EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
V2-17 protein (Fragment)V2-17Q5NV902
V2-6 protein (Fragment)V2-6A2MYD52
Vacuolar fusion protein MON1 homolog AMON1A SAND1Q86VX92
Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26)VPS26A VPS26B2RDD32
Vacuolar protein sorting-associated protein 28 homolog (Fragment)VPS28E9PR042
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)VPS28Q86VK02
Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29)VPS29 DC15 DC7 MDS007Q9NRP12
Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)VPS35 MEM3 TCCCTA00141Q9NRS72
Vacuolar protein sorting-associated protein 45VPS45A0A087WU652
Vacuolar protein sorting-associated protein 8 homologVPS8C9JJN92
Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)VTA1 C6orf55 HSPC228 My012E7ETQ72
Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)VTA1 C6orf55 HSPC228 My012Q9P0Q02
Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25)VPS25 DERP9 EAP20B2R5812
Vacuolar-sorting protein SNF8 (Fragment)SNF8H0Y8S52
Valacyclovir hydrolaseBPHLF2Z2Q12
Valacyclovir hydrolase (Fragment)BPHLH7C0M32
Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA)BPHL MCNAAQ86WA62
Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)VARS G7A VARS2Q9UQM22
VAMP3 protein (Vesicle-associated membrane protein 3 (Cellubrevin)) (cDNA, FLJ92013, Homo sapiens vesicle-associated membrane protein 3 (cellubrevin)(VAMP3), mRNA)VAMP3 hCG_21813Q6FGG22
Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1)VIPR1P322412
Vasodilator-stimulated phosphoprotein (Fragment)VASPK7ENR72
Vasodilator-stimulated phosphoprotein (Fragment)VASPK7EIG82
Vasopressin V2 receptorAVPR2F8WET12
Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1)HSD17B12 SDR12C1Q96EA92
Vesicle transport protein SFT2C (SFT2 domain-containing protein 3)SFT2D3Q587I92
Vesicle transport through interaction with t-SNAREs homolog 1BVTI1BG3V5I22
Vesicle-associated membrane protein 8VAMP8B8ZZT42
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)NSFA8K2D92
Vesicular glutamate transporter 1 (VGluT1) (Brain-specific Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 7)SLC17A7 BNPI VGLUT1Q9P2U72
Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (hVIAAT)SLC32A1 VGAT VIAATQ9H5982
VezatinVEZTQ9HBM02
VH6DJ protein (Fragment)VH6DJA2N0T32
VH87-2 protein (Fragment)VH87-2A2N2G52
VimentinVIMQ548L22
Vinculin (Metavinculin) (MV)VCLQ5SWX22
Visual system homeobox 1 (Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1)VSX1 RINXQ9NZR42
Vitamin K-dependent protein CPROCE7END62
VitrinVIT UNQ647/PRO1277Q6UXI72
Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B]VTNB2R7G02
Voltage-dependent anion channel 2, isoform CRA_aVDAC2 hCG_23984A0A024QZN92
Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2)VDAC2Q6IB402
Voltage-dependent calcium channel gamma-6 subunit (Neuronal voltage-gated calcium channel gamma-6 subunit)CACNG6Q9BXT22
Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage-gated calcium channel gamma-7 subunit) (Transmembrane AMPAR regulatory protein gamma-7) (TARP gamma-7)CACNG7P629552
Voltage-dependent calcium channel subunit alpha-2/delta-1CACNA2D1E7ERK32
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Fragment)CACNA2D1H0Y7152
Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3]CACNA2D3Q8IZS82
Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3)CACNA1D CACH3 CACN4 CACNL1A2 CCHL1A2Q016682
Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage-gated calcium channel subunit alpha Cav1.4)CACNA1F CACNAF1O608402
Voltage-dependent N-type calcium channel subunit alphaCACNA1BE9PDR32
Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1)KCNAB1 KCNA1BQ147222
von Willebrand factor A domain-containing protein 5B1VWA5B1Q5TIE32
VPS10 domain-containing receptor SorCS3SORCS3 KIAA1059Q9UPU32
VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1)CACHD1 KIAA1573 VWCD1Q5VU972
