EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase II) (XT-II) (XylT-II)XYLT2 XT2 UNQ3058/PRO9878Q9H1B57
Y-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog)YBX2 CSDA3 MSY2Q9Y2T77
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)YTHDC1 KIAA1966 YT521Q96MU77
Zinc finger CCCH domain-containing protein 7AZC3H7A ZC3H7 ZC3HDC7 HSPC055Q8IWR07
Zinc finger protein 318 (Endocrine regulatory protein)ZNF318 HRIHFB2436Q5VUA47
Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein)ZNF330 NOA36Q9Y3S27
Zinc finger SWIM domain-containing protein 8ZSWIM8 KIAA0913A7E2V47
Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4)SLC39A4 ZIP4Q6P5W57
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2)PLCH2 KIAA0450 PLCL4O750386
14-3-3 protein beta/alpha (Fragment)YWHABQ4VY206
2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L)RNASEL RNS4Q058236
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)BCKDHAP126946
26S protease regulatory subunit 6A (Fragment)PSMC3E9PMD86
26S proteasome non-ATPase regulatory subunit 13 (Fragment)PSMD13E9PL386
26S proteasome non-ATPase regulatory subunit 2 (Fragment)PSMD2H7C2Q36
26S proteasome non-ATPase regulatory subunit 8PSMD8R4GMR56
26S proteasome non-ATPase regulatory subunit 8PSMD8K7EJC16
3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO)ERI1 3'EXO THEX1Q8IV486
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)KDSR FVT1 SDR35C1Q061366
39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3) (Mitochondrial large ribosomal subunit protein uL3m)MRPL3 MRL3 RPML3P090016
39S ribosomal protein L39, mitochondrial (Fragment)MRPL39C9JG876
40S ribosomal protein S16 (RPS16 protein)RPS16Q6IPX46
40S ribosomal protein S3RPS3E9PSF46
40S ribosomal protein S3 (Fragment)RPS3E9PK826
5'-nucleotidase (Fragment)NT5EH0Y7R76
60S acidic ribosomal protein P0RPLP0F8W1K86
60S ribosomal protein L18aRPL18AM0R1176
60S ribosomal protein L24RPL24C9JXB86
60S ribosomal protein L28RPL28H0YKD86
60S ribosomal protein L32RPL32F8W7276
60S ribosomal protein L37 (G1.16) (Large ribosomal subunit protein eL37)RPL37P619276
60S ribosomal protein L5 (Fragment)RPL5Q5T7N06
A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme)ADAMTS3 KIAA0366O150726
A-kinase anchor protein 4 (AKAP-4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI) (Protein kinase A-anchoring protein 4) (PRKA4)AKAP4 AKAP82Q5JQC96
A-kinase anchor protein 8-like (AKAP8-like protein) (Helicase A-binding protein 95) (HAP95) (Homologous to AKAP95 protein) (HA95) (Neighbor of A-kinase-anchoring protein 95) (Neighbor of AKAP95)AKAP8L NAKAP NAKAP95 HRIHFB2018Q9ULX66
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)ACAT2 ACTLB7Z2336
Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Fragment)DLATH0YDD46
Acid phosphatase 1 isoform c variant (Fragment)0Q59EH36
Actin-related protein 2/3 complex subunit 4ARPC4-TTLL3F8WCF66
Acyl-CoA-binding domain-containing protein 6ACBD6Q9BR616
Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128)ACOT2 PTE2 PTE2AP497536
Acylamino-acid-releasing enzymeAPEHC9JIF96
Acylamino-acid-releasing enzymeAPEHF8WEH56
ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2)ADAMTSL3 KIAA1233P829876
Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5)AK5Q9Y6K86
Adhesion G-protein coupled receptor G4 (G-protein coupled receptor 112)ADGRG4 GPR112Q8IZF66
ADP-ribosylation factor 5 (ADP-ribosylation factor 5, isoform CRA_a) (cDNA, FLJ92389, Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA)ARF5 hCG_32325 tcag7.6A4D0Z36
Albumin (Fragment)0F6KPG56
Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha)ADH1A ADH1P073276
Aldo-keto reductase family 1 member C3 (Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_a)AKR1C3 hCG_19343S4R3Z26
