EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Fragment)UCHL1D6RF531
Ubiquitin carboxyl-terminal hydrolase 10 (Fragment)USP10H3BNS81
Ubiquitin carboxyl-terminal hydrolase 11 (Ubiquitin specific peptidase 11, isoform CRA_b)USP11 hCG_17279G5E9A61
Ubiquitin carboxyl-terminal hydrolase 15 (Fragment)USP15H0YHM41
Ubiquitin carboxyl-terminal hydrolase 17 (USP17) (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 2) (Deubiquitinating protein 3) (DUB-3) (Ubiquitin carboxyl-terminal hydrolase 17-like protein 2) (Ubiquitin thioesterase 17-like protein 2) (Ubiquitin-specific-processing protease 17-like protein 2)USP17L2 DUB3 USP17 USP17H USP17I USP17J USP17K USP17L USP17MQ6R6M41
Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 (EC 3.4.19.12) (Deubiquitinating enzyme 17) (Ubiquitin thioesterase 17) (Ubiquitin-specific-processing protease 17)USP17L24 USP17 USP17H USP17I USP17J USP17K USP17L USP17M; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30Q0WX571
Ubiquitin carboxyl-terminal hydrolase 19USP19E7EST91
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)USP22 KIAA1063 USP3LQ9UPT91
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)USP28 KIAA1515Q96RU21
Ubiquitin carboxyl-terminal hydrolase 28 (Fragment)USP28H0YFT91
Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.4.19.12) (Deubiquitinating enzyme 29) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29)USP29Q9HBJ71
Ubiquitin carboxyl-terminal hydrolase 32 (Fragment)USP32K7EKZ11
Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1) (hVDU1)USP33 KIAA1097 VDU1Q8TEY71
Ubiquitin carboxyl-terminal hydrolase 36USP36E9PEW01
Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)USP36 KIAA1453Q9P2751
Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38)USP38 KIAA1891Q8NB141
Ubiquitin carboxyl-terminal hydrolase 40USP40C9JK141
Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44)USP44Q9H0E71
Ubiquitin carboxyl-terminal hydrolase 44 (Fragment)USP44F8VRW01
Ubiquitin carboxyl-terminal hydrolase 44 (Fragment)USP44F8VVD61
Ubiquitin carboxyl-terminal hydrolase 46USP46H7BZK61
Ubiquitin carboxyl-terminal hydrolase 48 (Fragment)USP48E9PJ871
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)USP49Q70CQ11
Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.4.19.12) (Deubiquitinating enzyme 51) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51)USP51Q70EK91
Ubiquitin carboxyl-terminal hydrolase 7USP7F5H2X11
Ubiquitin carboxyl-terminal hydrolase 7 (Fragment)USP7H3BND81
Ubiquitin carboxyl-terminal hydrolase CYLDCYLDJ3KRR71
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)CYLD CYLD1 KIAA0849 HSPC057Q9NQC71
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Fragment)UCHL3Q5TBK71
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (Fragment)MINDY1H0YJH51
Ubiquitin conjugation factor E4 A (cDNA FLJ51394, highly similar to Ubiquitin conjugation factor E4 A)UBE4AB7Z7P01
Ubiquitin fusion degradation 1 like (Yeast), isoform CRA_b (Ubiquitin fusion degradation 1 protein) (Ubiquitin fusion degradation 1-like)ufd1 UFD1L hCG_17901Q541A51
Ubiquitin specific peptidase 14 (TRNA-guanine transglycosylase), isoform CRA_aUSP14 hCG_1994849D3DUG91
Ubiquitin specific peptidase 4 (Proto-oncogene)USP4Q08AK71
Ubiquitin specific peptidase 9, X-linked, isoform CRA_bUSP9X hCG_18381D3DWB61
Ubiquitin thioesterase (EC 3.4.19.12)DKFZp564E242Q659F91
Ubiquitin-associated protein 2UBAP2F5H2U41
Ubiquitin-associated protein 2-like (Fragment)UBAP2LQ5VU771
Ubiquitin-associated protein 2-like (Protein NICE-4)UBAP2L KIAA0144 NICE4Q9UGL51
Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B)UBE2B RAD6BP631461
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)UBE2C UBCH10A6NP331
Ubiquitin-conjugating enzyme E2 D3UBE2D3D6R9F61
Ubiquitin-conjugating enzyme E2 D3 (Fragment)UBE2D3D6RA111
Ubiquitin-conjugating enzyme E2 H (Fragment)UBE2HH7C4M91
Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)UBE2J2 NCUBE2Q8N2K11
Ubiquitin-conjugating enzyme E2 K (Fragment)UBE2KD6RDM71
Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)UBE2L3 UBCE7 UBCH7B4DDG11
Ubiquitin-conjugating enzyme E2 NUBE2NF8VQQ81
Ubiquitin-conjugating enzyme E2 variant 2 (Fragment)UBE2V2H0YBP91
Ubiquitin-conjugating enzyme E2 variant 2 (Fragment)UBE2V2E5RIF11
Ubiquitin-conjugating enzyme E2 variant 2 (Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_b) (cDNA, FLJ93989, Homo sapiens ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2),mRNA)UBE2V2 hCG_1640505A0M8W41
Ubiquitin-like modifier-activating enzyme 1 (Fragment)UBA1Q5JRR91
Ubiquitin-like modifier-activating enzyme 5 (Fragment)UBA5C9J0F61
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)ATG7 APG7LB4E1701
Ubiquitin-like modifier-activating enzyme ATG7 (Fragment)ATG7H7C0591
Ubiquitin-like protein ISG15 (Fragment)ISG15A0A096LNZ91
Ubiquitin-specific protease 7 isoform (Fragment)0Q6U8A41
Ubiquitinyl hydrolase 1 (EC 3.4.19.12)USP44F8VRI71
UBX domain-containing protein 1UBXN1A0A087WTZ51
UBX domain-containing protein 10 (UBX domain-containing protein 3)UBXN10 UBXD3Q96LJ81
UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37)UBXN2BQ14CS01
UBX domain-containing protein 8 (Fragment)UBXN8A0A087X0J21
UDP-glucose 4-epimerase (Fragment)GALEQ5QPP41
UDP-glucose 4-epimerase (Fragment)GALEQ5QPP11
UDP-glucose 4-epimerase (Fragment)GALEQ5QPP91
UDP-glucose 6-dehydrogenaseUGDHE9PBD21
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22)UGDHB4DN251
UDP-glucose:glycoprotein glucosyltransferase 1UGGT1E2QRN81
UDP-glucose:glycoprotein glucosyltransferase 2UGGT2A6NP031
UDP-glucuronic acid decarboxylase 1 (Fragment)UXS1C9JCB71
UDP-glucuronic acid decarboxylase 1 (Fragment)UXS1C9JE501
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter (UDP-GlcA/UDP-GalNAc transporter) (Solute carrier family 35 member D1) (UDP-galactose transporter-related protein 7) (UGTrel7)SLC35D1 KIAA0260 UGTREL7Q9NTN31
UDP-glucuronosyltransferase 1-4 (UDPGT 1-4) (UGT1*4) (UGT1-04) (UGT1.4) (EC 2.4.1.17) (Bilirubin-specific UDPGT isozyme 2) (hUG-BR2) (UDP-glucuronosyltransferase 1-D) (UGT-1D) (UGT1D) (UDP-glucuronosyltransferase 1A4)UGT1A4 GNT1 UGT1P223101
UDP-glucuronosyltransferase 1-8 (UDPGT 1-8) (UGT1*8) (UGT1-08) (UGT1.8) (EC 2.4.1.17) (UDP-glucuronosyltransferase 1-H) (UGT-1H) (UGT1H) (UDP-glucuronosyltransferase 1A8)UGT1A8 GNT1 UGT1Q9HAW91
UDP-glucuronosyltransferase 2A3 (UDPGT 2A3) (EC 2.4.1.17)UGT2A3 UNQ2559/PRO6239Q6UWM91
UDP-glucuronosyltransferase 3A2 (UDPGT 3A2) (EC 2.4.1.17)UGT3A2 PSEC0073 UNQ842/PRO1780Q3SY771
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Homolog of Fringe connection protein 1) (HFRC1) (SQV7-like protein) (SQV7L) (Solute carrier family 35 member D2) (UDP-galactose transporter-related protein 8) (UGTrel8)SLC35D2 HFRC UGTREL8Q76EJ31
UG0315G030Q8IXG51
UGa8H (Fragment)IGHVA2KUC31
ULIP (Fragment)ULIPQ9NR931
Uncharacterized aarF domain-containing protein kinase 5ADCK5R4GN531
Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)ADCK5Q3MIX31
Uncharacterized membrane protein C3orf80C3orf80F5H4A91
Uncharacterized protein0Q6GMW61
Uncharacterized proteinLOC402299 tcag7.1260A4D1P01
Uncharacterized proteinRP5-1022P6.2 hCG_39118D3DW071
Uncharacterized proteinLOC100996720A0A0D9SF211
Uncharacterized protein0K7EK781
Uncharacterized proteinLOC102723996A0A087X1L81
Uncharacterized protein0F8VWA31
Uncharacterized protein0G3V3181
Uncharacterized protein0F8VNQ11
Uncharacterized protein0M0QZU91
Uncharacterized protein0Q145691
Uncharacterized protein0H0YC421
Uncharacterized protein0M0R2N41
Uncharacterized protein (Fragment)0H0YJ601
Uncharacterized protein (Fragment)LOC81691H3BM721
Uncharacterized protein (Fragment)0H0YIV91
Uncharacterized protein (Fragment)0M0R0L41
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