EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Probable maltase-glucoamylase 2 (Maltase-glucoamylase (alpha-glucosidase) pseudogene) [Includes: Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)]MGAM2C9JNC25
Prohibitin, isoform CRA_a (cDNA FLJ78511, highly similar to Homo sapiens prohibitin (PHB), mRNA) (cDNA, FLJ93035, Homo sapiens prohibitin (PHB), mRNA)PHB hCG_29613A8K4015
Prolactin (PRL)PRLP012365
Proliferating cell nuclear antigen (Fragment)PCNAQ7Z6A35
Prolyl endopeptidase (Prolyl oligopeptidase) (EC 3.4.21.26)0Q9UM025
Prostate stem cell antigen, isoform CRA_aPSCA hCG_38735D3DWI65
Proteasome assembly chaperone 10B2RD515
Proteasome subunit alpha type (EC 3.4.25.1)PSMA4H0YLC25
Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A)ABHD14A UNQ1913/PRO4373Q9BUJ05
Protein bicaudal C homolog 1 (Bic-C)BICC1Q9H6945
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)RUNX1T1 AML1T1 CBFA2T1 CDR ETO MTG8 ZMYND2Q064555
Protein cereblonCRBN AD-006Q96SW25
Protein Dok-7 (Downstream of tyrosine kinase 7)DOK7 C4orf25Q18PE15
Protein ELFN1 (Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1) (Protein phosphatase 1 regulatory subunit 28)ELFN1 PPP1R28P0C7U05
Protein FAM102A (Early estrogen-induced gene 1 protein)FAM102A C9orf132 EEIG1Q5T9C25
Protein FAM160B1FAM160B1 KIAA1600Q5W0V35
Protein FAM210AFAM210A C18orf19Q96ND05
Protein FAM98AFAM98AE9PH825
Protein IMPACT (Imprinted and ancient gene protein homolog)IMPACTQ9P2X35
Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1)NELL1 NRP1Q928325
Protein lifeguard 3 (Fragment)TMBIM1C9JEN35
Protein LTV1 homologLTV1 C6orf93Q96GA35
Protein LYRICMTDHE5RJU95
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)POMGNT1 MGAT1.2 UNQ746/PRO1475Q8WZA15
Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon)PPM1L PP2CEQ5SGD25
Protein S100 (S100 calcium-binding protein)0B2R5H05
Protein shisa-3 homologSHISA3A0PJX45
Protein Shroom1 (Apical protein 2)SHROOM1 APXL2 KIAA1960Q2M3G45
Protein sidekick-1SDK1F8W6X95
Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)TANC2 KIAA1148 KIAA1636Q9HCD65
Protein transport protein Sec24C (SEC24 related gene family, member C (S. cerevisiae), isoform CRA_b)SEC24C hCG_19035G5EA315
Protein unc-79 homologUNC79 KIAA1409Q9P2D85
Protein Wnt-11WNT11O960145
Protein Wnt-16WNT16Q9UBV45
Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5)TGM5 TGMXO435485
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (Fragment)PCMT1C9J0F25
Protocadherin gamma-C5 (PCDH-gamma-C5)PCDHGC5Q9Y5F65
Pseudopodium-enriched atypical kinase 1 (EC 2.7.10.2) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)PEAK1 KIAA2002Q9H7925
Pseudouridylate synthase 7 homolog-like protein (EC 5.4.99.-)PUS7LQ9H0K65
Pumilio homolog 2 (Pumilio-2)PUM2 KIAA0235 PUMH2Q8TB725
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1)MTAPQ05DJ25
Puromycin-sensitive aminopeptidase-like protein (EC 3.4.11.-)NPEPPSL1A6NEC25
Putative 60S ribosomal protein L39-like 5 (60S ribosomal protein L39 pseudogene 5)RPL39P5Q59GN25
Putative C-type lectin domain family 20 member ACLEC20A LINC00083 NCRNA00083Q6ZU455
Putative cytochrome b-c1 complex subunit Rieske-like protein 1 (Ubiquinol-cytochrome c reductase Rieske iron-sulfur subunit pseudogene 1)UQCRFS1P1 UQCRFSL1P0C7P45
Putative eukaryotic translation initiation factor 2 subunit 3-like protein (Eukaryotic translation initiation factor 2 subunit gamma A) (eIF-2-gamma A) (eIF-2gA)EIF2S3LQ2VIR35
Putative hydroxypyruvate isomerase (EC 5.3.1.22) (Endothelial cell apoptosis protein E-CE1)HYI HT036 SB156Q5T0135
Putative PDZ domain-containing protein PDZK1P1 (PDZ domain-containing 1 pseudogene 1) (PDZ domain-containing 1 pseudogene 2)PDZK1P1 PDZK1P2A8MUH75
Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1)ASXL1 KIAA0978Q8IXJ95
Putative uncharacterized protein (Fragment)0Q8WVW55
Putative uncharacterized protein DKFZp686A1765 (Tumor protein D52-like 2, isoform CRA_f) (cDNA FLJ54053, highly similar to Homo sapiens tumor protein D52-like 2 (TPD52L2), transcript variant 6, mRNA)DKFZp686A1765 TPD52L2 hCG_22755Q68E055
