EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_d (Calmodulin-1) (Calmodulin-2) (Calmodulin-3)CALM1 CALM2 CALM3 hCG_20313M0QZ526
Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2)CAPNS2Q96L466
CalponinCNN2B4DDF46
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)CNN1P519116
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)PDE10AQ9Y2336
cAMP-regulated phosphoprotein 19 (ARPP-19)ARPP19P562116
Capping protein (Actin filament) muscle Z-line, alpha 2 (Capping protein (Actin filament) muscle Z-line, alpha 2, isoform CRA_b) (cDNA, FLJ95684, Homo sapiens capping protein (actin filament) muscle Z-line, alpha2 (CAPZA2), mRNA)CAPZA2 hCG_37884 tcag7.31A4D0V46
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)CTDSP2 NIF2 OS4 SCP2O145956
Carboxypeptidase A1 (EC 3.4.17.1)CPA1 CPAP150856
Cartilage oligomeric matrix protein (Cartilage oligomeric matrix protein, isoform CRA_b)COMP hCG_37043G3XAP66
Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]CASP2 ICH1 NEDD2P425756
Cation-transporting ATPase 13A2 (EC 3.6.3.-)ATP13A2 PARK9Q9NQ116
CCT7 proteinCCT7Q6IBT36
CD44 antigen (Fragment)CD44H0Y2P06
CD81 antigen (Fragment)CD81E9PM316
cDNA FLJ12434 fis, clone NT2RM1000037, highly similar to Homo sapiens KIAA0690 protein0B3KMR56
cDNA FLJ14048 fis, clone HEMBA1006650, weakly similar to ARP2/3 COMPLEX 20 KD SUBUNIT0Q9H7Z56
cDNA FLJ20193 fis, clone COLF07950Q9NXK56
cDNA FLJ35079 fis, clone PLACE6005283, highly similar to Lysosome-associated membrane glycoprotein 10B3KRY36
cDNA FLJ50805, highly similar to Erythrocyte membrane protein band 4.20B7Z4C36
cDNA FLJ51535, highly similar to Phosphatidylethanolamine-binding protein 10B4DRT46
cDNA FLJ531100B7Z7D56
cDNA FLJ53202, highly similar to Exportin-20B4DUC56
cDNA FLJ54141, highly similar to Ezrin0B7Z5V26
cDNA FLJ54170, highly similar to Cytosolic nonspecific dipeptidase0B4DV286
cDNA FLJ54373, highly similar to 60 kDa heat shock protein, mitochondrial0B7Z5976
cDNA FLJ54582, highly similar to Ubiquitin-activating enzyme E10B4DDE46
cDNA FLJ54657, highly similar to Keratin, type II cytoskeletal 6A0B4DRU66
cDNA FLJ54963, highly similar to Tubulointerstitial nephritis antigen-like0B4DNS56
cDNA FLJ56068, highly similar to DNA damage-binding protein 10B7Z2A16
cDNA FLJ58780, highly similar to Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2B, mRNA0B4E2S76
cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier0B4DLN16
cDNA FLJ60317, highly similar to Aminoacylase-1 (EC 3.5.1.14)0B4DNW06
cDNA FLJ61192, highly similar to Erythrocyte band 7 integral membrane protein0B4DZK86
cDNA FLJ75876, highly similar to Homo sapiens solute carrier family 38, member 2 (SLC38A2), mRNA0A8K6H96
cDNA FLJ76904, highly similar to Homo sapiens methionine adenosyltransferase II, beta (MAT2B), transcript variant 2, mRNA0A8K7A46
cDNA FLJ77590, highly similar to Homo sapiens leucine rich repeat containing 1, mRNA0A8K8836
cDNA FLJ78655, highly similar to Homo sapiens exportin 5 (XPO5), mRNA0A8K5Y76
cDNA FLJ90170 fis, clone MAMMA1000370, highly similar to Ig alpha-1 chain C region0Q8NCL66
cDNA, FLJ92862, highly similar to Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 1 (SLC16A1), mRNA0B2R6A56
cDNA, FLJ93375, highly similar to Homo sapiens ZW10, kinetochore associated, homolog (Drosophila) (ZW10), mRNA0B2R7C26
cDNA, FLJ93598, highly similar to Homo sapiens capping protein (actin filament) muscle Z-line, beta (CAPZB), mRNA0B2R7T86
cDNA, FLJ94534, highly similar to Homo sapiens capping protein (actin filament), gelsolin-like(CAPG), mRNA0B2R9S46
Cell adhesion molecule 3 (Brain immunoglobulin receptor) (Immunoglobulin superfamily member 4B) (IgSF4B) (Nectin-like protein 1) (NECL-1) (Synaptic cell adhesion molecule 3) (SynCAM3) (TSLC1-like protein 1) (TSLL1)CADM3 IGSF4B NECL1 SYNCAM3 TSLL1 UNQ225/PRO258Q8N1266
Centlein (Centrosomal protein)CNTLN C9orf101 C9orf39Q9NXG06
Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110)CCP110 CEP110 CP110 KIAA0419O433036
Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)CNTRL CEP1 CEP110Q7Z7A16
Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)CENPJ CPAP LAP LIP1Q9HC776
Chondroadherin (Cartilage leucine-rich protein)CHAD SLRR4AO153356
