EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Squalene synthaseFDFT1E9PS691
Squalene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase)FDFT1B3KQ951
Squamous cell carcinoma antigen 2SERPINB4Q86W051
Squamous cell carcinoma antigen recognized by T-cells 3 (Fragment)SART3F8VV041
SRA stem-loop-interacting RNA-binding protein, mitochondrial (Fragment)SLIRPH0YJ401
SRPR proteinSRPRQ6IAX91
SRR1-like protein (SRR1 domain-containing protein)SRRD SRR1LQ9UH361
SRSF protein kinase 2 (Fragment)SRPK2H7C5L61
Stabilizer of axonemal microtubules 1SAXO1 C9orf138 FAM154AQ8IYX71
STAG3-like protein 3 (Stromal antigen 3-like protein 3)STAG3L3Q7L5M51
STAGA complex 65 subunit gamma (Adenocarcinoma antigen ART1) (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like)SUPT7L KIAA0764O948641
STAM-binding proteinSTAMBPF5H5B91
STAM-binding protein (Fragment)STAMBPC9JEK51
STAM-binding protein (Fragment)STAMBPC9JK831
Stanniocalcin-2 (Fragment)STC2H0YB131
Staphylococcal nuclease domain-containing protein 1 (Fragment)SND1H7C5971
StAR-related lipid transfer protein 13 (46H23.2) (Deleted in liver cancer 2 protein) (DLC-2) (Rho GTPase-activating protein) (START domain-containing protein 13) (StARD13)STARD13 DLC2 GT650Q9Y3M81
StAR-related lipid transfer protein 7, mitochondrial (Fragment)STARD7C9JTD31
STARD3 N-terminal-like protein (Fragment)STARD3NLC9JJ391
START domain-containing protein 10 (Fragment)STARD10F5GWK51
START domain-containing protein 10 (Fragment)STARD10F5H1Z61
StathminSTMN2E5RGX51
StathminSTMN1Q96CE41
Stathmin (Fragment)STMN3A0A0J9YXY41
Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10)STMN2 SCG10 SCGN10G3V1101
STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96)STRADA LYK5 STRADQ7RTN61
STEAP family member 1B (Fragment)STEAP1BC9JL511
Stearoyl-CoA desaturase variant (Fragment)0Q59GX71
Sterile alpha motif domain-containing protein 11 (Fragment)SAMD11H7C3J61
Sterile alpha motif domain-containing protein 3 (SAM domain-containing protein 3)SAMD3Q8N6K71
Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5)SAMD5 SAMDC1Q5TGI41
Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21) (Cytochrome P450-C21B)CYP21A2 CYP21 CYP21BP086861
Steroid 21-hydroxylase (Fragment)CYP21A2E7EN871
Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2]SREBF2 BHLHD2 SREBP2Q127721
Stimulated by retinoic acid gene 6 protein homologSTRA6 PP14296 UNQ3126/PRO10282/PRO19578F5GYI81
Stomatin-like protein 3 (SLP-3)STOML3B4E2851
STON2 protein (Fragment)STON2Q6NT151
Store-operated calcium entry-associated regulatory factorSARAFE5RJV61
Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66)SARAF TMEM66 XTP3 HSPC035 NPD003 PSEC0019 UNQ1967/PRO4499Q96BY91
Storkhead-box protein 1 (Winged-helix domain-containing protein)STOX1 C10orf24Q6ZVD71
Stress-70 protein, mitochondrial (Fragment)HSPA9H0YBG61
Striated muscle preferentially-expressed protein kinase (Fragment)SPEGC9J8D81
Striatin-3STRN3G3V3401
Striatin-4STRN4F5GYK21
Striatin-4 (Fragment)STRN4M0QZM01
Stromal cell-derived factor 2 (Fragment)SDF2K7ELH61
Stromal interaction molecule 2STIM2H0Y8601
Structural maintenance of chromosomes proteinSMC1AG8JLG11
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)SMC3 BAM BMH CSPG6 SMC3L1A8K1561
Structural maintenance of chromosomes protein 4SMC4F8WCB71
Structural maintenance of chromosomes protein 6 (Fragment)SMC6H7C3J81
STXBP1 protein (Syntaxin binding protein 1, isoform CRA_a)stxbp1 STXBP1 hCG_17280Q68CM61
