EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)LPCAT1 AYTL2 PFAAP3Q8NF3719
Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)MAGT1 IAG2 PSEC0084 UNQ628/PRO1244Q9H0U319
Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein)MFSD10 TETRANQ1472819
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)MECP2P5160819
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1)ALDH6A1 MMSDHQ0225219
MIP18 family protein FAM96AFAM96AQ9H5X119
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)MAVS IPS1 KIAA1271 VISAQ7Z43419
MOB kinase activator 3A (MOB-LAK) (Mob1 homolog 2A) (Mps one binder kinase activator-like 2A)MOB3A MOBKL2AQ96BX819
Myelin proteolipid protein (PLP) (Lipophilin)PLP1 PLPP6020119
Myeloid cell nuclear differentiation antigenMNDAP4121819
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)MYH9Q60FE219
N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2)GALK2 GK2Q0141519
N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma)GNPTG C16orf27 GNPTAG CAB56184 LP2537Q9UJJ919
N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)ASMTLO9567119
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)NDUFS2O7530619
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]NECTIN4 LNIR PRR4 PVRL4Q96NY819
Neuroguidin (Centromere accumulated nuclear protein 1) (CANu1) (EIF4E-binding protein)NGDN C14orf120Q8NEJ919
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)NUP153P4979019
Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]NUP98 ADAR2P5294819
Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap)NOL6Q9H6R419
Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37)NUP37Q8NFH419
O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase)MACROD1 LRP16Q9BQ6919
Oxidation resistance protein 1OXR1 Nbla00307Q8N57319
Oxytocin receptor (OT-R)OXTRP3055919
P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)P2RX7Q9957219
Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIase A-like 4A) (EC 5.2.1.8) (Chromosome one-amplified sequence 2) (COAS-2) (Cyclophilin homolog overexpressed in liver cancer)PPIAL4A COAS2 PPIAL4BQ9Y53619
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PIP5KIbeta) (Protein STM-7) (Type I phosphatidylinositol 4-phosphate 5-kinase beta)PIP5K1B STM7O1498619
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)PIP5K1C KIAA0589O6033119
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (hLHPP) (EC 3.1.3.-) (EC 3.6.1.1)LHPPQ9H00819
Prenylated Rab acceptor protein 1 (PRA1 family protein 1)RABAC1 PRA1 PRAF1Q9UI1419
Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60)DDX60Q8IY2119
Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2)MCF2L2 DRG KIAA0861Q86YR719
Protein crumbs homolog 3CRB3 UNQ588/PRO1158Q9BUF719
Protein FAM168A (Tongue cancer chemotherapy resistance-associated protein 1)FAM168A KIAA0280 TCRP1Q9256719
Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b)PATL1 OK/KNS-cl.5Q86TB919
Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1)PPP1R21 CCDC128 KLRAQ1Q6ZMI019
Protein SMG9 (Protein SMG-9)SMG9 C19orf61Q9H0W819
Protein YIF1B (YIP1-interacting factor homolog B)YIF1B PP4519 UNQ3073/PRO9905Q5BJH719
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)RAB11FIP5 GAF1 KIAA0857 RIP11Q9BXF619
Ran-binding protein 6 (RanBP6)RANBP6O6051819
Ras-related protein Rab-20RAB20Q9NX5719
Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE)RHPN2Q8IUC419
Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)SACS KIAA0730Q9NZJ419
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)SAFB HAP HET SAFB1Q1542419
Secreted and transmembrane protein 1 (Protein K-12)SECTM1 K12Q8WVN619
Secretogranin-1 (Chromogranin-B) (CgB) (Secretogranin I) (SgI) [Cleaved into: PE-11; GAWK peptide; CCB peptide]CHGB SCG1P0506019
Serine dehydratase-like (L-serine deaminase) (L-serine dehydratase/L-threonine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2) (EC 4.3.1.17)SDSLQ96GA719
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)PAK1Q1315319
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)PLK1 PLKP5335019
SH3 domain-binding glutamic acid-rich-like protein 2 (Fovea-associated SH3 domain-binding protein)SH3BGRL2 FASH3Q9UJC519
Small integral membrane protein 22SMIM22K7EJ4619
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14)SLC6A14Q9UN7619
Sodium/glucose cotransporter 5 (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10)SLC5A10 SGLT5A0PJK119
Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)SLC13A2 NADC1 SDCT1Q1318319
Stromal interaction molecule 1STIM1 GOKQ1358619