WAS protein family homolog 6 (Protein FAM39A)WASH6P CXYorf1 FAM39AQ9NQA32
WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog)WIPF3 CR16A6NGB92
WD repeat and coiled-coil-containing proteinWDCP C2orf44 PP384Q9H6R72
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (Atg18 protein homolog) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa)WIPI1 WIPI49Q5MNZ92
WD repeat, SAM and U-box domain-containing protein 1WDSUB1 WDSAM1Q8N9V32
WD repeat-containing protein 18WDR18O603902
WD repeat-containing protein 49WDR49Q8IV352
WD repeat-containing protein 61WDR61H0YMF92
WD repeat-containing protein 61 (Fragment)WDR61H0YN812
WD repeat-containing protein 73WDR73 HSPC264Q6P4I22
WD repeat-containing protein 89WDR89 C14orf150 MSTP050Q96FK62
Whirlin (Autosomal recessive deafness type 31 protein)WHRN DFNB31 KIAA1526Q9P2022
WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)WISP3 CCN6 UNQ462/PRO790/PRO956O953892
WUGSC:H_LUCA15.1 proteinWUGSC:H_LUCA15.1Q6LCB52
WW domain binding protein 1-like (Outcome predictor in acute leukemia 1)WBP1L C10orf26 OPA1LQ9NX942
WW domain-binding protein 2 (cDNA FLJ59459, highly similar to WW domain-binding protein 2)WBP2A6NG102
WW domain-binding protein 2 (Fragment)WBP2K7EIJ02
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)WWOX FOR SDR41C1 WOX1Q9NZC72
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))XRCC5 G22P2Q0Z7V02
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)XRCC6 G22P1B1AHC82
Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)XPNPEP1 XPNPEPL XPNPEPL1G5E9Y22
XTP3TPA-transactivated protein 1XTP3TPATP1Q1KSF82
YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1)YEATS4 GAS41O956192
Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5)ZBTB14 ZFP161 ZNF478O438292
Zinc finger and BTB domain-containing protein 38ZBTB38Q8NAP32
Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain)ZBTB6 ZID ZNF482Q159162
Zinc finger and SCAN domain-containing protein 12 (Zinc finger protein 305) (Zinc finger protein 96)ZSCAN12 KIAA0426 ZNF305 ZNF96O433092
Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)ZSCAN22 HKR2 ZNF50P100732
Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127)ZC4H2 HCA127 KIAA1166Q9NQZ62
Zinc finger CCCH domain-containing protein 10ZC3H10 ZC3HDC10Q96K802
Zinc finger CCCH domain-containing protein 6ZC3H6 KIAA2035 ZC3HDC6P611292
Zinc finger CCCH-type with G patch domain-containing protein (G patch domain-containing protein 6) (Zinc finger CCCH domain-containing protein 9) (Zinc finger and G patch domain-containing protein)ZGPAT GPATC6 GPATCH6 KIAA1847 ZC3H9 ZC3HDC9 ZIPQ8N5A52
Zinc finger CCHC domain-containing protein 24ZCCHC24 C10orf56Q8N2G62
Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1)ZFYVE1 DFCP1 KIAA1589 TAFF1 ZNFN2A1 PP10436Q9HBF42
Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)ZFHX4Q86UP32
Zinc finger matrin-type protein 4ZMAT4Q9H8982
Zinc finger MYM-type protein 1ZMYM1Q5SVZ62
Zinc finger MYM-type protein 6 (Transposon-derived Buster2 transposase-like protein) (Zinc finger protein 258)ZMYM6 Buster2 KIAA1353 ZNF258O957892
Zinc finger protein 1 homolog (Zfp-1) (Zinc finger protein 475)ZFP1 ZNF475Q6P2D02
Zinc finger protein 100ZNF100Q8IYN02
Zinc finger protein 101 (Zinc finger protein HZF12)ZNF101Q8IZC72
Zinc finger protein 114ZNF114Q8NC262
Zinc finger protein 134ZNF134M0R2462
Zinc finger protein 143 (SPH-binding factor) (Selenocysteine tRNA gene transcription-activating factor) (hStaf)ZNF143 SBF STAFP527472
Zinc finger protein 185 (Fragment)ZNF185H0Y7042
Zinc finger protein 197 (Zinc finger protein with KRAB and SCAN domains 9) (ZnF20) (pVHL-associated KRAB domain-containing protein)ZNF197 ZKSCAN9 ZNF166O147092
Zinc finger protein 205 (Zinc finger protein 210)ZNF205 ZNF210O952012
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