EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Proteasome subunit alpha type (EC 3.4.25.1)PSMA6G3V5Z711
Proteasome subunit alpha-type 8PSMA8F5GY3411
Protein FAM45AFAM45AQ8TCE611
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)PRKCE PKCEQ0215611
Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8)ZMYND8 KIAA1125 PRKCBP1 RACK7Q9ULU411
Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2)NELL2 NRP2Q9943511
Protein misato homolog 1MSTO1 LST005 SLTP005Q9BUK611
Protein NDNF (Neuron-derived neurotrophic factor)NDNF C4orf31 UNQ2748/PRO6487Q8TB7311
Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11)PDCD11 KIAA0185Q1469011
Protein S100 (S100 calcium-binding protein) (Fragment)S100A6R4GN9811
Protein transport protein Sec23ASEC23AF5H36511
Proton-coupled folate transporter (G21) (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1)SLC46A1 HCP1 PCFTQ96NT511
Putative oxidoreductase GLYR1 (EC 1.-.-.-) (3-hydroxyisobutyrate dehydrogenase-like protein) (Cytokine-like nuclear factor N-PAC) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa)GLYR1 HIBDL NP60Q49A2611
Putative small nuclear ribonucleoprotein G-like protein 15SNRPGP15A8MWD911
Putative uncharacterized protein (Fragment)0Q9BU0811
Pyruvate kinase (EC 2.7.1.40)PKMH3BQ3411
Pyruvate kinase PKM (Fragment)PKMH3BN3411
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)CHM REP1 TCDP2438611
Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)RAPGEF6 PDZGEF2Q8TEU711
Ras-related protein R-Ras2 (Ras-like protein TC21) (Teratocarcinoma oncogene)RRAS2 TC21B7Z5Z211
Ras-related protein Rab-30RAB30Q1577111
Ras-related protein Rab-35 (Fragment)RAB35F5H15711
Ras-related protein Rab-7aRAB7AC9J4V011
Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)RPRD1A P15RSQ96P1611
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)RPTOR KIAA1303 RAPTORQ8N12211
REST corepressor 3RCOR3 KIAA1343Q9P2K311
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17)PDE6D PDEDO4392411
Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1)ARHGAP6 RHOGAP6O4318211
Rho guanine nucleotide exchange factor 40 (Protein SOLO)ARHGEF40 SOLOQ8TER511
RNA-binding protein 26 (CTCL tumor antigen se70-2) (RNA-binding motif protein 26)RBM26 C13orf10 PRO1777Q5T8P611
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)RYR2Q9273611
Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific)EEFSEC SELBP5777211
Septin-7SEPT7E7EPK111
Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)PRKD2 PKD2 HSPC187Q9BZL611
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)DCLK1 DCAMKL1 DCDC3A KIAA0369O1507511
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)PPP2R2D KIAA1541Q66LE611
Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1)PPP4R3A KIAA2010 PP4R3A SMEK1 MSTP033Q6IN8511
Serpin A12 (OL-64) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (Visceral adipose-specific serpin)SERPINA12Q8IW7511
SH3 domain-binding protein 1 (3BP-1)SH3BP1Q9Y3L311
Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)SIGLEC9 UNQ668/PRO1302Q9Y33611
Signal transducer and activator of transcription 5ASTAT5A STAT5P4222911
SLAIN motif-containing protein 2SLAIN2 KIAA1458Q9P27011
SLIT and NTRK-like protein 4SLITRK4Q8IW5211
Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3)SLC9A3 NHE3P4876411
Solute carrier organic anion transporter family member 3A1 (OATP3A1) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (Organic anion-transporting polypeptide D) (OATP-D) (PGE1 transporter) (Sodium-independent organic anion transporter D) (Solute carrier family 21 member 11)SLCO3A1 OATP3A1 OATPD SLC21A11Q9UIG811
Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (CRL1) (Disrupter of silencing SAS10) (UTP3 homolog)UTP3 CRLZ1 SAS10Q9NQZ211
SorcinSRIC9J0K611
Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (Retinoic acid-induced protein 70) (SKAP55 homolog) (SKAP-55HOM) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains)SKAP2 PRAP RA70 SAPS SCAP2 SKAP55RO7556311
