EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3)DPY19L3Q6ZPD91
Probable C-mannosyltransferase DPY19L4 (EC 2.4.1.-) (Dpy-19-like protein 4) (Protein dpy-19 homolog 4)DPY19L4Q7Z3881
Probable cation-transporting ATPase 13A4 (Fragment)ATP13A4H7C1P51
Probable crossover junction endonuclease EME2 (EC 3.1.22.-)EME2A4GXA91
Probable E3 ubiquitin-protein ligase DTX2 (Fragment)DTX2C9IYX11
Probable E3 ubiquitin-protein ligase HECTD4HECTD4J3KPF01
Probable E3 ubiquitin-protein ligase HERC3 (Fragment)HERC3C9JKA71
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)MID2 FXY2 RNF60 TRIM1Q9UJV31
Probable E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.-) (IBR domain-containing protein 1) (RING finger protein 217)RNF217 C6orf172 IBRDC1Q8TC411
Probable E3 ubiquitin-protein ligase RNF217 (Fragment)RNF217H0YB951
Probable E3 ubiquitin-protein ligase TRIML2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIML2) (SPRY domain-containing protein 6) (Tripartite motif family-like protein 2)TRIML2 SPRYD6Q8N7C31
Probable G-protein coupled receptor 101GPR101Q96P661
Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13)GPR141 PGR13Q7Z6021
Probable G-protein coupled receptor 156 (G-protein coupled receptor PGR28) (GABAB-related G-protein coupled receptor)GPR156 GABABL PGR28Q8NFN81
Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein)GPR162 GRCAQ165381
Probable G-protein coupled receptor 19 (GPR-NGA)GPR19Q157601
Probable G-protein coupled receptor 33GPR33Q49SQ11
Probable G-protein coupled receptor 34GPR34Q9UPC51
Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1)AMDHD1 HMFT1272Q96NU71
Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 (ACC synthase-like protein 2)ACCSLQ4AC991
Probable inactive ribonuclease-like protein 12RNASE12Q5GAN41
Probable inactive ribonuclease-like protein 13RNASE13Q5GAN31
Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1)METTL15 METT5D1A6NJ781
Probable N-acetyltransferase 16 (EC 2.3.1.-)NAT16 C7orf52Q8N8M01
Probable palmitoyltransferase ZDHHC19 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 19) (DHHC-19)ZDHHC19Q8WVZ11
Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378)ZDHHC8 KIAA1292 ZDHHCL1 ZNF378Q9ULC81
Probable peptidyl-tRNA hydrolasePTRH1C9J7Z11
Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)PTRH1 C9orf115Q86Y791
Probable protein phosphatase 1NPPM1NE7ENL91
Probable ribonuclease 11 (RNase 11) (EC 3.1.27.-)RNASE11 C14orf6 UNQ5832/PRO19669Q8TAA11
Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B)ZC3H12B CXorf32 MCPIP2Q5HYM01
Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C)ZC3H12C KIAA1726 MCPIP3B4DR471
Probable RNA-binding protein EIF1ADEIF1ADE9PQD01
Probable serine carboxypeptidase CPVL (Fragment)CPVLH7C0X51
Probable tRNA methyltransferase 9B (Fragment)TRMT9BE9PK201
Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1)OSGEPL1 GCP1Q9H4B01
Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-)TRUB2O959001
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)USP9X DFFRX FAM USP9Q8WX121
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (EC 3.4.19.12) (Probable deubiquitinating enzyme MINDY-4)MINDY4 C7orf67 FAM188BQ4G0A61
Probetacellulin [Cleaved into: Betacellulin (BTC)]BTCP350701
Procollagen C-endopeptidase enhancer 2PCOLCE2C9JYX91
Procollagen galactosyltransferase 2COLGALT2Q5SXQ51
Procollagen galactosyltransferase 2 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 2) (Glycosyltransferase 25 family member 2) (Hydroxylysine galactosyltransferase 2)COLGALT2 C1orf17 GLT25D2 KIAA0584Q8IYK41
