EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein)VCPIP1 KIAA1850 VCIP135Q96JH713
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)XRCC1P1888713
DNA replication complex GINS protein PSF3 (GINS complex subunit 3)GINS3 PSF3Q9BRX513
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)POLR1DP0DPB613
Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)DNAH8Q96JB113
E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.-) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)ARIH2 ARI2 TRIAD1 HT005O9537613
EH domain-containing protein 1 (Fragment)EHD1C9JC0313
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)EPHA6 EHK2 HEK12Q9UF3313
ER membrane protein complex subunit 3 (Transmembrane protein 111)EMC3 TMEM111Q9P0I213
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (G1 to S phase transition protein 2 homolog)GSPT2 ERF3BQ8IYD113
Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin)EIF2D HCA56 LGTNP4121413
Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3 gamma) (eIF3 p40 subunit)EIF3S3 EIF3H hCG_20900B3KS9813
Eukaryotic translation initiation factor 5A (eIF-5A) (Fragment)EIF5AI3L39713
Eukaryotic translation initiation factor 5A-1-like (eIF-5A-1-like) (eIF-5A1-like) (Eukaryotic initiation factor 5A isoform 1-like)EIF5AL1Q6IS1413
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)EXOSC9 PMSCL1Q0626513
F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18)FBXL18 FBL18Q96ME113
FERM domain-containing protein 6 (Willin)FRMD6 C14orf31Q96NE913
Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2)FGF2 FGFBP0903813
Four-jointed box protein 1 (Four-jointed protein homolog)FJX1Q86VR813
Full-length cDNA 5-PRIME end of clone CS0DF013YM24 of Fetal brain of Homo sapiens (Human) variant (Fragment)0Q53GF913
Full-length cDNA clone CS0CAP007YF18 of Thymus of Homo sapiens (human)0Q86U1213
Galectin-3-binding proteinLGALS3BPK7EKQ513
GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)]H6PD GDHO9547913
Glutathione S-transferase A5 (EC 2.5.1.18) (GST class-alpha member 5) (Glutathione S-transferase A5-5)GSTA5Q7RTV213
Glutathione S-transferase Mu 5 (EC 2.5.1.18) (GST class-mu 5) (GSTM5-5)GSTM5P4643913
Glycosyltransferase 8 domain-containing protein 1 (EC 2.4.1.-)GLT8D1 GALA4A AD-017 MSTP137 UNQ572/PRO1134Q68CQ713
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)GCC2 KIAA0336 RANBP2L4Q8IWJ213
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)GRB7Q1445113
GTP-binding nuclear protein Ran (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)RAN ARA24 OK/SW-cl.81A8K3Z813
H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3)CLCN3P5179013
Heat shock cognate 71 kDa protein (Fragment)HSPA8E9PLF413
Heat shock cognate 71 kDa protein (Fragment)HSPA8E9PS6513
Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST-2) (EC 2.8.2.-)HS6ST2 PSEC0092Q96MM713
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)KMT2C HALR KIAA1506 MLL3Q8NEZ413
Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (SET domain-containing protein 3)SETD3 C14orf154Q86TU713
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9)SETD7 KIAA1717 KMT7 SET7 SET9Q8WTS613
HLA class II histocompatibility antigen, DM beta chain (MHC class II antigen DMB) (Really interesting new gene 7 protein)HLA-DMB DMB RING7P2806813
HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1)HLA-DPA1 HLA-DP1A HLASBP2003613
Huntingtin-interacting protein K (Huntingtin yeast partner K)HYPK C15orf63 HSPC136Q9NX5513
Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30)HIC2 HRG22 KIAA1020 ZBTB30Q96JB313
Immunoglobulin heavy variable 1-69 (Ig heavy chain V-I region EU) (Ig heavy chain V-I region SIE) (Ig heavy chain V-I region WOL)IGHV1-69P0174213
Immunoglobulin kappa variable 1-16 (Ig kappa chain V-I region BAN)IGKV1-16P0443013
Immunoglobulin kappa variable 2D-40 (Ig kappa chain V-II region Cum)IGKV2D-40P0161413
Immunoglobulin kappa variable 3-15 (Ig kappa chain V-III region CLL) (Ig kappa chain V-III region POM)IGKV3-15P0420713
Immunoglobulin kappa variable 3-20 (Ig kappa chain V-III region B6) (Ig kappa chain V-III region GOL) (Ig kappa chain V-III region HAH) (Ig kappa chain V-III region HIC) (Ig kappa chain V-III region IARC/BL41) (Ig kappa chain V-III region NG9) (Ig kappa chain V-III region SIE) (Ig kappa chain V-III region Ti) (Ig kappa chain V-III region WOL)IGKV3-20P0162213
Immunoglobulin lambda variable 2-14 (Ig lambda chain V-II region NIG-84) (Ig lambda chain V-II region TOG) (Ig lambda chain V-II region VIL)IGLV2-14P0170413
Immunoglobulin superfamily member 8 (Fragment)IGSF8C9J8Z413
Inactive gamma-glutamyltranspeptidase 2 (GGT 2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2)GGT2P3626813