Sulfotransferase 1A4 (ST1A4) (EC 2.8.2.1) (Aryl sulfotransferase 1A3/1A4) (Sulfotransferase 1A3/1A4)SULT1A4P0DMN019
Syntenin-1 (cDNA FLJ55055, moderately similar to Syntenin-1)SDCBPB4DHN519
Telomere length regulation protein TEL2 homolog (Protein clk-2 homolog) (hCLK2)TELO2 KIAA0683Q9Y4R819
Torsin-1A (Dystonia 1 protein) (Torsin ATPase-1A) (EC 3.6.4.-) (Torsin family 1 member A)TOR1A DQ2 DYT1 TA TORAO1465619
Trafficking protein particle complex subunit 2-like proteinTRAPPC2L HSPC126Q9UL3319
TSC22 domain family protein 1 (Cerebral protein 2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)TSC22D1 KIAA1994 TGFB1I4 TSC22 hucep-2Q1571419
Tumor necrosis factor receptor superfamily member 11B (Osteoclastogenesis inhibitory factor) (Osteoprotegerin)TNFRSF11B OCIF OPGO0030019
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)PTPN13 PNP1 PTP1E PTPL1Q1292319
U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2)IMP3 C15orf12 MRPS4Q9NV3119
Uncharacterized protein C1orf21 (Cell proliferation-inducing gene 13 protein)C1orf21 PIG13Q9H24619
Uroplakin-1b (UP1b) (Tetraspanin-20) (Tspan-20) (Uroplakin Ib) (UPIb)UPK1B TSPAN20O7584119
Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein)HVCN1 VSOP UNQ578/PRO1140Q96D9619
WD repeat-containing protein 44 (Rabphilin-11)WDR44Q5JSH319
Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)XPR1 SYG1 XRQ9UBH619
Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein)ZNF638 NP220 ZFMLQ1496619
28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt) (Mitochondrial small ribosomal subunit protein mS23)MRPS23 CGI-138 HSPC329Q9Y3D918
39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10) (39S ribosomal protein L8, mitochondrial) (L8mt) (MRP-L8) (Mitochondrial large ribosomal subunit protein uL10m)MRPL10 MRPL8 RPML8Q7Z7H818
40S ribosomal protein S17 (Small ribosomal subunit protein eS17)RPS17 RPS17LP0CW2218
ADP-ribosylation factor-like protein 6 (Bardet-Biedl syndrome 3 protein)ARL6 BBS3Q9H0F718
Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)FUT8Q9BYC518
Annexin (Fragment)ANXA1Q5T3N118
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)ATXN2 ATX2 SCA2 TNRC13Q9970018
Atlastin-1 (EC 3.6.5.-) (Brain-specific GTP-binding protein) (GTP-binding protein 3) (GBP-3) (hGBP3) (Guanine nucleotide-binding protein 3) (Spastic paraplegia 3 protein A)ATL1 GBP3 SPG3AQ8WXF718
Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4)ENPP4 KIAA0879 NPP4Q9Y6X518
Brain protein I3 (pRGR2)BRI3O9541518
Cadherin-related family member 2 (Protocadherin LKC) (PC-LKC) (Protocadherin-24)CDHR2 PCDH24 PCLKCQ9BYE918
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)CANXB4DGP818
Calsyntenin-3 (Alcadein-beta) (Alc-beta)CLSTN3 CS3 KIAA0726Q9BQT918
Capping protein, Arp2/3 and myosin-I linker protein 2 (Capping protein regulator and myosin 1 linker 2) (F-actin-uncapping protein RLTPR) (Leucine-rich repeat-containing protein 16C) (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein)CARMIL2 LRRC16C RLTPRQ6F5E818
CCR4-NOT transcription complex subunit 11CNOT11 C2orf29 C40Q9UKZ118
Cell cycle control protein 50B (P4-ATPase flippase complex beta subunit TMEM30B) (Transmembrane protein 30B)TMEM30B CDC50BQ3MIR418
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)CEP170 FAM68A KAB KIAA0470Q5SW7918
COMM domain-containing protein 1 (Protein Murr1)COMMD1 C2orf5 MURR1Q8N66818
Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4)COG4Q9H9E318
Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7)COG7 UNQ3082/PRO10013P8343618
Cornulin (53 kDa putative calcium-binding protein) (53 kDa squamous epithelial-induced stress protein) (58 kDa heat shock protein) (Squamous epithelial heat shock protein 53) (Tumor-related protein)CRNN C1orf10 DRC1 PDRC1 SEP53Q9UBG318
CSC1-like protein 2 (Transmembrane protein 63B)TMEM63B C6orf110Q5T3F818
Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Cytochrome c1 non-heme 7 kDa protein) (Ubiquinol-cytochrome c reductase complex 7.2 kDa protein)UQCR10 UCRC HSPC119Q9UDW118
Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]PLA2G4A CPLA2 PLA2G4P4771218
DCN1-like protein 5 (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5)DCUN1D5Q9BTE718
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)DLGAP4 DAP4 KIAA0964 SAPAP4Q9Y2H018
DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)MSH3 DUC1 DUGP2058518
DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58)PRIM2 PRIM2AP4964318
Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1P4598518
Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)DNAH10 KIAA2017Q8IVF418
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