EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Activated RNA polymerase II transcription cofactor 4 variant (Fragment)0Q59G248
Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4)TRIP4Q156508
Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)ASCC1 CGI-18Q8N9N28
Acyl-protein thioesterase 1 (Fragment)LYPLA1E5RGR08
ADAM10 proteinADAM10A0AV888
ADAMTS-like protein 2 (ADAMTSL-2)ADAMTSL2 KIAA0605Q86TH18
ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)ARFGAP3 ARFGAP1Q9NP618
ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1)ARL2BP BART BART1Q9Y2Y08
AfadinAFDNA8MQ028
Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like)AKR7L AFAR3 AKR7A4Q8NHP18
Aladin (Adracalin)AAAS ADRACALA GL003Q9NRG98
Aldo-keto reductase family 1 member B15 (EC 1.1.1.-) (Estradiol 17-beta-dehydrogenase AKR1B15) (EC 1.1.1.62)AKR1B15C9JRZ88
Alpha-actinin-1 (Fragment)ACTN1G3V2N58
Alpha-actinin-1 (Fragment)ACTN1G3V5M48
Alpha-L-iduronidase (EC 3.2.1.76)IDUAP354758
Aminopeptidase BRNPEPA6NKB88
Amyloid-like protein 1 (APLP) (APLP-1) [Cleaved into: C30]APLP1P516938
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)ANAPC2 APC2 KIAA1406Q9UJX68
Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.-)ANKIB1 KIAA1386Q9P2G18
Ankyrin repeat and SAM domain-containing protein 1A (Odin)ANKS1A ANKS1 KIAA0229 ODINQ926258
AnnexinANXA5D6RBE98
Annexin (Fragment)ANXA11Q6ICS08
Annexin (Fragment)ANXA2H0YN428
Annexin (Fragment)ANXA2H0YKZ78
AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP)AP3B2Q133678
Apoptotic protease-activating factor 1 (APAF-1)APAF1 KIAA0413O147278
Aquaporin-5 (AQP-5)AQP5P550648
ARHG protein (Ras homolog gene family, member G (Rho G)) (Ras homolog gene family, member G (Rho G), isoform CRA_a) (Fragment)ARHG RHOG hCG_16162Q6ICQ88
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)ATAD5 C17orf41 FRAG1Q96QE38
Autophagy-related protein 2 homolog AATG2A KIAA0404Q2TAZ08
B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)CD19P153918
Basement membrane-specific heparan sulfate proteoglycan core protein (Fragment)HSPG2H0Y5A98
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like proteinBNIPLQ7Z4658
Beta-arrestin-2 (Arrestin beta-2)ARRB2 ARB2 ARR2P321218
Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)ENO3D3DTL28
Beta-globin (Globin A1) (Hemoglobin, beta)HBB GLNA1D9YZU58
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 1 (EC 2.8.2.-)]NDST1 HSST HSST1P528488
Brain-specific angiogenesis inhibitor 1-associated protein 2BAIAP2I3L4C28
Brain-specific angiogenesis inhibitor 1-associated protein 2 (cDNA FLJ55181, highly similar to Brain-specific angiogenesis inhibitor1-associated protein 2)BAIAP2B4DWA18
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)BCAR1 CAS CASS1 CRKASP569458
BRO1 domain-containing protein BROXBROXF5GXQ08
Bromodomain-containing protein 3 (RING3-like protein)BRD3 KIAA0043 RING3LQ150598
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)KCTD15Q96SI18
Bumetanide-sensitive Na-K-Cl cotransporter (Solute carrier family 12 (Sodium/potassium/chloride transporters), member 2, isoform CRA_b)SLC12A2 hCG_27034Q53ZR18
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)MAPK8IP3 JIP3 KIAA1066Q9UPT68
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)C5AR1 C5AR C5R1P217308
Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)CAMK4 CAMK CAMK-GR CAMKIVQ165668
Calsyntenin-2 (Alcadein-gamma) (Alc-gamma)CLSTN2 CS2Q9H4D08
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]CASP1 IL1BC IL1BCEP294668
Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein)CTNNA3Q9UI478
Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4)SLC7A4O432468
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)CNOT3 KIAA0691 LENG2 NOT3O751758
CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209)CD209 CLEC4LQ9NNX68
