EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sarcoma antigen 1 (Cancer/testis antigen 14) (CT14)SAGE1 SAGEQ9NXZ12
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 3.6.3.8) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)ATP2A2 ATP2BB4DF052
SARS proteinSARSQ0VGA52
Scavenger receptor class A member 3 (Cellular stress response gene protein)SCARA3 CSRQ6AZY72
Scavenger receptor class A member 5 (Scavenger receptor hlg)SCARA5 UNQ2938/PRO28700Q6ZMJ22
Scavenger receptor cysteine-rich domain-containing group B protein (Four scavenger receptor cysteine-rich domains-containing protein) (S4D-SRCRB)SSC4D SRCRB4DQ8WTU22
Schlafen family member 11SLFN11Q7Z7L12
SciellinSCELF2Z2X82
SclerostinSOST UNQ2976/PRO7455/PRO7476Q9BQB42
Sclerostin domain-containing protein 1 (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1)SOSTDC1 USAG1 CDA019Q6X4U42
Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1)SFMBT1 RU1Q9UHJ32
SCO-spondinSSPO KIAA2036A2VEC92
Scrapie-responsive protein 1 (Scrapie-responsive gene 1 protein) (ScRG-1)SCRG1 UNQ390/PRO725O757112
Secreted protein, acidic, cysteine-rich (Osteonectin), isoform CRA_aSPARC hCG_39149D3DQH82
Secretory carrier-associated membrane protein (Secretory carrier membrane protein)SCAMP1A0A087WXB02
Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)SCAMP1 SCAMPQ6FG232
Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3)SCAMP3 C1orf3 PROPIN1Q96FR82
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)DVL1O146402
Selectin-like protein0Q5JB402
Selenoprotein H (SelH)SELENOH C11orf31 SELHQ8IZQ52
Semaphorin-3ESEMA3E KIAA0331 SEMAHO150412
Semaphorin-4GSEMA4G KIAA1619Q9NTN92
SEMG1 protein (Fragment)SEMG1A0JLP22
Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)ESPL1 ESP1 KIAA0165Q146742
Septin-10SEPT10Q9HAH62
Septin-11SEPT11Q96SP12
Septin-2 (Fragment)SEPT2C9IY942
Septin-2 (Fragment)SEPT2H7C3102
Septin-2 (Fragment)SEPT2C9JFT12
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)SEPT2 DIFF6 KIAA0158 NEDD5Q96CB02
Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1)SEPT9 KIAA0991 MSFB4DTL92
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)SQSTM1 ORCA OSILQ9BUV72
Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein)SRGN PRG PRG1B2R4L72
SERINC2 protein (Fragment)SERINC2Q96IM82
Serine hydroxymethyltransferase (EC 2.1.2.1)0B4DJQ32
Serine hydroxymethyltransferase (EC 2.1.2.1) (Fragment)SHMT2Q5BJF52
Serine hydroxymethyltransferase, mitochondrialSHMT2G3V2D22
Serine hydroxymethyltransferase, mitochondrial (Fragment)SHMT2G3V5L02
Serine hydroxymethyltransferase, mitochondrial (Fragment)SHMT2G3V2412
Serine hydroxymethyltransferase, mitochondrial (Fragment)SHMT2G3V4W52
Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)SHMT2B7Z9F12
Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3)SPTLC3 C20orf38 SPTLC2LQ9NUV72
Serine protease 23 (EC 3.4.21.-) (Putative secreted protein Zsig13)PRSS23 ZSIG13 UNQ270/PRO307Q6IBI02
Serine protease 38 (EC 3.4.21.-) (Marapsin-2)PRSS38 MPN2A1L4532
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)HTRA1 HTRA PRSS11Q9UNS52
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)SARS SERSB2R6Y92
Serine-rich coiled-coil domain-containing protein 1 (Coiled-coil serine-rich protein 1)CCSER1 FAM190A KIAA1680Q9C0I32
Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog)CCSER2 FAM190B KIAA1128 NPD012Q9H7U12
Serine-threonine kinase receptor-associated protein (Fragment)STRAPH0YH332
Serine/arginine repetitive matrix protein 1 (Fragment)SRRM1M0R0882
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3Q138092
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)SRSF6 SFRS6 SRP55Q9Y3N72