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (Fragment)PLOD3H7C2S81
Proenkephalin-A (Fragment)PENKE5RFR11
ProfilinPFN2 hCG_21343G5E9Q61
ProfilinPFN2C9J2N01
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)PGR NR3C3P064011
Programmed cell death protein 10 (Fragment)PDCD10C9JSA31
Programmed cell death protein 10 (Fragment)PDCD10H7C5M91
Programmed cell death protein 5PDCD5K7EQA11
Progressive ankylosis protein homologANKHD6RGI51
Progressive rod-cone degeneration proteinPRCDQ00LT11
Prohibitin (Fragment)PHBE7ESE21
Prohibitin (Fragment)PHBC9JZ201
Prohibitin (Fragment)PHBD6RBK01
Prohibitin-2PHB2J3KPX71
Prohibitin-2PHB2F5H2D21
Prohibitin-2PHB2F5H0C51
Prolactin receptor (PRL-R)PRLRP164711
Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3)PRLHR GPR10 GR3P496831
Proliferation-associated protein 2G4PA2G4F8VR771
Proliferation-inducing gene 20 protein0Q5J7V81
Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein)PRODH PIG6 POX2 PRODH2O432721
Proline-rich acidic protein 1 (Epididymis tissue protein Li 178) (Uterine-specific proline-rich acidic protein)PRAP1 UPA UNQ608/PRO1195Q96NZ91
Proline-rich AKT1 substrate 1 (Fragment)AKT1S1M0R2V81
Proline-rich basic protein 1PROB1 C5orf65E7EW311
Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2)PNRC1 PROL2Q7Z5N01
Proline-rich protein 11 (Fragment)PRR11J3QKY41
Proline-rich protein 15PRR15Q8IV561
Proline-rich protein 23BPRR23BQ6ZRT61
Proline-rich protein 3 (MHC class I region proline-rich protein CAT56)PRR3 CAT56P795221
Proline-rich protein 30 (Fragment)PRR30C9JVA31
Proline-rich protein 36 (Fragment)PRR36A0A096LNU11
Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1)PRRT1 C6orf31 NG5Q999461
Proline-rich transmembrane protein 4PRRT4C9JH251
Proline/serine-rich coiled-coil protein 1PSRC1 DDA3 FP3214Q6PGN91
Prolyl 3-hydroxylase 1 (Fragment)P3H1E2QRI11
Prolyl 3-hydroxylase OGFOD1OGFOD1A0A0A0MTR21
Prolyl endopeptidase FAP (Fragment)FAPC9J1311
Prolyl endopeptidase FAP (Fragment)FAPH7C4D91
Promethin (Transmembrane protein 159)TMEM159Q96B961
Properdin (Fragment)CFPC9J7V51
Propionyl Coenzyme A carboxylase, beta polypeptide variant (Fragment)0Q59GV01
Propionyl-CoA carboxylase beta chain, mitochondrialPCCBE7ENC11
Propionyl-CoA carboxylase beta chain, mitochondrialPCCBE7ETT11
Propionyl-CoA carboxylase beta chain, mitochondrialPCCBE9PEC31
Proprotein convertase subtilisin/kexin type 6PCSK6H7BXT31
ProsaposinPSAPC9JIZ61
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)PROX1Q927861
Prospero homeobox protein 2 (Homeobox prospero-like protein PROX2) (PROX-2)PROX2Q3B8N51
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)PTGES3 P23 TEBPB4DP111
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)PTGER3P431151
Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1)PTGS1 COX1B4E2S51
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)PTGS2 COX2P353541
Prostaglandin reductase 1 (Fragment)PTGR1F2Z3J91
Prostaglandin reductase 1 (PRG-1) (EC 1.3.1.-) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (EC 1.3.1.74)PTGR1 LTB4DHF5GY501
Prostaglandin reductase 1 (PRG-1) (EC 1.3.1.-) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (EC 1.3.1.74)PTGR1 LTB4DHB4DPK31
Prostaglandin reductase 1 (PRG-1) (EC 1.3.1.-) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (EC 1.3.1.74)PTGR1 LTB4DHQ8IYQ01
Prostamide/prostaglandin F synthase (Fragment)FAM213BJ3QKK81
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