EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
40S ribosomal protein S5 (Fragment)RPS5M0R0F09
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)PRKAA2 AMPK AMPK2P546469
5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)PRKAB2O437419
5'-nucleotidase (5'-nucleotidase, ecto (CD73), isoform CRA_c) (NT5E protein)NT5E hCG_401111Q96B609
5'-nucleotidase (Fragment)NT5EH0Y3X59
60S acidic ribosomal protein P2 (Fragment)RPLP2H0YDD89
60S ribosomal protein L7a (Ribosomal protein L7a)RPL7A RP11-244N20.10-005Q5T8U29
Abelson tyrosine-protein kinase 2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)ABL2 ABLL ARGP426849
Actin filament-associated protein 1-like 2 (AFAP1-like protein 2)AFAP1L2 KIAA1914 XB130Q8N4X59
Actin, cytoplasmic 1 (Fragment)ACTBC9JTX59
Actin, cytoplasmic 2 (Fragment)ACTG1I3L3R29
Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP)RPS19BP1 AROSQ86WX39
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)ARL4C ARL7P565599
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)AFF4 AF5Q31 MCEF HSPC092Q9UHB79
Alpha-actinin-1 (Fragment)ACTN1G3V2W49
Alpha-actinin-1 (Fragment)ACTN1H0YJ119
Alpha-actinin-4 (Fragment)ACTN4H7C1449
Alpha-actinin-4 (Fragment)ACTN4K7EJH89
Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Erythrocyte plasma membrane 50 kDa glycoprotein) (Rh50A) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (Rhesus blood group-associated ammonia channel) (Rhesus blood group-associated glycoprotein) (CD antigen CD241)RHAG RH50Q020949
Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF)AREG AREGB SDGFP155149
Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16)ANAPC16 C10orf104 CENP-27Q96DE59
Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein)ANKRD12 ANCO2 KIAA0874Q6UB989
Ankyrin repeat domain-containing protein 36AANKRD36 ANKRD36A KIAA1641 UNQ2430/PRO499A6QL649
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)ANK2Q014849
AnnexinANXA6E5RK699
Annexin (Fragment)ANXA2H0YKL99
Annexin (Fragment)ANXA2H0YNP59
Annexin (Fragment)ANXA2H0YKS49
Annexin A10 (Annexin-10) (Annexin-14)ANXA10 ANX14Q9UJ729
Anterior gradient protein 3 (AG-3) (AG3) (hAG-3) (Anterior gradient 3 homolog) (Breast cancer membrane protein 11) (Protein disulfide isomerase family A, member 18)AGR3 BCMP11 PDIA18 UNQ642/PRO1272Q8TD069
Apolipoprotein A-V (Apo-AV) (ApoA-V) (Apolipoprotein A5) (Regeneration-associated protein 3)APOA5 RAP3 UNQ411/PRO773Q6Q7889
Apolipoprotein D (Fragment)APODC9JF179
Arachidonate 15-lipoxygenase (15-LOX) (15-LOX-1) (EC 1.13.11.33) (12/15-lipoxygenase) (Arachidonate 12-lipoxygenase, leukocyte-type) (12-LOX) (EC 1.13.11.31) (Arachidonate omega-6 lipoxygenase)ALOX15 LOG15P160509
Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)ATE1O952609
ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8)ABCC11 MRP8Q96J669
ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP)ABCD1 ALDP338979
ATP-binding cassette, sub-family B (MDR/TAP), member 1ABCB1A1L4719
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)DHX8 DDX8Q145629
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)CD22 SIGLEC2P202739
Band 4.1-like protein 4B (FERM-containing protein CG1) (Protein EHM2)EPB41L4B EHM2 LULU2Q9H3299
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]MTHFD2 NMDMCP139959
BRO1 domain-containing protein BROX (Fragment)BROXQ5VW339
BTB/POZ domain-containing protein KCTD14KCTD14Q9BQ139
BTB/POZ domain-containing protein KCTD5KCTD5Q9NXV29
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)CCR1 CMKBR1 CMKR1 SCYAR1P322469
C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip)CMIP KIAA1694 TCMIPQ8IY229
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)ORAI1 CRACM1 TMEM142AQ96D319
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)CALCOCO2 NDP52Q131379
Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)CAMKK2 CAMKKB KIAA0787Q96RR49
