EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT)CRAT CAT1P431557
Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)CSNK1D HCKIDP487307
Caspase-4 (CASP-4) (EC 3.4.22.57) (ICE and Ced-3 homolog 2) (ICH-2) (ICE(rel)-II) (Mih1) (Protease TX) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]CASP4 ICH2P496627
Catenin delta-1CTNND1C9JZR27
Cathepsin DCTSDF8WD967
Cathepsin D (Fragment)CTSDH7C1V07
CD59 glycoproteinCD59E9PR177
cDNA FLJ14168 fis, clone NT2RP2001440, highly similar to 14-3-3 protein gamma0B3KNB47
cDNA FLJ41981 fis, clone SMINT2011888, highly similar to Protein Tro alpha1 H,myeloma0Q6ZVX07
cDNA FLJ44920 fis, clone BRAMY3011501, highly similar to Heterogeneous nuclear ribonucleoprotein U0B3KX727
cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to Vinculin0B3KXA27
cDNA FLJ51818, highly similar to Phosphoglucomutase-1 (EC 5.4.2.2)0B4DFP17
cDNA FLJ52558, highly similar to Keratin, type I cytoskeletal 130B4DL177
cDNA FLJ52996, highly similar to Syntenin-10B4DQ937
cDNA FLJ53698, highly similar to Gelsolin0B7Z9927
cDNA FLJ54710, highly similar to Target of Myb protein 10B4DKQ57
cDNA FLJ56274, highly similar to Transketolase (EC 2.2.1.1)0B4E0227
cDNA FLJ56386, highly similar to Heat shock 70 kDa protein 1L0B4DI547
cDNA FLJ56766, highly similar to Protein disulfide-isomerase (EC5.3.4.1)0B4DJS07
cDNA FLJ57740, highly similar to Transforming protein RhoA0B4DKN97
cDNA FLJ58882, highly similar to 26S proteasome non-ATPase regulatory subunit 110B4DTS57
cDNA FLJ61636, highly similar to 40S ribosomal protein S90B7Z7327
cDNA FLJ75416, highly similar to Homo sapiens complement factor H (CFH), mRNA0A8K5T07
cDNA FLJ759500A8K0C27
cDNA FLJ76072, highly similar to Homo sapiens GIPC PDZ domain containing family, member 1 (GIPC1), transcript variant 1, mRNA0A8K2I77
cDNA FLJ77645, highly similar to Homo sapiens splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) (SFRS1), mRNA0A8K1L87
cDNA FLJ77762, highly similar to Homo sapiens cullin-associated and neddylation-dissociated 1 (CAND1), mRNA0A8K8U17
cDNA FLJ78413, highly similar to Homo sapiens albumin, mRNA0A8K9P07
cDNA FLJ78504, highly similar to Homo sapiens keratin 6A (KRT6A), mRNA0A8K2I07
cDNA FLJ78528, highly similar to Homo sapiens vacuolar protein sorting 4B (yeast) (VPS4B), mRNA0A8K4G77
cDNA FLJ786390A8K6Q67
cDNA FLJ90427 fis, clone NT2RP3000481, highly similar to Importin-70B3KQG67
cDNA, FLJ92490, highly similar to Homo sapiens RAB32, member RAS oncogene family (RAB32), mRNA0B2R5I87
cDNA, FLJ92973, highly similar to Homo sapiens villin 2 (ezrin) (VIL2), mRNA0B2R6J27
cDNA, FLJ93036, highly similar to Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenaseactivation protein, eta polypeptide (YWHAH), mRNA0B2R6N67
cDNA, FLJ93510, highly similar to Homo sapiens JTV1 gene (JTV1), mRNA0B2R7M37
cDNA, FLJ93777, highly similar to Homo sapiens prominin 2 (PROM2), mRNA0B2R8797
cDNA, FLJ94025, highly similar to Homo sapiens tripartite motif-containing 28 (TRIM28), mRNA0B2R8R57
cDNA, FLJ94267, highly similar to Homo sapiens glutathione S-transferase omega 1 (GSTO1), mRNA0B2R9837
cDNA, FLJ94440, highly similar to Homo sapiens chaperonin containing TCP1, subunit 6A (zeta 1)(CCT6A), mRNA0B2R9K87
cDNA, FLJ95508, highly similar to Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), mRNA0B2RBH27
cDNA, FLJ96587, highly similar to Homo sapiens SUMO-1 activating enzyme subunit 2 (UBA2), mRNA0B2RDF57
Choline transporter-like protein 2 (Fragment)SLC44A2K7EPV67
Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB)CHKB CHETK CHKLQ9Y2597
Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase)CHPF2 CHSY3 CSGLCAT KIAA1402 UNQ299/PRO339Q9P2E57
Choriogonadotropin subunit beta variant 1CGB1A6NKQ97
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)CBX8 PC3 RC1Q9HC527
Chromosome-associated kinesin KIF4B (Chromokinesin-B)KIF4BQ2VIQ37
Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1)CFAP45 CCDC19 NESG1Q9UL167
Clavesin-2 (Retinaldehyde-binding protein 1-like 2) (clathrin vesicle-associated Sec14 protein 2)CLVS2 C6orf212 C6orf213 RLBP1L2Q5SYC17
