EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]PNKPQ96T6012
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)BMP4 BMP2B DVR4P1264412
Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa)BMP7 OP1P1807512
Breast carcinoma-amplified sequence 1 (Amplified and overexpressed in breast cancer) (Novel amplified in breast cancer 1)BCAS1 AIBC1 NABC1O7536312
Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin)CDH15 CDH14 CDH3P5529112
Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)MCU C10orf42 CCDC109AQ8NE8612
cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)PRKACGP2261212
Cartilage intermediate layer protein 1 (CILP-1) (Cartilage intermediate-layer protein) [Cleaved into: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2]CILP UNQ602/PRO1188O7533912
Caskin-2 (CASK-interacting protein 2)CASKIN2 KIAA1139Q8WXE012
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)CD226 DNAM1Q1576212
Cdc42 effector protein 4 (Binder of Rho GTPases 4)CDC42EP4 BORG4 CEP4Q9H3Q112
cDNA FLJ32377 fis, clone SKMUS1000014, highly similar to Polyubiquitin 90Q96MH412
cDNA FLJ36887 fis, clone BNGH42005504, highly similar to 26S PROTEASOME REGULATORY SUBUNIT S30Q8N9M212
cDNA FLJ537580B7Z95312
cDNA FLJ54573, highly similar to Importin beta-30B4E0R612
cDNA FLJ55347, highly similar to EH-domain-containing protein 10B4DTR412
cDNA FLJ56120, highly similar to Aminopeptidase N (EC 3.4.11.2)0B4DP0112
Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)CEP350 CAP350 KIAA0480 GM133Q5VT0612
cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)PDE5A PDE5O7607412
Chromatin accessibility complex protein 1 (CHRAC-1) (Chromatin accessibility complex 15 kDa protein) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15)CHRAC1 CHRAC15Q9NRG012
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)CHD3Q1287312
Ciliary neurotrophic factor receptor subunit alpha (CNTF receptor subunit alpha) (CNTFR-alpha)CNTFRP2699212
Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin]COL8A1 C3orf7P2765812
Collagen alpha-1(XII) chainCOL12A1D6RGG312
Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190)CNTNAP1 CASPR NRXN4P7835712
Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)CDK18 PCTAIRE3 PCTK3Q0700212
Cysteine-rich tail protein 1CYSRT1 C9orf169A8MQ0312
Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase)CDA CDDP3232012
Cytochrome c oxidase protein 20 homologCOX20 FAM36AQ5RI1512
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)SPECC1 CYTSB NSP5Q5M77512
DENN domain-containing protein 4CDENND4C C9orf55 C9orf55BQ5VZ8912
Deoxyhypusine hydroxylase (hDOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase) (HEAT-like repeat-containing protein 1)DOHH HLRC1Q9BU8912
Digestive organ expansion factor homologDIEXF C1orf107 DEFQ68CQ412
DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49)PRIM1P4964212
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]GINS4 SLD5Q9BRT912
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)POLR1BQ9H9Y612
DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62)POLR3CQ9BUI412
Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2))DOK2O6049612
Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)DNAH1 DHC7 DNAHC1 KIAA1410Q9P2D712
Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b)DNAH3 DNAHC3BQ8TD5712
Dynein heavy chain 9, axonemal (Axonemal beta dynein heavy chain 9) (Ciliary dynein heavy chain 9)DNAH9 DNAH17L DNAL1 KIAA0357Q9NYC912
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)HERC5 CEB1 CEBP1Q9UII412
E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase pellino homolog 2)PELI2Q9HAT812
Ecto-ADP-ribosyltransferase 3 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 3) (ARTC3) (Mono(ADP-ribosyl)transferase 3) (NAD(P)(+)--arginine ADP-ribosyltransferase 3)ART3 TMARTQ1350812
EF-hand calcium-binding domain-containing protein 5EFCAB5A4FU6912
Engulfment and cell motility protein 3ELMO3Q96BJ812
Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)EPHB6O1519712
Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8)EFNB3 EPLG8 LERK8Q1576812
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)EGFL7 MEGF7 UNQ187/PRO1449Q9UHF112
Epididymis luminal protein 189 (Putative uncharacterized protein DKFZp686J1372) (Tropomyosin alpha-3 chain)DKFZp686J1372 HEL-189 TPM3Q5HYB612
Epididymis luminal protein 4 (Epididymis secretory protein Li 3) (Epididymis secretory protein Li 93) (Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta polypeptide) (Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, isoform CRA_a)YWHAZ HEL-S-3 HEL-S-93 HEL4 hCG_2009146D0PNI112
