EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Solute carrier family 13 member 3 (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (hNaDC3) (Sodium-dependent high-affinity dicarboxylate transporter 2)SLC13A3 NADC3 SDCT2F6WI181
Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT-1) (NaS2)SLC13A4 SUT1Q9UKG41
Solute carrier family 15 member 3 (Osteoclast transporter) (Peptide transporter 3) (Peptide/histidine transporter 2)SLC15A3 OCTP PHT2 PTR3Q8IY341
Solute carrier family 2 (Facilitated glucose transporter), member 11SLC2A11Q504W21
Solute carrier family 2, facilitated glucose transporter member 14 (Fragment)SLC2A14F5H3J01
Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4)SLC2A4 GLUT4P146721
Solute carrier family 22 member 1SLC22A1F5H5P31
Solute carrier family 22 member 14 (Organic cation transporter-like 4) (ORCTL-4)SLC22A14 OCTL2 ORCTL4Q9Y2671
Solute carrier family 22 member 16 (Carnitine transporter 2) (CT2) (Fly-like putative transporter 2) (FLIPT2) (Flipt 2) (Organic cation transporter OKB1) (Organic cation/carnitine transporter 6)SLC22A16 OCT6Q86VW11
Solute carrier family 22 member 20 (Organic anion transporter 6) (Solute carrier family 22 member 20 pseudogene)SLC22A20P OAT6 SLC22A20A6NK971
Solute carrier family 22 member 25 (Organic anion transporter UST6)SLC22A25 UST6Q6T4231
Solute carrier family 22 member 5 (Fragment)SLC22A5H7C1R81
Solute carrier family 22 member 7 (Novel liver transporter) (Organic anion transporter 2) (hOAT2)SLC22A7 NLT OAT2Q9Y6941
Solute carrier family 23 member 2 (Fragment)SLC23A2H0Y5441
Solute carrier family 25 member 36SLC25A36D6RB261
Solute carrier family 25 member 39 (Fragment)SLC25A39K7EQS81
Solute carrier family 26 member 6 (Solute carrier family 26, member 6, isoform CRA_i)SLC26A6 hCG_1999608G3XAC11
Solute carrier family 27 (Fatty acid transporter), member 2, isoform CRA_b (Very long-chain acyl-CoA synthetase)SLC27A2 hCG_39815G3V1R71
Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3)SLC28A3 CNT3B4E2S81
Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein)SLC35C2 C20orf5 OVCOV1 CGI-15Q9NQQ71
Solute carrier family 35 member E1 (Fragment)SLC35E1C9JK451
Solute carrier family 35 member F1SLC35F1 C6orf169Q5T1Q41
Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3)SLC35F5 NS5ATP3 UNQ2545/PRO6097Q8WV831
Solute carrier family 41 member 3SLC41A3Q96GZ61
Solute carrier family 43 member 3 (Protein FOAP-13)SLC43A3 PSEC0252E7EQD21
Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein)SLC45A3 PCANAP6 PRSTQ96JT21
Solute carrier family 45 member 4SLC45A4 KIAA1126Q5BKX61
Solute carrier family 52, riboflavin transporter, member 2SLC52A2E9PJC11
Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2)SLCO2A1 OATP2A1 SLC21A2Q929591
Solute carrier organic anion transporter family member 2B1 (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2) (Solute carrier family 21 member 9)SLCO2B1 KIAA0880 OATP2B1 OATPB SLC21A9O949561
Somatoliberin (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin)GHRH GHRFP012861
Son of sevenless homolog 1 (Son of sevenless homolog 1 (Drosophila), isoform CRA_d)SOS1 hCG_1641052G5E9C81
Sorbin and SH3 domain-containing protein 1 (Fragment)SORBS1S4R4061
Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)SORDB7Z3A61
Sororin (Cell division cycle-associated protein 5) (p35)CDCA5Q96FF91
Sortilin0A8KAQ31
Sorting nexinSNX6 hCG_2013610A0A0A0MRI21
Sorting nexin 13SNX13Q86XC41
Sorting nexin-10SNX10Q9Y5X01
Sorting nexin-11 (Fragment)SNX11J3QRB91
Sorting nexin-14SNX14D6REK11
Sorting nexin-14 (Fragment)SNX14D6RJG91
Sorting nexin-16SNX16P577681
Sorting nexin-17SNX17 KIAA0064Q6IAS31
Sorting nexin-18 (SH3 and PX domain-containing protein 3B) (Sorting nexin-associated Golgi protein 1)SNX18 SH3PXD3B SNAG1H7BXX31
Sorting nexin-20 (Selectin ligand-interactor cytoplasmic 1) (SLIC-1)SNX20 SLIC1Q7Z6141
Sorting nexin-4 (Fragment)SNX4F8W9T31
Sorting nexin-7SNX7E9PLE11
Sorting nexin-7 (Fragment)SNX7B7ZC831
SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1)NABP2 OBFC2B SSB1 LP3587Q9BQ151
SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1)INIP C9orf80 SSBIP1 HSPC043 HSPC291Q9NRY21
Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110)SP110Q9HB581
SPARC-related modular calcium-binding protein 2 (Fragment)SMOC2H0Y3J41
Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (Testican) 1, isoform CRA_aSPOCK1 hCG_39479D3DQB31
Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52)TUT1 RBM21Q9H6E51
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)SPTBN4 KIAA1642 SPTBN3E9PGQ51
Speedy protein E4SPDYE4A6NLX31
Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)SPATC1L C21orf56Q9H0A91
Sperm equatorial segment protein 1 (ESP) (Equatorial segment protein) (SP-ESP) (Glycosylated 38 kDa sperm protein C-7/8)SPESP1 UNQ732/PRO1418Q6UW491
Sperm flagellar protein 1SPEF1 C20orf28Q9Y4P91
Sperm protein associated with the nucleus on the X chromosome N5 (Nuclear-associated protein SPAN-Xn5) (SPANX-N5) (SPANX family member N5)SPANXN5Q5MJ071
Sperm surface protein Sp17 (Cancer/testis antigen 22) (CT22) (Sp17-1) (Sperm autoantigenic protein 17) (Sperm protein 17)SPA17 SP17Q155061
Sperm-associated antigen 11A (Human epididymis-specific protein 2) (He2) (Protein EP2) (Sperm antigen HE2)SPAG11A EP2 HE2Q6PDA71
Spermatid-specific linker histone H1-like proteinHILS1P600081
Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)SPATA13Q96N961
Spermatogenesis-associated protein 16 (Testis development protein NYD-SP12)SPATA16Q9BXB71
Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1)SPATA2 KIAA0757 PD1Q9UM821
Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411)SPATA20Q8TB221
Spermatogenesis-associated protein 31A1 (Protein FAM75A1)SPATA31A1 C9orf36 FAM75A1 FAM75A2 SPATA31A2Q5TZJ51
Spermatogenesis-associated protein 31A6 (Protein FAM75A6)SPATA31A6 FAM75A6Q5VVP11
Spermatogenesis-associated protein 31E1 (Protein FAM75E1)SPATA31E1 C9orf79 FAM75E1Q6ZUB11
Spermatogenesis-associated protein 32SPATA32K7EQM91
Spermatogenesis-associated protein 32 (Testis-expressed protein 34)SPATA32 C17orf46 TEX34Q96LK81
Spermatogenesis-associated protein 33SPATA33A0A087WYH01
Spermatogenesis-associated protein 33 (Fragment)SPATA33J3KS001
Spermatogenesis-associated protein 4 (Testis and spermatogenesis cell-related protein 2) (Testis spermatocyte apoptosis-related gene 2 protein)SPATA4 TSARG2Q8NEY31
Spermatogenesis-associated protein 9 (Testis development protein NYD-SP16)SPATA9Q9BWV21
Spermatogenesis-associated serine-rich protein 2SPATS2F8VS101
Spermatogenesis-defective protein 39 homologVIPAS39G3V4K31
Spermidine synthaseSRMK7EKM41
Spermine oxidase (EC 1.5.3.16) (Polyamine oxidase 1) (PAO-1) (PAOh1)SMOX C20orf16 SMO UNQ3039/PRO9854Q9NWM01
Sphingomyelin phosphodiesterase 30Q1ZYL91
Sphingomyelin phosphodiesterase 4 (Fragment)SMPD4C9J6471
Sphingosine kinase 2SPHK2M0R0E91
Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91)SPHK2Q9NRA01
Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein)SPICE1 CCDC52 SPICEQ8N0Z31
Spindle and centriole-associated protein 1 (Fragment)SPICE1H7C5N41
Spindle and kinetochore-associated protein 1SKA1 C18orf24Q96BD81
Spindle and kinetochore-associated protein 3SKA3 C13orf3 RAMA1Q8IX901
Spindlin-4SPIN4Q56A731
Spliceosome RNA helicase DDX39B (Fragment)DDX39BH0Y4001
Splicing factor 1 (Fragment)SF1C9J7921
Splicing factor 3B subunit 1 (Fragment)SF3B1H7C3411
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)SF3B1 SAP155E9PCH31
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)U2AF2 U2AF65Q96HC51
Splicing factor, arginine/serine-rich 12 variant (Fragment)0Q59EW71
Splicing factor, proline- and glutamine-rich (Fragment)SFPQH0Y9K71
Splicing factor, proline- and glutamine-rich (Fragment)SFPQH0Y9U21
Splicing regulatory glutamine/lysine-rich protein 1SREK1A0A087WY031
SPRY domain-containing SOCS box protein 4 (SSB-4)SPSB4 SSB4Q96A441
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