EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1RPN1Q6IBR06
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Fragment)0Q96HX36
DPYSL3 proteinDPYSL3Q6DEN26
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11A)PDE11AQ9HCR96
Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity tyrosine phosphatase YVH1)DUSP12Q9UNI66
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)DYRK2Q926306
Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)DNAH12 DHC3 DLP12 DNAH12L DNAH7L DNAHC3 DNHD2 HDHC3 HL19Q6ZR086
Dynein heavy chain 17, axonemal (Axonemal beta dynein heavy chain 17) (Axonemal dynein heavy chain-like protein 1) (Ciliary dynein heavy chain 17) (Ciliary dynein heavy chain-like protein 1) (Dynein light chain 2, axonemal)DNAH17 DNAHL1 DNEL2Q9UFH26
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)SH3RF1 KIAA1494 POSH RNF142 SH3MD2Q7Z6J06
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)TRAF7 RFWD1 RNF119Q6Q0C06
Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2)ENTPD6 CD39L2 IL6ST2O753546
Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)EGLN1 C1orf12 PNAS-118 PNAS-137Q9GZT96
ELAV-like protein 1 (Hu-antigen R) (HuR)ELAVL1 HURB4DVB86
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)ETFDHQ161346
Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein)ELP5 C17orf81 DERP6 HSPC002 MSTP071Q8TE026
Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103)ELP6 ATP1 C3orf75 TMEM103Q0PNE26
EMILIN-3 (EMILIN-5) (Elastin microfibril interface-located protein 3) (Elastin microfibril interfacer 3) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5)EMILIN3 C20orf130 EMILIN5Q9NT226
Eosinophil cationic protein (ECP) (EC 3.1.27.-) (Ribonuclease 3) (RNase 3)RNASE3 ECP RNS3P127246
EPH receptor B3, isoform CRA_aEPHB3 hCG_16839D3DNT96
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)EPHB4 HTK MYK1 TYRO11B5A9726
Epidermal growth factor receptor kinase substrate 8EPS8F5H0R86
Epidermal growth factor receptor kinase substrate 8 (Fragment)EPS8H0YFG16
Epidermal growth factor receptor kinase substrate 8-like protein 1 (cDNA FLJ60287, highly similar to Epidermal growth factor receptor kinase substrate 8-like protein 1)EPS8L1B4DKV76
Epidermal growth factor receptor kinase substrate 8-like protein 2 (Fragment)EPS8L2H0YD626
Epidermal growth factor receptor substrate 15EPS15B1AUU86
Epithelial cell adhesion moleculeEPCAMB5MCA46
Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)SLC29A1 ENT1B3KQV76
Erlin-2 (Fragment)ERLIN2E5RHW46
Erythroid membrane-associated protein (hERMAP) (Radin blood group antigen) (Scianna blood group antigen)ERMAP RD SCQ96PL56
Estrogen sulfotransferase (EC 2.8.2.4) (EST-1) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring)SULT1E1 STEP498886
Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, isoform CRA_a (Full-length cDNA clone CS0DL010YH08 of B cells (Ramos cell line) of Homo sapiens (human)) (cDNA, FLJ92791, Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1), mRNA)EIF2S1 hCG_21909Q53XC06
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta)EIF3A EIF3S10Q24JU46
Eukaryotic translation initiation factor 3 subunit E (Fragment)EIF3EE5RHS56
Eukaryotic translation initiation factor 4 gamma 1EIF4G1E7EUU46
EzrinEZRQ6NUR76
FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)FOXRED2 ERFADQ8IWF26
Fas apoptotic inhibitory molecule 1FAIM FAIM1Q9NVQ46
Fatty acid-binding protein, liverFABP1A8MW496
Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT)FLVCR2 C14orf58Q9UPI36
Fermitin family homolog 2 (Fragment)FERMT2H0YJ346
Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2)FRRS1 SDFR2 SDR2Q6ZNA56
Fibulin-10Q8NBH66
Filamin-B (Fragment)FLNBH7C5L46
Flotillin 1 variant (Fragment)0Q53HQ06
FLYWCH family member 2FLYWCH2Q96CP26
FocadhesinFOCAD KIAA1797Q5VW366
Formin-like protein 3FMNL3F8W1F56
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)FHL3 SLIM2Q136436
Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)FHB1ANK76
Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)FURIN FUR PACE PCSK3P099586
