EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Serum albuminALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341Q131402
Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)]SAA1P027352
Serum paraoxonase/arylesterase 1PON1F8WF422
Sestrin-2 (EC 1.11.1.15) (Hypoxia-induced gene)SESN2 Hi95 SEST2P580042
Sex hormone-binding globulin (Fragment)SHBGA0A0C4DGN22
SF3B1 protein (Fragment)SF3B1Q32Q202
SH2 domain-containing adapter protein DSHDQ96IW22
SH2 domain-containing protein 2A (SH2 domain-containing adapter protein) (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein)SH2D2A SCAP TSAD VRAPQ9NP312
SH2 domain-containing protein 3C (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1)SH2D3C NSP3 UNQ272/PRO309/PRO34088Q8N5H72
SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS)SH2B2 APSO144922
SH3 domain GRB2-like 1 (SH3-domain GRB2-like 1) (SH3-domain GRB2-like 1, isoform CRA_b) (SH3GL1 protein) (cDNA, FLJ96508, Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA)SH3GL1 hCG_21932Q6FGM02
SH3 domain-binding protein 2 (3BP-2)SH3BP2 3BP2 RES4-23P783142
SH3 domain-containing kinase-binding protein 1 (Fragment)SH3KBP1Q5JPT22
SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein)SGIP1Q9BQI52
SH3KBP1-binding protein 1SHKBP1M0QX422
Short stature homeobox protein (Pseudoautosomal homeobox-containing osteogenic protein) (Short stature homeobox-containing protein)SHOX PHOGO152662
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)TRPC1 TRP1P489952
SHUJUN-20Q7Z5Z22
Sialic acid synthase (Fragment)NANSQ5TBR02
SICAM-1 (Fragment)sICAM-1Q999302
Sickle tail protein homologKIAA1217 SKTA6NLF32
Signal peptidase complex subunit 3 homolog (S. cerevisiae), isoform CRA_aSPCS3 hCG_1787020D3DP462
Signal peptide, CUB and EGF-like domain-containing protein 1SCUBE1Q8IWY42
Signal recognition particle 14 kDa proteinSRP14H0YLA22
Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein)SRP14Q6B0K52
Signal recognition particle 9 kDa protein (SRP9)SRP9Q6NVX02
Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)SRP68Q8NCJ42
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)STAT1Q9UDL52
Signal transducer and activator of transcription 4STAT4Q147652
Signal transducing adapter molecule 1 (Fragment)STAMA6NMU32
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)SIPA1L2 KIAA1389Q9P2F82
Similar to collagen, type VI, alpha 3 (Fragment)0Q8N4Z12
Similar to filamin C, gamma (Actin binding protein 280) (Fragment)0Q86TQ32
Similar to intersectin 2 (Fragment)0Q8IWI52
Similar to plastin 3 (T isoform) (Fragment)0Q96HI12
Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa)SSNA1 NA14O438052
SKI family transcriptional corepressor 2 (Functional Smad-suppressing element on chromosome 18) (Fussel-18) (LBX1 corepressor 1-like protein) (Ladybird homeobox corepressor 1-like protein)SKOR2 CORL2 FUSSEL18Q2VWA42
SLAM family member 8 (B-lymphocyte activator macrophage expressed) (BCM-like membrane protein) (CD antigen CD353)SLAMF8 BLAMEQ9P0V82
SLC12A1 protein (Solute carrier family 12 member 1)SLC12A1Q8IUN52
SLC35A4 upstream open reading frame proteinSLC35A4L0R6Q12
SLIT-ROBO Rho GTPase activating protein 2 (SLIT-ROBO Rho GTPase-activating protein 2)SRGAP2A2RUF32
Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)KCNN2Q9H2S12
Small EDRK-rich factor 2 (Gastric cancer-related protein VRG107) (Protein 4F5-related) (4F5rel) (h4F5rel)SERF2 FAM2CP841012
Small integral membrane protein 19SMIM19 C8orf40Q96E162
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)SNRPEP085782
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)SNRPF PBSCFQ6IBQ12
Small nuclear ribonucleoprotein GSNRPGF5H0132
Small nuclear ribonucleoprotein polypeptide A' variant (Fragment)0Q53G212
Small nuclear ribonucleoprotein polypeptide C variant (Fragment)0Q53G332
Small nuclear ribonucleoprotein Sm D1SNRPD1Q7Z5A32
Small nuclear ribonucleoprotein-associated protein N (Fragment)SNRPNJ3QLE52
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)SNRPN HCERN3 SMNB3KVR12
Small proline-rich protein 3 (Fragment)SPRR3B1AN482
SMARCD2 protein (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2)SMARCD2B9EGA32
SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1)SLF1 ANKRD32 BRCTD1Q9BQI62
SMC5-SMC6 complex localization factor protein 2 (Smc5/6 localization factor 1)SLF2 C10orf6 FAM178AQ8IX212
SNRNP200 protein (Fragment)SNRNP200Q7L5W42
