EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)USP6 HRP1 TRE2P351258
Ubiquitin-like protein 7 (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP) (Ubiquitin-like protein SB132)UBL7 BMSCUBP SB132Q96S828
Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-)KIAA1161Q6NSJ08
Uncharacterized proteinDKFZp686I15212Q6N0308
Uncharacterized protein KIAA0513KIAA0513O602688
Uncharacterized protein KIAA1211-likeKIAA1211L C2orf55Q6NV748
Uncharacterized protein KIAA2026KIAA2026Q5HYC28
Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)URI1 C19orf2 NNX3 PPP1R19 RMP URIO947638
UPF0606 protein KIAA1549KIAA1549Q9HCM38
UPF0668 protein C10orf76C10orf76Q5T2E68
Vacuolar fusion protein CCZ1 homolog B (Vacuolar fusion protein CCZ1 homolog-like)CCZ1B C7orf28BP867908
Vacuole membrane protein 1 (Transmembrane protein 49)VMP1 TDC1 TMEM49 HSPC292Q96GC98
Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 1) (Transformation-related gene 8 protein) (TRG-8)BNIP1 NIP1 SEC20L TRG8Q129818
Voltage-dependent anion-selective channel protein 2 (Fragment)VDAC2A0A0A0MR028
von Willebrand factor A domain-containing protein 1 (Fragment)VWA1J3QLP38
WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4) (Major epididymis-specific protein E4) (Putative protease inhibitor WAP5)WFDC2 HE4 WAP5Q145088
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)WIPF1 WASPIP WIPO435168
WASH complex subunit 2C (Vaccinia virus penetration factor) (VPEF)WASHC2C FAM21C KIAA0592Q9Y4E18
WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1)WHAMM KIAA1971 WHDC1Q8TF308
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)WDR45 WDRX1 WDRXI4 WIPI4 JM5Q9Y4848
WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog)WDR35 IFT121 KIAA1336Q9P2L08
Zinc transporter ZIP14 (Fragment)SLC39A14E5RFZ88
1,4-alpha-glucan-branching enzymeGBE1E9PGM47
1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis-specific protein) (hTSP)AKR1E2 AKR1CL2 AKRDC1Q96JD67
14-3-3 protein beta/alphaYWHABB5BU247
14-3-3 protein zeta/delta (cDNA FLJ50142, highly similar to 14-3-3 protein zeta/delta (Protein kinase Cinhibitor protein 1))YWHAZB7Z2E67
14-3-3 protein zeta/delta (cDNA, FLJ79516, highly similar to 14-3-3 protein zeta/delta)YWHAZB0AZS67
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)COQ5Q5HYK37
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-)OGFOD2Q6N0637
26S protease regulatory subunit 10B (Fragment)PSMC6H0YJC07
39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9) (Mitochondrial large ribosomal subunit protein bL9m)MRPL9Q9BYD27
40S ribosomal protein S13RPS13J3KMX57
4F2 cell-surface antigen heavy chain (Fragment)SLC3A2F5H0E27
4F2 cell-surface antigen heavy chain (Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2, isoform CRA_a)SLC3A2 hCG_2016598J3KPF37
60S ribosomal protein L13RPL13Q6NZ557
60S ribosomal protein L32 (Fragment)RPL32D3YTB17
60S ribosomal protein L7RPL7A8MUD97
A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta)AKAP7 AKAP15 AKAP18O436877
A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95)AKAP8 AKAP95O438237
Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902)CHIAQ9BZP67
Acrosin (EC 3.4.21.10) [Cleaved into: Acrosin light chain; Acrosin heavy chain]ACR ACRSP103237
Actin related protein 2/3 complex, subunit 1B, 41kDa (Actin related protein 2/3 complex, subunit 1B, 41kDa, isoform CRA_a) (cDNA, FLJ95695, Homo sapiens actin related protein 2/3 complex, subunit 1B, 41kDa(ARPC1B), mRNA)ARPC1B hCG_19475 tcag7.662A4D2757
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit)ARPC3Q2LE717
Actin-related protein 3 (cDNA FLJ51148, highly similar to Actin-like protein 3) (cDNA FLJ52434, highly similar to Actin-like protein 3) (cDNA, FLJ79112, highly similar to Actin-like protein 3) (cDNA, FLJ79295, highly similar to Actin-like protein 3)ACTR3B4DXW17
Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Adrenal gland protein AD-004) (Coilin-interacting nuclear ATPase protein) (hCINAP) (Dual activity adenylate kinase/ATPase) (AK/ATPase)AK6 CINAP AD-004 CGI-137Q9Y3D87
