EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)TRIM13 LEU5 RFP2 RNF77O608581
E3 ubiquitin-protein ligase TRIM17 (EC 2.3.2.27) (RING finger protein 16) (RING-type E3 ubiquitin transferase TRIM17) (Testis RING finger protein) (Tripartite motif-containing protein 17)TRIM17 RBCC RNF16 TERFQ9Y5771
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)TRIM63 IRF MURF1 RNF28 SMRZQ969Q11
E3 ubiquitin-protein ligase TRIM68 (EC 2.3.2.27) (RING finger protein 137) (RING-type E3 ubiquitin transferase TRIM68) (SSA protein SS-56) (SS-56) (Tripartite motif-containing protein 68)TRIM68 GC109 RNF137 SS56Q6AZZ11
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)TRIM71 LIN41Q2Q1W21
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)TRIM9 KIAA0282 RNF91Q9C0261
E3 ubiquitin-protein ligase TRIP12 (Fragment)TRIP12H7C2Y11
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)UHRF2 NIRF RNF107Q96PU41
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)XIAP API3 BIRC4 IAP3P981701
E3 ubiquitin-protein ligase XIAP (Fragment)XIAPB1AKU21
E3 ubiquitin-protein ligase XIAP (Fragment)XIAPB1AKU31
E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91)ZFP91 ZNF757 FKSG11Q96JP51
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)ZNRF3 KIAA1133 RNF203Q9ULT61
Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)CD69 CLEC2CQ071081
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)EGR1 KROX24 ZNF225P181461
Echinoderm microtubule-associated protein-like 1EML1G3V3J11
Echinoderm microtubule-associated protein-like 2EML2C9JRL61
Echinoderm microtubule-associated protein-like 2EML2A0A0C4DGQ71
Echinoderm microtubule-associated protein-like 2EML2K7EIK71
Echinoderm microtubule-associated protein-like 2 (Fragment)EML2K7EKG31
Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]ENOX1 PIG38Q8TC921
Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein)ENC1 KLHL37 NRPB PIG10O146821
Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog)EDARADDA8K7B51
Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog)EDARADDQ8WWZ31
Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39)ENTPD1 CD39Q86VV31
Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.6) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase)ENTPD4 KIAA0392 LALP70 LYSAL1Q9Y2271
Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-) (Lysosomal apyrase-like protein 1)ENTPD7 LALP1Q9NQZ71
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1ENPP1E9PE721
EEF1A1 proteinEEF1A1Q6NS351
EEF1G protein (Eukaryotic translation elongation factor 1 gamma) (Eukaryotic translation elongation factor 1 gamma, isoform CRA_c) (GIG35)EEF1G hCG_2039458Q53YD71
EF hand domain family, member D1 variant (Fragment)0Q59EU61
EF-hand and coiled-coil domain-containing protein 1 (Coiled-coil domain-containing protein 48)EFCC1 C3orf73 CCDC48Q9HA901
EF-hand calcium-binding domain-containing protein 14EFCAB14 KIAA0494O750711
EF-hand calcium-binding domain-containing protein 4A (Fragment)CRACR2BE9PHZ81
EF-hand calcium-binding domain-containing protein 7EFCAB7 KIAA1799A8K8551
EF-hand calcium-binding domain-containing protein 9EFCAB9A8MZ261
EF-hand domain-containing protein D1 (Fragment)EFHD1H7C0I01
EF-hand domain-containing protein D2 (Fragment)EFHD2H0Y4Y41
EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)EOGT AER61 C3orf64 EOGT1Q5NDL21
EGF-containing fibulin-like extracellular matrix protein 1 (Fragment)EFEMP1C9JUM41
Egl nine homolog 2 (EC 1.14.11.29) (Estrogen-induced tag 6) (HPH-3) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-PH1) (HIF-prolyl hydroxylase 1) (HPH-1) (Prolyl hydroxylase domain-containing protein 1) (PHD1)EGLN2 EIT6Q96KS01
Egl nine homolog 2 (Fragment)EGLN2M0QXR01
EH domain-binding protein 1 (Fragment)EHBP1B5MC861
EH domain-binding protein 1 (Fragment)EHBP1C9IYU21
EH domain-binding protein 1 (Fragment)EHBP1C9JEP11
EH domain-containing protein 1 (EH-domain containing 1, isoform CRA_a)EHD1 hCG_23386A0A024R5711
eIF2C2 protein (Fragment)EIF2C2A4FVC01
eIF3C protein (Fragment)EIF3CQ3B7B91
ElastinELNE7ENM01
ELAV-like proteinELAVL4B1APY81
Electrogenic sodium bicarbonate cotransporter 4 (NBCe2) (Solute carrier family 4 member 5)SLC4A5 NBC4Q9BY071
Electron transfer flavoprotein subunit alpha, mitochondrialETFAH0YM121
Electron transfer flavoprotein subunit beta (Fragment)ETFBM0QY671
ELKS/Rab6-interacting/CAST family member 1ERC1X6RLX01
ELKS/Rab6-interacting/CAST family member 1ERC1G8JLD31
ELL-associated factor 1EAF1Q96JC91
ELL-associated factor 2 (cDNA FLJ60185, highly similar to ELL-associated factor 2)EAF2B4DWJ31
