EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Postacrosomal sheath WW domain-binding proteinWBP2NLF5H7L21
Postacrosomal sheath WW domain-binding proteinWBP2NLF8WCF81
Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2)KCNK5 TASK2O952791
Potassium channel subfamily T member 1 (Fragment)KCNT1C9JBV21
Potassium channel subfamily T member 1 (KCa4.1)KCNT1 KIAA1422B3KXF71
Potassium channel subfamily T member 1 (KCa4.1)KCNT1 KIAA1422B9EGP21
Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5)KCNA5P224601
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)KCNB1Q147211
Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2)KCNB2Q929531
Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4)KCNC1P485471
Potassium voltage-gated channel subfamily C member 3KCNC3E9PQY41
Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3)KCNC3Q140031
Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2)KCND2 KIAA1044Q9NZV81
Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)KCND3Q9UK171
Potassium voltage-gated channel subfamily E member 1 (Delayed rectifier potassium channel subunit IsK) (IKs producing slow voltage-gated potassium channel subunit beta Mink) (Minimal potassium channel)KCNE1P153821
Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2)KCNE3Q9Y6H61
Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1)KCNF1Q9H3M01
Potassium voltage-gated channel subfamily H member 1 (Ether-a-go-go potassium channel 1) (EAG channel 1) (h-eag) (hEAG1) (Voltage-gated potassium channel subunit Kv10.1)KCNH1 EAG EAG1O952591
Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (hERG-2) (hERG2) (Voltage-gated potassium channel subunit Kv11.2)KCNH6 ERG2Q9H2521
Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1)KCNQ1 KCNA8 KCNA9 KVLQT1P517871
Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5)KCNQ5A6PVT61
Potassium voltage-gated channel subfamily S member 3 (Delayed-rectifier K(+) channel alpha subunit 3) (Voltage-gated potassium channel subunit Kv9.3)KCNS3Q9BQ311
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3HCN3 KIAA1535Q9P1Z31
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4HCN4Q9Y3Q41
POTE ankyrin domain family member A (ANKRD26-like family A member 1) (Prostate, ovary, testis-expressed protein on chromosome 8) (POTE-8)POTEA A26A1 POTE8Q6S8J71
POTE ankyrin domain family member B (ANKRD26-like family B member 1) (Prostate, ovary, testis-expressed protein on chromosome 15) (POTE-15)POTEB A26B1 POTE15Q6S5H41
POTE ankyrin domain family member B (POTE ankyrin domain family member B2) (POTEB protein)POTEB POTEB2Q495V51
POTE ankyrin domain family member IPOTEIA0A087X0921
POU domain, class 2, transcription factor 2 (Fragment)POU2F2H0YNG11
POU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP)POU3F1 OCT6 OTF6Q030521
POU domain, class 4, transcription factor 1 (Brain-specific homeobox/POU domain protein 3A) (Brain-3A) (Brn-3A) (Homeobox/POU domain protein RDC-1) (Oct-T1)POU4F1 BRN3A RDC1Q018511
POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brain-3C) (Brn-3C)POU4F3 BRN3CQ153191
POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSGQ9HBE11
PP73020Q71RB01
PPM1G protein0Q6PJK31
PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)PRDM1 BLIMP1O756261
PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14)PRDM14Q9GZV81
PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298)PRDM15 C21orf83 ZNF298P570711
PRA1 family proteinARL6IP5F8WF331
PRA1 family proteinWDR45A6NM711
PRA1 family proteinARL6IP5F8WF901
PRA1 family protein (Fragment)RABAC1M0R1H91
PRAME family member 18PRAMEF18Q5VWM31
PRAME family member 2PRAMEF2O608111
PRAME family member 20PRAMEF20 PRAMEF21Q5VT981
PRAME family member 25PRAMEF25A6NGN41
PRAME family member 7PRAMEF7Q5VXH51
Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2) (Protein G17)PBX2 G17P404251
Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3)PBX3P404261
Pre-mRNA-processing factor 19 (Fragment)PRPF19H0YGF31
Pre-mRNA-processing factor 19 (Fragment)PRPF19F5H2I01
Pre-mRNA-processing factor 40 homolog B (Fragment)PRPF40BH0YII71
Pre-mRNA-processing factor 40 homolog B (Huntingtin yeast partner C) (Huntingtin-interacting protein C)PRPF40B HYPCQ6NWY91
Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25)CWC25 CCDC49Q9NXE81
Pre-mRNA-splicing regulator WTAP (Wilms tumor 1 associated protein, isoform CRA_f)WTAP hCG_34028A0A087X1R41
Predicted protein product of Nbla02942Nbla02942Q3LIE91
Prefoldin subunit 2 (cDNA, FLJ96845, Homo sapiens prefoldin 2 (PFDN2), mRNA)PFDN2 hCG_1995291B1AQP21
Prefoldin subunit 5PFDN5H3BMQ11
Pregnancy-specific beta-1-glycoprotein 3PSG3M0QX681
Pregnancy-specific beta-1-glycoprotein 6PSG6B5MCE11
Pregnancy-specific beta-1-glycoprotein 6PSG6M0QXW01
Pregnancy-specific beta-1-glycoprotein 6 (PS-beta-G-6) (PSBG-6) (Pregnancy-specific glycoprotein 6) (Pregnancy-specific beta-1-glycoprotein 10) (PS-beta-G-10) (PSBG-10) (Pregnancy-specific glycoprotein 10) (Pregnancy-specific beta-1-glycoprotein 12) (PS-beta-G-12) (PSBG-12) (Pregnancy-specific glycoprotein 12)PSG6 CGM3 PSG10 PSG12 PSGGBQ008891
Prelamin-A/CLMNAD6RB201
PRELI domain containing protein 3A (Protein slowmo homolog 1)PRELID3A C18orf43 SLMO1Q96N281
PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein)PRELID1 PRELI CGI-106 SBBI12Q9Y2551
Prenylcysteine oxidase 1 (Fragment)PCYOX1C9JGT61
Prenylcysteine oxidase 1 (Fragment)PCYOX1C9K0551
Prenylcysteine oxidase 1 (Fragment)PCYOX1C9JM551
Prenylcysteine oxidase-likePCYOX1LE7EVZ51
Presenilin-1 (Fragment)PSEN1G3V3Z01
Presenilin-1 (Fragment)PSEN1G3V4M01
Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]PSEN2 AD4 PS2 PSNL2 STM2P498101
Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]PARL PSARL PRO2207Q9H3001
Presynaptic protein SAP97 variant (Fragment)0Q59FC41
Prickle-like protein 2PRICKLE2Q7Z3G61
PRKCA protein (Fragment)PRKCAQ7Z7271
PRKCSH protein (Fragment)PRKCSHA2VCQ41
Pro-neuregulin-1, membrane-bound isoform (Fragment)NRG1H0YBA31
Pro-neuregulin-1, membrane-bound isoform (Fragment)NRG1H0YCP01
Pro-neuregulin-3, membrane-bound isoformNRG3R4GNI61
Pro-opiomelanocortin (Fragment)POMCE9PHK51
PRO10840Q9P1K71
PRO18210Q9H3B11
PRO24740Q9H3881
PRO27690Q9P1C51
Proactivator polypeptide-like 1 [Cleaved into: Saposin A-like; Saposin B-Val-like; Saposin B-like; Saposin C-like; Saposin D-like]PSAPL1Q6NUJ11
Probable 18S rRNA (guanine-N(7))-methyltransferase (cDNA FLJ33843 fis, clone CTONG2005110, moderately similar to methyltransferase WBSCR22 (EC 2.1.1.-))BUD23B3KR831
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (Fragment)NOP2F5GYR31
Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) (SEC63 domain-containing protein 1)HFM1 SEC3D1A2PYH41
Probable ATP-dependent RNA helicase DDX41 (Fragment)DDX41J3KNN51
Probable ATP-dependent RNA helicase DDX46DDX46A0A0C4DG891
Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47)DDX47G5E9551
Probable ATP-dependent RNA helicase DDX5 (Fragment)DDX5J3QLG91
Probable ATP-dependent RNA helicase DDX5 (Fragment)DDX5J3KRZ11
Probable ATP-dependent RNA helicase DDX5 (Fragment)DDX5J3QSF11
Probable ATP-dependent RNA helicase DDX5 (Fragment)DDX5J3QRQ71
Probable ATP-dependent RNA helicase DDX53 (EC 3.6.4.13) (Cancer-associated gene protein) (Cancer/testis antigen 26) (CT26) (DEAD box protein 53) (DEAD box protein CAGE)DDX53 CAGEQ86TM31
Probable ATP-dependent RNA helicase DDX60-like (EC 3.6.4.13) (DEAD box protein 60-like)DDX60LQ5H9U91
Probable ATP-dependent RNA helicase DHX58 (Fragment)DHX58K7EPP01
Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1)DPY19L1 GA0500 KIAA0877Q2PZI11
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