Adenylyl cyclase-associated protein0B4DNY37
ADP-ribosylation factor 3 (Fragment)ARF3F5H0C77
ADP-ribosylation factor 4 (Fragment)ARF4C9JPM47
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)ALKQ9UM737
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)PYGLE9PK477
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1) (Fragment)0Q59GM97
Alpha-2 globin chain (Delta globin) (HCG1745306, isoform CRA_b)HBA2 hCG_1745306D1MGQ27
Alpha-actinin-1 (Fragment)ACTN1G3V2X97
Alpha-actinin-1 (Fragment)ACTN1H0YJW37
Alpha-actinin-4 (Fragment)ACTN4K7EP197
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 4)ALKBH4 ABH4Q9NXW97
Alpha-soluble NSF attachment proteinNAPAM0R0Y27
Amino acid transporter0B7Z5617
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2AIMP2A8MU587
AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1)STAMBPL1 AMSHLP KIAA1373Q96FJ07
Ancient ubiquitous protein 1AUP1Q9Y6797
Angio-associated migratory cell proteinAAMPQ136857
AngiomotinAMOT KIAA1071Q4VCS57
Ankyrin repeat domain-containing protein 22ANKRD22Q5VYY17
AnnexinANXA3D6RA827
Annexin (Fragment)0Q59EP17
Annexin (Fragment)ANXA2H0YMD07
Annexin A11 (Fragment)ANXA11H0Y6E17
AP-5 complex subunit beta-1 (Adaptor-related protein complex 5 beta subunit) (Beta5)AP5B1 PP1030Q2VPB77
APOC4-APOC2 readthrough (NMD candidate)APOC4-APOC2K7ER747
Aquaporin-7 (AQP-7) (Aquaglyceroporin-7) (Aquaporin adipose) (AQPap) (Aquaporin-7-like)AQP7 AQP7L AQP9O145207
ARF6 proteinARF6Q6FH177
Armadillo repeat-containing X-linked protein 3 (ARM protein lost in epithelial cancers on chromosome X 3) (Protein ALEX3)ARMCX3 ALEX3 BM-017 UNQ2517/PRO6007Q9UH627
Arp2/3 complex 34 kDa subunitARPC2 hCG_16304Q53R197
ATP-binding cassette sub-family F member 1 (Fragment)ABCF1H0YGW77
B box and SPRY domain-containing proteinBSPRYQ5W0U47
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)BCL10 CIPER CLAPO959997
Basement membrane-specific heparan sulfate proteoglycan core protein variant (Fragment)0Q59EG07
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)BCL2L1 BCL2L BCLXQ078177
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2BNIP2 NIP2Q129827
Beta-microseminoprotein (Immunoglobulin-binding factor) (IGBF) (PN44) (Prostate secreted seminal plasma protein) (Prostate secretory protein of 94 amino acids) (PSP-94) (PSP94) (Seminal plasma beta-inhibin)MSMB PRSPP081187
Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta)NAPB SNAPBQ9H1157
Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog)BLOC1S4 CNOQ9NUP17
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein)FHITP497897
BLOC-1-related complex subunit 7 (Diaskedin)BORCS7 C10orf32Q96B457
Blood group Rh(CE) polypeptide (Rh polypeptide 1) (RhPI) (Rh30A) (RhIXB) (Rhesus C/E antigens) (CD antigen CD240CE)RHCE RHC RHEP185777
Brain-specific serine protease 4 (BSSP-4) (EC 3.4.21.-) (Serine protease 22) (Serine protease 26) (Tryptase epsilon)PRSS22 BSSP4 PRSS26 SP001LA UNQ302/PRO343Q9GZN47
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)BRCA2 FACD FANCD1P515877
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)ARFGEF3 BIG3 C6orf92 KIAA1244Q5TH697
Bromodomain and WD repeat-containing protein 3BRWD3Q6RI457
Butyrophilin subfamily 3 member A3BTN3A3 BTF3O004787
C-1-tetrahydrofolate synthase, cytoplasmicMTHFD1F5H2F47
C-C chemokine receptor-like 2 (Chemokine receptor CCR11) (Chemokine receptor X) (Putative MCP-1 chemokine receptor)CCRL2 CCR11 CCR6 CKRX CRAM HCRO004217
C1GALT1-specific chaperone 1 (C38H2-like protein 1) (C38H2-L1) (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)C1GALT1C1 COSMC HSPC067 MSTP143 UNQ273/PRO310Q96EU77
Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)CDH16 UNQ695/PRO1340O753097
Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2)CADPS2 CAPS2 KIAA1591Q86UW77
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)PDE1CQ141237
Calmodulin-1 (Fragment)CALM1G3V3617
Calreticulin variant (Fragment)0Q53G717
CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein)CLIP2 CYLN2 KIAA0291 WBSCR3 WBSCR4 WSCR4Q9UDT67
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