Alpha- and gamma-adaptin-binding protein p34AAGABQ6PD746
Alpha-(1,3)-fucosyltransferase 6 (EC 2.4.1.65) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase)FUT6 FCT3AP519936
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)MGAT4B UNQ906/PRO1927Q9UQ536
Alpha-actinin-1 (Fragment)ACTN1G3V2E86
Alpha-actinin-1 (Fragment)ACTN1G3V3806
Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)CTNNAL1Q9UBT76
Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168); Alpha-crystallin A(1-162)]CRYAA CRYA1 HSPB4P024896
Alpha-N-acetylglucosaminidase (Fragment)NAGLUK7ENX56
Alpha-tectorinTECTAO754436
Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)ALS2 ALS2CR6 KIAA1563Q96Q426
Amino acid transporterSLC1A5Q71UA66
Ankyrin repeat and SOCS box protein 15 (ASB-15)ASB15Q8WXK16
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)SOWAHC ANKRD57 C2orf26Q53LP36
AnnexinANXA11 hCG_22492Q5T0G86
Annexin0B4DT776
Annexin A5ANXA5D6RCN36
Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B-48 receptor) (Apolipoprotein B48 receptor) (apoB-48R)APOBR APOB48RQ0VD836
Apolipoprotein E (Fragment)APOEE9PEV46
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)AGAP1 CENTG2 KIAA1099Q9UPQ36
Armadillo repeat-containing protein 1ARMC1 ARCPQ9NVT96
Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2)ASPA ACY2 ASPP453816
AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)ARID4B BRCAA1 RBBP1L1 RBP1L1 SAP180Q4LE396
AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)ARID5B DESRT MRF2Q148656
ATP synthase protein 8 (A6L) (F-ATPase subunit 8)MT-ATP8 ATP8 ATPASE8 MTATP8P039286
ATP synthase subunit beta (EC 3.6.3.14) (Fragment)ATP5BH0YH816
ATP-binding cassette sub-family A member 7 (ABCA-SSN) (Autoantigen SS-N) (Macrophage ABC transporter)ABCA7Q8IZY26
ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)ABCB7 ABC7O750276
ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69)ABCD4 PXMP1LO146786
ATR-interacting protein (ATM and Rad3-related-interacting protein)ATRIP AGS1Q8WXE16
BAH and coiled-coil domain-containing protein 1 (Bromo adjacent homology domain-containing protein 2) (BAH domain-containing protein 2)BAHCC1 BAHD2 KIAA1447Q9P2816
Band 4.1-like protein 4A (Protein NBL4)EPB41L4A EPB41L4Q9HCS56
Basal cell adhesion moleculeBCAMA0A087WXM86
Basigin (Fragment)BSGR4GN836
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3BNIP3 NIP3Q129836
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]BECN1 GT197Q144576
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)BET1L GS15Q9NYM96
Beta-globin (Mutant beta-globin) (Fragment)HBBQ9GZL96
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L0Y96
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L2M46
Breast carcinoma-amplified sequence 3 (GAOB1)BCAS3Q9H6U66
Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7)BCAN BEHAB CSPG7 UNQ2525/PRO6018Q96GW76
Bridging integrator 3BIN3Q9NQY06
BUD13 homologBUD13Q9BRD06
Butyrophilin subfamily 2 member A2BTN2A2 BT2.2 BTF2Q8WVV56
Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)CELSR3 CDHF11 EGFL1 FMI1 KIAA0812 MEGF2Q9NYQ76
Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel family member 1) (hCLCA1) (Calcium-activated chloride channel protein 1) (CaCC-1) (hCaCC-1)CLCA1 CACC1A8K7I46
Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)CADPS CAPS CAPS1 KIAA1121Q9ULU86
CALM1 protein (Calmodulin 2 (Phosphorylase kinase, delta), isoform CRA_a) (Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a) (Calmodulin-1) (Calmodulin-3) (LP7057 protein)CALM1 CALM2 CALM3 hCG_17033 hCG_20313Q96HY36
CalmodulinCALM2F8WBR56
Calmodulin (Fragment)CALM2H0Y7A76
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