EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)FNTBP4935613
Protein FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog)FMC1 C7orf55 HSPC268Q96HJ913
Protein jagunal homolog 1JAGN1Q8N5M913
Protein MAK16 homolog (NNP78) (Protein RBM13)MAK16 RBM13Q9BXY013
Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1)PRUNE2 BMCC1 BNIPXL C9orf65 KIAA0367Q8WUY313
Protein Wnt-5bWNT5BQ9H1J713
Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III)PADI3 PAD3 PDI3Q9ULW813
Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2)PCDH12 UNQ395/PRO731Q9NPG413
PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)GULP1 CED6 GULPQ9UBP913
Ral GTPase-activating protein subunit beta (p170)RALGAPB KIAA1219Q86X1013
Ras-related protein Rab-7a (Fragment)RAB7AC9J59213
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]ERBB4 HER4Q1530313
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)PTPRZ1 HTPZP2 PTPRZ PTPRZ2 PTPZP2347113
REST corepressor 1 (Protein CoREST)RCOR1 KIAA0071 RCORQ9UKL013
Retrotransposon-derived protein PEG10 (Embryonal carcinoma differentiation-regulated protein) (Mammalian retrotransposon-derived protein 2) (Myelin expression factor 3-like protein 1) (MEF3-like protein 1) (Paternally expressed gene 10 protein) (Retrotransposon gag domain-containing protein 3) (Retrotransposon-derived gag-like polyprotein) (Ty3/Gypsy-like protein)PEG10 EDR KIAA1051 MAR2 MART2 MEF3L1 RGAG3Q86TG713
Rho GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (Rho-type GTPase-activating protein 4) (p115)ARHGAP4 KIAA0131 RGC1 RHOGAP4P9817113
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)RHOBTB3 KIAA0878O9495513
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)RRP1B KIAA0179Q1468413
Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog)BMS1 BMS1L KIAA0187Q1469213
RILP-like protein 1 (Rab-interacting lysosomal-like protein 1)RILPL1 RLP1Q5EBL413
RNA polymerase II-associated protein 3RPAP3Q9H6T313
Secretogranin-3 (Secretogranin III) (SgIII)SCG3 UNQ2502/PRO5990Q8WXD213
Semaphorin-4BSEMA4B KIAA1745 SEMAC UNQ749/PRO1480Q9NPR213
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431Q9UL5413
Serine/threonine-protein phosphatase 4 regulatory subunit 1PPP4R1 MEG1 PP4R1Q8TF0513
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)ANKRD44Q8N8A213
Serologically defined colon cancer antigen 3 (Antigen NY-CO-3)SDCCAG3Q96C9213
Signaling threshold-regulating transmembrane adapter 1 (SHP2-interacting transmembrane adapter protein) (Suppression-inducing transmembrane adapter 1) (gp30/40)SIT1 SITQ9Y3P813
Slit homolog 3 protein (Slit-3) (Multiple epidermal growth factor-like domains protein 5) (Multiple EGF-like domains protein 5)SLIT3 KIAA0814 MEGF5 SLIL2 UNQ691/PRO1336O7509413
Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3)SLC6A15 B0AT2 NTT73 SBAT1Q9H2J713
Solute carrier family 22 member 12 (Organic anion transporter 4-like protein) (Renal-specific transporter) (RST) (Urate anion exchanger 1)SLC22A12 OATL4 URAT1 UNQ6453/PRO34004Q96S3713
Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1)SLC22A6 OAT1 PAHTQ4U2R813
Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)SLCO4A1 OATP1 OATP4A1 OATPE SLC21A12Q96BD013
Spermatogenesis-associated protein 5-like protein 1SPATA5L1Q9BVQ713
Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2)SULT1C2 SULT1C1O0033813
Synaptotagmin-like protein 2 (Breast cancer-associated antigen SGA-72M) (Exophilin-4)SYTL2 KIAA1597 SGA72M SLP2 SLP2AQ9HCH513
Syndecan-3 (SYND3)SDC3 KIAA0468O7505613
Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2)STX1B STX1B1 STX1B2P6126613
Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]TENM2 KIAA1127 ODZ2 TNM2Q9NT6813
Tetraspanin-13 (Tspan-13) (Tetraspan NET-6) (Transmembrane 4 superfamily member 13)TSPAN13 NET6 TM4SF13 UNQ260/PRO296O9585713
Thyroid adenoma-associated protein (Gene inducing thyroid adenomas protein)THADA GITA KIAA1767Q6YHU613
Trafficking protein particle complex subunit 11TRAPPC11 C4orf41Q7Z39213
Transaldolase (EC 2.2.1.2)TALDO1F2Z39313
Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma)GTF2A2 TF2A2P5265713
Transgelin-3 (Neuronal protein 22) (NP22) (Neuronal protein NP25)TAGLN3 NP25Q9UI1513
Translationally-controlled tumor proteinTPT1Q5W0H413
Transmembrane protein 14CTMEM14C C6orf53 HSPC194Q9P0S913
Transmembrane protein 179BTMEM179BQ7Z7N913
