EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Cytohesin-interacting protein (Cytohesin binder and regulator) (CYBR) (Cytohesin-associated scaffolding protein) (CASP) (Cytohesin-binding protein HE) (Cbp HE) (Pleckstrin homology Sec7 and coiled-coil domains-binding protein)CYTIP PSCDBPO607591
Cytokine receptor common subunit beta (Fragment)CSF2RBB0QY071
Cytokine receptor common subunit gamma (Fragment)IL2RGD6RDW91
Cytokine receptor common subunit gamma (Fragment)IL2RGH0Y8J61
Cytoplasmic dynein 1 heavy chain 1 (Fragment)DYNC1H1H0YJ211
Cytoplasmic dynein 1 intermediate chain 1DYNC1I1A0A0A0MTG21
Cytoplasmic dynein 1 intermediate chain 2 (Fragment)DYNC1I2E9PGG11
Cytoplasmic dynein 1 intermediate chain 2 (Fragment)DYNC1I2E7EUM41
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)DYNC1LI2 DNCLI2 LIC2B4DZP41
Cytoplasmic dynein 1 light intermediate chain 2 (Fragment)DYNC1LI2J3KRI41
Cytoplasmic dynein 1 light intermediate chain 2 (Fragment)DYNC1LI2J3KRZ21
Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain)DYNC2LI1 D2LIC LIC3 CGI-60Q8TCX11
Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (h-CPEB) (hCPEB-1)CPEB1 CPEBQ9BZB81
Cytoplasmic polyadenylation element-binding protein 4CPEB4E5RJM01
Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)CPEB4 KIAA1673Q17RY01
Cytosolic 10-formyltetrahydrofolate dehydrogenase (Fragment)ALDH1L1C9IZ361
Cytosolic 5'-nucleotidase 1A (cN1A) (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IA) (cN-I) (cN-IA)NT5C1AQ9BXI31
Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3)CASTOR1 GATSL3Q8WTX71
Cytosolic carboxypeptidase 2AGBL2H9KV531
Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2)AGBL2 CCP2Q5U5Z81
Cytosolic carboxypeptidase-like protein 5 (Fragment)AGBL5C9JCE11
Cytosolic Fe-S cluster assembly factor NUBP2NUBP2H3BQR21
Cytosolic Fe-S cluster assembly factor NUBP2 (Fragment)NUBP2H3BRE11
Cytosolic phospholipase A2 delta (cPLA2-delta) (EC 3.1.1.4) (Phospholipase A2 group IVD)PLA2G4DQ86XP01
Cytosolic phospholipase A2 epsilon (cPLA2-epsilon) (EC 3.1.1.4) (Phospholipase A2 group IVE)PLA2G4EQ3MJ161
Cytosolic phospholipase A2 gamma (cPLA2-gamma) (EC 3.1.1.4) (Phospholipase A2 group IVC)PLA2G4CQ9UP651
Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II)NT5C2 NT5B NT5CP PNT5Q5JUV51
Cytotoxic and regulatory T-cell molecule (Class-I MHC-restricted T-cell-associated molecule) (CD antigen CD355)CRTAMO957271
D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)DRD4P219171
D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)D2HGDH D2HGDQ8N4651
D-amino acid oxidase activator (Protein G72)DAOA G72P591031
D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)DDOQ994891
Dachshund homolog 1 (Dach1)DACH1 DACHQ9UI361
DC-STAMP domain-containing protein 1DCST1Q5T1971
DCN1-like protein (Defective in cullin neddylation protein 1-like protein) (Fragment)DCUN1D1C9J0B21
DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)DCUN1D1 DCUN1L1 RP42 SCCROQ9H6M11
DCN1-like protein 2 (DCUN1 domain-containing protein 2) (Defective in cullin neddylation protein 1-like protein 2)DCUN1D2 C13orf17 DCUN1L2Q6PH851
DCN1-like protein 4DCUN1D4D6RGX71
DDB1- and CUL4-associated factor 11 (Fragment)DCAF11H0YL981
DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)DCAF12 KIAA1892 TCC52 WDR40AQ5T6F01
DDB1- and CUL4-associated factor 17DCAF17 C2orf37Q5H9S71
DDB1- and CUL4-associated factor 4-like protein 1 (WD repeat-containing protein 21B)DCAF4L1 WDR21BQ3SXM01
DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)DCAF5 BCRG2 KIAA1824 WDR22Q96JK21
DDX21 protein (Fragment)DDX21Q3SWU71
DDX60 protein (Fragment)DDX60Q6B0F71
DEAD box polypeptide 17 isoform p82 variant (Fragment)0Q59F661
DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a (Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16)DHX16 hCG_26008Q5SQH51
Death domain-containing protein 1DTHD1Q6ZMT91
Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)CRADD RAIDDP785601
Death effector domain containing, isoform CRA_b (Death effector domain-containing protein)DEDD hCG_20845B1AQP51
Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)DAPK2Q9UIK41
Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)DAPK3 ZIPKO432931
Death-associated protein kinase 3 (Fragment)DAPK3M0QYW51
Debrisoquine 4-hydroxylase mutant allele variant (Fragment)0Q59FG81
Decorin (Fragment)DCNF8VUF61
Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)DOCK3 KIAA0299 MOCAQ8IZD91
Dedicator of cytokinesis protein 4 (Fragment)DOCK4H0Y7H71
Dedicator of cytokinesis protein 8DOCK8A2A3691
Dedicator of cytokinesis protein 9 (cDNA FLJ45400 fis, clone BRHIP3028570)DOCK9Q6ZSL51
Defensin-6 (Defensin, alpha 6)DEFA6 DEF6Q015241
Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5)DEAF1 SPN ZMYND5O753981
Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Di-trans,poly-cis-decaprenylcistransferase) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)NUS1 C6orf68 NGBRQ96E221
Dehydrogenase/reductase SDR family member 11 (Fragment)DHRS11A0A087X0R11
Dehydrogenase/reductase SDR family member 2, mitochondrial (Fragment)DHRS2C9JZP61
Dehydrogenase/reductase SDR family member 7DHRS7A0A087X0Z71
Dehydrogenase/reductase SDR family member 7 (Fragment)DHRS7H0YJ661
Dehydrogenase/reductase SDR family member 7BDHRS7BJ3QLJ81
Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE)DHRS9 RDH15 SDR9C4 UNQ835/PRO1773Q9BPW91
Deleted in autism-related protein 1CXorf36 DIA1R UNQ1862/PRO3743Q9H7Y01
Deleted in azoospermia protein 2DAZ2Q131171
Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1)DLEC1 DLC1Q9Y2381
Delta(14)-sterol reductase (Fragment)TM7SF2H0YEN61
Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)DLL4 UNQ1895/PRO4341Q9NR611
Dematin (Fragment)DMTNE5RJC01
DENN domain-containing protein 1CDENND1CK7EM301
DENN domain-containing protein 2CDENND2CQ68D511
DENN domain-containing protein 3 (Fragment)DENND3H0YAW21
DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)DENND5A KIAA1091 RAB6IP1Q6IQ261
DENND4A protein (Fragment)DENND4AQ05C901
Deoxycytidine kinaseDCKD6RG381
Deoxycytidine kinase (dCK) (EC 2.7.1.74)DCKQ5TZY71
Deoxycytidylate deaminase (Fragment)DCTDD6RBJ91
Deoxyhypusine hydroxylase (Fragment)DOHHK7ERU81
Deoxyhypusine synthase (Fragment)DHPSM0QZT31
Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)DNTTIP1 C20orf167 TDIF1Q9H1471
Deoxyribonuclease gamma (DNase gamma) (EC 3.1.21.-) (DNase I homolog protein DHP2) (Deoxyribonuclease I-like 3) (DNase I-like 3) (Liver and spleen DNase) (LS-DNase) (LSD)DNASE1L3 DHP2 DNAS1L3Q136091
Deoxyribonuclease II (Fragment)0C0LQF21
Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) (Dornase alfa)DNASE1 DNL1 DRNIQ14UU91
Deoxyribonuclease-1-like 1 (Fragment)DNASE1L1Q5HY401
Deoxyribose-phosphate aldolase (Fragment)DERAE9PMH91
Deoxythymidylate kinase (Thymidylate kinase) variant (Fragment)0Q53F551
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialDUTH0YKI01
DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6)DEPTOR DEPDC6B4DN971
Dephospho-CoA kinase domain-containing protein (Fragment)DCAKDK7ESP41
Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)DSE SART2Q9UL011
Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product]DHHO433231
Desumoylating isopeptidase 2 (Fragment)DESI2B1APK71
DET1 homolog (De-etiolated-1 homolog)DET1Q7L5Y61
Developmental pluripotency-associated protein 3 (Stella-related protein)DPPA3 STELLARQ6W0C51
Developmentally-regulated GTP-binding protein 2 (Fragment)DRG2J3KRL51
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