EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx)MXD3 BHLHC13 MAD3Q9BW111
Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4)MXD4 BHLHC12 MAD4Q145821
MAX gene-associated protein (Fragment)MGAH3BTN21
Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4)MLX BHLHD13 TCFL4Q9UH921
MBT domain-containing protein 1MBTD1Q05BQ51
Mdm2-binding protein (hMTBP)MTBPQ96DY71
Meckel syndrome type 1 protein (Fragment)MKS1J3QQP41
Mediator complex subunit 22 (Mediator of RNA polymerase II transcription subunit 22) (Fragment)MED22 RP11-244N20.9-005Q5T8T81
Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like)MED12L KIAA1635 TNRC11L TRALP TRALPUSH PRO0314Q86YW91
Mediator of RNA polymerase II transcription subunit 13 (Fragment)MED13LH0YIQ91
Mediator of RNA polymerase II transcription subunit 15MED15F8WEJ41
Mediator of RNA polymerase II transcription subunit 15 (Fragment)MED15C9JGN21
Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) (Fragment)MED15C9JM581
Mediator of RNA polymerase II transcription subunit 19 (Lung cancer metastasis-related protein 1) (Mediator complex subunit 19)MED19 LCMR1A0JLT21
Mediator of RNA polymerase II transcription subunit 20 (Fragment)MED20B7ZBQ11
Mediator of RNA polymerase II transcription subunit 24 (Fragment)MED24J3KSL11
Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78)MED25 ACID1 ARC92 PTOV2 TCBAP0758Q71SY51
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)MED28 EG1 FKSG20Q9H2041
Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33)MED7 ARC34 CRSP9O435131
Medium-chain-specific acyl-CoA dehydrogenase, mitochondrialACADME9PQA81
Medium-wave-sensitive opsin 1 (Green cone photoreceptor pigment) (Green-sensitive opsin) (GOP)OPN1MW GCPP040011
Megakaryocyte-associated tyrosine-protein kinase (Fragment)MATKK7ENL81
Meiosis inhibitor protein 1MEI1F5GZT01
Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1)MARF1 KIAA0430 LKAPQ9Y4F31
Meiosis-specific coiled-coil domain-containing protein MEIOC (Fragment)MEIOCC9J4A21
Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein)MEIOC C17orf104A2RUB11
Meiosis-specific kinetochore proteinMEIKINA0A087WXM91
Meiotic nuclear division protein 1 homologMND1D6R9E31
Meiotic nuclear division protein 1 homologMND1D6RIA01
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1)0A8I0M11
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)MC1R MSHRQ017261
Melanoma inhibitory activity protein 2MIA2Q96PC51
Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen)MAGEA2 MAGE2 MAGEA2A; MAGEA2B MAGE2 MAGEA2P433561
Melanoma-associated antigen B10 (MAGE-B10 antigen)MAGEB10Q96LZ21
Melanoma-associated antigen D4 (Fragment)MAGED4BH0Y8Z31
Melanoma-associated antigen E2 (Hepatocellular carcinoma-associated protein 3) (MAGE-E2 antigen)MAGEE2 HCA3Q8TD901
Melanoma-associated antigen H1 (Apoptosis-related protein 1) (APR-1) (MAGE-H1 antigen) (Restin)MAGEH1 APR1Q9H2131
Melanophilin (Fragment)MLPHC9JKV51
Melanotransferrin (Fragment)MELTFC9JVN11
Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6)PAQR6Q6TCH41
Membrane protein FAM174BFAM174BH3BTJ41
Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)MPP5Q4VBP41
Membrane-associated phosphatidylinositol transfer protein 1 (Fragment)PITPNM1E9PMZ61
Membrane-associated phosphatidylinositol transfer protein 1 (Fragment)PITPNM1E9PNU61
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (cDNA FLJ60243, highly similar to Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1))PKMYT1A6NHV61
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (cDNA FLJ61000, highly similar to Membrane-associated tyrosine- andthreonine-specific cdc2-inhibitory kinase (EC 2.7.11.1))PKMYT1B4DZM61