CD59 glycoprotein (Fragment)CD59H0YET28
CD9 antigen (Fragment)CD9F5GXT18
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)CDK5RAP2 CEP215 KIAA1633Q96SN88
CDKN2A-interacting protein (Collaborator of ARF)CDKN2AIP CARFQ9NXV68
cDNA FLJ13518 fis, clone PLACE10057990Q9H8K18
cDNA FLJ46245 fis, clone TESTI4020596, highly similar to Homo sapiens calpain 5 (CAPN5)0Q6ZRM88
cDNA FLJ54854, highly similar to Junctional adhesion molecule A0B7Z5W18
cDNA FLJ58517, highly similar to Calpain-2 catalytic subunit (EC 3.4.22.53)0B4DN778
cDNA FLJ59399, highly similar to Keratin, type II cytoskeletal 40B4DRR78
cDNA FLJ59571, highly similar to Eukaryotic translation initiation factor 4gamma 20B4DZF28
cDNA FLJ61420, highly similar to Homo sapiens olfactomedin 4 (OLFM4), mRNA0B4DV648
cDNA FLJ75066, highly similar to Homo sapiens complement component 1, r subcomponent (C1R), mRNA0A8K5J88
cDNA FLJ78448, highly similar to Homo sapiens argininosuccinate synthetase (ASS), transcript variant 1, mRNA0A8KAP98
cDNA PSEC0102 fis, clone NT2RP2003127, highly similar to Prominin-10B3KQS18
cDNA, FLJ92164, highly similar to Homo sapiens peroxiredoxin 1 (PRDX1), mRNA0B2R4P28
cDNA, FLJ93545, highly similar to Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA0B2R7P88
cDNA, FLJ93604, highly similar to Homo sapiens major histocompatibility complex, class I, A (HLA-A),mRNA0B2R7U38
cDNA, FLJ94213, highly similar to Homo sapiens pregnancy-zone protein (PZP), mRNA0B2R9508
cDNA, FLJ94640, highly similar to Homo sapiens keratin 18 (KRT18), mRNA0B2RA038
cDNA, FLJ94999, highly similar to Homo sapiens calpain 7 (CAPN7), mRNA0B2RAM28
cDNA, FLJ96627, highly similar to Homo sapiens calpain 1, (mu/I) large subunit (CAPN1), mRNA0B2RDI58
cDNA, FLJ96901, highly similar to Homo sapiens Rac GTPase activating protein 1 (RACGAP1), mRNA0B2RE348
Centrosomal protein of 104 kDa (Cep104)CEP104 KIAA0562O603088
Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)CEP131 AZI1 KIAA1118Q9UPN48
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)CEP135 CEP4 KIAA0635Q66GS98
Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein)CEP41 TSGA14Q9BYV88
Ceramide-1-phosphate transfer protein (CPTP) (Glycolipid transfer protein domain-containing protein 1) (GLTP domain-containing protein 1)CPTP GLTPD1Q5TA508
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)PRKG1 PRKG1B PRKGR1A PRKGR1BQ139768
Chaperonin containing TCP1, subunit 7 (Eta) variant (Fragment)0Q53HV28
Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (Mannosyltransferase-1) (MT-1) (hMat-1)ALG1 HMAT1 HMT1 PSEC0061 UNQ861/PRO1870Q9BT228
Chloride intracellular channel proteinCLIC1 hCG_2005611Q5SRT38
Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A)PCYT1A CTPCT PCYT1P495858
Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa)BAP18 C17orf49Q8IXM28
Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48)CDYL CDYL1Q9Y2328
Chromosome 12 open reading frame 10 (Chromosome 12 open reading frame 10, isoform CRA_b)C12orf10 hCG_23362Q86UA38
Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin)CGNL1 JACOP KIAA1749Q0VF968
Clusterin (Fragment)CLUE7ERK68
Clusterin (Fragment)CLUH0YAS88
CMRF35-like molecule 9 (CLM-9) (CD300 antigen-like family member G) (Triggering receptor expressed on myeloid cells 4) (TREM-4) (CD antigen CD300g)CD300LG CLM9 TREM4 UNQ422/PRO846Q6UXG38
Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]F8 F8CP004518
Cofilin-1CFL1E9PK258
Cofilin-1 (Fragment)CFL1E9PQB78
Coiled-coil domain-containing protein 85CCCDC85CA6NKD98
Collagen alpha-1(XII) chain (Fragment)COL12A1H0Y5N98
Collagen alpha-1(XXI) chainCOL21A1 COL1AL FP633Q96P448
Collagen alpha-3(VI) chainCOL6A3E7ENL68
Complement C4-BC4BF5GXS08
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