EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
26S proteasome non-ATPase regulatory subunit 6 (Fragment)PSMD6C9J7B71
26S proteasome non-ATPase regulatory subunit 7PSMD7H3BNT71
26S proteasome non-ATPase regulatory subunit 8PSMD8K7ENY61
26S proteasome non-ATPase regulatory subunit 9PSMD9F5H1691
26S proteasome regulatory subunit 10B (Fragment)PSMC6H0YJX21
26S proteasome regulatory subunit 7 (Fragment)PSMC2C9JLS91
26S proteasome regulatory subunit 8PSMC5J3QSE01
26S proteasome regulatory subunit 8 (Fragment)PSMC5J3KRP21
26S proteasome regulatory subunit 8 (Fragment)PSMC5J3QSA91
28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt) (Mitochondrial small ribosomal subunit protein mS27)MRPS27 KIAA0264B4DRT21
28S ribosomal protein S35, mitochondrialMRPS35F5H6121
28S ribosomal protein S35, mitochondrial (Fragment)MRPS35H0YFD11
28S ribosomal protein S36, mitochondrialMRPS36D6R9411
3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3-beta-HSD VII) (3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase) (C(27) 3-beta-HSD) (EC 1.1.1.-) (Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase) (EC 1.1.1.181)HSD3B7Q9H2F31
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]HSD3B1 3BH HSDB3AP140601
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (Fragment)HSD3B1E9PRN71
3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP)BPNT1B4DUS91
3'(2'),5'-bisphosphate nucleotidase 1 (Fragment)BPNT1F8W1J01
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)HMGCRP040351
3-hydroxybutyrate dehydrogenase type 2BDH2D6RBF61
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)HIBADHQ546Z21
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmicHMGCLL1D6RHJ21
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (Hydroxymethylglutaricaciduria), isoform CRA_b (cDNA FLJ16378 fis, clone TKIDN2016399, highly similar to Hydroxymethylglutaryl-CoA lyase, mitochondrial (EC 4.1.3.4))HMGCL hCG_37683B1AK131
3-ketoacyl-CoA thiolase, peroxisomal (cDNA FLJ54941, highly similar to 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16)) (cDNA, FLJ79450, highly similar to 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16))ACAA1B4DVF41
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)SRD5A1P184051
3-phosphoinositide-dependent protein kinase 1 (Fragment)PDPK1H3BQ101
39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10) (39S ribosomal protein L8, mitochondrial) (L8mt) (MRP-L8) (Mitochondrial large ribosomal subunit protein uL10m)MRPL10 MRPL8 RPML8A6NGJ41
39S ribosomal protein L15, mitochondrial (Fragment)MRPL15E5RHF41
39S ribosomal protein L32, mitochondrial (Fragment)MRPL32H7BZU91
39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32) (Mitochondrial large ribosomal subunit protein bL32m)MRPL32 HSPC283Q9BYC81
39S ribosomal protein L52, mitochondrial (Fragment)MRPL52G3V4J11
39S ribosomal protein L55, mitochondrial (Mitochondrial ribosomal protein L55, isoform CRA_b)MRPL55 hCG_42248X6R6311
4-aminobutyrate aminotransferase, mitochondrialABATH3BNQ71
4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase) (Protein 569272)HOGA1 C10orf65 DHDPSLQ5T6841
4-hydroxyphenylpyruvate dioxygenaseHPDA0A0B4J1R41
4.1G isoform (Band 4.1-like protein 2)EPB41L2Q6R5J71
40S ribosomal protein S13 (Fragment)RPS13E9PS501
40S ribosomal protein S15 (Fragment)RPS15S4R4561
40S ribosomal protein S15 (Ribosomal protein S15, isoform CRA_a)RPS15 hCG_21570A0A0B4J2B41
40S ribosomal protein S15a (Small ribosomal subunit protein uS8)RPS15A OK/SW-cl.82Q3MHD91
40S ribosomal protein S16 (Fragment)RPS16M0R1M51
40S ribosomal protein S18 (HCG1777176, isoform CRA_a) (Ribosomal protein S18) (Ribosomal protein S18, isoform CRA_a)RPS18 hCG_1640167 hCG_1777176J3JS691