Coiled-coil domain-containing protein 51CCDC51Q96ER97
Coiled-coil domain-containing protein 88B (Brain leucine zipper domain-containing protein) (Gipie) (Hook-related protein 3) (HkRP3)CCDC88B BRLZA6NC987
Collagen alpha-1(XII) chain (Fragment)COL12A1H0Y4P77
Collagen alpha-1(XII) chain (Fragment)COL12A1H0Y9917
Collagen alpha-1(XIX) chain (Collagen alpha-1(Y) chain)COL19A1Q149937
Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin]COL4A3Q019557
Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)MMP13P454527
Complement C1q subcomponent subunit BC1QBD6R9347
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]C4A CO4 CPAMD2Q6P4R17
Complement decay-accelerating factor (Fragment)CD55H3BLV07
Complement factor I (Complement factor I, isoform CRA_b)CFI hCG_21044G3XAM27
COPG protein (Fragment)COPGQ8WUI67
Copine-1 (Fragment)CPNE1F2Z2V07
Copine-8CPNE8E7ENV77
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)CDKN2C CDKN6P427737
Cytidine 5'-monophosphate N-acetylneuraminic acid synthetase variant (Fragment)0Q53GF07
Cytochrome b-c1 complex subunit 10 (Complex III subunit 10) (Complex III subunit XI) (Ubiquinol-cytochrome c reductase complex 6.4 kDa protein)UQCR11 UQCRO149577
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1)COX7A2L COX7AR COX7RPO145487
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)CYTH3 ARNO3 GRP1 PSCD3O437397
Cytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1)NUBP1 NBP NBP1P533847
Cytovillin 2 (Fragment)VIL2Q9UJU17
Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)DMTN DMT EPB49Q084957
DENN domain-containing protein 4BDENND4B KIAA0476O750647
DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6)DEPTOR DEPDC6Q8TB457
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)DLG2Q157007
DNA damage-binding protein 1DDB1F5GY557
DNA dC->dU-editing enzyme APOBEC-3B (A3B) (EC 3.5.4.-) (Phorbolin-1-related protein) (Phorbolin-2/3)APOBEC3BQ9UH177
DNA helicase (EC 3.6.4.12)0B2R7C57
DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1)DMAP1 KIAA1425Q9NPF57
DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50)POLD2P490057
DNA-dependent protein kinase catalytic subunit (Fragment)PRKDCF5GX407
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA polymerase II subunit M) (Glutamate receptor-like protein 1A)POLR2M GRINL1AP0CAP27
DnaJ homolog subfamily B member 12DNAJB12Q9NXW27
Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 2) (Long NOX 2) (NADH/NADPH thyroid oxidase p138-tox) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (p138 thyroid oxidase)DUOX2 LNOX2 THOX2Q9NRD87
Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4O147337
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)RING1 RNF1Q065877
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)RNF2 BAP1 DING HIPI3 RING1BQ994967
E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) (RING-type E3 ubiquitin transferase RNF123)RNF123 KPC1 FP1477Q5XPI47
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)TRIM33 KIAA1113 RFG7 TIF1GQ9UPN97
E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II)UBR2 C6orf133 KIAA0349Q8IWV87
E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)UBR3 KIAA2024 ZNF650Q6ZT127
Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Dombrock blood group carrier molecule) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ribosyltransferase 4) (CD antigen CD297)ART4 DO DOK1Q930707
Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (EC 3.6.1.42) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5)ENTPD5 CD39L4 PCPHO753567
EEF1A protein (Fragment)EEF1AQ142227
eIF5 proteinEIF5Q6IBU07
Endophilin-B2SH3GLB2B7ZC397
Endoplasmic reticulum-Golgi intermediate compartment protein 2ERGIC2 ERV41 PTX1 CDA14Q96RQ17
Endothelin-converting enzyme 1 (cDNA FLJ59212, highly similar to Endothelin-converting enzyme 1 (EC 3.4.24.71))ECE1B4DKB27
Epidermal growth factor receptor kinase substrate 8-like protein 2 (Fragment)EPS8L2E9PLH17
ER membrane protein complex subunit 4 (Cell proliferation-inducing gene 17 protein) (Transmembrane protein 85)EMC4 TMEM85 HSPC184 PIG17Q5J8M37
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