EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFRP1136211
Fibronectin (Fragment)FN1H0Y4K811
Follistatin-related protein 4 (Follistatin-like protein 4)FSTL4 KIAA1061Q6MZW211
Fructose-bisphosphate aldolase (EC 4.1.2.13)ALDOA hCG_1811258J3KPS311
Fructose-bisphosphate aldolase A (Fragment)ALDOAH3BPS811
FYN-binding protein (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)FYB SLAP130O1511711
G patch domain-containing protein 8GPATCH8 GPATC8 KIAA0553Q9UKJ311
Galectin-3-binding protein (Fragment)LGALS3BPK7ES7511
Gamma-parvinPARVGQ9HBI011
Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)TUBGCP4 76P GCP4Q9UGJ111
Gasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT); Gasdermin-D, C-terminal (GSDMD-CT)]GSDMD DFNA5L GSDMDC1 FKSG10P5776411
General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)GTF3C1Q1278911
Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3)GLUD2 GLUDP1P4944811
Glutathione S-transferase A3 (EC 2.5.1.18) (GST class-alpha member 3) (Glutathione S-transferase A3-3)GSTA3Q1677211
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)GNB3P1652011
Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2)GBP2P3245611
HAUS augmin-like complex subunit 6HAUS6 DGT6 FAM29A KIAA1574Q7Z4H711
HCG15971, isoform CRA_a (PS1TP5-binding protein 1)PS1TP5BP1 hCG_15971Q1KLZ011
HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1)HEATR6 ABC1Q6AI0811
Heat shock cognate 71 kDa protein (Fragment)HSPA8E9PM1311
Hemoglobin subunit deltaHBDE9PFT611
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)HNRNPCL2 HNRNPCP5B2RXH811
Histone H3 (Fragment)H3F3BK7EK0711
HLA class I histocompatibility antigen, A-31 alpha chain (MHC class I antigen A*31)HLA-A HLAAP1618911
HLA class I histocompatibility antigen, B-67 alpha chain (MHC class I antigen B*67)HLA-B HLABQ2983611
HLA class I histocompatibility antigen, Cw-5 alpha chain (MHC class I antigen Cw*5)HLA-C HLACQ9TNN711
HLA class II histocompatibility antigen, DRB1-9 beta chain (MHC class II antigen DRB1*9) (DR-9) (DR9)HLA-DRB1Q9TQE011
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1)CUX1 CUTL1P3988011
HSPA8 protein (Fragment)HSPA8Q96IS611
IGK@ proteinIGK@Q6P5S811
Immunoglobulin lambda constant 3 (Ig lambda chain C region DOT) (Ig lambda chain C region NEWM) (Ig lambda-3 chain C regions)IGLC3P0CG0611
Immunoglobulin lambda variable 2-23 (Ig lambda chain V-II region NEI)IGLV2-23P0170511
Immunoglobulin lambda variable 3-1 (Ig lambda chain V-IV region Bau) (Ig lambda chain V-IV region MOL) (Ig lambda chain V-IV region X)IGLV3-1P0171511
Importin subunit beta-1 (Fragment)KPNB1J3QR4811
Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid 5 homolog 1) (Rhomboid family member 1) (p100hRho)RHBDF1 C16orf8 DIST1 IRHOM1Q96CC611
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.21) (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2)PPIP5K2 HISPPD1 KIAA0433 VIP2O4331411
Inositol polyphosphate 1-phosphatase (IPP) (IPPase) (EC 3.1.3.57)INPP1P4944111
Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A)INTS3 C1orf193 C1orf60Q68E0111
Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)IRF2BP2Q7Z5L911
Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)IFRD1O0045811
Interleukin-1 receptor antagonist protein (IL-1RN) (IL-1ra) (IRAP) (ICIL-1RA) (IL1 inhibitor) (Anakinra)IL1RN IL1F3 IL1RAP1851011
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)ITSN2 KIAA1256 SH3D1B SWAPQ9NZM311
Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)IFT140 KIAA0590 WDTC2Q96RY711
Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1)KLK10 NES1 PRSSL1O4324011
Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein)SLC4A1AP HLC3Q9BWU011
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)KEAP1 INRF2 KIAA0132 KLHL19Q1414511
Keratin, type I cytoskeletal 19 (Fragment)KRT19C9JM5011
Keratin, type II cytoskeletal 8 (Fragment)KRT8H0YIB211
Kinesin-like protein KIF1B (Klp)KIF1B KIAA0591 KIAA1448O6033311
L-lactate dehydrogenase (EC 1.1.1.27) (Fragment)LDHBA8MW5011
La-related protein 4 (La ribonucleoprotein domain family member 4)LARP4 PP13296Q71RC211
LayilinLAYN UNQ208/PRO234Q6UX1511
Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1)LCMT1 LCMT CGI-68Q9UIC811
LIM and calponin homology domains-containing protein 1LIMCH1 KIAA1102Q9UPQ011
Linker for activation of T-cells family member 1 (36 kDa phospho-tyrosine adapter protein) (pp36) (p36-38)LATO4356111
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)PPFIA3 KIAA0654O7514511
