EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dipeptidyl peptidase 1 (Fragment)CTSCH0YCY85
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (DIPP-3-beta) (DIPP3-beta) (hDIPP3beta) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 11) (Nudix motif 11) (hAps1)NUDT11 APS1 DIPP3BQ96G615
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)DLG5 KIAA0583 PDLGQ8TDM65
DNA helicase (EC 3.6.4.12)MCM5 hCG_41525B1AHB15
DNA helicase (EC 3.6.4.12) (Fragment)MCM2H0Y8E65
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)POLA2Q141815
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)POLR3D BN51 BN51TP054235
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)POLR3FQ9H1D95
Dolichol-phosphate mannosyltransferase subunit 1 (Fragment)DPM1H0Y3685
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Fragment)0Q53G025
Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog)ALG5 HSPC149Q9Y6735
Dopamine receptor interacting protein 4DRIP4Q4W4Y15
Doublecortin domain-containing protein 2 (Protein RU2S)DCDC2 KIAA1154 RU2Q9UHG05
Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)DSTYK KIAA0472 RIP5 RIPK5 SGK496 HDCMD38PQ6XUX35
Dynactin subunit 1 (Putative uncharacterized protein DKFZp686E0752)DKFZp686E0752 DCTN1Q6AWB15
Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2)DNAH7 KIAA0944Q8WXX05
Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2)DYNLRB2 DNCL2B DNLC2B ROBLD2Q8TF095
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)CBX4O002575
E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog)NSMCE2 C8orf36 MMS21Q96MF75
E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)RNF130Q86XS85
E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598)ZNF598Q86UK75
Echinoderm microtubule-associated protein-like 5 (EMAP-5)EML5Q05BV35
Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5)ENTPD8 UNQ2492/PRO5779Q5MY955
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase)ENPP7 UNQ3077/PRO9912Q6UWV65
EEF1A lysine methyltransferase 1 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2) (Protein-lysine N-methyltransferase N6AMT2)EEF1AKMT1 N6AMT2Q8WVE05
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A)CRACR2A EFCAB4BQ9BSW25
EKC/KEOPS complex subunit GON7GON7 C14orf142Q9BXV95
ELM2 and SANT domain-containing protein 1 (MIDEAS)ELMSAN1 C14orf117 C14orf43Q6PJG25
Elongation factor 1-alpha (Fragment)0Q53G855
Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein)ELP4 C11orf19 PAXNEBQ96EB15
Emerin (Emerin (Emery-Dreifuss muscular dystrophy), isoform CRA_b)EMD hCG_41343Q5HY575
Endogenous retrovirus group K member 19 Gag polyprotein (HERV-K(C19) Gag protein) (HERV-K_19q11 provirus ancestral Gag polyprotein) (Gag polyprotein)ERVK-19Q9YNA85
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)SH3GL3 CNSA3 SH3D2CQ999635
Endothelin-1 receptor (Endothelin A receptor) (ET-A) (ETA-R) (hET-AR)EDNRA ETA ETRAP251015
Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)EDC3 LSM16 YJDC YJEFN2 PP844Q96F865
Epidermal growth factor receptor kinase substrate 8EPS8B4DX665
Epidermal growth factor receptor kinase substrate 8-like protein 2 (Fragment)EPS8L2E9PN685
Epididymis luminal protein 76HEL-76V9HW215
Epididymis secretory protein Li 34 (Phosphatidylethanolamine binding protein 1, isoform CRA_a) (Phosphatidylethanolamine-binding protein 1)PEBP1 HEL-S-34 hCG_2016249D9IAI15
Epiplakin (450 kDa epidermal antigen)EPPK1 EPIPLQ9NSU95
ERC protein 2ERC2 KIAA0378O150835
ESF1 homolog (ABT1-associated protein)ESF1 ABTAP C20orf6 HDCMC28PQ9H5015
Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein)ESPN DFNB36 LP2654B1AK535
Eukaryotic initiation factor 4A-I (Fragment)EIF4A1J3KTN05
Eukaryotic peptide chain release factor subunit 1 (cDNA FLJ56175, highly similar to Eukaryotic peptide chain release factor subunit1)ETF1B7Z7P85
Eukaryotic translation initiation factor 2 subunit 1 (Fragment)EIF2S1H0YJS45
Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF-2-gamma X) (eIF-2gX)EIF2S3 EIF2GA8K2Y25
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)EIF3C EIF3S8H3BRV05
Eukaryotic translation initiation factor 3 subunit G (Fragment)EIF3GK7EL205
Eukaryotic translation initiation factor 4 gamma 2EIF4G2H0Y3P25
Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1)EIF4ENIF1Q9NRA85
Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)SLC1A2 EAAT2 GLT1P430045
Exocyst complex component 3-like protein 4EXOC3L4 C14orf73Q17RC75
F-actin-capping protein subunit beta (cDNA FLJ43095 fis, clone CORDB2000541, highly similar to F-actin capping protein subunit beta)CAPZBB1AK855
F-box only protein 15FBXO15 FBX15Q8NCQ55
F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8)FBXL8 FBL8Q96CD05
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)FDPS FPS KIAA1293E9PCI95
FDFT1 protein (Farnesyl-diphosphate farnesyltransferase 1) (Farnesyl-diphosphate farnesyltransferase 1, isoform CRA_a)FDFT1 hCG_17749Q6IAX15
Ferritin (Fragment)FTH1E9PPQ45
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]FGBQ32Q655
Fibrinogen gamma chainFGGC9JEU55
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)FGFR3 JTK4P226075
Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin)PKHD1 FCYT TIGM1P08F945
Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)FNDC3B FAD104 NS5ABP37 UNQ2421/PRO4979/PRO34274Q53EP05
Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)FNDC3A FNDC3 HUGO KIAA0970Q9Y2H65
FK506-binding protein 12 (Fragment)FKBP12Q3V7935
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1)FEN1 hCG_40848Q6FHX65
FLOT2 protein (Flotillin 2) (HCG1998851, isoform CRA_e)FLOT2 hCG_1998851Q6FG435
Forkhead-associated domain-containing protein 1 (FHA domain-containing protein 1)FHAD1 KIAA1937B1AJZ95
FRAS1-related extracellular matrix protein 1 (Protein QBRICK)FREM1 C9orf143 C9orf145 C9orf154Q5H8C15
Fructose-bisphosphate aldolase (EC 4.1.2.13)ALDOCA8MVZ95
Fructose-bisphosphate aldolase (EC 4.1.2.13)0B7Z1Y25
Fructose-bisphosphate aldolase (EC 4.1.2.13)0B7Z1N65
G protein-binding protein CRFG variant (Fragment)0Q53GS05
G-protein-signaling modulator 3 (Activator of G-protein signaling 4) (G18.1b) (Protein G18)GPSM3 AGS4 C6orf9 G18Q9Y4H45
GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60)GABPA E4TF1AQ065465
Galactosidase, alpha (Galactosidase, alpha, isoform CRA_a) (cDNA FLJ76285, highly similar to Homo sapiens galactosidase, alpha (GLA), mRNA)GLA hCG_20401Q53Y835
Galectin (Fragment)LGALS3Q6FGL05
Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3)GABRB3P284725
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)GABARAPL1 GEC1Q9H0R85
Gamma-glutamyltranspeptidase 1 (Fragment)GGT1E7ET765
Gamma-taxilin (Environmental lipopolysaccharide-responding gene protein) (Factor inhibiting ATF4-mediated transcription) (FIAT) (Lipopolysaccharide-specific response protein 5)TXLNG CXorf15 ELRG LSR5Q9NUQ35
Gamma-tubulin complex component0B4DYP75
Gamma-tubulin complex componentTUBGCP2F2Z2B95
GC-rich sequence DNA-binding factor 2 (GC-rich sequence DNA-binding factor) (Transcription factor 9) (TCF-9)GCFC2 C2orf3 GCF TCF9P163835
GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2)GFRA2 GDNFRB RETL2 TRNR2O004515
Gem-associated protein 4GEMIN4I3L2C75
Gem-associated protein 6 (Gemin-6) (SIP2)GEMIN6Q8WXD55
Gem-associated protein 7 (Gemin-7) (SIP3)GEMIN7Q9H8405
General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)GTF2H4Q927595
GH3 domain-containing proteinGHDC D11LGP1E LGP1Q8N2G85
Glucose-6-phosphate isomerase (Fragment)GPIK7EIL45
Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-)GFOD2 UNQ9430/PRO34691Q3B7J25
Glutamate dehydrogenase 1 variant (Fragment)0Q53GW35
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2)GDPD5 GDE2 PP6037 PP9363 UNQ1850/PRO3580Q8WTR45
Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))GLDC GCSPP233785
Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase)NMT2O605515
Granzyme K (EC 3.4.21.-) (Fragmentin-3) (Granzyme-3) (NK-tryptase-2) (NK-Tryp-2)GZMK TRYP2P498635
GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1)GCC1Q96CN95
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, isoform CRA_b (cDNA FLJ78702, highly similar to Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 2, mRNA) (cDNA, FLJ94539, Homo sapiens guanine nucleotide binding protein (G protein), alphaactivating activity polypeptide, olfactory type (GNAL), transcriptvariant 2, mRNA)GNAL hCG_1780858A8K1Y95
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