EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)S100A2 S100LP2903426
Protein tweety homolog 2 (hTTY2)TTYH2 C17orf29Q9BSA426
Pseudouridylate synthase 7 homolog (EC 5.4.99.-)PUS7 KIAA1897Q96PZ026
Putative heat shock protein HSP 90-beta 4HSP90AB4PQ58FF626
Putative ubiquitin-conjugating enzyme E2 N-like (Epididymis tissue protein Li 174)UBE2NLQ5JXB226
Pyridoxal phosphate phosphatase (PLP phosphatase) (EC 3.1.3.3) (EC 3.1.3.74) (Chronophin)PDXP CIN PLP PLPPQ96GD026
RELT-like protein 1RELL1 PSEC0162Q8IUW526
Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)RSF1 HBXAP XAP8Q96T2326
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314Q1415526
Secretogranin-2 (Chromogranin-C) (Secretogranin II) (SgII) [Cleaved into: Secretoneurin (SN); Manserin]SCG2 CHGCP1352126
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)STK25 SOK1 YSK1O0050626
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)STK38 NDR1Q1520826
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)PPP6R1 KIAA1115 PP6R1 SAPS1Q9UPN726
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)SERPINB4 PI11 SCCA2P4859426
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)SERPINB8 PI8P5045226
Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)SLC34A2O9543626
Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3)SLC23A1 SVCT1 YSPL3Q9UHI726
Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Nucleobase transporter-like 1 protein) (Sodium-dependent vitamin C transporter 2) (hSVCT2) (Yolk sac permease-like molecule 2)SLC23A2 KIAA0238 NBTL1 SLC23A1 SVCT2 YSPL2Q9UGH326
Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin)SPON2 DIL1 UNQ435/PRO866Q9BUD626
SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein) (CLL deletion region gene 6 protein)SPRYD7 C13orf1 CLLD6Q5W11126
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)TAF15 RBP56 TAF2NQ9280426
Tax1-binding protein 1 (TRAF6-binding protein)TAX1BP1 T6BP PRO0105Q86VP126
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1TSTD1 KATQ8NFU326
THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90)THOC5 C22orf19 KIAA0983Q1376926
Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150)TCERG1 CA150 TAF2SO1477626
Transmembrane protein 132A (HSPA5-binding protein 1)TMEM132A HSPA5BP1 KIAA1583Q24JP526
Transmembrane protein 87ATMEM87A PSEC0094Q8NBN326
Uncharacterized protein KIAA1522KIAA1522Q9P20626
Uroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa)UPK1A TSPAN21O0032226
Uveal autoantigen with coiled-coil domains and ankyrin repeatsUACA KIAA1561Q9BZF926
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106)VCAM1P1932026
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1)PLCB1 KIAA0581Q9NQ6625
28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt) (Mitochondrial small ribosomal subunit protein mS27)MRPS27 KIAA0264Q9255225
39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1) (Mitochondrial large ribosomal subunit protein uL1m)MRPL1 BM-022Q9BYD625
39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Mitochondrial large ribosomal subunit protein uL23m) (Ribosomal protein L23-like)MRPL23 L23MRP RPL23LQ1654025
40S ribosomal protein S30 (Small ribosomal subunit protein eS30)FAUP6286125
60S ribosomal protein L22-like 1 (Large ribosomal subunit protein eL22-like 1)RPL22L1Q6P5R625
Adseverin (Scinderin)SCIN KIAA1905Q9Y6U325
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)ANAPC1 TSG24Q9H1A425
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)LFNGQ8NES325
Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase)MANBA MANB1O0046225
Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3)ABCC3 CMOAT2 MLP2 MRP3O1543825
Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)CA9 G250 MNQ1679025
CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27)CDK5RAP3 IC53 LZAP MSTP016 OK/SW-cl.114 PP1553Q96JB525
COMM domain-containing protein 2COMMD2 HSPC042 My004Q86X8325
Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1)COG1 KIAA1381 LDLBQ8WTW325
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56) (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa)COA3 CCDC56 MITRAC12 HSPC009Q9Y2R025
Cytochrome c oxidase copper chaperoneCOX17Q1406125
Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1)DHCR24 KIAA0018Q1539225
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)DDR2 NTRKR3 TKT TYRO10Q1683225
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)POLR1DQ9Y2S025
