9Q5T1J52
Putative deoxyribonuclease TATDN1 (EC 3.1.21.-) (Hepatocarcinoma high expression protein)TATDN1 CDA11Q9BY402
Putative G-protein coupled receptorGPCRQ8TDT02
Putative glutathione-specific gamma-glutamylcyclotransferase 2 (Gamma-GCG 2) (EC 2.3.2.-) (Cation transport regulator-like protein 2)CHAC2Q8WUX22
Putative hydroxypyruvate isomerase (Fragment)HYIJ9JIE92
Putative MAPK activating protein0Q7Z4262
Putative methyltransferase C9orf114 (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (SPOUT domain-containing methyltransferase 1)SPOUT1 C9orf114Q5T2802
Putative nascent polypeptide-associated complex subunit alpha-like protein (Alpha-NAC pseudogene 1) (NAC-alpha pseudogene 1)NACAP1 FKSG17Q9BZK32
Putative RNA helicase Ski2wSKI2WO760462
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2)RPAP2 C1orf82Q8IXW52
Putative serpin A13SERPINA13P SERPINA13 UNQ6121/PRO20043Q6UXR42
Putative STAG3-like protein 1 (Stromal antigen 3-like protein 1)STAG3L1P0CL832
Putative transporter SVOPL (SV2-related protein-like) (SVOP-like protein)SVOPLQ8N4342
Putative uncharacterized protein0Q8NCV32
Putative uncharacterized protein (Fragment)0Q59GM22
Putative uncharacterized protein (Fragment)0Q8TBL12
Putative uncharacterized protein (Fragment)0Q96CD82
Putative uncharacterized protein (Fragment)0Q9UJM02
Putative uncharacterized protein (Ribosomal protein L10, isoform CRA_a) (cDNA: FLJ23544 fis, clone LNG08336)RPL10 hCG_2008007Q9GZW22
Putative uncharacterized protein DDEF2 (Fragment)DDEF2Q53RS32
Putative uncharacterized protein DKFZp313J1510 (Fragment)DKFZp313J1510Q69YS12
Putative uncharacterized protein DKFZp434D199 (U5 small nuclear ribonucleoprotein 40 kDa protein) (WD repeat domain 57 (U5 snRNP specific), isoform CRA_b)DKFZp434D199 SNRNP40 WDR57 hCG_20041Q9NSS82
Putative uncharacterized protein DKFZp434F152 (Fragment)DKFZp434F152Q659F82
Putative uncharacterized protein DKFZp564H1664DKFZp564H1664Q659E82
Putative uncharacterized protein DKFZp586I031 (Septin-7)DKFZp586I031 SEPT7Q5JXL72
Putative uncharacterized protein DKFZp686A13234 (Fragment)DKFZp686A13234Q6MZS52
Putative uncharacterized protein DKFZp686A15170 (Fragment)DKFZp686A15170Q68DG42
Putative uncharacterized protein DKFZp686J08125 (Fragment)DKFZp686J08125Q5HYC42
Putative uncharacterized protein DKFZp686K0542 (Fragment)DKFZp686K0542Q5CZA72
Putative uncharacterized protein DKFZp686L11144 (Fragment)DKFZp686L11144Q6N0842
Putative uncharacterized protein DKFZp686O01196DKFZp686O01196Q6N0942
Putative uncharacterized protein DKFZp686O0665DKFZp686O0665Q7Z3342
Putative uncharacterized protein DKFZp761N1814 (Fragment)DKFZp761N1814Q9NSG92
Putative uncharacterized protein DKFZp762K123 (Fragment)DKFZp762K123Q69YP22
Putative uncharacterized protein DKFZp781O2021DKFZp781O2021Q68DU02
Putative uncharacterized protein encoded by CACTIN-AS1 (Cactin antisense RNA 1)CACTIN-AS1 C19orf29-AS1 C19orf29OSQ8N1I82
Putative uncharacterized protein encoded by COL5A1-AS1 (COL5A1 antisense RNA 1) (COL5A1 antisense gene protein 1)COL5A1-AS1 C9orf104Q5SY132
Putative uncharacterized protein encoded by LINC00336LINC00336 C6orf227 NCRNA00336Q6ZUF62
Putative uncharacterized protein encoded by LINC00587LINC00587 C9orf107B1AMM82
Putative uncharacterized protein HSPD1 (Fragment)HSPD1Q53SE22
Putative uncharacterized protein LOC1001290270Q6AWC82
Putative uncharacterized protein LRP2 (Fragment)LRP2Q53TL02
Putative uncharacterized protein MGAT5 (Fragment)MGAT5Q53SZ92
Putative uncharacterized protein PSMD14 (Fragment)PSMD14Q4ZG772
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