EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
HEAT repeat-containing protein 3HEATR3Q7Z4Q210
Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit]HPSE HEP HPA HPA1 HPR1 HPSE1 HSE1Q9Y25110
Hermansky-Pudlak syndrome 3 proteinHPS3Q969F910
Histone H2BHIST1H2BN hCG_1743059U3KQK010
Histone H2B0B4DR5210
HLA class I histocompatibility antigen, B-50 alpha chain (Bw-50) (HLA class I histocompatibility antigen, B-21 alpha chain) (MHC class I antigen B*50)HLA-B HLABP3048810
HLA class I histocompatibility antigen, Cw-8 alpha chain (MHC class I antigen Cw*8)HLA-C HLACP3050510
HLA class II histocompatibility antigen, DR beta 4 chain (MHC class II antigen DRB4)HLA-DRB4P1376210
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)HIF1AN FIH1Q9NWT610
Immunoglobulin heavy variable 2-70 (Ig heavy chain V-II region COR) (Ig heavy chain V-II region DAW) (Ig heavy chain V-II region OU) (Ig heavy chain V-II region SESS)IGHV2-70P0181410
Immunoglobulin heavy variable 3-20IGHV3-20A0A0C4DH3210
Immunoglobulin lambda variable 1-51 (Ig lambda chain V-I region BL2) (Ig lambda chain V-I region EPS) (Ig lambda chain V-I region NEW) (Ig lambda chain V-I region NIG-64)IGLV1-51P0631610
Importin subunit beta-1 (Fragment)KPNB1J3QRG410
Importin-5 (Fragment)IPO5C9JZD810
IQ motif containing GTPase activating protein 1IQGAP1A4QPB010
Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)0B2R5M810
Keratin, type II cytoskeletal 8 (Fragment)KRT8F8VP6710
Killer cell lectin-like receptor subfamily G member 2 (C-type lectin domain family 15 member B)KLRG2 CLEC15BA4D1S010
Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A)KIF18A OK/SW-cl.108Q8NI7710
Kinesin-like protein KIF27KIF27Q86VH210
Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET)KIFC1 HSET KNSL2Q9BW1910
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)NDC80 HEC HEC1 KNTC2O1477710
Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C]LTF GIG12 LFA8K9U810
Leucine-rich repeat-containing protein 17 (p37NB)LRRC17 P37NB UNQ3076/PRO9909Q8N6Y210
Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)LRRC4B LRIG4Q9NT9910
Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)LIFRP4270210
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)FCGR2A CD32 FCG2 FCGR2A1 IGFR2P1231810
Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)LRP4 KIAA0816 LRP10 MEGF7O7509610
Maestro heat-like repeat-containing protein family member 2B (HEAT repeat-containing protein 7B2) (Sperm PKA-interacting factor) (SPIF)MROH2B HEATR7B2Q7Z74510
MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)MPP2 DLG2Q1416810
Maltase-glucoamylase, intestinalMGAME7ER4510
Mammaglobin-B (Lacryglobin) (Lipophilin-C) (Mammaglobin-2) (Secretoglobin family 2A member 1)SCGB2A1 LIPHC MGB2 UGB3O7555610
MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor)MADD DENN IG20 KIAA0358Q8WXG610
Matrilin-3MATN3O1523210
Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2)MMP15P5151110
Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1)MED31 SOH1 CGI-125Q9Y3C710
Mesoderm-specific transcript homolog protein (EC 3.-.-.-) (Paternally-expressed gene 1 protein)MEST PEG1Q5EB5210
Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein)MTSS1 KIAA0429 MIMO4331210
MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2)MOB2 HCCA2Q70IA610
Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)SLC16A10 MCT10 TAT1Q8TF7110
Multifunctional methyltransferase subunit TRM112-like proteinTRMT112F5GX7710
Multiple PDZ domain protein (Multi-PDZ domain protein 1)MPDZ MUPP1O7597010
Myelin-associated neurite-outgrowth inhibitor (Mani) (p20)FAM168B KIAA0280L MANIA1KXE410
Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2)MYH2 MYHSA2Q9UKX210
Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE)MYH3P1105510
N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)NAALAD2Q9Y3Q010
N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (EC 3.5.1.-) (EC 4.3.-.-) (Peptidase M20 domain-containing protein 1)PM20D1Q6GTS810
Nebulette (Actin-binding Z-disk protein)NEBL LNEBLO7604110
NEDD4-binding protein 1 (N4BP1)N4BP1 KIAA0615O7511310