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde)ENPP6 UNQ1889/PRO4334Q6UWR725
EH domain-binding protein 1-like protein 1EHBP1L1Q8N3D425
Endophilin-B2 (SH3 domain-containing GRB2-like protein B2)SH3GLB2 KIAA1848 PP578Q9NR4625
Equilibrative nucleoside transporter 2 (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Hydrophobic nucleolar protein, 36 kDa) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2)SLC29A2 DER12 ENT2 HNP36Q1454225
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)EXOSC5 CML28 RRP46Q9NQT425
Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-)SULF2 KIAA1247 UNQ559/PRO1120Q8IWU525
EzrinEZRE7EQR425
F-box only protein 2FBXO2 FBX2Q9UK2225
FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1)FHOD1 FHOS FHOS1Q9Y61325
Follistatin (FS) (Activin-binding protein)FSTP1988325
Glucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2) (Glucosamine-6-phosphate isomerase SB52)GNPDA2 GNP2Q8TDQ725
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)CLCN7P5179825
H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10)NOP10 NOLA3Q9NPE325
HEAT repeat-containing protein 5BHEATR5B KIAA1414Q9P2D325
HLA class I histocompatibility antigen, B-47 alpha chain (Bw-47) (MHC class I antigen B*47)HLA-B HLABP3048525
HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1)HLA-DQB1 HLA-DQBP0192025
Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II) (Keratin-33B) (K33B)KRT33B HHA3-II HKA3B KRTHA3BQ1452525
Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT)KRT20P3590025
LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)LMO7 FBX20 FBXO20 KIAA0858Q8WWI125
Limbic system-associated membrane protein (LSAMP) (IgLON family member 3)LSAMP IGLON3 LAMPQ1344925
Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)MROH1 HEATR7A KIAA1833Q8NDA825
Meprin A subunit alpha (EC 3.4.24.18) (Endopeptidase-2) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha)MEP1AQ1681925
Metalloreductase STEAP2 (EC 1.16.1.-) (Prostate cancer-associated protein 1) (Protein up-regulated in metastatic prostate cancer) (PUMPCn) (Six-transmembrane epithelial antigen of prostate 2) (SixTransMembrane protein of prostate 1)STEAP2 PCANAP1 STAMP1 UNQ6507/PRO23203Q8NFT225
Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B)FAM96B MIP18 CGI-128 HSPC118Q9Y3D025
Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 12)ABHD12 C20orf22Q8N2K025
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)NDUFA10O9529925
Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B)NBEA BCL8B KIAA1544 LYST2Q8NFP925
Nuclear distribution protein nudE homolog 1 (NudE)NDE1 NUDEQ9NXR125
Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Nucleoporin Nup160)NUP160 KIAA0197 NUP120Q1276925
Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)NUP50 NPAP60L PRO1146Q9UKX725
Opioid growth factor receptor (OGFr) (Protein 7-60) (Zeta-type opioid receptor)OGFRQ9NZT225
Plakophilin-4 (p0071)PKP4Q9956925
Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (PH and FYVE domain-containing protein 1) (Phafin-1) (Zinc finger FYVE domain-containing protein 15)PLEKHF1 APPD LAPF ZFYVE15Q96S9925
Proteasome assembly chaperone 4 (PAC-4) (hPAC4)PSMG4 C6orf86 PAC4Q5JS5425
Protein mago nashi homologMAGOH MAGOHAP6132625
Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)PPM1B PP2CBO7568825
Protein RER1RER1O1525825
Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29)RAB29 RAB7L1O1496625
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)SRRM1 SRM160Q8IYB325
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]STK4 KRS2 MST1Q1304325
Small integral membrane protein 1 (Vel blood group antigen)SMIM1B2RUZ425
Small integral membrane protein 24SMIM24 C19orf77 HSPC323O7526425
Sodium-dependent phosphate transporter 1 (Gibbon ape leukemia virus receptor 1) (GLVR-1) (Leukemia virus receptor 1 homolog) (Phosphate transporter 1) (PiT-1) (Solute carrier family 20 member 1)SLC20A1 GLVR1 PIT1Q8WUM925
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)SPTBN4 KIAA1642 SPTBN3Q9H25425
Syntaxin-binding protein 6 (Amisyn)STXBP6 HSPC156Q8NFX725
TBC1 domain family member 2A (Armus) (Prostate antigen recognized and identified by SEREX 1) (PARIS-1)TBC1D2 PARIS1 PP8997 TBC1D2AQ9BYX225
Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III)TGFBR3Q0316725
Transmembrane protein 205TMEM205 UNQ501/PRO1018Q6UW6825
Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100)TRIM47 GOA RNF100Q96LD425
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