EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Immunglobulin heavy chain variable region (Fragment)0Q0ZCJ61
Immunglobulin heavy chain variable region (Fragment)0Q0ZCG91
Immunglobulin heavy chain variable region (Fragment)0Q0ZCI21
Immunglobulin heavy chain variable region (Fragment)0Q0ZCI31
Immunglobulin heavy chain variable region (Fragment)0Q0ZCH41
Immunglobulin light chain variable region (Fragment)0Q8TE631
Immunoglobulin heavy constant gamma 1 (Fragment)IGHG1A0A0A0MS071
Immunoglobulin heavy variable 1-24IGHV1-24A0A0C4DH331
Immunoglobulin heavy variable 1-58IGHV1-58A0A0C4DH391
Immunoglobulin heavy variable 1/OR15-9 (non-functional) (Fragment)IGHV1OR15-9A0A0B4J2B81
Immunoglobulin heavy variable 2-70 (Ig heavy chain V-II region COR) (Ig heavy chain V-II region DAW) (Ig heavy chain V-II region OU) (Ig heavy chain V-II region SESS)IGHV2-70P018151
Immunoglobulin heavy variable 3-13 (Ig heavy chain V-III region BRO)IGHV3-13A0A0A0MS111
Immunoglobulin heavy variable 3-16 (non-functional) (Fragment)IGHV3-16A0A0C4DH301
Immunoglobulin heavy variable 3-23 (Ig heavy chain V-III region LAY) (Ig heavy chain V-III region POM) (Ig heavy chain V-III region TEI) (Ig heavy chain V-III region TIL) (Ig heavy chain V-III region TUR) (Ig heavy chain V-III region VH26) (Ig heavy chain V-III region WAS) (Ig heavy chain V-III region ZAP)IGHV3-23P017751
Immunoglobulin heavy variable 3-23 (Ig heavy chain V-III region LAY) (Ig heavy chain V-III region POM) (Ig heavy chain V-III region TEI) (Ig heavy chain V-III region TIL) (Ig heavy chain V-III region TUR) (Ig heavy chain V-III region VH26) (Ig heavy chain V-III region WAS) (Ig heavy chain V-III region ZAP)IGHV3-23P017781
Immunoglobulin J chain (Fragment)JCHAINC9JA051
Immunoglobulin kappa joining 5 (Fragment)IGKJ5A0A0A0MTA31
Immunoglobulin kappa variable 1-33 (Ig kappa chain V-I region AU) (Ig kappa chain V-I region Ka)IGKV1-33A0A087WZH91
Immunoglobulin kappa variable 1D-17IGKV1D-17A0A075B6S41
Immunoglobulin kappa variable 2D-26IGKV2D-26A0A0A0MRZ71
Immunoglobulin kappa variable 2D-29IGKV2D-29A0A087X0P61
Immunoglobulin kappa variable 2D-30IGKV2D-30A0A075B6S61
Immunoglobulin kappa variable 5-2 (Ig kappa chain V region EV15)IGKV5-2P063151
Immunoglobulin lambda constant 3 (Ig lambda chain C region DOT) (Ig lambda chain C region NEWM) (Ig lambda-3 chain C regions)IGLC3A0A075B6L01
Immunoglobulin lambda variable 1-51 (Ig lambda chain V-I region BL2) (Ig lambda chain V-I region EPS) (Ig lambda chain V-I region NEW) (Ig lambda chain V-I region NIG-64)IGLV1-51P068881
Immunoglobulin lambda variable 2-11 (Ig gamma lambda chain V-II region DOT) (Ig lambda chain V-II region BOH) (Ig lambda chain V-II region BUR) (Ig lambda chain V-II region NIG-58) (Ig lambda chain V-II region TRO) (Ig lambda chain V-II region WIN)IGLV2-11P804221
Immunoglobulin lambda variable 2-11 (Ig gamma lambda chain V-II region DOT) (Ig lambda chain V-II region BOH) (Ig lambda chain V-II region BUR) (Ig lambda chain V-II region NIG-58) (Ig lambda chain V-II region TRO) (Ig lambda chain V-II region WIN)IGLV2-11P017121