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)SLC4A7 BT NBC2 NBC2B NBC3 NBCn1 SBC2 SLC4A6Q9HC882
Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)SCLT1 SAP1Q96NL62
Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1)SCN1A NAC1 SCN1P354982
Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2)SCN2A NAC2 SCN2A1 SCN2A2Q992502
Sodium leak channel non-selective protein (CanIon) (Voltage gated channel-like protein 1)NALCN VGCNL1Q8IZF02
Sodium- and chloride-dependent betaine transporter (BGT-1) (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12)SLC6A12P480652
Sodium- and chloride-dependent GABA transporter 1 (Fragment)SLC6A1C9J5P82
Sodium-ascorbic acid transporter 20A0MSJ52
Sodium-coupled neutral amino acid transporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)SLC38A2 ATA2 KIAA1382 SAT2 SNAT2Q9P2G52
Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)MFSD4B KIAA1919 NAGLT1 HSPC100Q5TF392
Sodium-dependent neutral amino acid transporter B(0)AT2 (Fragment)SLC6A15F8VSG12
Sodium-dependent phosphate transport protein 1 (Na(+)/PI cotransporter 1) (Na/Pi-4) (Renal Na(+)-dependent phosphate cotransporter 1) (Renal sodium-dependent phosphate transport protein 1) (Renal sodium-phosphate transport protein 1) (Sodium/phosphate cotransporter 1) (Solute carrier family 17 member 1)SLC17A1 NPT1Q149162
Sodium-dependent phosphate transport protein 2C (Sodium-phosphate transport protein 2C) (Na(+)-dependent phosphate cotransporter 2C) (Sodium/inorganic phosphate cotransporter IIC) (Sodium/phosphate cotransporter 2C) (Na(+)/Pi cotransporter 2C) (NaPi-2c) (Solute carrier family 34 member 3)SLC34A3 NPT2C NPTIICQ8N1302
Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10)SLC4A10 NCBEQ6U8412
Sodium/calcium exchanger 2SLC8A2F5H6L72
Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)SLC8A3 NCX3P571032
Sodium/hydrogen exchanger 11 (Na(+)/H(+) exchanger 11) (NHE-11) (Solute carrier family 9 member 11) (Solute carrier family 9 member C2)SLC9C2 SLC9A11Q5TAH22
Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6)SLC9A6 KIAA0267 NHE6Q925812
Sodium/potassium-transporting ATPase subunit alpha (EC 3.6.3.-)0B3KW932
Sodium/potassium-transporting ATPase subunit alpha (EC 3.6.3.-)0B4DIQ82
Sodium/potassium-transporting ATPase subunit alpha-1 (Fragment)ATP1A1Q5TC052
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)ATP1A1B7Z3U62
Sodium/potassium-transporting ATPase subunit alpha-3ATP1A3A0A0A0MT262
Sodium/potassium-transporting ATPase subunit beta (Fragment)ATP1B3Q58I182
Sodium/potassium-transporting ATPase subunit beta-3 (Fragment)ATP1B3H7C4L92
Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)CANT1 SHAPYQ9BSD52
Soluble lamin-associated protein of 75 kDaFAM169AD6RB012
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Fragment)SSC5DM0QZ172
Solute carrier family 12 member 3SLC12A3J3QSS12
Solute carrier family 12 member 8 (Cation-chloride cotransporter 9)SLC12A8 CCC9A0AV022
Solute carrier family 13 member 1 (Renal sodium/sulfate cotransporter) (Na(+)/sulfate cotransporter) (hNaSi-1)SLC13A1 NAS1 NASI1Q9BZW22
Solute carrier family 2, facilitated glucose transporter member 10 (Glucose transporter type 10) (GLUT-10)SLC2A10 GLUT10O955282
Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1)SLC2A8 GLUT8 GLUTX1Q9NY642
Solute carrier family 22 member 2SLC22A2Q5T7Q52
Solute carrier family 22 member 9 (Organic anion transporter 7)SLC22A9 hOAT4 OAT7 UST3Q8IVM82
Solute carrier family 25 member 51 (Mitochondrial carrier triple repeat protein 1)SLC25A51 MCART1Q9H1U92
Solute carrier family 26 member 10SLC26A10Q8NG042
Solute carrier family 35 member F2SLC35F2Q149632
Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog)SLC35F6 C2orf18 UNQ3047/PRO9863Q8NBX62
Solute carrier organic anion transporter family member 1C1 (Organic anion transporter F) (OATP-F) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5) (Organic anion-transporting polypeptide 14) (OATP-14) (Solute carrier family 21 member 14) (Thyroxine transporter)SLCO1C1 OATP14 OATP1C1 OATPF SLC21A14Q9NYB52
Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)SLCO4A1 OATP1 OATP4A1 OATPE SLC21A12Q9NWX82
Son of sevenless homolog 2SOS2G3V5W32
Sonic hedgehog protein (SHH) (HHG-1) [Cleaved into: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product]SHHQ154652
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