40S ribosomal protein S19 (Fragment)RPS19M0QXK41
40S ribosomal protein S2RPS2E9PPT01
40S ribosomal protein S2 (Fragment)RPS2E9PMM91
40S ribosomal protein S2 (Fragment)RPS2H3BNG31
40S ribosomal protein S21RPS21Q8WVC21
40S ribosomal protein S27 (Metallopan-stimulin 1) (MPS-1) (Small ribosomal subunit protein eS27)RPS27 MPS1Q5T4L61
40S ribosomal protein S3aRPS3AA8K4W01
40S ribosomal protein S3a (Fragment)RPS3AD6RED71
40S ribosomal protein S3a (Ribosomal protein S3A, isoform CRA_e)RPS3A hCG_2026261D6R9B61
40S ribosomal protein S8RPS8 hCG_2031852Q5JR941
40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40)RPSA hCG_1997894A0A0C4DG171
45 kDa calcium-binding protein (Stromal cell derived factor 4, isoform CRA_a)SDF4 hCG_19193G3V1E21
4F2 cell-surface antigen heavy chain (Fragment)SLC3A2F5GZR91
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1 protein) (Protein kinase, AMP-activated, alpha 1 catalytic subunit, isoform CRA_b)PRKAA1 hCG_37338Q96E921
5'-AMP-activated protein kinase subunit gamma-2PRKAG2F8WDA11
5'-nucleotidase domain-containing protein 3 (Fragment)NT5DC3H7C3S81
5'-nucleotidase domain-containing protein 4NT5DC4Q86YG41
5-formyltetrahydrofolate cyclo-ligase (Fragment)MTHFSH3BMB91
5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)HTR2BP415951
5-hydroxytryptamine receptor 3E (5-HT3-E) (5-HT3E) (Serotonin receptor 3E)HTR3EA5X5Y01
5-methyltetrahydrofolate-homocysteine methyltransferaseMTRB7ZLW81
5-oxoprolinase (Fragment)OPLAHA0A087WY991
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)THAP12 DAP4 P52RIPK PRKRIR THAP0O434221
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]PFKFB1 F6PK PFRXP161181
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3PFKFB3Q5VX201
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)0B4DL861
6-phosphogluconolactonase (Fragment)PGLSM0R2611
60 kDa heat shock protein, mitochondrial (Fragment)HSPD1C9JL191
60 kDa heat shock protein, mitochondrial (Fragment)HSPD1E7EXB41
60S acidic ribosomal protein P0 (Fragment)RPLP0F8VU651
60S acidic ribosomal protein P1RPLP1H0YL571
60S acidic ribosomal protein P1 (Large ribosomal subunit protein P1)RPLP1 RRP1A6NIB21
60S ribosomal protein L10 (Fragment)RPL10A6QRI91
60S ribosomal protein L10 (Fragment)RPL10B8A6G21
60S ribosomal protein L11 (Fragment)RPL11Q5VVC91
60S ribosomal protein L13aRPL13AM0QZU11
60S ribosomal protein L17RPL17J3QLC81
60S ribosomal protein L17 (Fragment)RPL17J3KRB31
60S ribosomal protein L18 (Ribosomal protein L18, isoform CRA_b)RPL18 hCG_2000370G3V2031
60S ribosomal protein L21 (Fragment)RPL21M0R1811
60S ribosomal protein L22RPL22K7EKS71
60S ribosomal protein L23aRPL23AK7EMA71
60S ribosomal protein L26-like 1 (Fragment)RPL26L1E5RIT61
60S ribosomal protein L26-like 1 (Fragment)RPL26L1E5RHH11
60S ribosomal protein L27aRPL27AE9PJD91
60S ribosomal protein L28RPL28H0YLP61
60S ribosomal protein L3RPL3F8WCR11
60S ribosomal protein L3 (Fragment)RPL3H7C3M21
60S ribosomal protein L31 (Fragment)RPL31H7C2W91
60S ribosomal protein L35RPL35H0Y3A01
60S ribosomal protein L35aRPL35AF8WBS51
60S ribosomal protein L36RPL36J3QSB51
60S ribosomal protein L36aRPL36AH0Y5B41
60S ribosomal protein L36a-like (Large ribosomal subunit protein eL42-like)RPL36ALQ3B7A51
60S ribosomal protein L37a (Large ribosomal subunit protein eL43)RPL37AQ6FGF51
60S ribosomal protein L37a (Ribosomal protein L37a, isoform CRA_c)RPL37A hCG_16380C9J4Z31
60S ribosomal protein L38 (Fragment)RPL38J3KSP21
60S ribosomal protein L38 (Large ribosomal subunit protein eL38)RPL38B2R5A81
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