EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1)SBF1 MTMR5O9524832
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)WWP2O0030832
Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)NUDT12Q9BQG232
Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP)PLPP3 LPP3 PPAP2BO1449532
Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein) (hPHRP)PTERQ96BW532
PITH domain-containing protein 1PITHD1 C1orf128 AD039 HT014 PP603Q9GZP432
Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence)GBAS NIPSNAP2O7532332
Protein unc-13 homolog D (Munc13-4)UNC13DQ70J9932
Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)FAT2 CDHF8 KIAA0811 MEGF1Q9NYQ832
Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43)PCDHGC3 PCDH2Q9UN7032
Protocadherin-1 (Cadherin-like protein 1) (Protocadherin-42) (PC42)PCDH1Q0817432
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)RASA1 GAP RASAP2093632
Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)RFC5P4093732
SAP domain-containing ribonucleoprotein (Cytokine-induced protein of 29 kDa) (Nuclear protein Hcc-1) (Proliferation-associated cytokine-inducible protein CIP29)SARNP HCC1 HSPC316P8297932
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)SRSF11 SFRS11Q0551932
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]STK3 KRS1 MST2Q1318832
Sodium-dependent phosphate transporter 2 (Gibbon ape leukemia virus receptor 2) (GLVR-2) (Phosphate transporter 2) (PiT-2) (Pit2) (hPit2) (Solute carrier family 20 member 2)SLC20A2 GLVR2 PIT2Q0835732
Solute carrier family 35 member F2SLC35F2Q8IXU632
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)STRN3 GS2NA SG2NAQ1303332
Tensin-3 (Tensin-like SH2 domain-containing protein 1) (Tumor endothelial marker 6)TNS3 TEM6 TENS1 TPPQ68CZ232
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)SMARCA4 BAF190A BRG1 SNF2B SNF2L4P5153232
Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TSPO BZRP MBRP3053632
Transmembrane protein 192TMEM192Q8IY9532
Unconventional myosin-VcMYO5CQ9NQX432
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)RAD23AP5472532
Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome chromosomal region 24 protein)VPS37D WBSCR24Q86XT232
WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80)WDR48 KIAA1449 UAF1Q8TAF332
2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS)OAS3 P/OKcl.4Q9Y6K531
39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27) (Mitochondrial large ribosomal subunit protein bL27m)MRPL27 HSPC250Q9P0M931
5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-)NT5DC1 NT5C2L1 LP2642Q5TFE431
60S ribosomal protein L26-like 1 (Large ribosomal subunit protein uL24-like 1)RPL26L1 RPL26P1Q9UNX331
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase 1) (ADPRC 1) (Cyclic ADP-ribose hydrolase 1) (cADPr hydrolase 1) (T10) (CD antigen CD38)CD38P2890731
Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9)A2ML1 CPAMD9A8K2U031
Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog)CIAPIN1 CUA001 PRO0915Q6FI8131
Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C]ARSAP1528931
ATP-binding cassette sub-family A member 13ABCA13Q86UQ431
ATP-binding cassette sub-family F member 3ABCF3Q9NUQ831
Beta-arrestin-1 (Arrestin beta-1)ARRB1 ARR1P4940731
Bloom syndrome protein (EC 3.6.4.12) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)BLM RECQ2 RECQL3P5413231
C-terminal-binding protein 2 (CtBP2)CTBP2P5654531
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)CAMK2G CAMK CAMK-II CAMKGQ1355531
Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)CEACAM6 NCAP4019931
Cathepsin S (EC 3.4.22.27)CTSSP2577431
cDNA FLJ55673, highly similar to Complement factor B (EC 3.4.21.47)0B4E1Z431
Chitinase domain-containing protein 1 (Stabilin-1-interacting chitinase-like protein) (SI-CLP)CHID1 GL008 PSEC0104 SB139Q9BWS931
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)CLASP1 KIAA0622 MAST1Q7Z46031
Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit)NDUFA4O0048331
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)DCAF7 HAN11 WDR68P6196231
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog)RAD21 HR21 KIAA0078 NXP1O6021631
EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10)EMILIN2Q9BXX031
Fibromodulin (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin)FMOD FM SLRR2EQ0682831
G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)GRK6 GPRK6P4325031
Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein)GLMN FAP48 FAP68 VMGLOMQ9299031
Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230)GOLGA4Q1343931
GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1)GPN1 MBDIN RPAP4 XAB1 HUSSY-23Q9HCN431
Guanylate kinase (EC 2.7.4.8) (GMP kinase)GUK1 GMKQ1677431
Heat shock 70 kDa protein 12AHSPA12A KIAA0417O4330131
Immunoglobulin kappa variable 1-39 (Ig kappa chain V-I region DEE) (Ig kappa chain V-I region Hau) (Ig kappa chain V-I region Mev) (Ig kappa chain V-I region OU) (Ig kappa chain V-I region Walker)IGKV1-39P0159731
Immunoglobulin lambda variable 3-25 (Ig lambda chain V-IV region Hil)IGLV3-25P0171731
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB)IKBKB IKKBO1492031
Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)IGFBP5 IBP5P2459331
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)IFIT5 ISG58 RI58Q1332531
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]MMP1 CLGP0395631
Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)KRT74 K6IRS4 KB37 KRT5C KRT6IRS4Q7RTS731
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)KLC4 KNSL8Q9NSK031
Kinesin-like protein KIF13B (Kinesin-like protein GAKIN)KIF13B GAKIN KIAA0639Q9NQT831
Latent-transforming growth factor beta-binding protein 3 (LTBP-3)LTBP3Q9NS1531
Mammalian ependymin-related protein 1 (MERP-1) (Upregulated in colorectal cancer gene 1 protein)EPDR1 MERP1 UCC1Q9UM2231
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)MARK3 CTAK1 EMK2P2744831
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (EC 6.3.4.3) (Formyltetrahydrofolate synthetase)MTHFD1L FTHFSDC1Q6UB3531
Mth938 domain-containing protein (Adipogenesis associated Mth938 domain-containing protein)AAMDC C11orf67 PTD015Q9H7C931
Multimerin-1 (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4) (Endothelial cell multimerin) [Cleaved into: Platelet glycoprotein Ia*; 155 kDa platelet multimerin (p-155) (p155)]MMRN1 ECM EMILIN4 GPIA* MMRNQ1320131
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (GRIM-19) (Gene associated with retinoic and IFN-induced mortality 19 protein) (NADH-ubiquinone oxidoreductase B16.6 subunit)NDUFA13 GRIM19 CDA016 CGI-39Q9P0J031
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit)NDUFV2P1940431
Nicalin (Nicastrin-like protein)NCLNQ969V331
Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1)UBTF UBF UBF1P1748031
Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)PGAM2 PGAMMP1525931
Phospholipid-transporting ATPase IG (EC 3.6.3.1) (ATPase IQ) (ATPase class VI type 11C) (P4-ATPase flippase complex alpha subunit ATP11C)ATP11C ATPIG ATPIQQ8NB4931
Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3)DDX20 DP103 GEMIN3Q9UHI631
Prolyl endopeptidase FAP (EC 3.4.21.26) (170 kDa melanoma membrane-bound gelatinase) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)]FAPQ1288431
Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Protein FAM213B)FAM213B C1orf93Q8TBF231
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)JAG1 JAGL1P7850431
Protein MAL2MAL2Q969L231
Protein transport protein Sec24D (SEC24-related protein D)SEC24D KIAA0755O9485531
Protein YIPF5 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5) (Smooth muscle cell-associated protein 5) (SMAP-5) (YIP1 family member 5) (YPT-interacting protein 1 A)YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275Q969M331
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)AKT2P3175131
Ras-related GTP-binding protein C (Rag C) (RagC) (GTPase-interacting protein 2) (TIB929)RRAGCQ9HB9031
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)RHOQ ARHQ RASL7A TC10P1708131
RNA-binding protein 3 (RNA-binding motif protein 3) (RNPL)RBM3 RNPLP9817931
RRP12-like proteinRRP12 KIAA0690Q5JTH931
Selenoprotein F (15 kDa selenoprotein)SELENOF SEP15O6061331
Selenoprotein P (SeP)SELENOP SELP SEPP1P4990831
Stanniocalcin-2 (STC-2) (Stanniocalcin-related protein) (STC-related protein) (STCRP)STC2O7606131
Sushi repeat-containing protein SRPX2 (Sushi-repeat protein upregulated in leukemia)SRPX2 SRPULO6068731
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)SMARCC1 BAF155Q9292231
Testis-expressed protein 10TEX10 L18 Nbla10363Q9NXF131
Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1)TTC7B TTC7L1Q86TV631
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)TRIP6 OIP1Q1565431
Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2)TRAPPC1 BET5 MUM2Q9Y5R831
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)SUPT6H KIAA0162 SPT6HQ7KZ8531
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