EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)COX7A2 COX7ALP1440629
DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)DAZAP1Q96EP529
DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3)DCUN1D3 SCCRO3Q8IWE429
Dedicator of cytokinesis protein 2DOCK2 KIAA0209Q9260829
Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase)DCTDP3232129
Disco-interacting protein 2 homolog A (DIP2 homolog A)DIP2A C21orf106 DIP2 KIAA0184Q1468929
Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3)DNAH2 DNAHC2 DNHD3 KIAA1503Q9P22529
Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)DYNLT3 TCTE1L TCTE1XLP5180829
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)TRIP12 KIAA0045 ULFQ1466929
Elongator complex protein 3 (hELP3) (EC 2.3.1.48)ELP3Q9H9T329
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)EPS15L1 EPS15RQ9UBC229
Extracellular matrix protein FRAS1FRAS1 KIAA1500Q86XX429
Fermitin family homolog 1 (Kindlerin) (Kindlin syndrome protein) (Kindlin-1) (Unc-112-related protein 1)FERMT1 C20orf42 KIND1 URP1Q9BQL629
FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL)FKBP15 KIAA0674Q5T1M529
Galectin-related protein (Lectin galactoside-binding-like protein)LGALSL GRP HSPC159Q3ZCW229
Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein)GJC1 GJA7P3638329
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)GSK3AP4984029
Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Secreted glypican-3]GPC3 OCI5P5165429
Histone H1t (Testicular H1 histone)HIST1H1T H1FT H1TP2249229
Histone H2B type 1-D (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)HIST1H2BD H2BFB HIRIP2P5887629
HLA class I histocompatibility antigen, B-54 alpha chain (Bw-22) (Bw-54) (MHC class I antigen B*54)HLA-B HLABP3049229
HLA class I histocompatibility antigen, Cw-6 alpha chain (MHC class I antigen Cw*6)HLA-C HLACQ2996329
Immunoglobulin heavy variable 1-46 (Ig heavy chain V-I region DOT) (Ig heavy chain V-I region HG3) (Ig heavy chain V-I region Mot)IGHV1-46P0174329
Immunoglobulin kappa variable 2D-28 (Ig kappa chain V-II region FR) (Ig kappa chain V-II region GM607) (Ig kappa chain V-II region MIL) (Ig kappa chain V-II region TEW)IGKV2D-28P0161529
Immunoglobulin kappa variable 3-20 (Ig kappa chain V-III region B6) (Ig kappa chain V-III region GOL) (Ig kappa chain V-III region HAH) (Ig kappa chain V-III region HIC) (Ig kappa chain V-III region IARC/BL41) (Ig kappa chain V-III region NG9) (Ig kappa chain V-III region SIE) (Ig kappa chain V-III region Ti) (Ig kappa chain V-III region WOL)IGKV3-20P0162129
Keratin, type II cuticular Hb6 (Hair keratin K2.11) (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26)KRT86 KRTHB6O4379029
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)BRCC3 BRCC36 C6.1A CXorf53P4673629
Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32)MMGT1 EMC5 TMEM32Q8N4V129
Mitochondrial import inner membrane translocase subunit Tim9TIMM9 TIM9 TIM9A TIMM9AQ9Y5J729
mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)RAE1 MRNP41P7840629
Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]MYLK MLCK MLCK1 MYLK1Q1574629
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)ELANE ELA2P0824629
Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133)NUP133Q8WUM029
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)NUP43Q8NFH329
Overexpressed in colon carcinoma 1 protein (OCC-1) (AGD3)OCC1 C12orf75Q8TAD729
Palladin (SIH002) (Sarcoma antigen NY-SAR-77)PALLD KIAA0992 CGI-151Q8WX9329
PCI domain-containing protein 2 (CSN12-like protein)PCID2 HT004Q5JVF329
PDZK1-interacting protein 1 (17 kDa membrane-associated protein) (Protein DD96)PDZK1IP1 MAP17Q1311329
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)PIK3C2AO0044329
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)PIP4K2B PIP5K2BP7835629
Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2)PCOLCE2 PCPE2 UNQ250/PRO287Q9UKZ929
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)AGO2 EIF2C2Q9UKV829
Protein EVI2B (Ecotropic viral integration site 2B protein homolog) (EVI-2B) (CD antigen CD361)EVI2B EVDBP3491029
Protein numb homolog (h-Numb) (Protein S171)NUMBP4975729
Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA)PPM1A PPPM1AP3581329
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)SON C21orf50 DBP5 KIAA1019 NREBP HSPC310 HSPC312P1858329
Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)SERPINA10 ZPI UNQ707/PRO1358Q9UK5529
Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase)LOXP2830029