FXYD domain-containing ion transport regulator 7FXYD7P585496
G patch domain and KOW motifs-containing protein (G patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54)GPKOW GPATC5 GPATCH5 T54Q929176
G-protein coupled receptor 176 (HB-954)GPR176Q144396
Galectin-10 (Gal-10) (Charcot-Leyden crystal protein) (CLC) (Eosinophil lysophospholipase) (Lysolecithin acylhydrolase)CLC LGALS10 LGALS10AQ053156
Galectin-3-binding protein (Lectin galactoside-binding soluble 3 binding protein isoform 2)LGALS3BPK7EJD36
Gap junction beta-2 protein (Connexin-26) (Cx26)GJB2P290336
GDP-L-fucose synthase (Fragment)TSTA3E9PKL96
Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase)MCM3AP GANP KIAA0572 MAP80O603186
Globin B1 (Hemoglobin, gamma A)HBG1 GLNB1D9YZU86
Globin B2 (Hemoglobin, gamma G)HBG2 GLNB2D9YZU96
Glucocorticoid-induced transcript 1 proteinGLCCI1Q86VQ16
Glucosamine 6-phosphate N-acetyltransferase (Fragment)GNPNAT1G3V4W46
Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (Fragment)G6PDE7EUI86
Glucose-6-phosphate isomerase (EC 5.3.1.9)0B4DE366
Glucose-6-phosphate isomerase (EC 5.3.1.9)GPIK7EQ486
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)GRIN2B NMDAR2BQ132246
Glutathione peroxidaseGPX1A0A087WUQ66
Glutathione S-transferase (EC 2.5.1.18)GSTM2F6XZQ76
Glutathione S-transferase C-terminal domain-containing proteinGSTCDQ8NEC76
Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3)0A8K1Z26
Glycoprotein integral membrane protein 1GINM1 C6orf72 UNQ710/PRO1361Q9NU536
Golgi pH regulator B (Protein GPR89B)GPR89B GPHRB GPR89C HSPC201P0CG086
Golgin subfamily A member 5 (Cell proliferation-inducing gene 31 protein) (Golgin-84) (Protein Ret-II) (RET-fused gene 5 protein)GOLGA5 RETII RFG5 PIG31Q8TBA66
GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)PIGK GPI8Q926436
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)GDF11 BMP11O953906
GTP-binding nuclear protein RanRANB4DV516
GTP-binding protein RAD (RAD1) (Ras associated with diabetes)RRAD RADP550426
GTP-binding protein RhebRHEBC9J9316
Guanine nucleotide exchange factor VAV3 (VAV-3)VAV3Q9UKW46
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Fragment)GNB1B1AKQ86
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)GNB1Q1RMY86
Guanine nucleotide-binding protein G(k) subunit alpha (G(i) alpha-3)GNAI3Q5TZX16
Guanine nucleotide-binding protein G, alpha subunit variant (Fragment)0Q59FM56
Guanine nucleotide-binding protein-like 3-like proteinGNL3LQ9NVN86
Guanylate cyclase soluble subunit alpha-3 (GCS-alpha-3) (EC 4.6.1.2) (GCS-alpha-1) (Soluble guanylate cyclase large subunit)GUCY1A3 GUC1A3 GUCSA3 GUCY1A1Q021086
Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)GUCY1B3 GUC1B3 GUCSB3 GUCY1B1Q021536
Guanylate-binding protein 6 (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)GBP6Q6ZN666
HAUS augmin-like complex subunit 3HAUS3 C4orf15Q68CZ66
HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48)HAUS8 HICE1Q9BT256
Heat shock 70 kDa protein 1-like (Heat shock 70kDa protein 1-like variant) (Fragment)HSPA1LQ53FA36
Heat shock 70kDa protein 6 (HSP70B') variant (Fragment)0Q53FC76
Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13)HSBP1 HSF1BPO755066
Heat shock protein 75 kDa, mitochondrial (TNF receptor-associated protein 1, isoform CRA_b)TRAP1 hCG_16634I3L0K76
Heat shock protein HSP 90-alpha (Fragment)HSP90AA1G3V2J86
Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)HLTF HIP116A RNF80 SMARCA3 SNF2L3 ZBU1Q145276
Hemoglobin subunit gamma-2HBG2E9PBW46
Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1)HS3ST1 3OST 3OST1O147926
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B)HS3ST3B1 3OST3B1 HS3ST3BQ9Y6626
Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)HGSNAT TMEM76Q68CP46
Hepatitis A virus cellular receptor 1 (HAVcr-1) (Kidney injury molecule 1) (KIM-1) (T-cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T-cell immunoglobulin mucin receptor 1) (TIM) (TIM-1) (T-cell membrane protein 1)HAVCR1 KIM1 TIM1 TIMD1Q96D426
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