EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein transport protein Sec31ASEC31AD6RHZ51
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334Q9UM051
Protein transport protein Sec31B (SEC31-like protein 2) (SEC31-related protein B) (SEC31B-1)SEC31B SEC31L2Q9NQW11
Protein transport protein Sec61 subunit alpha isoform 2 (Fragment)SEC61A2C9JJV41
Protein transport protein Sec61 subunit betaSEC61BS4R3B51
Protein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)TSSC4Q9Y5U21
Protein turtle homolog B (Fragment)IGSF9BH0YDP11
Protein TXNRD3NB (Thioredoxin reductase 2 intronic transcript 1) (Thioredoxin reductase 3 intronic transcript 1) (Thioredoxin reductase 3 neighbor gene protein) (TXNRD3 neighbor gene protein) (Thioredoxin reductase 3 new transcript 1)TXNRD3NB TR2IT1 TXNRD3IT1 TXNRD3NT1Q6F5E71
Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)PTPDC1 PTP9Q22A2A3K41
Protein tyrosine phosphatase, non-receptor type 13 isoform 2 variant (Fragment)0Q59H551
Protein tyrosine phosphatase, receptor type, C (Receptor-type tyrosine-protein phosphatase C)PTPRCQ0VAE81
Protein unc-13 homolog BUNC13BF8W8M91
Protein unc-79 homologUNC79G3V2U41
Protein unc-93 homolog A (HmUnc-93A) (Unc-93A)UNC93AQ86WB71
Protein VAC14 homolog (Tax1-binding protein 2)VAC14 TAX1BP2 TRXB3KSM81
Protein virilizer homolog (Fragment)KIAA1429H0YBN51
Protein WFDC9WFDC9 WAP9Q8NEX51
Protein Wnt (Fragment)WNT5BF5H3641
Protein Wnt (Fragment)WNT5AC9J8I81
Protein Wnt-10aWNT10AQ9GZT51
Protein Wnt-4WNT4 UNQ426/PRO864P567051
Protein wntless homolog (Fragment)WLSE9PKJ01
Protein WWC3WWC3 KIAA1280Q9ULE01
Protein YIF1AYIF1AA6NGW11
Protein YIPF (Fragment)YIPF2K7EQH31
Protein YIPF1 (YIP1 family member 1)YIPF1Q9Y5481
Protein YIPF2 (YIP1 family member 2)YIPF2Q9BWQ61
Protein YIPF3 (Fragment)YIPF3D6RFI31
Protein YIPF5 (Fragment)YIPF5E5RGR91
Protein YIPF7 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9) (YIP1 family member 7)YIPF7 FINGER9 YIP1BQ8N8F61
Protein yippee-like 4YPEL4Q96NS11
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)ZER1 C9orf60 ZYG ZYG11BLQ7Z7L71
Protein ZNF738ZNF738M0R3I01
Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)SCYL3 PACE1Q8IZE31
Protein-glutamine gamma-glutamyltransferase 6 (EC 2.3.2.13) (Transglutaminase Y) (TGY) (TGase Y) (Transglutaminase-3-like) (TGase-3-like) (Transglutaminase-6) (TG6) (TGase-6)TGM6 TGM3LO959321
Protein-glutamine gamma-glutamyltransferase K (Fragment)TGM1H0YMQ81
Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77)0B7Z9721
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (Fragment)PCMT1H7C4X21
Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)ICMT PCCMTO607251
Protein-serine O-palmitoleoyltransferase porcupinePORCNF2Z3601
Protein-serine/threonine kinase (EC 2.7.11.-)0A8K8M51
Protein-serine/threonine kinase (EC 2.7.11.-)GRK2E9PRV71
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)PTK6 BRKQ138821
Protein/nucleic acid deglycase DJ-1 (Fragment)PARK7K7EN271
Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated), isoform CRA_b (Proteolipid protein 1 isoform 2) (cDNA FLJ77822, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA) (cDNA, FLJ92659, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA)PLP1 hCG_17970A8K9L31
Prothrombin (Fragment)F2C9JV371
Proto-oncogene tyrosine-protein kinase ROS (Fragment)ROS1H0Y3T91
Proto-oncogene vav (VAV1 protein)VAV1Q96D371
Protocadherin alpha-1 (PCDH-alpha-1)PCDHA1Q9Y5I31
Protocadherin alpha-10 (PCDH-alpha-10)PCDHA10 CNRS8Q9Y5I21
Protocadherin alpha-5 (PCDH-alpha-5)PCDHA5 CNRS6Q9Y5H71
Protocadherin alpha-8 (PCDH-alpha-8)PCDHA8Q9Y5H61