Putative uncharacterized protein DKFZp686M1483 (Fragment)DKFZp686M1483Q7Z3H25
Putative uncharacterized protein DKFZp779L0468DKFZp779L0468Q68DQ45
Putative uncharacterized protein RAB10 (Fragment)RAB10Q53SX45
Putative uncharacterized protein RAB6C (Rab6C) (WTH3DI)RAB6C Rab6C WTH3DIQ53S085
Putative uncharacterized protein XRCC5 (Fragment)XRCC5Q53T095
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-)PYROXD1Q8WU105
Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase)PGPEP1 PGPIQ9NXJ55
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)RABEP2 RABPT5BQ9H5N15
Ran-specific GTPase-activating protein (Fragment)RANBP1C9JDM35
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)RAPGEF2 KIAA0313 NRAPGEP PDZGEF1Q9Y4G85
Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4)RAP1GAP2 GARNL4 KIAA1039 RAP1GA2Q684P55
Ras and EF-hand domain-containing protein (Ras-related protein Rab-45)RASEF RAB45Q8IZ415
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)RIN1Q136715
Ras GTPase-activating-like protein IQGAP3IQGAP3F2Z2E25
Ras-related C3 botulinum toxin substrate 2RAC2B1AH775
Ras-related protein Rab-11B (GTP-binding protein YPT3)RAB11B YPT3Q6FHR05
Ras-related protein Rab-1BRAB1BE9PLD05
Ras-related protein Rab-34, isoform NARR (Nine amino-acid residue-repeats)RAB34 NARRP0DI835
Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)RAB40C RARL RASL8CQ96S215
Ras-related protein Rab-5C (L1880) (RAB5L)RAB5C RABLF8W1H55
Ras-related protein Ral-BRALBQ53T325
Ras-related protein Ral-B (Fragment)RALBC9JQB35
Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)RREB1 FINBQ927665
Receptor protein-tyrosine kinase (EC 2.7.10.1)0A8K2T75
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)FLT3 CD135 FLK2 STK1P368885
Regulating synaptic membrane exocytosis protein 3 (Nim3) (RIM3 gamma) (Rab-3-interacting molecule 3) (RIM 3)RIMS3 KIAA0237Q9UJD05
Regulator of G-protein signaling 14 (RGS14)RGS14O435665
Required for meiotic nuclear division protein 1 homologRMND1 C6orf96Q9NWS85
REV25-2 (Fragment)0A0N7J65
Rheumatoid factor G9 light chain (Fragment)V3A0N5G35
Rheumatoid factor RF-IP9 (Fragment)0A2J1M25
Rho GTPase activating protein0A9UK015
Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)ARHGAP25 KIAA0053P423315
Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8)ARHGAP8P852985
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)ARHGEF11 KIAA0380O150855
Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM)ARHGEF5 TIMQ127745
Rho guanine nucleotide exchange factor 7ARHGEF7B1ALK75
Rho-related GTP-binding protein RhoC (Fragment)RHOCQ5JR085
Rho-related GTP-binding protein RhoC (Fragment)RHOCE9PN115
Ribokinase (RK) (EC 2.7.1.15)RBKS RBSKQ9H4775
Ribosomal oxygenase 1 (60S ribosomal protein L8 histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66) (Myc-associated protein with JmjC domain) (Nucleolar protein 66) (hsNO66) (Ribosomal oxygenase NO66) (ROX)RIOX1 C14orf169 MAPJD NO66Q9H6W35
Ribosomal protein L27aL27aQ9BQQ55
Ribosomal protein S2RPS2Q3KQT65
Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)RPS6KA5 MSK1O755825
Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1) (Nucleomethylin)RRP8 KIAA0409 NML hucep-1O431595
RILP-like protein 2 (Rab-interacting lysosomal protein-like 2) (p40phox-binding protein)RILPL2 RLP2Q969X05
RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5)UNK KIAA1753 ZC3H5 ZC3HDC5Q9C0B05
RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variant (RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse))) (RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse)), isoform CRA_a) (cDNA FLJ77422, highly similar to Homo sapiens RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), transcript variant 1, mRNA) (Fragment)RALY hCG_37136Q53GL65
RNA pseudouridylate synthase domain-containing protein 2RPUSD2 C15orf19Q8IZ735
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