EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Receptor-type tyrosine-protein phosphatase SPTPRSG8JL961
Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho)PTPRT KIAA0283O145221
Reelin (EC 3.4.21.-)RELNQ9UDQ21
Regulating synaptic membrane exocytosis protein 1 (Fragment)RIMS1E5RGM01
Regulating synaptic membrane exocytosis protein 4 (RIM4 gamma) (Rab3-interacting molecule 4) (RIM 4)RIMS4 C20orf190Q9H4261
Regulation of nuclear pre-mRNA domain-containing protein 1A (Fragment)RPRD1AK7EP821
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)RCC1 CHC1Q162691
Regulator of chromosome condensation (Fragment)RCC1C9JW691
Regulator of G-protein signaling 12 (RGS12)RGS12O149241
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)RGS2 G0S8 GIG31P412201
Regulator of G-protein signaling 21 (RGS21)RGS21Q2M5E41
Regulator of G-protein signaling 22 (RGS22)RGS22Q8NE091
Regulator of G-protein signaling 3 (RGP3) (RGS3)RGS3P497961
Regulator of G-protein signaling 5 (RGS5)RGS5O155391
Regulator of G-protein signaling 8 (RGS8)RGS8P577711
Regulator of G-protein signaling 9 (RGS9)RGS9O759161
Regulator of G-protein signaling protein-likeRGSL1 RGSL RGSL2A5PLK61
Regulator of G-protein-signaling 6 (cDNA FLJ53896, highly similar to Regulator of G-protein signaling 6)RGS6B7Z7N51
Regulator of G-protein-signaling 7 (Fragment)RGS7Q5T3H51
Regulator of microtubule dynamics protein 1 (Fragment)RMDN1H0YAP51
Regulator of microtubule dynamics protein 2 (RMD-2) (hRMD-2) (Protein FAM82A1)RMDN2 FAM82A FAM82A1 BLOCK18 UNQ9371/PRO34163Q96LZ71
Regulator of microtubule dynamics protein 3 (Fragment)RMDN3H0YLG51
Regulator of telomere elongation helicase 1 (EC 3.6.4.12)RTEL1-TNFRSF6B RTEL1D6RA961
Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like)RTEL1 C20orf41 KIAA1088 NHLQ9NZ711
Regulatory myosin light chain long version0Q71U021
Regulatory-associated protein of mTOR (Fragment)RPTORI3L4361
RelA-associated inhibitor (Fragment)PPP1R13LK7ENG61
Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2)RXFP2 GPR106 GREAT LGR8Q8WXD01
Relaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4)RXFP4 GPR100 RLN3R2Q8TDU91
RELT-like protein 1 (Fragment)RELL1D6RBN91
RELT-like protein 2RELL2 C5orf16 UNQ9423/PRO34565Q8NC241
Remodeling and spacing factor 1 (Fragment)RSF1H7C3061
Replication factor C 5 isoform 1 variant (Fragment)0Q59GW71
Replication factor C subunit 2RFC2A0A087WVY31
Replication factor C subunit 2 (Fragment)RFC2H7C5P41
Replication factor C subunit 2 (Fragment)RFC2H7C5A01
Replication factor C subunit 2 (Fragment)RFC2H7C5961
Replication factor C subunit 4 (Fragment)RFC4C9J8M31
Replication protein A 32 kDa subunit (Fragment)RPA2Q5TEJ01
Replication protein A 70 kDa DNA-binding subunit (Fragment)RPA1I3L4R81
Reprimo-like proteinRPRMLQ8N4K41
Repulsive guidance molecule ARGMAA0A0A0MTQ41
Repulsive guidance molecule A (RGM domain family member A)RGMA RGMQ96B861
RER1 proteinRER1Q6IBJ71
Ret finger protein-like 2 (RING finger protein 79)RFPL2 RNF79O756781
RetbindinRTBDNQ9BSG51
Reticulon0B7Z8W81
Reticulon0B7Z3E31
Reticulon (Fragment)RTN4H7C1061
Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)RTN4 KIAA0886 NOGO My043 SP1507Q7L7Q51
Reticulophagy regulator 3RETREG3K7ENZ61
Retinal dehydrogenase 2ALDH1A2H0YMG71
Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (Rod outer segment membrane guanylate cyclase) (ROS-GC)GUCY2D CORD6 GUC1A4 GUC2D RETGC RETGC1Q028461
Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)GUCY2F GUC2F RETGC2P518411