Neuroblastoma breakpoint family member 3 (Protein AE2) (Protein SHIIIa4)NBPF3 L7Q9H09410
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)NEFM NEF3 NFMP0719710
Neurotrimin (hNT) (IgLON family member 2)NTM IGLON2 NT UNQ297/PRO337Q9P12110
NKG2D ligand 3 (N2DL-3) (NKG2DL3) (ALCAN-gamma) (Retinoic acid early transcript 1N)ULBP3 N2DL3 RAET1NQ9BZM410
Nuclear fragile X mental retardation-interacting protein 2 (82 kDa FMRP-interacting protein) (82-FIP) (Cell proliferation-inducing gene 1 protein) (FMRP-interacting protein 2)NUFIP2 KIAA1321 PIG1Q7Z41710
Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein)NR2C2AP TRA16Q86WQ010
O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein)SEPSECS TRNP48Q9HD4010
Obg-like ATPase 1OLA1J3KQ3210
Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3)OSCARQ8IYS510
Palmitoleoyl-protein carboxylesterase NOTUM (EC 3.1.1.98) (hNOTUM)NOTUM OK/SW-CL.30Q6P98810
Paralemmin-3PALM3A6NDB910
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)PRF1 PFPP1422210
Pericentrin (Kendrin) (Pericentrin-B)PCNT KIAA0402 PCNT2O9561310
Peroxiredoxin 2, isoform CRA_a (Peroxiredoxin-2)PRDX2 hCG_172488A6NIW510
Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1)PEX1O4393310
Peroxisome proliferator activated receptor interacting complex proteinPRIC295E1NZA110
Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP)PGM5 PGMRPQ1512410
Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2)PLD2O1493910
Phytanoyl-CoA hydroxylase-interacting protein-likePHYHIPL KIAA1796 UNQ6309/PRO20934Q96FC710
Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein)PLEKHO1 CKIP1 OC120 HQ0024cQ53GL010
PodocanPODN SLRR5A UNQ293/PRO332Q7Z5L710
Polyadenylate-binding protein 1-likePABPC1L C20orf119Q4VXU210
Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)POLDIP2 PDIP38 POLD4 HSPC017Q9Y2S710
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146)WDR33 WDC146Q9C0J810
Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49)DDX49Q9Y6V710
Probable ATP-dependent RNA helicase DDX5DDX5J3KTA410
Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2)PNKD KIAA1184 MR1 TAHCCP2 FKSG19 UNQ2491/PRO5778Q8N49010
Programmed cell death 6-interacting protein (Fragment)PDCD6IPC9IZF910
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)PCCBP0516610
Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase)PTGIS CYP8 CYP8A1Q1664710
Proteasome endopeptidase complex (EC 3.4.25.1)PSMA1F5GX1110
Protein ABHD16A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5) (Protein G5)ABHD16A BAT5 G5 NG26 PP199O9587010
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)CNPY3 CTG4A ERDA5 PRAT4A TNRC5 HSPC084 UNQ1934/PRO4409Q9BT0910
Protein crumbs homolog 1CRB1P8227910
Protein dispatched homolog 2DISP2 C15orf36 DISPB KIAA1742 LINC00594A7MBM210
Protein DJ-1PARK7K7ELW010
Protein FRG1 (FSHD region gene 1 protein)FRG1Q1433110
Protein NOXP20 (Nervous system overexpressed protein 20) (Protein FAM114A1)FAM114A1 NOXP20Q8IWE210
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)PPP1R12C LENG3 MBS85Q9BZL410
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)PBRM1 BAF180 PB1Q86U8610
Protein quaking (Hqk) (HqkI)QKI HKQQ96PU810
Protein Shroom2 (Apical-like protein) (Protein APXL)SHROOM2 APXLQ1379610
Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3)SBNO1 MOP3A3KN8310
Proteinase-activated receptor 1 (PAR-1) (Coagulation factor II receptor) (Thrombin receptor)F2R CF2R PAR1 TRP2511610
Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9)RBBP9 BOG RBBP10O7588410
Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein)ASPDHA6ND9110
Putative uncharacterized protein DKFZp434K0126 (Fragment)DKFZp434K0126Q9NTC410
Putative uncharacterized protein DKFZp564O1822 (Fragment)DKFZp564O1822Q9UG8510
Putative uncharacterized protein DKFZp686I04196 (Fragment)DKFZp686I04196Q6N09310
Putative uncharacterized protein DKFZp686I15196DKFZp686I15196Q6N09610
Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Protein 4P11) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog)CRYZL1 4P11O9582510
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