ELM2 and SANT domain-containing protein 1 (Fragment)ELMSAN1C9JYU71
ELMO domain-containing protein 2 (Fragment)ELMOD2D6RJB51
ELMO domain-containing protein 3ELMOD3D6RHZ31
Elongation factor 1-alpha0Q9H2I71
Elongation factor 1-alpha (Fragment)0Q53GE91
Elongation factor 1-alpha (Fragment)0Q9NZS61
Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)EEF1A1 EEF1A EF1A LENG7Q6IQ151
Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)EEF1D EF1DB4DDU41
Elongation factor 1-delta (Fragment)EEF1DE9PK061
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)GFM1 EFG1E5KND51
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)GFM1 EFG1C9IZ011
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)GFM1 EFG1E5KND71
Elongation of very long chain fatty acids protein (EC 2.3.1.199) (Very-long-chain 3-oxoacyl-CoA synthase)ELOVL1Q502X71
Elongation of very long chain fatty acids protein 6 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL6) (ELOVL fatty acid elongase 6) (ELOVL FA elongase 6) (Fatty acid elongase 2) (hELO2) (Fatty acyl-CoA elongase) (Long-chain fatty-acyl elongase) (Very long chain 3-ketoacyl-CoA synthase 6) (Very long chain 3-oxoacyl-CoA synthase 6)ELOVL6 FACE LCEQ9H5J41
Elongator complex protein 1 (Fragment)ELP1H0YDF31
Elongator complex protein 3ELP3E5RG261
Elongator complex protein 3 (EC 2.3.1.48)ELP3B4DKA41
Elongator complex protein 3 (Fragment)ELP3H0YAP71
Elongin-A2 (EloA2) (RNA polymerase II transcription factor SIII subunit A2) (Transcription elongation factor B polypeptide 3B)ELOA2 TCEB3B TCEB3LQ8IYF11
Elongin-CELOCR4GMY81
Em:AC008101.5 protein (HCG1998895)Em:AC008101.5 hCG_1998895Q6ICK51
Em:AP000351.3 protein (Glutathione S-transferase theta 2, isoform CRA_a) (Glutathione S-transferase theta-2B)GSTT2B Em:AP000351.3 GSTT2 hCG_41095Q6ICJ41
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)EFS CASS3B4DJ561
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)EFS CASS3O432811
Ena/VASP-like protein (Fragment)EVLG3V2K51
Endogenous retroviral envelope protein HEMO (Endogenous retrovirus group MER34 member 1 Env polyprotein) (HERV-MER_4q12 provirus ancestral Env polyprotein) (Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame) (Human endogenous MER34 ORF) (HEMO) [Cleaved into: Endogenous retroviral envelope protein HEMO, secreted form (Endogenous retroviral envelope protein HEMO, 48 kDa form)]ERVMER34-1 HEMO LP9056Q9H9K51
Endogenous retrovirus group K member 104 Pro protein (HERV-K104 Pro protein) (HERV-K_5q13.3 provirus ancestral Pro protein) (EC 3.4.23.50) (Protease) (Proteinase) (PR)HERV-K104P631241
Endogenous retrovirus group K member 18 Env polyprotein (Envelope polyprotein) (HERV-K(C1a) envelope protein) (HERV-K110 envelope protein) (HERV-K18 envelope protein) (HERV-K18 superantigen) (HERV-K_1q23.3 provirus ancestral Env polyprotein) (IDDMK1,2 22 envelope protein) (IDDMK1,2 22 superantigen) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)]ERVK-18O420431
Endogenous retrovirus group K member 5 Gag polyprotein (HERV-K(II) Gag protein) (HERV-K_3q12.3 provirus ancestral Gag polyprotein) (Gag polyprotein)ERVK-5 ERVK5Q9HDB91
Endogenous retrovirus group K member 8 Rec protein (HERV-K115 Rec protein) (HERV-K_8p23.1 provirus Rec protein)ERVK-8P615751
Endogenous retrovirus group K member 9 Gag polyprotein (HERV-K(C6) Gag protein) (HERV-K109 Gag protein) (HERV-K_6q14.1 provirus ancestral Gag polyprotein) (Gag polyprotein)ERVK-9P631261
Endogenous retrovirus group S71 member 1 Env polyprotein (Envelope polyprotein) (HERV-T Env protein) (HERV-T_19q13.11 provirus ancestral Env polyprotein) [Includes: Surface protein (SU); Transmembrane protein (TM)]ERVS71-1P615501
Endogenous retrovirus group V member 2 Env polyprotein (HERV-V_19q13.41 provirus ancestral Env polyprotein 2)ERVV-2 ENVV2B6SEH91
Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1)NEIL1Q96FI41
Endonuclease V (Fragment)ENDOVE5RHX41
Endonuclease V (hEndoV) (EC 3.1.26.-) (Inosine-specific endoribonuclease)ENDOVQ8N8Q31
Endophilin-A2 (Fragment)SH3GL1M0QYE01
Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator)ERAP1 APPILS ARTS1 KIAA0525 UNQ584/PRO1154Q8NEL41
Endoplasmic reticulum aminopeptidase 2 (Fragment)ERAP2H0Y9X91
Endoplasmic reticulum metallopeptidase 1ERMP1E7ER771
Endoplasmic reticulum resident protein 29ERP29F8VY021
Endoplasmic reticulum resident protein 29 (Fragment)ERP29F8W1G01
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (Fragment)ERGIC2H0YHS01
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