EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta)LAPTM4B PSEC0001Q86VI49
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)LAPTM5 KIAA0085Q135719
Lysosomal-trafficking regulator (Beige homolog)LYST CHS CHS1Q996989
Major vault protein (Fragment)MVPH3BRL29
MARCKS protein (Fragment)MARCKSQ6NVI19
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)MED18Q9BUE09
Mesoderm development candidate 1MESDC1Q9H1K69
Metastasis-associated protein MTA3MTA3 KIAA1266Q9BTC89
MICOS complex subunit MIC10 (Mitochondrial inner membrane organizing system protein 1)MINOS1 C1orf151 MIC10Q5TGZ09
Microfibrillar-associated protein 1MFAP1P550819
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2)ALDH1L2Q3SY699
Mitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2)TIMM8B DDP2 DDPL TIM8BQ9Y5J99
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)MAPK8 JNK1 PRKM8 SAPK1 SAPK1CP459839
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)MAD2L1 MAD2Q132579
Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)SPEN KIAA0929 MINT SHARPQ96T589
Mucolipin-1 (MG-2) (Mucolipidin)MCOLN1 ML4 MSTP080Q9GZU19
Multifunctional protein ADE2 (Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_b)PAICS hCG_2027161D6RF629
Myoferlin (Fragment)MYOFH0YD149
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)MYH6 MYHCAP135339
Myotubularin-related protein 6 (EC 3.1.3.-)MTMR6Q9Y2179
N-alpha-acetyltransferase 40 (EC 2.3.1.257) (N-acetyltransferase 11) (N-alpha-acetyltransferase D) (NatD) (hNatD) (Protein acetyltransferase 1)NAA40 NAT11 PATT1Q86UY69
Na(+)/H(+) exchange regulatory cofactor NHE-RF0B2R6A39
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa)NDUFAF4 C6orf66 HRPAP20 HSPC125 My013Q9P0329
NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)NUB1 NYREN18Q9Y5A79
Neurensin-2NRSN2 C20orf98Q9GZP19
Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1)PCSK1 NEC1P291209
Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II)NPTX2P479729
NKG2D ligand 2 (N2DL-2) (NKG2DL2) (ALCAN-alpha) (Retinoic acid early transcript 1H) (UL16-binding protein 2)ULBP2 N2DL2 RAET1H UNQ463/PRO791Q9BZM59
Nodal modulator 3 (pM5 protein 3)NOMO3P698499
NogginNOGQ132539
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)NDEL1 EOPA MITAP1 NUDELQ9GZM89
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)NFIC NFIP086519
Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)NCOA7 ERAP140 ESNA1 Nbla00052 Nbla10993Q8NI089
Nucleolar protein 14 (Nucleolar complex protein 14)NOP14 C4orf9 NOL14 RES4-25P783169
Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB)OSMR OSMRBQ996509
Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit)OSTM1 GL HSPC019 UNQ6098/PRO21201Q86WC49
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)OTUD7B ZA20D1Q6GQQ99
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (C-type lectin domain family 8 member A) (Lectin-like oxidized LDL receptor 1) (LOX-1) (Lectin-like oxLDL receptor 1) (hLOX-1) (Lectin-type oxidized LDL receptor 1) [Cleaved into: Oxidized low-density lipoprotein receptor 1, soluble form]OLR1 CLEC8A LOX1P783809
Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1BQ9BXW69
P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P)SELP GMRP GRMPP161099
Peptidase inhibitor 16 (PI-16) (Cysteine-rich secretory protein 9) (CRISP-9) (PSP94-binding protein)PI16 CRISP9 PSPBP PSEC0164 UNQ289/PRO328Q6UXB89
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)PPIAF8WE659
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) (Spliceosome-associated cyclophilin)PPWD1 KIAA0073Q96BP39
Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein)PEX19 HK33 PXF OK/SW-cl.22P408559
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)PHIP WDR11Q8WWQ09
PHD finger protein 6 (PHD-like zinc finger protein)PHF6 CENP-31 KIAA1823Q8IWS09
Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)PIGU CDC91L1 PSEC0205 UNQ3055/PRO9875Q9H4909
Phosphoinositide-3-kinase-interacting protein 1 (Kringle domain-containing protein HGFL)PIK3IP1 HGFLQ96FE79
Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-)PHYHD1Q5SRE79
Platelet factor 4 variant (C-X-C motif chemokine 4 variant) (CXCL4L1) (PF4alt) (PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74)]PF4V1 CXCL4V1 SCYB4V1P107209
Plexin-B3PLXNB3 KIAA1206 PLXN6Q9ULL49
Poly [ADP-ribose] polymerase 10 (PARP-10) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 10) (ARTD10)PARP10Q53GL79
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)PKD2 TRPP2Q135639
Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR)POLDIP3 KIAA1649 PDIP46Q9BY779
Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4)PBX4Q9BYU19
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)CDC40 EHB3 PRP17 PRPF17O605089
Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)RBM22 ZC3H16 199G4Q9NW649
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)]NPYP013039
Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)HELZ DRHC KIAA0054P426949
Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185)TARBP1 TRM3 TRP185Q133959
Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377)ZDHHC1 C16orf1 ZNF377Q8WTX99
Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein) (Haponin)EIF1ADQ8N9N89
Probable threonine--tRNA ligase 2, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like protein 2)TARSL2A2RTX59
Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2)PNRC1 PROL2Q127969
Proteasome subunit alpha type (EC 3.4.25.1)PSMA4H0YLS69
Proteasome subunit alpha type (EC 3.4.25.1)PSMA6G3V3I19
Proteasome subunit beta type (EC 3.4.25.1) (Fragment)PSMA4H0YKT89
Protein ABHD12B (EC 3.-.-.-) (Abhydrolase domain-containing protein 12B) (Alpha/beta hydrolase domain-containing protein 12B)ABHD12B C14orf29Q7Z5M89
Protein ALEX (Alternative gene product encoded by XL-exon)GNAS GNAS1P849969
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)DR1Q016589
Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1)AHCTF1 ELYS TMBS62 MSTP108Q8WYP59
Protein FAM207AFAM207A C21orf70 PRED56Q9NSI29
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)HEXIM1 CLP1 EDG1 HIS1 MAQ1O949929
Protein HGH1 homologHGH1 C8orf30A C8orf30B FAM203A FAM203BQ9BTY79
Protein HikeshiHIKESHI C11orf73 HSPC138 HSPC179 HSPC248Q53FT39
Protein phosphatase 1H (EC 3.1.3.16)PPM1H ARHCL1 KIAA1157 URCC2Q9ULR39
Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)SSH3 SSH3LQ8TE779
Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)S100A7A S100A15 S100A7L1Q86SG59
Protein sidekick-2SDK2 KIAA1514Q58EX29
Protein transport protein Sec31ASEC31AD6REX39
Protein unc-13 homolog B (Munc13-2) (munc13)UNC13B UNC13O147959
Protein-arginine deiminase type-2 (EC 3.5.3.15) (PAD-H19) (Peptidylarginine deiminase II) (Protein-arginine deiminase type II)PADI2 KIAA0994 PAD2 PDI2Q9Y2J89
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)PTK2B FAK2 PYK2 RAFTKQ142899
Protocadherin gamma-B5 (PCDH-gamma-B5)PCDHGB5Q9Y5G09
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)]TGFAP011359
Pumilio homolog 1 (HsPUM) (Pumilio-1)PUM1 KIAA0099 PUMH1Q146719
Putative protein C3P1C3P1Q6ZMU19
Putative uncharacterized protein DKFZp686E1899DKFZp686E1899Q5HYL69
Putative uncharacterized protein DKFZp686L19235DKFZp686L19235Q6MZV69
Putative uncharacterized protein DKFZp686M24218DKFZp686M24218Q6MZX79
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)PDPR KIAA1990Q8NCN59
Pyruvate kinase PKM (Fragment)PKMH3BUW19
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)CHML REP2P263749
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)RAF1 RAFP040499
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)RALGAPA1 GARNL1 KIAA0884 TULIP1Q6GYQ09
Ran-binding protein 3 (RanBP3)RANBP3Q9H6Z49
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)RASAL2 NGAPQ9UJF29
Ras homolog enriched in brainRHEBQ6NZ619
Ras-related protein Rab-19RAB19 RAB19BA4D1S59
Ras-related protein Rab-7bRAB7BQ96AH89
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