Immunoglobulin lambda variable 2-11 (Ig gamma lambda chain V-II region DOT) (Ig lambda chain V-II region BOH) (Ig lambda chain V-II region BUR) (Ig lambda chain V-II region NIG-58) (Ig lambda chain V-II region TRO) (Ig lambda chain V-II region WIN)IGLV2-11P017131
Immunoglobulin lambda variable 2-11 (Ig gamma lambda chain V-II region DOT) (Ig lambda chain V-II region BOH) (Ig lambda chain V-II region BUR) (Ig lambda chain V-II region NIG-58) (Ig lambda chain V-II region TRO) (Ig lambda chain V-II region WIN)IGLV2-11A0A075B6K31
Immunoglobulin lambda variable 2-8 (Ig lambda chain V-II region BO) (Ig lambda chain V-II region MGC)IGLV2-8P017101
Immunoglobulin lambda variable 3-1 (Ig lambda chain V-IV region Bau) (Ig lambda chain V-IV region MOL) (Ig lambda chain V-IV region X)IGLV3-1P017161
Immunoglobulin lambda variable 3-16IGLV3-16A0A075B6K01
Immunoglobulin lambda variable 5-45IGLV5-45A0A087WSX01
Immunoglobulin lambda variable 5-52IGLV5-52A0A0A0MRZ91
Immunoglobulin lambda variable 6-57 (Ig lambda chain V-VI region AR) (Ig lambda chain V-VI region EB4) (Ig lambda chain V-VI region NIG-48) (Ig lambda chain V-VI region SUT) (Ig lambda chain V-VI region WLT)IGLV6-57P063181
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein)ISLR2 KIAA1465 LINX UNQ1885/PRO4329Q6UXK21
Immunoglobulin superfamily member 10 (Fragment)IGSF10H7C4M21
Immunoglobulin superfamily member 21 (IgSF21)IGSF21Q96ID51
Immunoglobulin superfamily member 22 (IgSF22)IGSF22Q8N9C01
Immunoglobulin superfamily member 23 (Fragment)IGSF23H0Y7731
Immunoglobulin superfamily member 5 (IgSF5) (Junctional adhesion molecule 4) (JAM-4)IGSF5 JAM4Q9NSI51
Immunoglobulin-like domain-containing receptor 2ILDR2E9PNU31
Immunogobulin kappa, VJ region (Fragment)0A2NH541
Importin subunit alpha-1KPNA2J3QL071
Importin subunit alpha-3 (Fragment)KPNA4H7C4F61
Importin subunit alpha-5 (Fragment)KPNA1C9J3521
Importin subunit alpha-7 (Fragment)KPNA6Q5TFJ71
Importin subunit alpha-8 (Karyopherin subunit alpha-7)KPNA7A9QM741
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)KPNB1 NTF97B7ZAV61
Importin-11IPO11F8WDV01
Importin-4IPO4H0YK931
Importin-4 (Fragment)IPO4H0YN071
Importin-5 (Fragment)IPO5C9J8751
Inactive glycosyltransferase 25 family member 3 (Fragment)CERCAMB7ZBT01
Inactive heparanase-2 (Hpa2)HPSE2 HPA2Q8WWQ21
Inactive serine protease PAMR1 (Peptidase domain-containing protein associated with muscle regeneration 1) (Regeneration-associated muscle protease homolog)PAMR1 RAMP FP938 UNQ699/PRO1344Q6UXH91
Inactive serine/threonine-protein kinase PLK5 (Polo-like kinase 5) (PLK-5)PLK5 PLK5P FG060302Q496M51
Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)TEX14 SGK307Q8IWB61
Inactive tyrosine-protein kinase 7 (Fragment)PTK7C9JQR61
InaD-like proteinPATJA0A087WUZ61
InaD-like proteinPATJA0A0X1KG691
Indolethylamine N-methyltransferase (Indolamine N-methyltransferase) (EC 2.1.1.49) (EC 2.1.1.96) (Aromatic alkylamine N-methyltransferase) (Amine N-methyltransferase) (Arylamine N-methyltransferase) (Thioether S-methyltransferase) (TEMT)INMTO950501
Inhibitor of Bruton tyrosine kinase (Fragment)IBTKH0Y9N71