Protocadherin alpha-9 (PCDH-alpha-9)PCDHA9 KIAA0345Q9Y5H51
Protocadherin beta-11 (PCDH-beta-11)PCDHB11Q9Y5F21
Protocadherin beta-12 (PCDH-beta-12)PCDHB12Q9Y5F11
Protocadherin beta-13 (PCDH-beta-13)PCDHB13 UNQ332/PRO531Q9Y5F01
Protocadherin beta-7 (PCDH-beta-7)PCDHB7Q9Y5E21
Protocadherin gamma-A2 (PCDH-gamma-A2)PCDHGA2Q9Y5H11
Protocadherin gamma-A7 (PCDH-gamma-A7)PCDHGA7Q9Y5G61
Protocadherin gamma-A8 (PCDH-gamma-A8)PCDHGA8 KIAA0327Q9Y5G51
Protocadherin gamma-B3 (PCDH-gamma-B3)PCDHGB3Q9Y5G11
Protocadherin gamma-B6 (PCDH-gamma-B6)PCDHGB6Q9Y5F91
Protocadherin-10PCDH10 KIAA1400Q9P2E71
Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S)PCDH11X KIAA1326 PCDH11 PCDHXQ9BZA71
Protocadherin-15PCDH15A9Z1W11
Protocadherin-7 (Fragment)PCDH7A0A087X2C41
Protocadherin-7 (Fragment)PCDH7H0YAH01
Protocadherin-8 (Arcadlin)PCDH8O952061
Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase)COX10Q128871
Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4)SLC36A4 PAT4Q6YBV01
Protoporphyrinogen oxidase, isoform CRA_dPPOX hCG_1766487D3DVG21
PRR5-ARHGAP8 readthroughPRR5-ARHGAP8B1AHC31
Prune exopolyphosphatase 1 (Fragment)PRUNE1Q5SZF21
Pseudouridylate synthase 7 homologPUS7E7EUH71
PSM9 (cDNA FLJ54210, moderately similar to Proteasome subunit beta type 9 (EC 3.4.25.1))PSM9B4DZW21
PSMD3 proteinPSMD3Q6IBN01
PTB-containing, cubilin and LRP1-interacting protein (P-CLI1) (Phosphotyrosine interaction domain-containing protein 1) (Protein NYGGF4)PID1 NYGGF4 PCLI1 HMFN2073Q7Z2X41
Pterin-4-alpha-carbinolamine dehydratase 2 (Fragment)PCBD2H0YA521
PTGES3L-AARSD1 readthroughPTGES3L-AARSD1C9J5N11
PTGFRN protein (Fragment)PTGFRNQ4QQP81
PTK2 protein tyrosine kinase 2 isoform b variant (Fragment)0Q59GM61
PTPRM protein (Receptor-type tyrosine-protein phosphatase mu)PTPRMQ49AC91
Pulmonary surfactant-associated protein A1 (PSP-A) (PSPA) (SP-A) (SP-A1) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-4)SFTPA1 COLEC4 PSAP SFTP1 SFTPA SFTPA1BQ8IWL21
Pulmonary surfactant-associated protein C (Fragment)SFTPCE5RHW51
Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D)SFTPD COLEC7 PSPD SFTP4P352471
Purine nucleoside phosphorylase (Fragment)PNPG3V2H31
Purkinje cell protein 4-like protein 1 (PCP4-like protein 1)PCP4L1 IQM1A6NKN81
Puromycin-sensitive aminopeptidase (Fragment)NPEPPSH0YCQ51
Puromycin-sensitive aminopeptidase (Fragment)NPEPPSE9PP111
Putative 3-phosphoinositide-dependent protein kinase 2 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 2 pseudogene)PDPK2P PDPK2Q6A1A21
Putative ADP-ribosylation factor-like protein 5C (ADP-ribosylation factor-like protein 12)ARL5C ARL12A6NH571
Putative aldo-keto reductase family 1 member C8 (Aldo-keto reductase family 1 member C-like protein 1) (EC 1.1.1.-)AKR1C8P AKR1CL1Q5T2L21
Putative apolipoprotein(a)-like protein 2 (Apo(a)-like protein 2) (Lp(a)-liker protein 2) (Apolipoprotein a-related gene C protein) (Apo(a)rg-C)LPAL2 APOARGCQ166091
Putative aspartate aminotransferase, cytoplasmic 2 (EC 2.6.1.-) (Glutamate oxaloacetate transaminase 1-like protein 1) (Transaminase A-like protein 1)GOT1L1Q8NHS21
Putative ATP-binding cassette sub-family C member 13ABCC13 C21orf73 PRED6Q9NSE71
Putative ATP-dependent RNA helicase DDX11-like protein 8 (EC 3.6.4.13) (DEAD/H box protein 11-like 8)DDX11L8A8MPP11
Putative ATP-dependent RNA helicase DHX30DHX30F6R0H41
Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)TDRD12 ECAT8Q587J71
Putative ATP-dependent RNA helicase TDRD9 (Fragment)TDRD9H0YJJ21
Putative cytochrome P450 2D7 (EC 1.14.14.1)CYP2D7Q6XP501
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