EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Proteasome endopeptidase complex (EC 3.4.25.1)PSMA3G3V4X57
Proteasome subunit alpha type (EC 3.4.25.1)0Q5U0A07
Proteasome subunit alpha type-3PSMA3G3V3W47
Proteasome subunit beta type (EC 3.4.25.1)0B2RAQ97
Proteasome subunit beta type (EC 3.4.25.1)PSMB9 hCG_17510A2ACR17
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1)AATF CHE1 DED HSPC277Q9NY617
Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein)APCDD1 DRAPC1 FP7019Q8J0257
Protein arginine N-methyltransferase 1PRMT1E9PKG17
Protein arginine N-methyltransferase 5 (EC 2.1.1.-)0B2RDD77
Protein bassoon (Zinc finger protein 231)BSN KIAA0434 ZNF231Q9UPA57
Protein CMSS1 (Cms1 ribosomal small subunit homolog)CMSS1 C3orf26Q9BQ757
Protein cordon-bleuCOBL KIAA0633O751287
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)CCDC88C DAPLE KIAA1509Q9P2197
Protein FAM167AFAM167A C8orf13Q96KS97
Protein FAM186AFAM186AA6NE017
Protein FAM83FFAM83FQ8NEG47
Protein FAM83HFAM83HQ6ZRV27
Protein G6bG6B C6orf25O958667
Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4)GUCD1 C22orf13 LLN4Q96NT37
Protein Hook homolog 2 (h-hook2) (hHK2)HOOK2Q96ED97
Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta)PRKCH PKCL PRKCLP247237
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)PRKCZ PKC2Q055137
Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8)NDRG4 BDM1 KIAA1180Q9ULP07
Protein phosphatase inhibitor 2-like protein 3 (Protein phosphatase 1, regulatory subunit 2 pseudogene 3)PPP1R2P3Q6NXS17
Protein RMD5 homolog ARMND5AQ9H8717
Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA)SDAD1 NUC130Q9NVU77
Protein SOGA3SOGA3 C6orf174Q5TF217
Protein unc-93 homolog B1 (Unc-93B1) (hUNC93B1)UNC93B1 UNC93 UNC93BQ9H1C47
Protein virilizer homologKIAA1429 MSTP054Q69YN47
Protein Z-dependent protease inhibitor (Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 10, isoform CRA_a)SERPINA10 hCG_22331G3V2W17
Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 2) (TPST-2)TPST2O607047
Protocadherin alpha-C2 (PCDH-alpha-C2)PCDHAC2Q9Y5I47
Protocadherin-18PCDH18 KIAA1562Q9HCL07
Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1)SLC36A1 PAT1Q7Z2H87
Pulmonary surfactant-associated protein B (SP-B) (18 kDa pulmonary-surfactant protein) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe))SFTPB SFTP3P079887
Putative 60S ribosomal protein L13a protein RPL13AP3 (60S ribosomal protein L13a pseudogene 3)RPL13AP3Q6NVV17
Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10)SLC38A10 PP1744Q9HBR07
Putative tenascin-XA (TN-XA)TNXA XAQ164737
Putative trypsin-6 (EC 3.4.21.4) (Serine protease 3 pseudogene 2) (Trypsinogen C)PRSS3P2 T6 TRY6Q8NHM47
Putative uncharacterized protein DKFZp564A2282 (Fragment)DKFZp564A2282Q9NSM57
Putative uncharacterized protein DKFZp686G11190DKFZp686G11190Q6MZQ67
Putative uncharacterized protein DKFZp686L0869DKFZp686L0869Q7Z3U57
PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)PXKQ7Z7A47
Pyridoxal kinasePDXKF2Z2Y47
Rab GDP dissociation inhibitor0B4DLV77
Rab-like protein 3RABL3Q5HYI87
Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)RABGEF1 RABEX5Q9UJ417
Rab9 effector protein with kelch motifs (40 kDa Rab9 effector protein) (p40)RABEPK RAB9P40Q7Z6M17
Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20)RBSN ZFYVE20Q9H1K07
Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220)RALGAPA2 C20orf74 KIAA1272Q2PPJ77
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)RAP1GAP KIAA0474 RAP1GA1P477367
RAP1A, member of RAS oncogene family0Q5U0C37
RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI) (Cdc25-like protein) (hCDC25L) (F25B3.3 kinase-like protein)RASGRP2 CDC25L MCG7Q7LDG77
Ras-associating and dilute domain-containing proteinRADIL KIAA1849Q96JH87
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) (Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_b)RAC1 hCG_14926 tcag7.839A4D2P27
Ras-related GTP-binding protein D (Rag D) (RagD)RRAGDQ9NQL27
Ras-related protein Rab-28RAB28P511577