Succinate dehydrogenase assembly factor 2, mitochondrialSDHAF2M0QY911
Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2)SDHAF2 C11orf79 PGL2 SDH5Q9NX181
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1)0B4DYN51
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp)SDHA SDH2 SDHFQ8IW481
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (Fragment)SDHAH0Y8X11
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (Fragment)SDHAH0Y8S21
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Fragment)SDHBA0A087WWT11
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)SUCLA2E5KS601
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (Fragment)SUCLA2Q5T9Q51
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (Fragment)SUCLG2H0Y8521
Succinate-semialdehyde dehydrogenase, mitochondrialALDH5A1C9J8Q51
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 2A) (Testis-specific succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-t)OXCT2 FKSG25Q9BYC21
Sugar phosphate exchanger 3SLC37A3F8WF281
Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)SUMF1 FGE PSEC0152 UNQ3037/PRO9852Q8NBK31
Sulfhydryl oxidase (EC 1.8.3.2)0A8K4C21
Sulfhydryl oxidase (EC 1.8.3.2)GFER hCG_42694H3BQQ41
Sulfhydryl oxidase (EC 1.8.3.2) (Fragment)QSOX2H0Y4301
Sulfide dehydrogenase like (Fragment)0Q53HW71
Sulfotransferase (EC 2.8.2.-)0B7Z2E11
Sulfotransferase (EC 2.8.2.-)SULT1A2E9PKW41
Sulfotransferase (EC 2.8.2.-) (Fragment)SULT1E1H0Y8G01
Sulfotransferase (EC 2.8.2.-) (Fragment)SULT1C2H7C4201
Sulfotransferase (EC 2.8.2.-) (Fragment)SULT1A4 SULT1A3H3BRT01
Sulfotransferase 1C3 (ST1C3) (EC 2.8.2.2)SULT1C3Q6IMI61
Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)SULT1C4 SULT1C2O758971
SUMO-conjugating enzyme (EC 2.3.2.-)0A8K5031
SUN domain-containing protein 3SUN3A0A0A0MSG91
SUN domain-containing protein 3 (Fragment)SUN3H7BZA71
SUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1)SUN3 SUNC1Q8TAQ91
Superoxide dismutase (EC 1.15.1.1)SOD2A0A0C4DFU21
Superoxide dismutase (EC 1.15.1.1) (Fragment)SOD2F5H3C51
Superoxide dismutase (EC 1.15.1.1) (Fragment)SOD2G8JLJ21
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1)SOD1Q167111
Suppression of tumorigenicity 18 proteinST18E5RFE81
Suppression of tumorigenicity 18 protein (Zinc finger protein 387)ST18 KIAA0535 ZNF387O602841
Suppression of tumorigenicity 5 protein (cDNA FLJ55510, highly similar to Suppression of tumorigenicity 5)ST5B4DDL81
Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B) (HeLa tumor suppression 1)ST5 DENND2B HTS1P785241
Suppression of tumorigenicity 5 protein (Fragment)ST5E9PLH61
Suppression of tumorigenicity 5 protein (Fragment)ST5E9PLR21
Suppressor APC domain-containing protein 2 (Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3)SAPCD2 C9orf140Q86UD01
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)SOCS3 CIS3 SSI3O145431
Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)SOCS4 SOCS7Q8WXH51
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)SOCS6 CIS4 SOCS4O145441
Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein)ST14 PRSS14 SNC19 TADG15Q9HB361
Suppressor of tumorigenicity 7 proteinST7E7EMS31
Suppressor of tumorigenicity 7 protein (Protein FAM4A1) (Protein HELG)ST7 FAM4A1 HELG RAY1Q9NRC11
SuprabasinSBSN UNQ698/PRO1343E9PBV31
Surfeit locus protein 2 (Surf-2)SURF2Q155271
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