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1)CSGALNACT1 CHGN GALNACT1 UNQ656/PRO1287Q8TDX66
Chondroitin sulfate proteoglycan 5 (Acidic leucine-rich EGF-like domain-containing brain protein) (Neuroglycan C)CSPG5 CALEB NGCO951966
Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3)CHSY3 CHSY2 CSS3Q70JA76
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)SLC18A1 VAT1 VMAT1P542196
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)CHD7 KIAA1416Q9P2D16
Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)CHD9 KIAA0308 KISH2 PRIC320 AD-013 x0008Q3L8U16
Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)CHAMP1 C13orf8 CAMP CHAMP KIAA1802 ZNF828Q96JM36
Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40)CFAP46 C10orf123 C10orf124 C10orf92 C10orf93 TTC40Q8IYW26
Citrate synthaseCSB4DJV26
Claudin-15CLDN15P567466
Coactosin-like proteinCOTL1H3BT586
Coiled-coil domain-containing protein 134CCDC134Q9H6E46
Coiled-coil domain-containing protein 168CCDC168 C13orf40Q8NDH26
Coiled-coil domain-containing protein 171CCDC171 C9orf93Q6TFL36
Coiled-coil domain-containing protein 57CCDC57Q2TAC26
Coiled-coil domain-containing protein 9CCDC9Q9Y3X06
COMM domain-containing protein 8COMMD8 MDS022Q9NX086
Complement C1r subcomponentC1RF5H2D06
Complement component 8, beta polypeptide, isoform CRA_b (cDNA FLJ59731, highly similar to Complement component C8 beta chain)C8B hCG_23458B7Z5506
Complement component C8 beta chainC8BF5GY806
Contactin-5 (Neural recognition molecule NB-2) (hNB-2)CNTN5O947796
Contactin-associated protein-like 4 (Cell recognition molecule Caspr4)CNTNAP4 CASPR4 KIAA1763Q9C0A06
COP9 signalosome complex subunit 3COPS3H7C3P96
COP9 signalosome complex subunit 8COPS8E9PGT66
Copine-7 (Copine VII)CPNE7Q9UBL66
Copine-9 (Copine IX)CPNE9Q8IYJ16
Cornifin-A (19 kDa pancornulin) (SPRK) (Small proline-rich protein IA) (SPR-IA)SPRR1AP353216
Coronin-2A (IR10) (WD repeat-containing protein 2)CORO2A IR10 WDR2Q928286
Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)HSD11B1 HSD11 HSD11L SDR26C1P288456
Cryocrystalglobulin CC1 kappa light chain variable region (Fragment)0B1N7B86
CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (hNAPOR) (RNA-binding protein BRUNOL-3)CELF2 BRUNOL3 CUGBP2 ETR3 NAPORO953196
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)MB21D1 C6orf150Q8N8846
Cyclic nucleotide-binding domain-containing protein 2CNBD2 C20orf152Q96M206
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)CKS2P335526
Cyclin-KCCNK CPR4O759096
Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)COX6A1 COX6ALP120746
Cytoplasmic tRNA 2-thiolation protein 2 (Cytosolic thiouridylase subunit 2)CTU2 C16orf84 NCS2Q2VPK56
D-dopachrome decarboxylase-like protein (EC 4.1.1.-) (D-dopachrome tautomerase-like protein)DDTLA6NHG46
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)DCAF11 WDR23 GL014 PRO2389Q8TEB16
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)DCAF8 H326 WDR42AQ5TAQ96
Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)TFB2M NS5ATP5Q9H5Q46
Dimethylarginine dimethylaminohydrolase 1, isoform CRA_b (Epididymis secretory protein Li 16) (cDNA, FLJ92778, Homo sapiens dimethylarginine dimethylaminohydrolase 1 (DDAH1), mRNA)DDAH1 HEL-S-16 hCG_2040048B1AKK26
Dipeptidyl aminopeptidase-like protein 6 (DPPX) (Dipeptidyl aminopeptidase-related protein) (Dipeptidyl peptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl peptidase VI) (DPP VI)DPP6P426586
Disabled homolog 2-interacting protein (DAB2 interaction protein) (DAB2-interacting protein) (ASK-interacting protein 1) (AIP-1) (DOC-2/DAB-2 interactive protein)DAB2IP AF9Q34 AIP1 KIAA1743Q5VWQ86
Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Sperm maturation-related glycoprotein GP-83)ADAM7 GP83Q9H2U96
DNA helicase (EC 3.6.4.12)0B3KXZ46
DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4)XRCC4Q134266
DNA replication complex GINS protein PSF2 (GINS complex subunit 2)GINS2 PSF2 CGI-122 DC5 HSPC037Q9Y2486
DNA-directed RNA polymerase I subunit RPA43 (Twist neighbor protein)TWISTNBQ3B7266
DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide)POLR3E KIAA1452Q9NVU06
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)POLRMTO004116
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