Stromal membrane-associated protein 1SMAP1Q8IYB511
Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2)SULT2B1 HSST2O0020411
Synaptic vesicle membrane protein VAT-1 homolog-like (EC 1.-.-.-)VAT1L KIAA1576Q9HCJ611
Synaptophysin-like protein 1SYPL1C9JYN011
Syndecan binding protein (Syntenin), isoform CRA_a (Syntenin-1)SDCBP hCG_1787561G5EA0911
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)STXBP5 LLGL3Q5T5C011
Syntenin-1SDCBPE9PBU711
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)SDCBP MDA9 SYCLB2R5Q711
T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)CD1AP0612611
T-complex protein 1 subunit gamma (Fragment)0Q59H7711
TenascinTNCJ3QSU611
Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)]TENM1 ODZ1 TNM1Q9UKZ411
TetranectinCLEC3BE9PHK011
Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog)TTC21B IFT139 KIAA1992 Nbla10696Q7Z4L511
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)TGFBR1 ALK5 SKR4P3689711
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)TAB1 MAP3K7IP1Q1575011
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)THOC3Q96J0111
Thrombospondin type-1 domain-containing protein 7ATHSD7A KIAA0960Q9UPZ611
Thrombospondin-1THBS1 TSP TSP1Q59E9911
Torsin-1A-interacting protein 2, isoform IFRG15 (15 kDa interferon-responsive protein) (IFRG15)TOR1AIP2 IFRG15Q9H49611
Torsin-4A (Torsin family 4 member A)TOR4A C9orf167Q9NXH811
Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II)GTF2B TF2B TFIIBQ0040311
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)TLE3 KIAA1547Q0472611
Transferrin receptor protein 1TFRCF8WBE511
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)TACC1 KIAA1103O7541011
Translation machinery-associated protein 16TMA16 C4orf43Q96EY411
Transmembrane protein 230TMEM230 C20orf30 HSPC274 UNQ2432/PRO4992Q96A5711
TRMT1-like protein (EC 2.1.1.-)TRMT1L C1orf25 TRM1L MSTP070Q7Z2T511
Tubulin alpha chain (Fragment)TUBA1AF8VQQ411
Tubulin alpha-1B chain (Fragment)TUBA1BF8VVB911
Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)TNFRSF21 DR6 UNQ437/PRO868O7550911
Ubiquitin carboxyl-terminal hydrolase 14USP14A6NJA211
Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog)UBFD1 UBPHO1456211
Uncharacterized protein0A0A5E411
UTP--glucose-1-phosphate uridylyltransferaseUGP2E7EUC711
WD repeat-containing protein 13WDR13Q9H1Z411
WD repeat-containing protein 20 (Protein DMR)WDR20Q8TBZ311
YTH domain-containing family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)YTHDF1 C20orf21Q9BYJ911
Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8)ZCCHC8Q6NZY411
Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)ZRANB2 ZIS ZNF265O9521811
Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog)ZFRQ96KR111
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15)AGPAT1 G15Q9994310
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Pancreas-enriched phospholipase C) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)PLCE1 KIAA1516 PLCE PPLCQ9P21210
14-3-3 protein zeta/delta (Fragment)YWHAZE7ESK710
14-3-3 protein zeta/delta (Fragment)YWHAZE5RGE110
28S ribosomal protein S26, mitochondrial (MRP-S26) (S26mt) (28S ribosomal protein S13, mitochondrial) (MRP-S13) (S13mt) (Mitochondrial small ribosomal subunit protein mS26)MRPS26 C20orf193 RPMS13Q9BYN810
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2) (Mitochondrial large ribosomal subunit protein uL2m)MRPL2 CGI-22Q5T65310
39S ribosomal protein L39, mitochondrial (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5) (Mitochondrial large ribosomal subunit protein mL39)MRPL39 C21orf92 MRPL5 RPML5 MSTP003 PRED22Q9NYK510
39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL)MRPL46 C15orf4 LIECG2Q9H2W610
4F2 cell-surface antigen heavy chainSLC3A2F5GZI010
60S acidic ribosomal protein P0 (Fragment)0Q53HW210
60S ribosomal protein L10RPL10F8W7C610
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