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)SRSF7 SFRS7G5E9M32
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)SRSF9 SFRS9 SRP30CQ52LD12
Serine/arginine-rich-splicing factor 3SRSF3A0A087X2D02
Serine/arginine-rich-splicing factor 7 (Splicing factor, arginine/serine-rich 7, 35kDa, isoform CRA_a)SRSF7 SFRS7 hCG_15878A0A0B4J1Z12
Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)STK17B DRAK2O947682
Serine/threonine-protein kinase 24 (Fragment)STK24H0Y6302
Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)STK26 MASK MST4Q9BXC32
Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine-protein kinase NYD-SPK) (Sugen kinase 396) (SgK396)STK31 SGK396Q9BXU12
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)BRSK1 KIAA1811 SAD1 SADBQ8TDC32
Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12Q8IWQ32
Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)CHEK1 CHK1O147572
Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (HSPK 36) (Never in mitosis A-related kinase 3) (NimA-related protein kinase 3)NEK3P519562
Serine/threonine-protein kinase PAK 1 (Fragment)PAK1H0YCM02
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)ACVRL1 ACVRLK1 ALK1P370232
Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)SGK3 CISK SGKLQ96BR12
Serine/threonine-protein kinase TAO3 (Fragment)TAOK3F5GX962
Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)TLK1 KIAA0137Q9UKI82
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)ULK1 KIAA0722O753852
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)VRK2Q86Y072
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)WNK3 KIAA1566 PRKWNK3Q9BYP72
Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]ERN1 IRE1O754602
Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]ERN2 IRE2Q76MJ52
Serine/threonine-protein phosphatase (EC 3.1.3.16)PPP1CCF8VR822
Serine/threonine-protein phosphatase (EC 3.1.3.16) (Fragment)PPP1CAE9PMD72
Serine/threonine-protein phosphatase (EC 3.1.3.16) (Fragment)PPP2CBE5RFI32
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)PPP2R5DQ151712
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)PPP2R5EQ52LW42
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)PPP2R5EB7ZKK92
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Fragment)PPP2R1AC9J9C12
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)PPP2R1AQ6ICQ32
Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (Phosphotyrosyl phosphatase activator)PTPAA6PVN52
Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (Phosphotyrosyl phosphatase activator)PTPAF6WIT22
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (Fragment)PPP2CBH0YC232
Serine/threonine-protein phosphatase 4 regulatory subunit 3APPP4R3AG3V5Z32
Serine/threonine-protein phosphatase 6 regulatory subunit 3PPP6R3H7BXH22
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)PPP1CA PPP1AP228022
Serine/threonine-protein phosphatase PP1-beta catalytic subunitPPP1CBF8WE712
Serine/threonine-protein phosphatase with EF-hands 2 (PPEF-2) (EC 3.1.3.16)PPEF2O148302
Serotransferrin (Fragment)TFC9JVG02
Serpin B4 (Fragment)SERPINB4H0Y5H92
Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5)SERPINB5 PI5Q8WW892
Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)SERPINB6 PI6 PTIQ59F972
Serpin H1SERPINH1E9PKH22
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14Q9NP882
Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1SERPIND1Q8IVC02
SERPINE1 mRNA binding protein 1, isoform CRA_cSERBP1 hCG_2032021D3DQ692
SERPINE1 mRNA binding protein 1, isoform CRA_dSERBP1 hCG_2032021D3DQ702
Serrate RNA effector molecule homolog (Arsenite-resistance protein 2)SRRT ARS2 ASR2Q8TDQ52
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