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma) (EC 3.1.4.35)PDE6G PDEGP185451
Retinitis pigmentosa 1-like 1 proteinRP1L1A6NKC61
Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)RBL1P287491
Retinoic acid early transcript 1G protein (UL-16 binding protein 5) (ULBP5)RAET1GQ6H3X31
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)RARA NR1B1P102761
Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)RXRA NR2B1P197931
Retinoid-binding protein 7 (Retinol binding protein 7, cellular, isoform CRA_a)RBP7 hCG_1820860B1AQ601
Retinol binding protein 1, cellular (Retinol-binding protein 1)RBP1 hCG_16055A0A0A0MQT01
Retinol dehydrogenase 11 (Fragment)RDH11G3V2G61
Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase) (Short chain dehydrogenase/reductase family 7C member 2)RDH12 SDR7C2Q96NR81
Retinol-binding protein 1RBP1A0A0A0MTB91
Retinol-binding protein 4 (Plasma retinol-binding protein) (PRBP) (RBP) [Cleaved into: Plasma retinol-binding protein(1-182); Plasma retinol-binding protein(1-181); Plasma retinol-binding protein(1-179); Plasma retinol-binding protein(1-176)]RBP4 PRO2222Q5VY241
RFC5 protein (Fragment)RFC5Q6LES91
RGR protein (RPE-retinal G protein-coupled receptor) (Retinal G protein coupled receptor, isoform CRA_b)RGR hCG_20085Q96HT61
Rheumatoid factor light chain variable region (Fragment)0A2NW981
Rheumatoid factor RF-ET13 (Fragment)0O432341
Rheumatoid factor RF-ET6 (Fragment)0A2J1N51
Rheumatoid factor RF-IP14 (Fragment)0A2J1N01
Rheumatoid factor RF-IP18 (Fragment)0A2J1N21
Rho GDP-dissociation inhibitor 1ARHGDIAJ3KRE21
Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha)ARHGDIA GDIA1A8MXW01
Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha)ARHGDIA GDIA1B4DUV91
Rho GTPase-activating protein 1 (Fragment)ARHGAP1H0YE291
Rho GTPase-activating protein 1 (Fragment)ARHGAP1E9PNR61
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)ARHGAP11A KIAA0013Q6P4F71
Rho GTPase-activating protein 17ARHGAP17I3L1S91
Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP)ARHGAP24 FILGAPQ8N2641
Rho GTPase-activating protein 25ARHGAP25C9JB561
Rho GTPase-activating protein 26 (Fragment)ARHGAP26F8W8N51
Rho GTPase-activating protein 26 (Fragment)ARHGAP26H7BZE11
Rho GTPase-activating protein 26 (Fragment)ARHGAP26H7C2051
Rho GTPase-activating protein 27ARHGAP27A0A0C4DGE61
Rho GTPase-activating protein 32 (Rho GTPase-activating protein, isoform CRA_b)ARHGAP32 RICS hCG_2042955G3V1741
Rho GTPase-activating protein 40 (Fragment)ARHGAP40H0Y3971
Rho GTPase-activating protein 40 (Rho-type GTPase-activating protein 40)ARHGAP40 C20orf95Q5TG301
Rho GTPase-activating protein 44ARHGAP44F5H6L31
Rho GTPase-activating protein SYDE1 (Fragment)SYDE1M0R1011
Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1)SYDE1Q6ZW311
Rho guanine nucleotide exchange factor 1 (115 kDa guanine nucleotide exchange factor) (p115-RhoGEF) (p115RhoGEF) (Sub1.5)ARHGEF1Q6NX521
Rho guanine nucleotide exchange factor 1 (Fragment)ARHGEF1M0QXV61
Rho guanine nucleotide exchange factor 10-like proteinARHGEF10LQ5VXI41
Rho guanine nucleotide exchange factor 15 (Ephexin-5) (E5) (Vsm-RhoGEF)ARHGEF15 KIAA0915O949891
Rho guanine nucleotide exchange factor 2 (Fragment)ARHGEF2V9GZ141
Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN)ARHGEF3Q9NR811
Rho guanine nucleotide exchange factor 33ARHGEF33A8MVX01
Rho-related GTP-binding protein RhoF (Fragment)RHOFF5GXB11
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