Inhibitor of growth protein 1ING1Q9UK531
Inhibitor of growth protein 3 (p47ING3)ING3 HSPC301Q9NXR81
Inhibitor of growth protein 4 (p29ING4)ING4 My036Q9UNL41
Inhibitor of growth protein 5 (p28ING5)ING5Q8WYH81
Inhibitor of nuclear factor kappa-B kinase subunit betaIKBKBE5RFT31
INO80 complex subunit E (Coiled-coil domain-containing protein 95)INO80E CCDC95Q8NBZ01
Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2)PPA2 HSPC124F8WDN91
Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (Putative oncogene protein hlc14-06-p)ITPA C20orf37 My049 OK/SW-cl.9Q9BYX01
Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)ITPR1 INSP3R1E7EPX71
Inositol 1,4,5-trisphosphate receptor type 3 variant (Fragment)0Q59ES21
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (Fragment)PPIP5K1H7C4361
Inositol hexakisphosphate kinase 3 (InsP6 kinase 3) (EC 2.7.4.21) (Inositol hexaphosphate kinase 3)IP6K3 IHPK3Q96PC21
Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1)IMPA1 IMPAB7Z6Q41
Inositol monophosphatase 2IMPA2K7EL651
Inositol monophosphatase 3 (Fragment)IMPAD1H0YB381
Inositol polyphosphate 1-phosphatase (Fragment)INPP1E7ENF21
Inositol polyphosphate 1-phosphatase (Fragment)INPP1C9J1281
Inositol polyphosphate 5-phosphatase KINPP5KC9JQW81
Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Skeletal muscle and kidney-enriched inositol phosphatase)INPP5K PPS SKIPQ9BT401
Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase)IPMK IMPKQ8NFU51
Inositol polyphosphate-5-phosphatase (Fragment)INPP5AQ9C0551
Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (IPK1 homolog) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase)IPPK C9orf12Q9H8X21
Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)ITPKAP236771
INPP1 protein (Inositol polyphosphate-1-phosphatase) (Inositol polyphosphate-1-phosphatase isoform 1) (Inositol polyphosphate-1-phosphatase, isoform CRA_a) (Putative uncharacterized protein INPP1)INPP1 hCG_24794Q6IBG41
Insulin receptor (Fragment)0A4ZPI21
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]INSRR IRRP146161
Insulin, isoform 2 (INS-IGF2 readthrough transcript protein)INS-IGF2F8WCM51
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)IDEQ5T5N21
Insulin-degrading enzyme (Fragment)IDEQ5T5N31
Insulin-like 3 (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain]INSL3 RLF RLNLP514601
Insulin-like growth factor 1 receptor (Fragment)IGF1RH0YNR01
Insulin-like growth factor binding protein 3 (Insulin-like growth factor-binding protein 3)IGFBP3A6XND01
Insulin-like growth factor binding protein 3 isoform b (Insulin-like growth factor-binding protein 3)IGFBP3A6XND11
Insulin-like growth factor binding protein 3, isoform CRA_b (Insulin-like growth factor-binding protein 3) (cDNA FLJ43234 fis, clone HCHON2002964, highly similar to Insulin-like growth factor-binding protein 3)IGFBP3 hCG_1735376B3KWK71
Insulin-like growth factor-binding protein 2IGFBP2C9JMY11
Insulin-like growth factor-binding protein 3 (Fragment)IGFBP3C9JMX41
Insulin-like growth factor-binding protein 3 (Fragment)IGFBP3H0Y4851
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