Putative deoxyribonuclease TATDN1 (EC 3.1.21.-) (Hepatocarcinoma high expression protein)TATDN1 CDA11Q6P1N929
Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B)HSPA7 HSP70BP4874129
Putative Ras-related protein Rab-1C (hRab1c)RAB1CQ9292829
Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B)RMDN1 FAM82B CGI-90Q96DB529
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3Q5H9R729
Sialate O-acetylesterase (EC 3.1.1.53) (H-Lse) (Sialic acid-specific 9-O-acetylesterase)SIAE YSG2Q9HAT229
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)SNRPN HCERN3 SMNP6316229
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (SWI/SNF complex 60 kDa subunit)SMARCD1 BAF60AQ96GM529
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)SNAP25 SNAPP6088029
Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4)TENM4 KIAA1302 ODZ4 TNM4Q6N02229
Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9)ASPSCR1 ASPL RCC17 TUG UBXD9 UBXN9Q9BZE929
Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)TYMS TS OK/SW-cl.29P0481829
Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit)SUPT4H1 SPT4H SUPT4HP6327229
Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)TRPV2 VRLQ9Y5S129
TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)TRIOBP KIAA1662 TARA HRIHFB2122Q9H2D629
Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)BAZ1B WBSC10 WBSCR10 WBSCR9 WSTFQ9UIG029
U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31)PRPF31 PRP31Q8WWY329
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6)COQ6 CGI-10Q9Y2Z929
Uncharacterized protein C10orf67, mitochondrialC10orf67 LINC01552Q8IYJ229
Vitamin K-dependent protein ZPROZP2289129
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]ACE2 UNQ868/PRO1885Q9BYF128
Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)ATL2 ARL6IP2Q8NHH928
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2)ARFGEF2 ARFGEP2 BIG2Q9Y6D528
C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa)C2CD5 CDP138 KIAA0528Q86YS728
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)CENPFP4945428
Chloride intracellular channel protein 6 (Parchorin)CLIC6 CLIC1LQ96NY728
Cleft lip and palate transmembrane protein 1CLPTM1O9600528
Copine-5 (Copine V)CPNE5 KIAA1599Q9HCH328
Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)CDK6 CDKN6Q0053428
Diphosphoinositol polyphosphate phosphohydrolase 2 (DIPP-2) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4)NUDT4 DIPP2 KIAA0487 HDCMB47PQ9NZJ928
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)LRSAM1 TAL UNQ6496/PRO21356Q6UWE028
Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)SLC4A8 KIAA0739 NBC NBC3 NDCBE1Q2Y0W828
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)GFM1 EFG EFG1 GFMQ96RP928
Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A)EFL1 EFTUD1 FAM42AQ7Z2Z228
Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)EFNB2 EPLG5 HTKL LERK5P5279928
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)IFI16 IFNGIP1Q1666628
HBS1-like protein (ERFS)HBS1L HBS1 KIAA1038Q9Y45028
HLA class I histocompatibility antigen, B-58 alpha chain (Bw-58) (MHC class I antigen B*58)HLA-B HLABP1031928
HLA class I histocompatibility antigen, Cw-3 alpha chain (MHC class I antigen Cw*3)HLA-C HLACP0422228
Hyaluronan and proteoglycan link protein 1 (Cartilage-linking protein 1) (Cartilage-link protein) (Proteoglycan link protein)HAPLN1 CRTL1P1091528
Immunoglobulin lambda constant 7 (Ig lambda-7 chain C region)IGLC7A0M8Q628
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)IFIT3 CIG-49 IFI60 IFIT4 ISG60O1487928
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]MST1R PTK8 RONQ0491228
Multimerin-2 (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit)MMRN2 EMILIN3Q9H8L628
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)MBPP0268628
Myelin protein zero-like protein 2 (Epithelial V-like antigen 1)MPZL2 EVA EVA1 UNQ606/PRO1192O6048728
N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase)GALNSP3405928
N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase)SCYL1 CVAK90 GKLP NTKL TAPK TEIF TRAP HT019Q96KG928
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit)NDUFA2O4367828
Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)NUP210 KIAA0906 PSEC0245Q8TEM128
Nucleoporin SEH1 (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)SEH1L SEC13L SEH1Q96EE328
OCIA domain-containing protein 2 (Ovarian carcinoma immunoreactive antigen-like protein)OCIAD2Q56VL328
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