EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)SORDQ166822
Sorting nexin0B2RAU52
Sorting nexin 12 (Sorting nexin 12, isoform CRA_a) (cDNA, FLJ93438, Homo sapiens sorting nexin 12 (SNX12), mRNA)SNX12 hCG_1990496Q3SYF12
Sorting nexin-14SNX14Q9Y5W72
Sorting nexin-27SNX27A0A0C4DFU62
Sorting nexin-3 (Protein SDP3)SNX3O607182
Sorting nexin-32 (Sorting nexin-6B)SNX32 SNX6BQ86XE02
SPARC (Fragment)SPARCF5GY032
Spectrin alpha chain, non-erythrocytic 1SPTAN1A0A0D9SGF62
Spectrin beta chainSPTBN1A0A087WUZ32
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)SPTBN1 SPTB2Q53R992
Spectrin-like protein of the nuclear envelope and GolgiSYNE1Q7RTM42
Sperm-associated antigen 17 (Projection protein PF6 homolog)SPAG17Q6Q7592
Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4) (SUN domain-containing protein 4)SPAG4 SUN4Q9NPE62
Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)SRM SPS1 SRML1Q155112
Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase)SMSQ9UQS12
Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8)S1PR5 EDG8Q9H2282
Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)SPHK1 SPHK SPKQ9NYA12
Spindlin-3 (Spindlin-like protein 3) (SPIN-3)SPIN3Q5JUX02
Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)SF1 ZFM1 ZNF162Q159132
Splicing factor 3B subunit 2SF3B2E9PPJ02
Splicing factor 3B subunit 3 (Fragment)SF3B3J3QKV42
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)SF3B3 KIAA0017 SAP130Q6NTI82
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)U2AF1 U2AF35 U2AFBP FP793Q701P42
Splicing factor, arginine/serine-rich 2 variant (Fragment)0Q53FN02
SRA stem-loop-interacting RNA-binding protein, mitochondrialSLIRPG3V2S92
SRP72 protein (Fragment)SRP72A0PJJ52
Stannin (AG8_1)SNNO753242
Stanniocalcin-1 (STC-1)STC1 STCQ71UE52
Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator)SND1 TDRD11Q131222
Sterile alpha motif domain-containing protein 14 (SAM domain-containing protein 14)SAMD14Q8IZD02
Sterol regulatory element-binding protein cleavage-activating proteinSCAPF8W9W72
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)SCAP KIAA0199 PSEC0227Q127702
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)HSPA9 GRP75 HSPA9B mt-HSP70B2RCM12
Stress-70 protein, mitochondrial (Fragment)HSPA9D6RA732
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)STIP1B4DM702
Striatal apoptosis-inducing factor (Fragment)0Q5RZA02
Striatin-interacting protein 2 (Protein FAM40B)STRIP2 FAM40B KIAA1170Q9ULQ02
Stromal interaction molecule 1 (Fragment)STIM1H0YDB22
Structural maintenance of chromosomes proteinSMC4E9PD532
Structure specific recognition protein 1 variant (Fragment)0Q59GH72
Succinate dehydrogenase (quinone) (EC 1.3.5.1) (Fragment)SDHAQ0QF122
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL)SDHC CYB560 SDH3Q996432
Succinate dehydrogenase [ubiquinone] cytochrome b small subunitSDHDE9PK732
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit)SDHD SDH4O145212
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp)SDHA SDH2 SDHFE9PBJ52
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)SUCLA2Q7Z5032
Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase)SUGCT C7orf10 DERP13Q9HAC72
Sugar phosphate exchanger 3 (Fragment)SLC37A3H7C4Z52
SULF1 proteinSULF1Q6NUJ92
SULF2 protein (Fragment)SULF2Q6DKK32
Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2)SLC26A2 DTD DTDSTB2R6J12
Sulfite oxidase, mitochondrial (EC 1.8.3.1)SUOXP516872
Sulfotransferase (EC 2.8.2.-)SULT1C2B8ZZF72
Sulfotransferase (EC 2.8.2.-)SULT1C2B4DLP02
Sulfurtransferase (Fragment)0Q53EW82
SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)SUN1 KIAA0810 UNC84AO949012
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)SOD1H7BYH42
Suppressor APC domain-containing protein 1 (Protein G7d)SAPCD1 C6orf26 G7D NG23Q5SSQ62
Surfeit locus protein 4SURF4 SURF-4Q9UNZ12
Survival motor neuron protein (cDNA FLJ60754, moderately similar to Survival motor neuron protein)SMN2 SMN1B4DP612
Sushi repeat-containing protein SRPXSRPX ETX1G3V1L02
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)SMARCC2 BAF170F8VTJ52
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, isoform CRA_c (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1)SMARCB1 hCG_41099G5E9752
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2SMARCD2J3KMX22
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (Fragment)SMARCD2J3KT182
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)SMARCE1 BAF57C0IMW52
Synaptic vesicle 2-related protein (SV2-related protein)SVOPQ8N4V22
Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-)VAT1Q9BUT82
Synaptic vesicle membrane protein VAT-1 homolog (Fragment)VAT1K7ENX22
Synaptic vesicle membrane protein VAT-1 homolog (Fragment)VAT1K7ERT72
Synaptic vesicular amine transporter (Monoamine transporter) (Solute carrier family 18 member 2) (Vesicular amine transporter 2) (VAT2)SLC18A2 SVMT VMAT2Q059402
Synaptogyrin-2SYNGR2K7ENG92
Synaptogyrin-2 (Cellugyrin)SYNGR2 UNQ352/PRO615Q3KQZ22
Synaptogyrin-2 (Cellugyrin)SYNGR2 UNQ352/PRO615O437622
Synaptojanin-2SYNJ2E7ER602
Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)SYNJ2 KIAA0348O150562
Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2)SYCP2 SCP2Q9BX262
Synaptophysin (Fragment)SYPH7C4W32
SynaptoporinSYNPRQ8TBG92
Synaptosomal-associated protein (Fragment)SNAP23H3BP152
Synaptosomal-associated protein 29 (Fragment)SNAP29C9JAF72
Synaptotagmin I, isoform CRA_b (Synaptotagmin-1)SYT1 hCG_2016754J3KQA02
Synaptotagmin-12 (Synaptotagmin XII) (SytXII)SYT12Q8IV012
Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV)SYT14Q8NB592
Synaptotagmin-2 (Synaptotagmin II) (SytII)SYT2Q8N9I02
Synaptotagmin-9 (Synaptotagmin IX) (SytIX)SYT9Q86SS62
SYNCRIP protein (Fragment)SYNCRIPQ05CK92
Syndecan-1 (SYND1) (CD antigen CD138)SDC1 SDCQ96HB72
Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)SDC4Q6FGN32
Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)SDC4Q53FN92
Synembryn-B (Brain synembryn) (hSyn) (Protein Ric-8B)RIC8BQ9NVN32
Syntaxin-18 (Cell growth-inhibiting gene 9 protein)STX18 GIG9Q9P2W92
Syntaxin-3STX3 STX3AO437512
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)STX4 STX4AQ155252
Syntaxin-7STX7Q5SZW22
Syntaxin-binding protein 2 (Fragment)STXBP2M0R1A12
Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C)STXBP3Q9UPD72
Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)STXBP5L KIAA1006 LLGL4Q9Y2K92
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)SDCBP MDA9 SYCLB7ZLN22
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