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)LCP2Q1309411
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (HMIC) (Mannosidase alpha class 1C member 1) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC)MAN1C1 MAN1A3 MAN1CQ9NR3411
Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein)SPG21 ACP33 BM-019 GL010Q9NZD811
Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)KIT SCFRP1072111
Melanoregulin (Dilute suppressor protein homolog)MREG DSU HDCGA21PQ8N56511
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)MAGI1 AIP3 BAIAP1 BAP1 TNRC19Q96QZ711
Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]MAP1A MAP1LP7855911
Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16)PAM16 MAGMAS TIM16 TIMM16 CGI-136Q9Y3D711
Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (MOCO1-B) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) (Molybdopterin-synthase large subunit) (MPT synthase large subunit)MOCS2 MCBPE MOCO1O9600711
Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10)MEGF10 KIAA1780Q96KG711
Myotubularin-related protein 1 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)MTMR1Q1361311
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (EC 2.4.1.149) (Beta-1,3-N-acetylglucosaminyltransferase 1) (BGnT-1) (Beta-1,3-Gn-T1) (Beta3Gn-T1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (Beta3GalT7) (b3Gal-T7) (Beta-3-Gx-T7) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) (BGnT-2) (Beta-1,3-Gn-T2) (Beta-1,3-N-acetylglucosaminyltransferase 2) (Beta3Gn-T2) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7)B3GNT2 B3GALT7 B3GNT1Q9NY9711
NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)SIRT5 SIR2L5Q9NXA811
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)NDUFB8O9516911
NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b)NDUFC2 HLC1O9529811
Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2)SLC11A2 DCT1 DMT1 NRAMP2 OK/SW-cl.20P4928111
Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)DCC IGDCC1P4314611
Netrin-1 (Epididymis tissue protein Li 131P)NTN1 NTN1LO9563111
Neuromedin-U [Cleaved into: Neuromedin-U-25 (NmU-25)]NMUP4864511
Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6)PNPLA6 NTEQ8IY1711
Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) (eNOS-interacting protein)NOSIP CGI-25Q9Y31411
Nucleolar complex protein 3 homolog (NOC3 protein homolog) (Factor for adipocyte differentiation 24) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein)NOC3L AD24 C10orf117 FAD24Q8WTT211
Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein)OIT3 LZP UNQ826/PRO1753Q8WWZ811
Osteomodulin (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin) (Osteoadherin) (OSAD)OMD SLRR2C UNQ190/PRO216Q9998311
Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)OSBPL11 ORP11 OSBP12Q9BXB411
Phosphatidylethanolamine-binding protein 4 (PEBP-4) (hPEBP4) (Protein cousin-of-RKIP 1)PEBP4 CORK1 UNQ1933/PRO4408Q96S9611
Phosphoribosyltransferase domain-containing protein 1PRTFDC1 HHGPQ9NRG111
Plakoglobin (Fragment)0Q7KZ8611
Plasminogen receptor (KT) (Plg-R(KT))PLGRKT C9orf46 AD025 MDS030Q9HBL711
Pleckstrin homology-like domain family A member 1 (Apoptosis-associated nuclear protein) (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (Proline- and histidine-rich protein) (T-cell death-associated gene 51 protein)PHLDA1 PHRIP TDAG51Q8WV2411
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)PHLDB1 KIAA0638 LL5A DLNB07Q86UU111
Pleckstrin-2PLEK2Q9NYT011
Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)PARP12 ZC3HDC1Q9H0J911
Polyadenylate-binding protein (PABP)PABPC4 hCG_2031827B1ANR011
Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6)GALNT6Q8NCL411
Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb)CWC22 KIAA1604 NCMQ9HCG811
Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1)NPEPL1 KIAA1974Q8NDH311
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)DDX56 DDX21 NOH61Q9NY9311
Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4)HECTD4 C12orf51 KIAA0614Q9Y4D811
Probable G-protein coupled receptor 135GPR135Q8IZ0811
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)SMARCA2 BAF190B BRM SNF2A SNF2L2P5153111
Programmed cell death 6-interacting proteinPDCD6IPF8WDK911
Programmed cell death 6-interacting proteinPDCD6IPF8WEQ711
Prolyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like)PREPL KIAA0436Q4J6C611
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