EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Reactive oxygen species modulator 1 (ROS modulator 1) (Epididymis tissue protein Li 175) (Glyrichin) (Mitochondrial targeting GxxxG motif protein) (MTGM) (Protein MGR2 homolog)ROMO1 C20orf52P606029
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)RIMS2 KIAA0751 RAB3IP3 RIM2Q9UQ269
Regulator of G-protein signaling 17 (RGS17)RGS17 RGSZ2Q9UGC69
Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6)ARHGEF6 COOL2 KIAA0006 PIXAQ150529
Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)RHOD ARHDO002129
Ribonuclease 7 (RNase 7) (EC 3.1.27.-) (Skin-derived antimicrobial protein 2) (SAP-2)RNASE7 UNQ2516/PRO6006Q9H1E19
Ribosomal protein L19RPL19J3QR099
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)RPS6KA2 MAPKAPK1C RSK3Q153499
Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)MRRFQ96E119
RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)RBM10 DXS8237E GPATC9 GPATCH9 KIAA0122P981759
RNA-binding protein 12B (RNA-binding motif protein 12B)RBM12BQ8IXT59
Roundabout homolog 2ROBO2 KIAA1568Q9HCK49
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)RYR1 RYDRP218179
SEC14-like protein 4 (Tocopherol-associated protein 3)SEC14L4 TAP3Q9UDX39
Selenoprotein O (SelO)SELENOO SELOQ9BVL49
Semaphorin-4A (Semaphorin-B) (Sema B)SEMA4A SEMAB SEMB UNQ783/PRO1317Q9H3S19
Septin 10, isoform CRA_c (Septin-10)SEPT10 hCG_27895B5ME979
Septin-2SEPT2B5MCX39
Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17)SRRQ9GZT49
Serine--tRNA ligase, cytoplasmicSARSQ5T5C79
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)STK11 LKB1 PJSQ158319
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform)PPP3CB CALNA2 CALNB CNA2P162989
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)PPP6R2 KIAA0685 PP6R2 SAPS2O751709
SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains)SH3PXD2A FISH KIAA0418 SH3MD1 TKS5Q5TCZ19
Similar to RAB22A, member RAS oncogene family (Fragment)0Q96IY79
Similar to ribosomal protein L23 (Fragment)0Q9BTQ79
SLIT and NTRK-like protein 1 (Leucine-rich repeat-containing protein 12)SLITRK1 KIAA1910 LRRC12 UNQ233/PRO266Q96PX89
Small acidic proteinSMAP C11orf58O001939
Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (hSGLT4) (Solute carrier family 5 member 9)SLC5A9 SGLT4Q2M3M29
Sodium/potassium-transporting ATPase subunit betaATP1B3 hCG_19938D3DNF99
Solute carrier family 2, facilitated glucose transporter member 9 (Glucose transporter type 9) (GLUT-9)SLC2A9 GLUT9Q9NRM09
Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (hRFT2)SLC52A3 C20orf54 RFT2 RFVT3Q9NQ409
StAR-related lipid transfer protein 9 (START domain-containing protein 9) (StARD9)STARD9 KIAA1300Q9P2P69
Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)SPEG APEG1 KIAA1297Q157729
Synaptonemal complex protein 1 (SCP-1) (Cancer/testis antigen 8) (CT8)SYCP1 SCP1Q154319
Synaptopodin-2 (Genethonin-2) (Myopodin)SYNPO2Q9UMS69
Synaptosomal-associated protein (Fragment)SNAP23H3BM389
Synaptotagmin-11 (Synaptotagmin XI) (SytXI)SYT11 KIAA0080Q9BT889
Synaptotagmin-like protein 5SYTL5 SLP5Q8TDW59
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)STXBP4Q6ZWJ19
T-cell surface glycoprotein CD1b (CD antigen CD1b)CD1BP290169
T-cell surface glycoprotein CD3 delta chain (T-cell receptor T3 delta chain) (CD antigen CD3d)CD3D T3DP042349
T-complex protein 1 subunit alphaTCP1E7EQR69
T-complex protein 1 subunit delta0B7Z2Z89
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)MLST8 GBL LST8Q9BVC49
TBC1 domain family member 23 (HCV non-structural protein 4A-transactivated protein 1)TBC1D23 NS4ATP1Q9NUY89
Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1)TOR1AIP2 IFRG15 LULL1Q8NFQ89
Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A)TOR3A ADIRQ9H4979
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)YAP1 YAP65P469379
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)CTCFP497119
Transmembrane channel-like protein 7TMC7Q7Z4029
Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2)TMC8 EVER2 EVIN2Q8IU689
Transmembrane protein 163TMEM163Q8TC269
Tripartite motif-containing protein 72 (Mitsugumin-53) (Mg53)TRIM72 MG53Q6ZMU59