Ras-related protein Rab-9B (Rab-9-like protein) (Rab-9L)RAB9B RAB9LQ9NP907
Receptor of-activated protein C kinase 1 (Fragment)RACK1H0YAF87
Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X)UPF3B RENT3B UPF3XQ9BZI77
Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)RTN4R NOGOR UNQ330/PRO526Q9BZR67
Reticulon-4 receptor-like 1 (Nogo receptor-like 2) (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3)RTN4RL1 NGRH2 NGRL2Q86UN27
RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)RGMBQ6NW407
Rheumatoid factor RF-IP16 (Fragment)0A2J1P07
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)ARHGAP21 ARHGAP10 KIAA1424Q5T5U37
Rho GTPase-activating protein 27 (CIN85-associated multi-domain-containing Rho GTPase-activating protein 1) (Rho-type GTPase-activating protein 27) (SH3 domain-containing protein 20)ARHGAP27 CAMGAP1 SH3D20 PP905Q6ZUM47
Rho guanine nucleotide exchange factor 37ARHGEF37A1IGU57
Ribonuclease P protein subunit p29 (hPOP4) (EC 3.1.26.5)POP4 RPP29O957077
Ribonuclease P protein subunit p40 (RNaseP protein p40) (EC 3.1.26.5) (RNase P subunit 1)RPP40 RNASEP1O758187
Ribosomal protein 63, mitochondrial (hMRP63) (Mitochondrial large ribosomal subunit protein mL63) (Mitochondrial ribosomal protein 63) (Mitochondrial ribosomal protein L57)MRPL57 MRP63Q9BQC67
Ribosomal protein L11, isoform CRA_b (cDNA, FLJ92077, Homo sapiens ribosomal protein L11 (RPL11), mRNA)RPL11 hCG_1739238Q5VVD07
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)RPS6KB1 STK14AP234437
RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)RNF7 RBX2 ROC2 SAGQ9UBF67
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)RBFOX2 FOX2 HRNBP2 RBM9 RTAO432517
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16)SSU72 HSPC182 PNAS-120Q9NP777
RNA polymerase-associated protein RTF1 homologRTF1 KIAA0252Q925417
RNA-binding motif protein, X-linked-like-2 (Testis-specific heterogeneous nuclear ribonucleoprotein G-T) (hnRNP G-T)RBMXL2 HNRNPGTO755267
RNA-binding protein 34 (RNA-binding motif protein 34)RBM34 KIAA0117P426967
RNA-binding protein 42 (RNA-binding motif protein 42)RBM42Q9BTD87
RPL13A protein (Fragment)RPL13AQ9BSQ67
RPL21 protein (Ribosomal protein L21) (Ribosomal protein L21, isoform CRA_a) (cDNA, FLJ92056, Homo sapiens ribosomal protein L21 (RPL21), mRNA)RPL21 hCG_2020044Q6IAX27
RPS10-NUDT3 readthrough (Fragment)RPS10-NUDT3S4R4357
S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]AMD1 AMDP177077
S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin)SAGP105237
S100 calcium binding protein A10 (Annexin II ligand, calpactin I, light polypeptide (P11)), isoform CRA_b (Fragment)S100A10 hCG_16920D3DV267
SCARB1 protein (Scavenger receptor class B member 1)SCARB1B7ZKQ97
SEC14-like protein 1SEC14L1 SEC14LQ925037
Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE)SFRP4 FRPHEQ6FHJ77
Secreted Ly-6/uPAR-related protein 1 (SLURP-1) (ARS component B) (ARS(component B)-81/S) (Anti-neoplastic urinary protein) (ANUP)SLURP1 ARSP550007
Septin-8SEPT8A6NFQ97
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)HTRA2 OMI PRSS25O434647
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)STRAP MAWD UNRIPB4DNJ67
Serine/arginine-rich-splicing factor 1 (Splicing factor, arginine/serine-rich 1 (Splicing factor 2, alternate splicing factor), isoform CRA_g)SRSF1 SFRS1 hCG_1774411J3KTL27
Serine/threonine-protein kinase 24 (cDNA FLJ61159, highly similar to Serine/threonine-protein kinase 24 (EC 2.7.11.1))STK24B4DR807
Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)CDC42BPG DMPK2Q6DT377
Serpin B13 (HaCaT UV-repressible serpin) (Hurpin) (Headpin) (Peptidase inhibitor 13) (PI-13) (Proteinase inhibitor 13)SERPINB13 PI13Q9UIV87
SFPQ protein (Fragment)SFPQQ9BSV47
Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328)SIGLEC7 AIRM1Q9Y2867
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)SLAMF1 SLAMQ132917
Single chain Fv (Fragment)0Q9HCC17
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