Calmodulin-regulated spectrin-associated protein 1CAMSAP1Q5T5Y39
Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM)CAPN6 CALPM CANPXQ9Y6Q19
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)PDE4D DPDE3Q084999
Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0)CHST3Q7LGC89
Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3)CLPB HSP78 SKD3Q9H0789
Catenin (Cadherin-associated protein), alpha 1, 102kDa, isoform CRA_a (Catenin alpha-1)CTNNA1 hCG_1782385G3XAM79
Catenin beta-1CTNNB1B5BU289
Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)CTSK CTSO CTSO2P432359
CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180)CD180 LY64 RP105Q994679
CD44 antigen (Fragment)CD44H0YE409
cDNA FLJ10153 fis, clone HEMBA1003417, highly similar to BAG family molecular chaperone regulator 20B3KM369
cDNA FLJ13778 fis, clone PLACE4000431, highly similar to H.sapiens U5 snRNP-specific 200kD protein0Q9H8B99
cDNA FLJ16785 fis, clone NT2RI2015342, highly similar to Solute carrier family 2, facilitated glucose transporter member 10B3KVN09
cDNA FLJ20242 fis, clone COLF63690Q9NXI09
cDNA FLJ38578 fis, clone HCHON2007674, highly similar to NUCLEOLIN0B3KTP99
cDNA FLJ52062, highly similar to Erythrocyte band 7 integral membrane protein0B4E2V59
cDNA FLJ54184, highly similar to Tropomyosin alpha-4 chain0B4DVY29
cDNA FLJ54588, highly similar to Major vault protein0B4DDR29
cDNA FLJ54776, highly similar to Cell division control protein 42 homolog0B4E1U99
cDNA FLJ57227, highly similar to Isocitrate dehydrogenase0B4DXS49
cDNA FLJ60424, highly similar to Junction plakoglobin0B4DE599
cDNA FLJ61188, highly similar to Basigin0B4DY239
cDNA FLJ61290, highly similar to Neutral alpha-glucosidase AB0B4DJ309
cDNA FLJ76789, highly similar to Homo sapiens methionine-tRNA synthetase (MARS), mRNA0A8K4929
cDNA, FLJ92904, highly similar to Homo sapiens casein kinase 2, alpha 1 polypeptide (CSNK2A1), mRNA0B2R6D79
cDNA, FLJ93166, highly similar to Homo sapiens heat shock 70kDa protein 6 (HSP70B') (HSPA6), mRNA0B2R6X59
cDNA, FLJ96428, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA0B2RD279
Cell division cycle protein 123 homolog (Protein D123) (HT-1080) (PZ32)CDC123 C10orf7 D123O757949
Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1)CDCA3 C8 GRCC8 TOME1Q996189
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)CEP290 BBS14 KIAA0373 NPHP6O150789
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)CEP250 CEP2 CNAP1Q9BV739
CeruloplasminCPE9PFZ29
cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)PRKG2 PRKGR2Q132379
Charged multivesicular body protein 7 (Chromatin-modifying protein 7)CHMP7Q8WUX99
Chloride intracellular channel proteinCLIC4 hCG_24047Q6FIC59
Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82)CHKA CHK CKIP357909
Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5)CHD5 KIAA0444Q8TDI09
Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64)CSTF2T KIAA0689Q9H0L49
Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein) (Cisplatin resistance-related protein 9) (CRR9p)CLPTM1L CRR9Q96KA59
Clusterin (Fragment)CLUH0YC359
Cofilin-1 (Fragment)CFL1E9PLJ39
Coiled-coil domain-containing protein 73 (Sarcoma antigen NY-SAR-79)CCDC73Q6ZRK69
Collagen alpha-1(XXII) chainCOL22A1Q8NFW19
Collagen alpha-1(XXIV) chainCOL24A1Q17RW29
Collagen alpha-6(IV) chainCOL4A6Q140319
Collagen alpha-6(VI) chainCOL6A6A6NMZ79
COMM domain-containing protein 7COMMD7 C20orf92Q86VX29
Contactin-2 (Axonal glycoprotein TAG-1) (Axonin-1) (Transient axonal glycoprotein 1) (TAX-1)CNTN2 AXT TAG1 TAX1Q022469
Copine-1 (HCG38213, isoform CRA_b)CPNE1 hCG_38213B0QZ189
cTAGE family member 5 (Protein cTAGE-5) (Meningioma-expressed antigen 6/11)CTAGE5 MEA11 MEA6 MGEA11 MGEA6O153209
CTP synthase (EC 6.3.4.2) (UTP--ammonia ligase)0B4DMB59
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