Tumor necrosis factor receptor superfamily member 19L (Receptor expressed in lymphoid tissues)RELT TNFRSF19LQ969Z49
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)JAK2O606749
Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)TIE1 TIEP355909
U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)MPHOSPH10 MPP10O005669
Ubiquitin A-52 residue ribosomal protein fusion product 1 (Ubiquitin A-52 residue ribosomal protein fusion product 1, isoform CRA_a) (cDNA, FLJ95576, Homo sapiens ubiquitin A-52 residue ribosomal protein fusionproduct 1 (UBA52), mRNA)UBA52 hCG_37048Q3MIH39
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)USP4 UNP UNPHQ131079
Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (DUBA-8) (HIV-1-induced protease 7) (HIN-7) (HsHIN7) (OTU domain-containing protein 2)YOD1 DUBA8 HIN7 OTUD2 PRO0907Q5VVQ69
Ubiquitin-60S ribosomal protein L40 (Fragment)UBA52M0R2S19
Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)UBAP1 NAG20Q9NZ099
Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)UBLCP1Q8WVY79
Uncharacterized protein0A8K0089
Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1)C18orf8 MIC1Q96DM39
Unconventional myosin-IbMYO1BE9PDF69
Unconventional myosin-IcMYO1CF5H6E29
Unconventional myosin-XV (Unconventional myosin-15)MYO15A MYO15Q9UKN79
Uroplakin-3b (UP3b) (Uroplakin IIIb) (UPIIIb) (p35)UPK3BQ9BT769
Voltage-dependent R-type calcium channel subunit alpha-1E (Brain calcium channel II) (BII) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Voltage-gated calcium channel subunit alpha Cav2.3)CACNA1E CACH6 CACNL1A6Q158789
von Willebrand factor A domain-containing protein 8VWA8 KIAA0564A3KMH19
VPS9 domain-containing protein 1 (Protein ATP-BL)VPS9D1 ATPBL C16orf7Q9Y2B59
WolframinWFS1O760249
X antigen family member 1 (XAGE-1) (Cancer/testis antigen 12.1) (CT12.1) (G antigen family D member 2)XAGE1A GAGED2 XAGE1; XAGE1B; XAGE1C; XAGE1D; XAGE1EQ9HD649
YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113)YLPM1 C14orf170 ZAP3P497509
Zinc finger CCCH domain-containing protein 11AZC3H11A KIAA0663 ZC3HDC11AO751529
Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN)ZC3H7B KIAA1031Q9UGR29
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)PDP1 PDP PPM2CQ9P0J19
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase)PIKFYVE KIAA0981 PIP5K3Q9Y2I78
14-3-3 protein epsilon (Fragment)YWHAEK7EM208
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)OASL TRIP14Q156468
26S protease regulatory subunit 6APSMC3R4GNH38
28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38) (Mitochondrial small ribosomal subunit protein mS31)MRPS31 IMOGN38Q926658
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)PDPK1 PDK1O155308
39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22) (39S ribosomal protein L25, mitochondrial) (L25mt) (MRP-L25) (Mitochondrial large ribosomal subunit protein uL22m)MRPL22 MRPL25 RPML25 HSPC158Q9NWU58
39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55) (Mitochondrial large ribosomal subunit protein bL31m) (Mitochondrial large ribosomal subunit protein mL55)MRPL55 UNQ5835/PRO19675Q7Z7F78
40S ribosomal protein S4RPS4X hCG_18634B2R4918
4F2 cell-surface antigen heavy chain (Fragment)SLC3A2H0YFS28
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)XRN1 SEP1Q8IZH28
5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p)PRKAG2Q9UGJ08
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]PFKFB3Q168758
60S ribosomal protein L13RPL13 hCG_1723872A8K4C88
60S ribosomal protein L9 (Fragment)RPL9D6RAN48
7-methylguanosine phosphate-specific 5'-nucleotidase (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC 3.1.3.5) (N(7)-methylguanylate 5'-phosphatase)NT5C3B NT5C3LQ969T78
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-)ADAMTS15Q8TE588
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI)ADAMTS2 PCINP PCPNIO954508
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1)ADAMTS4 KIAA0688 UNQ769/PRO1563O751738
A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)AKAP1 AKAP149 PRKA1Q926678
Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin)ABLIM1 ABLIM KIAA0059 LIMAB1O146398
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