Membrane-bound transcription factor site-1 protease (Fragment)MBTPS1H3BV531
Membrane-spanning 4-domains subfamily A member 13 (Testis-expressed transmembrane protein 4)MS4A13Q5J8X51
Membrane-spanning 4-domains subfamily A member 7 (CD20 antigen-like 4) (CD20/FC-epsilon-RI-beta family member 4) (Four-span transmembrane protein 2)MS4A7 4SPAN2 CD20L4 CFFM4Q9GZW81
Meprin A subunit (EC 3.4.24.-) (Endopeptidase-2)MEP1B hCG_25081J3QKX51
Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta)MEP1BQ168201
Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)MIER1 KIAA1610Q8N1081
Mesoderm specific transcript homolog (Mouse) (Mesoderm specific transcript homolog (Mouse), isoform CRA_a)MEST hCG_18967 tcag7.331A4D1L91
Mesothelin (Fragment)MSLNH3BUX11
Mesothelin (Fragment)MSLNH3BMA11
Metabotropic glutamate receptor 2 (mGluR2)GRM2 GPRC1B MGLUR2Q144161
Metabotropic glutamate receptor 3 (Fragment)GRM3C9J2I21
Metabotropic glutamate receptor 3 (mGluR3)GRM3 GPRC1C MGLUR3Q148321
Metabotropic glutamate receptor 6 (mGluR6)GRM6 GPRC1F MGLUR6O153031
Metabotropic glutamate receptor 7 (Fragment)GRM7C9JU971
Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)MTF1Q148721
Metalloendopeptidase (EC 3.4.24.-)TLL1B7ZLW31
Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5)MPPE1 PGAP5 PP579Q53F391
Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A)TRABD2A C2orf89 TIKI1Q86V401
Metalloproteinase inhibitor 1 (Fragment)TIMP1Q5H9B41
Metalloreductase STEAP1 (Fragment)STEAP1H7C0D81
Metalloreductase STEAP2 (Fragment)STEAP2C9JLP21
Metallothionein0Q8TDC41
MetallothioneinMT1FH3BRY81
MetallothioneinMT1HH3BTC41
MetallothioneinMT1BH3BR341
Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL)MT1LQ930831
Metallothionein-3MT3H3BPK21
Metastasis-associated protein MTA3MTA3E7EQY41
Metaxin 1, isoform CRA_b (Metaxin-1)MTX1 hCG_1997325A0A0A0MRK61
MeteorinMETRNH3BSC81
Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (Peptidase M) (p67) (p67eIF2)METAP2F8VQZ71
Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (Peptidase M) (p67) (p67eIF2)METAP2F8VRR31
Methionine synthase (Fragment)MTRB1ANE31
Methionine--tRNA ligase, cytoplasmicMARSF8VPL71
Methionine--tRNA ligase, cytoplasmicMARSF8VS261
Methionine--tRNA ligase, cytoplasmic (Fragment)MARSH0YHV51
Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)MARS2Q96GW91
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)MSRB1 SEPX1 HSPC270Q9NZV61
Methyl-CpG binding domain protein 3, isoform CRA_b (Methyl-CpG-binding domain protein 3)MBD3 hCG_22692K7EIE81
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)MBD3L1 MBD3LQ8WWY61
Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding endonuclease 1) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase)MBD4 MED1O952431
Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5)MBD5 KIAA1461Q9P2671
Methyl-CpG-binding protein 2MECP2H7BY721
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (Fragment)MCCC2D6RD671
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrialMCCC1F5GYT81
Methylcytosine dioxygenase TET2 (EC 1.14.11.n2)TET2 KIAA1546 Nbla00191Q6N0211
Methylenetetrahydrofolate reductase (EC 1.5.1.20)MTHFRQ5SNW61
Methylmalonyl-CoA epimerase, mitochondrial (Fragment)MCEEH7BZS71
Methylosome subunit pIClnCLNS1AE9PJF41
Methylthioribulose-1-phosphate dehydrataseAPIPS4R3D61
Methyltransferase-like protein 13 (EC 2.1.1.-)METTL13 KIAA0859 CGI-01Q53EZ61
Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)METTL17 METT11D1Q9H7H01
Methyltransferase-like protein 24 (EC 2.1.1.-)METTL24 C6orf186Q5JXM21
Methyltransferase-like protein 6 (EC 2.1.1.-)METTL6Q8TCB71
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