Inactive serine protease 35PRSS35 C6orf158 UNQ522/PRO1057Q8N3Z013
Inhibin beta E chain (Activin beta-E chain)INHBEP5816613
Integrin alpha-9 (Integrin alpha-RLC)ITGA9Q1379713
Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Estrogen-regulated transcript 45 protein) (Promyelocytic leukemia nuclear body-associated protein ISG20)ISG20 HEM45Q96AZ613
Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1)ALPIP0992313
Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2)IFT57 DERP8 ESRRBL1 HIPPIQ9NWB713
Isoleucine--tRNA ligase, cytoplasmic (Isoleucine-tRNA synthetase, isoform CRA_d)IARS hCG_31137J3KR2413
Kallikrein-1 (EC 3.4.21.35) (Kidney/pancreas/salivary gland kallikrein) (Tissue kallikrein)KLK1P0687013
Kallikrein-2 (EC 3.4.21.35) (Glandular kallikrein-1) (hGK-1) (Tissue kallikrein-2)KLK2P2015113
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)KLK6 PRSS18 PRSS9Q9287613
Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I) (Keratin-33A) (K33A)KRT33A HHA3-I HKA3A KRTHA3AO7600913
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)KANK2 ANKRD25 KIAA1518 MXRA3 SIPQ63ZY313
LeupaxinLPXN LDLPO6071113
Lymphocyte antigen 6D (Ly-6D) (E48 antigen)LY6D E48Q1421013
Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)LPCAT2 AGPAT11 AYTL1Q7L5N713
Lysyl oxidase homolog 3 (EC 1.4.3.-) (EC 1.4.3.13) (Lysyl oxidase-like protein 3)LOXL3 LOXLP5821513
Melanoma antigen recognized by T-cells 1 (MART-1) (Antigen LB39-AA) (Antigen SK29-AA) (Protein Melan-A)MLANA MART1Q1665513
Metallothionein-2 (MT-2) (Metallothionein-2A) (Metallothionein-II) (MT-II)MT2A CES1 MT2P0279513
Microtubule-associated protein 2 (MAP-2)MAP2P1113713
Mitochondrial enolase superfamily member 1 (EC 4.2.1.68) (Antisense RNA to thymidylate synthase) (rTS) (L-fuconate dehydratase)ENOSF1 RTS TYMSASQ7L5Y113
Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)MAPK10 JNK3 JNK3A PRKM10 SAPK1BP5377913
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)MAP3K7 TAK1O4331813
Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6)SLC16A6 MCT6 MCT7O1540313
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)SMAD2 MADH2 MADR2Q1579613
Myocilin (Myocilin 55 kDa subunit) (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)]MYOC GLC1A TIGRQ9997213
Myosin light polypeptide 6 (cDNA FLJ56329, highly similar to Myosin light polypeptide 6)MYL6B7Z6Z413
N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]NAAA ASAHL PLTQ0208313
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (Complex I-MNLL) (CI-MNLL) (NADH-ubiquinone oxidoreductase MNLL subunit) [Cleaved into: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, N-terminally processed]NDUFB1O7543813
Neurocalcin-deltaNCALDP6160113
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)HPCA BDR2P8407413
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)HMGN2 HMG17P0520413
Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)]PPP1R8 ARD1 NIPP1Q1297213
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)NCOA4 ARA70 ELE1 RFGQ1377213
Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1)TIA1P3148313
Pappalysin-2 (EC 3.4.24.-) (Pregnancy-associated plasma protein A2) (PAPP-A2) (Pregnancy-associated plasma protein E1) (PAPP-E)PAPPA2 PLAC3Q9BXP813
Paraneoplastic antigen Ma2 (40 kDa neuronal protein) (Onconeuronal antigen Ma2) (Paraneoplastic neuronal antigen MM2)PNMA2 KIAA0883 MA2Q9UL4213
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)PARD3 PAR3 PAR3AQ8TEW013
PDZ and LIM domain protein 2 (PDZ-LIM protein mystique)PDLIM2 PP6345Q96JY613
Phospholipase A1 member A (EC 3.1.1.-) (Phosphatidylserine-specific phospholipase A1) (PS-PLA1)PLA1A NMD PSPLA1Q53H7613
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)PHKA1 PHKAP4602013
pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)FTSJ3 SB92Q8IY8113
Pregnancy zone proteinPZPF5GXY013
Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor)BUD23 MERM1 WBSCR22 HUSSY-03 PP3381O4370913
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)CIAO1 WDR39O7607113
Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71)PAAF1 WDR71Q9BRP413
Proteasome endopeptidase complex (EC 3.4.25.1) (Fragment)PSMA7H0Y58613
Proteasome subunit alpha type (EC 3.4.25.1)PSMA6G3V3U413
Proteasome subunit alpha type (EC 3.4.25.1)0B4DEV813
Proteasome subunit beta type (EC 3.4.25.1) (Fragment)0Q53FT813
Protein ABHD17C (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17C) (Abhydrolase domain-containing protein 17C)ABHD17C FAM108C1Q6PCB613
Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4)CNIH4 HSPC163Q9P00313
Protein FAM50A (Protein HXC-26) (Protein XAP-5)FAM50A DXS9928E HXC26 XAP5Q1432013
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