Epididymis-specific alpha-mannosidase (EC 3.2.1.24) (Mannosidase alpha class 2B member 2)MAN2B2 KIAA0935Q9Y2E512
Eukaryotic initiation factor 4A-IIEIF4A2E7EQG212
Extracellular sulfatase Sulf-1 (hSulf-1) (EC 3.1.6.-)SULF1 KIAA1077Q8IWU612
Factor VIII intron 22 protein (CpG island protein)F8A1 F8A; F8A2 F8A; F8A3 F8AP2361012
Fibrinogen-like protein 1 (HP-041) (Hepassocin) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1)FGL1 HFREP1Q0883012
FLNA protein (Fragment)FLNAQ6NXF212
Forkhead box protein K1 (Myocyte nuclear factor) (MNF)FOXK1 MNFP8503712
Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)FNBP1 FBP17 KIAA0554Q96RU312
Fructose-bisphosphate aldolase A (Fragment)ALDOAH3BR0412
G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)GRK5 GPRK5P3494712
Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase)GALTP0790212
Galectin-3-binding proteinLGALS3BPK7ERZ612
Galectin-9B (Gal-9B) (Galectin-9-like protein A)LGALS9BQ3B8N212
Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2)SLC37A2Q8TED412
Glyceraldehyde-3-phosphate dehydrogenaseGAPDHE7EUT512
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)GOSR1 GS28O9524912
Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)GOSR2 GS27O1465312
Growth arrest-specific protein 7 (GAS-7)GAS7 KIAA0394O6086112
HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C)HAUS1 CCDC5 HEICQ96CS212
Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20)HSPB6O1455812
Heterogeneous nuclear ribonucleoprotein HHNRNPH1E9PCY712
Histone deacetylase 6 (HD6) (EC 3.5.1.98)HDAC6 KIAA0901 JM21Q9UBN712
Histone H2B type F-S (Histone H2B.s) (H2B/s)H2BFSP5705312
HLA class I histocompatibility antigen, B-56 alpha chain (Bw-22) (Bw-56) (MHC class I antigen B*56)HLA-B HLABP3049512
HLA class I histocompatibility antigen, B-82 alpha chain (MHC class I antigen B*82)HLA-B HLABQ2971812
HLA class II histocompatibility antigen, DRB1-16 beta chain (MHC class II antigen DRB1*16) (DR-16) (DR16)HLA-DRB1Q2997412
HSPA9 protein (Fragment)HSPA9Q8N1C812
Immunoglobulin kappa variable 1D-33 (Ig kappa chain V-I region AG) (Ig kappa chain V-I region Bi) (Ig kappa chain V-I region Lay) (Ig kappa chain V-I region Ni) (Ig kappa chain V-I region Rei) (Ig kappa chain V-I region Roy) (Ig kappa chain V-I region Scw) (Ig kappa chain V-I region WAT)IGKV1D-33P0160912
Immunoglobulin kappa variable 3-20 (Ig kappa chain V-III region B6) (Ig kappa chain V-III region GOL) (Ig kappa chain V-III region HAH) (Ig kappa chain V-III region HIC) (Ig kappa chain V-III region IARC/BL41) (Ig kappa chain V-III region NG9) (Ig kappa chain V-III region SIE) (Ig kappa chain V-III region Ti) (Ig kappa chain V-III region WOL)IGKV3-20P0420612
Immunoglobulin superfamily member 2 (IgSF2) (Cell surface glycoprotein V7) (Glu-Trp-Ile EWI motif-containing protein 101) (EWI-101) (CD antigen CD101)CD101 EWI101 IGSF2 V7Q9303312
Inhibin beta B chain (Activin beta-B chain)INHBBP0952912
Integral membrane protein GPR155 (G-protein coupled receptor PGR22)GPR155 PGR22Q7Z3F112
Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2)IREB2P4820012
Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6) (Keratin-36) (K36)KRT36 HHA6 HKA6 KRTHA6O7601312
Kinesin-like protein KIFC3KIFC3Q9BVG812
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)LARP4B KIAA0217 LARP5Q9261512
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.13.70) (CYPLI) (Cytochrome P450 51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase)CYP51A1 CYP51Q1685012
Leucine zipper transcription factor-like protein 1LZTFL1Q9NQ4812
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)LRRK2 PARK8Q5S00712
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)LRP1B LRPDITQ9NZR212
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)MAN1A2 MAN1BO6047612
Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18)MMP19 MMP18 RASIQ9954212
Matrix-remodeling-associated protein 7 (Transmembrane anchor protein 1)MXRA7 TMAP1P8415712
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)MED20 TRFPQ9H94412
Metastasis-associated in colon cancer protein 1 (SH3 domain-containing protein 7a5)MACC1Q6ZN2812
Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2)MBD2Q9UBB512
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)MCCC1 MCCAQ96RQ312
Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP)APIP CGI-29Q96GX912
Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2)MFAP5 MAGP2Q1336112
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