EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)FOLH1 FOLH NAALAD1 PSM PSMA GIG27Q0460935
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1-L) (EC 1.1.1.8)GPD1L KIAA0089Q8N33535
Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) (p51-nedasin)GDA KIAA1258Q9Y2T335
Hemoglobin subunit epsilon (Epsilon-globin) (Hemoglobin epsilon chain)HBE1 HBEP0210035
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)HMGB3 HMG2A HMG4O1534735
Histone H3.3C (Histone H3.5)H3F3CQ6NXT235
HLA class I histocompatibility antigen, A-11 alpha chain (MHC class I antigen A*11)HLA-A HLAAP1374635
HLA class I histocompatibility antigen, A-30 alpha chain (MHC class I antigen A*30)HLA-A HLAAP1618835
HLA class I histocompatibility antigen, Cw-17 alpha chain (MHC class I antigen Cw*17)HLA-C D6S204 HLA-JY3 HLACQ9560435
Keratin, type I cytoskeletal 28 (Cytokeratin-28) (CK-28) (Keratin-25D) (K25D) (Keratin-28) (K28) (Type I inner root sheath-specific keratin-K25irs4)KRT28 KRT25DQ7Z3Y735
LisH domain-containing protein ARMC9 (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21)ARMC9 KIAA1868Q7Z3E535
Mucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125)MUC16 CA125Q8WXI735
Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)]MUC4Q9910235
Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)MINPP1 MIPP UNQ900/PRO1917Q9UNW135
Neurobeachin-like protein 2NBEAL2 KIAA0540 UNQ253/PRO290Q6ZNJ135
Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP)SIL1 UNQ545/PRO836Q9H17335
Out at first protein homolog (HCV NS5A-transactivated protein 13 target protein 2)OAF NS5ATP13TP2Q86UD135
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)OSBPL8 KIAA1451 ORP8 OSBP10Q9BZF135
Pannexin-1PANX1 MRS1 UNQ2529/PRO6028Q96RD735
Peptidyl-prolyl cis-trans isomerase FKBP10 (PPIase FKBP10) (EC 5.2.1.8) (65 kDa FK506-binding protein) (65 kDa FKBP) (FKBP-65) (FK506-binding protein 10) (FKBP-10) (Immunophilin FKBP65) (Rotamase)FKBP10 FKBP65 PSEC0056Q96AY335
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)PIK3R1 GRB1P2798635
Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)PPCS COABQ9HAB835
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)ATP2B2 PMCA2Q0181435
Proteasome assembly chaperone 3 (PAC-3) (hPAC3)PSMG3 C7orf48 PAC3Q9BT7335
Protein FAM91A1FAM91A1Q658Y435
Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19)PML MYL PP8675 RNF71 TRIM19P2959035
Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)TGM1 KTGP2273535
Putative nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6)NME2P1O6036135
Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30)RGN SMP30Q1549335
Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein)SRGN PRG PRG1P1012435
Serine incorporator 3 (Tumor differentially expressed protein 1)SERINC3 DIFF33 TDE1 SBBI99Q1353035
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)NEK9 KIAA1995 NEK8 NERCCQ8TD1935
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)TBK1 NAKQ9UHD235
Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2)SPPL2A IMP3 PSL2 PSEC0147Q8TCT835
Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-2)ATP1A2 KIAA0778P5099335
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)SUPT5H SPT5 SPT5HO0026735
Transmembrane protease serine 2 (EC 3.4.21.-) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]TMPRSS2 PRSS10O1539335
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)TRMT6 KIAA1153 TRM6 CGI-09Q9UJA535
Ubiquitin-like protein 5UBL5Q9BZL135
Unconventional myosin-Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC)MYO1A MYHLQ9UBC535
V-type proton ATPase 116 kDa subunit a isoform 3 (V-ATPase 116 kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)TCIRG1 ATP6N1C ATP6V0A3Q1348835
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)WDR26 CDW2 MIP2 PRO0852Q9H7D735
60S ribosomal export protein NMD3 (hNMD3)NMD3 CGI-07Q96D4634
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-) (METH-1)ADAMTS1 KIAA1346 METH1Q9UHI834
Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)ACAD9Q9H84534
Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)ADA ADA1P0081334
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)CLPPQ1674034
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)GRK2 ADRBK1 BARK BARK1P2509834
Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]EPHX2P3491334
Biotinidase (Biotinase) (EC 3.5.1.12)BTDP4325134
Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (NADPH oxidase 2) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome)CYBB NOX2P0483934
Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B)DYNC2H1 DHC1B DHC2 DNCH2 DYH1B KIAA1997Q8NCM834
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)DOCK1Q1418534
Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)DNAH6 DNAHC6 DNHL1 HL2 KIAA1697Q9C0G634
Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1)ELP2 STATIP1Q6IA8634
Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2)EXOC6B KIAA0919 SEC15B SEC15L2Q9Y2D434
F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)CARMIL1 CARMIL LRRC16 LRRC16AQ5VZK934
F-box only protein 50 (NCC receptor protein 1 homolog) (NCCRP-1) (Non-specific cytotoxic cell receptor protein 1 homolog)NCCRP1 FBXO50Q6ZVX734
Fibroleukin (Fibrinogen-like protein 2) (pT49)FGL2Q1431434
Glycophorin-C (Glycoconnectin) (Glycophorin-D) (GPD) (Glycoprotein beta) (PAS-2') (Sialoglycoprotein D) (CD antigen CD236)GYPC GLPC GPCP0492134
Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)GOLIM4 GIMPC GOLPH4 GPP130O0046134
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)GIGYF2 KIAA0642 PERQ2 TNRC15Q6Y7W634
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)RABIF MSS4 RASGRF3P4722434
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)GNA12Q0311334
Histone H2A type 1 (H2A.1) (Histone H2A/p)HIST1H2AG H2AFP; HIST1H2AI H2AFC; HIST1H2AK H2AFD; HIST1H2AL H2AFI; HIST1H2AM H2AFNP0C0S834
Histone H2B type 1-H (Histone H2B.j) (H2B/j)HIST1H2BH H2BFJQ9307934
HLA class I histocompatibility antigen, A-33 alpha chain (Aw-19) (Aw-33) (MHC class I antigen A*33)HLA-A HLAAP1619034
HLA class I histocompatibility antigen, B-41 alpha chain (Bw-41) (MHC class I antigen B*41)HLA-B HLABP3047934
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)ROR1 NTRKR1Q0197334
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]INSRP0621334
Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160)AQR KIAA0560O6030634
Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)KRT24 KA24Q2M2I534
Latexin (Endogenous carboxypeptidase inhibitor) (ECI) (Protein MUM) (Tissue carboxypeptidase inhibitor) (TCI)LXNQ9BS4034
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)DBT BCATE2P1118234
m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)DCPS DCS1 HINT5 HSPC015Q96C8634
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)MDC1 KIAA0170 NFBD1Q1467634
Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M)METAP2 MNPEP P67EIF2P5057934
Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL)MGLLQ9968534
Nucleolysin TIAR (TIA-1-related protein)TIAL1Q0108534
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)CPOX CPO CPXP3655134
Phospholipid-transporting ATPase IC (EC 3.6.3.1) (ATPase class I type 8B member 1) (Familial intrahepatic cholestasis type 1) (P4-ATPase flippase complex alpha subunit ATP8B1)ATP8B1 ATPIC FIC1 PFICO4352034
Pleckstrin homology-like domain family A member 2 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein) (Imprinted in placenta and liver protein) (Tumor-suppressing STF cDNA 3 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein) (p17-Beckwith-Wiedemann region 1 C) (p17-BWR1C)PHLDA2 BWR1C HLDA2 IPL TSSC3Q53GA434
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)DDX23Q9BUQ834
Probable palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 20) (DHHC-20)ZDHHC20Q5W0Z934
Prostaglandin-H2 D-isomerase (EC 5.3.99.2) (Beta-trace protein) (Cerebrin-28) (Glutathione-independent PGD synthase) (Lipocalin-type prostaglandin-D synthase) (Prostaglandin-D2 synthase) (PGD2 synthase) (PGDS) (PGDS2)PTGDS PDSP4122234
Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog)HID1 C17orf28 DMC1Q8IV3634
Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A)TMEM167A TMEM167Q8TBQ934
Protein phosphatase 1 regulatory subunit 14B (Phospholipase C-beta-3 neighbouring gene protein)PPP1R14B PLCB3N PNGQ96C9034
Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2)PPM1F KIAA0015 POPX2P4959334
Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1)ARMT1 C6orf211Q9H99334
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)PDHA1 PHE1AP0855934
Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)RAB3GAP1 KIAA0066 RAB3GAPQ1504234
Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7)RANBP9 RANBPMQ96S5934
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)ERBB2 HER2 MLN19 NEU NGLP0462634
Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112)PDS5A KIAA0648 PDS5 PIG54Q29RF734
Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)PDS5B APRIN AS3 KIAA0979Q9NTI534
Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6)UTP20 DRIMO7569134
Stanniocalcin-1 (STC-1)STC1 STCP5282334
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)SVEP1 C9orf13 CCP22 SELOBQ4LDE534
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)TTC9CQ8N5M434
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