Transmembrane protein 258TMEM258 C11orf10 HSPC005P6116513
Transmembrane protein 47 (Brain cell membrane protein 1) (Transmembrane 4 superfamily member 10)TMEM47 BCMP1 TM4SF10Q9BQJ413
tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)TRMT5 KIAA1393 TRM5Q32P4113
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (WD repeat-containing protein 4)WDR4P5708113
TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1)TSC22D4 THG1 TILZ2Q9Y3Q813
Tuberin (Tuberous sclerosis 2 protein)TSC2 TSC4P4981513
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)TNFSF10 APO2L TRAILP5059113
Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)TNFRSF12A FN14Q9NP8413
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271)NGFR TNFRSF16P0813813
Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)YARS2 CGI-04Q9Y2Z413
Tyrosine-protein kinase (EC 2.7.10.2) (Fragment)LYNQ6NUK713
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)USP13 ISOT3Q9299513
UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)UBXN4 KIAA0242 UBXD2 UBXDC1Q9257513
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)SORBS3 SCAM1O6050413
Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1)VKORC1 VKOR MSTP134 MSTP576 UNQ308/PRO351Q9BQB613
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4)VKORC1L1Q8N0U813
VitronectinVTND9ZGG213
WD repeat-containing protein 37WDR37 KIAA0982Q9Y2I813
Zinc finger CCHC domain-containing protein 3ZCCHC3 C20orf99Q9NUD513
Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2)SLC30A7 ZNT7 ZNTL2Q8NEW013
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3)PLCH1 KIAA1069 PLCL3Q4KWH812
28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt) (Mitochondrial small ribosomal subunit protein bS16m)MRPS16 RPMS16 CGI-132Q9Y3D312
28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt) (Mitochondrial small ribosomal subunit protein mS33)MRPS33 CGI-139 PTD003Q9Y29112
28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt) (Mitochondrial small ribosomal subunit protein uS9m)MRPS9 RPMS9P8293312
3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)HAAOP4695212
39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45) (Mitochondrial large ribosomal subunit protein mL45)MRPL45Q9BRJ212
39S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt) (Mitochondrial large ribosomal subunit protein mL65) (Mitochondrial large ribosomal subunit protein mS30) (Programmed cell death protein 9)MRPS30 PDCD9 BM-047Q9NP9212
40S ribosomal protein S6RPS6Q96DV612
4F2 cell-surface antigen heavy chainSLC3A2F5GZS612
5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1)TYRP1 CAS2 TYRP TYRRPP1764312
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)AKAP13 BRX HT31 LBCQ1280212
Actin, cytoplasmic 2 (Fragment)ACTG1I3L1U912
Actin, gamma-enteric smooth muscle (Fragment)ACTG2C9JFL512
Acylphosphatase-2 (EC 3.6.1.7) (Acylphosphatase, muscle type isozyme) (Acylphosphate phosphohydrolase 2)ACYP2 ACYPP1462112
Adenylyl cyclase-associated proteinCAP1 hCG_2033246D3DPU212
Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312)ADGRE2 EMR2Q9UHX312
Aflatoxin B1 aldehyde reductase member 2 (Fragment)AKR7A2H3BLU712
Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) (Chondroitin sulfate proteoglycan 1) [Cleaved into: Aggrecan core protein 2]ACAN AGC1 CSPG1 MSK16P1611212
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)AARS2 AARSL KIAA1270Q5JTZ912
Alcohol dehydrogenase 1C (EC 1.1.1.1) (Alcohol dehydrogenase subunit gamma)ADH1C ADH3P0032612
Alpha-2-HS-glycoproteinAHSGC9JV7712
Alpha-2-macroglobulin (Fragment)A2MQ9BQ2212
Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)MAN2A2 MANA2XP4964112
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)ANAPC4 APC4Q9UJX512
Angiogenin (EC 3.1.27.-) (Ribonuclease 5) (RNase 5)ANG RNASE5P0395012
Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK)ANKHD1 KIAA1085 MASK VBARP PP2500Q8IWZ312
Annexin A8-like protein 1ANXA8L1 ANXA8L2Q5VT7912
Arpin (Arp2/3 inhibition protein)ARPIN C15orf38Q7Z6K512
Battenin (Batten disease protein) (Protein CLN3)CLN3 BTSQ1328612
Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)BCL2L13 MIL1 CD003Q9BXK512
Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b)SGCBQ1658512
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)JMJD6 KIAA0585 PTDSRQ6NYC112
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